Clinical trials: Urinary Tract Infection (UTI)
Urinary Retention
The Effect of Tamsulosin on Postoperative Urinary Retention
This is a double-blinded randomized controlled trial of perioperative use of tamsulosin to prevent postoperative urinary retention in female pelvic reconstructive surgery undergoing same-day discharge with an enhanced recovery…
- Trial name
- NCT04682366
- Testing
- Tamsulosin
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Wake Forest University Health Sciences
Urinary Tract Infection
Peripartum Bacteruria and Urinary Tract Infections (UTI)
In the last years urinary tract infections (UTI) and pyelonephritis have been the most common reason for readmission to our hospital after birth.
- Trial name
- NCT00121797
- Testing
- urine culture, antibiotics according to culture
- Where
- 2 sites in Israel
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Infection Associated With Catheter, Urinary Tract Infection
Silver-impregnated Suprapubic Catheters (SPC) in Urogynecology
The purpose of this study is to compare urinary tract infection rates among women undergoing urogynecological procedures with a silver-alloy suprapubic catheter compared to the standard suprapubic catheter.
- Trial name
- NCT01359046
- Testing
- silver SPC, standard SPC
- Where
- United States
- Volunteers
- 288 people
- Sponsor
- Mayo Clinic
Urinary Tract Infections (UTIs)
The Efficacy of Orally Administrated Probiotic Formula in Preventing a Recurrence of a Urinary Tract Infection During Pregnancy
Background: Urinary tract infections (UTIs), the most common infection in pregnancy,are associated with several maternal and fetal complications, including maternal septic shock, preterm labor, intrauterine growth restriction and…
- Trial name
- NCT02637986
- Testing
- Urex Plus - containing L. rhamnosus GR-1 and L. reuteri RC-14
- Sponsor
- HaEmek Medical Center, Israel
Antibiotic Sensitivity Testing and Genotypic Caharacterