Clinical trials: Urinary Tract Infection (UTI)
Acute Infection
Diagnostic Accuracy of Urine Flow Cytometry in Excluding Bacteruria
A more rapid test for bacteriuria is desired. This will exclude the patients not having bacteriuria, which will contribute to a more rapid and accurate diagnosis of infectious diseases.
- Trial name
- NCT04686292
- Testing
- urine flow cytometry
- Where
- Denmark
- Volunteers
- 966 people
- Sponsor
- University of Southern Denmark
Overactive Bladder (OAB), Urinary Tract Infection (Diagnosis)
Methenamine Hippurate Following Intradetrusor OnabotulinumtoxinA Injection
The goal of this clinical trial is to compare methenamine hippurate prophylaxis to routine antibiotic prophylaxis following onabotulinumtoxinA (BOTOX-A) injections in women with overactive bladder (OAB).
- Trial name
- META (NCT06953271)
- Testing
- Methenamine Hippurate, Typically prescribed oral antibiotic prophylaxis
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Urinary Tract Infections
Prevention of Urinary Tract Infection (UTI) in Persons With Spinal Cord Injury (SCI)
Urinary tract infection (UTI) is the most common infection in patients with spinal cord injury (SCI) and is linked to major undesired results or complications including death.
- Trial name
- NCT00309114
- Testing
- bacterial interference
- Where
- 5 sites in United States
- Volunteers
- 65 people
- Sponsor
- Baylor College of Medicine
Urinary Catheter, Cesarean Section
Comparison of Immediate Versus Delayed Removal of Urinary Catheter Following Elective Cesarean Section
The objective this trial is to compare immediate and 12 hours postoperative removal of urinary catheter after elective cesarean section; and whether early removal is associated with lower risk of urinary infection compared with…
- Conditions
- Urinary Catheter, Cesarean Section, Urinary Infection
- Trial name
- NCT02074852
- Testing
- Foley urethral catheter
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Akmal El-Mazny
Complicated Urinary Tract Infection, Acute Pyelonephritis
Study of Cefepime-zidebactam (FEP-ZID) in Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP)
This is a Phase 3, randomized, double-blind, multicenter, non-inferiority study to evaluate the efficacy, safety, and tolerability of FEP-ZID vs. meropenem in the treatment of hospitalized adults with cUTI or AP.
- Trial name
- NCT04979806
- Testing
- Cefepime-zidebactam (FEP-ZID), Meropenem
- Where
- 48 sites in United States, Bulgaria and 7 more
- Volunteers
- 530 people
- Sponsor
- Wockhardt
Postoperative Urinary Tract Infection
Function of Tamsulosin in Older Males Undergoing Surgery With Indwelling Catheter
This study is being done to answer the question: What is the impact of a medication called tamsulosin (also called Flomax) on the rate of postoperative urinary retention (POUR) and catheter-associated urinary tract infection…
- Trial name
- FOLI (NCT06257576)
- Testing
- Tamsulosin, Control Group
- Where
- 4 sites in United States
- Volunteers
- 87 people
- Sponsor
- Emory University
Catheter Associated Urinary Tract Infection
REPLACE: The Impact of Catheter Replacement in Patients With Catheter-associated Urinary Tract Infection
With this project the investigators aim to address the following question: "Is it beneficial to change bladder catheters during urinary tract infections?" There is debate regarding the usefulness of changing an indwelling…
- Trial name
- NCT06936631
- Testing
- Catheter replacement, Catheter retainment
- Where
- Netherlands
- Volunteers
- 300 people
- Sponsor
- Leiden University Medical Center
Acute Uncomplicated Bacterial Cystitis
Epidemiology of Acute Bacterial Uncomplicated Cystitis in General Practice
Acute uncomplicated bacterial cystitis is common in general practice. Cystitis is at the second raw of antibiotic treatment indications.
- Trial name
- BaCyst (NCT00958295)
- Where
- France
- Volunteers
- 362 people
- Sponsor
- University Hospital, Rouen
Complicated Urinary Tract Infection, Acute Pyelonephritis
Study to Assess the Efficacy, Safety and Pharmacokinetics of Orally Administered Tebipenem Pivoxil Hydrobromide (SPR994) Compared to Intravenous Ertapenem in Participants With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP)
The key purpose of this study is to evaluate the efficacy, safety and pharmacokinetics (PK) of tebipenem pivoxil hydrobromide (TBPM-PI-HBr) compared to intravenous (IV) ertapenem, in participants with complicated Urinary Tract…
- Trial name
- ADAPT-PO (NCT03788967)
- Testing
- TBPM-PI-HBr, Ertapenem, Dummy Infusion
- Where
- 96 sites in United States, Bulgaria and 13 more
- Volunteers
- 1,372 people
- Sponsor
- Spero Therapeutics
Pyelonephritis Acute
Diagnostic Imaging of Acute Pyelonephritis
Acute pyelonephritis is important to recognize and treat quickly. Today the diagnosis is primarily clinical and often challenging. Sometimes acute pyelonephritis is complicated by obstruction leading to hydronephrosis.
- Trial name
- NCT04651244
- Testing
- MRI, Ultrasound performed by a radiologist, Point of care ultrasound
- Where
- Denmark
- Volunteers
- 19 people
- Sponsor
- University of Southern Denmark
Urinary Tract Infections
Cross-sectional Survey on Patients With Urinary Tract Infections in Puy-de-Dôme : Epidemiology of Recurrent Urinary Tract Infections and Risk Factors
Urinary tract infections (UTI) are an important part of infectious diseases. For some patients, those infections are recurrent and have many consequences such as altered quality of life, recurrent symptoms, antibiotics overuse……
- Trial name
- IUR63 (NCT04361864)
- Where
- France
- Volunteers
- 561 people
- Sponsor
- University Hospital, Clermont-Ferrand
Recurrent Clostridium Difficile Infection, Multidrug-resistant Klebsiella Pneumoniae Urinary Tract Infection
Fecal Microbiota Transplantation (FMT): PRIM-DJ2727
The Fecal Microbiota Transplantation (FMT) product PRIM-DJ2727 is prepared from human stool from a healthy, screened donor. Requestors will contact the study team about the product (PRIM-DJ2727) by email, visit, or phone call.
- Trial name
- NCT03786900
- Testing
- Fecal Microbiota Transplantation (FMT) product PRIM-DJ2727
- Sponsor
- Herbert DuPont, MD
Urinary Tract Infections
UTI Prophylaxis Using Bacterial Interference Following SCI
Urinary tract infection (UTI) is the most common infection in patients with SCI and is a major cause of morbidity and mortality in this population.
- Trial name
- NCT00037921
- Testing
- Bacterial colonization
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- US Department of Veterans Affairs
Urinary Tract Infections
Safety and Efficacy Study of Cefepime-AAI101 in the Treatment of Complicated Urinary Tract Infections
Multi-center, randomized, double-blind, non-inferiority study of cefepime 2 g/AAI101 500 mg combination compared to piperacillin 4 g/tazobactam 500 mg in a population of adult patients with cUTI or AP.
- Trial name
- NCT03687255
- Testing
- cefepime/AAI101 combination, Piperacillin/tazobactam
- Where
- 24 sites in United States, Argentina and 17 more
- Volunteers
- 1,043 people
- Sponsor
- Allecra
Urinary Tract Infections, Malnutrition
Effect of Hygiene and Menstrual Hygiene Interventions on Learning and Psychosocial Wellbeing in Madagascar
A previous study in schools in rural Madagascar found that a bundle of hygiene-focused interventions substantially improved girls' learning outcomes.
- Conditions
- Urinary Tract Infections, Malnutrition, Inflammation, Stress
- Trial name
- KILONGA2 (NCT07702916)
- Testing
- Peer leadership/sensitization + sanitary pads, School infrastructure
- Where
- Madagascar
- Volunteers
- 3,080 people, healthy volunteers welcome
- Sponsor
- University of California Santa Cruz
Urinary Tract Infections, Bladder, Neurogenic
A Biochip for Rapid Diagnosis of Complicated Urinary Tract Infection
The purpose of this proposal is clinical validation of an electrochemical biochip for rapid pathogen identification and antibiotic susceptibility determination.
- Trial name
- NCT00591240
- Where
- United States
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Urinary Tract Infection
Cranberry for UTI Prevention in Residents of Long Term Care Facilities
Urinary tract infections (UTIs) affect over 7 million men and women per year and cost the health care industry over 1 billion dollars annually.
- Trial name
- PACS (NCT00596635)
- Testing
- Once Daily Cranberry Capsule, Twice Daily Cranberry Capsules
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Yale University
Urinary Tract Infections, Infection
Effects of a Cranberry Beverage on Women With Recent History of Urinary Tract Infections
The purpose of this study is to compare the effects of a cranberry juice beverage on rates of Urinary tract infection (UTI) recurrence in women with a history of UTI.
- Conditions
- Urinary Tract Infections, Infection, Urologic Diseases
- Trial name
- NCT01776021
- Testing
- cranberry juice
- Where
- 17 sites in United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Ocean Spray Cranberries, Inc.
Cross Infection, Bacteriuria
Prevention of Nosocomial E. Coli Infections After Placement of an Indwelling Catheter During Pelvic Surgery: an Evaluation of Cranberry Gel Capsules
Indwelling urinary catheters are a primary site for nosocomial infections. The purpose of this study is to evaluate the anti-adhesive properties of Cranberry type A pro anthocyanidine gel capsules in the prevention Escherichia…
- Trial name
- NosoPink (NCT01114347)
- Testing
- cranberry type A pro anthocyandines
- Where
- France
- Volunteers
- 270 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Urinary Tract Infections
Modified Reporting From Indwelling Catheters
Positive urine cultures collected from indwelling catheters from inpatients will be randomized to standard reporting or modified reporting.
- Trial name
- NCT03488355
- Testing
- Modified laboratory report
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Memorial University of Newfoundland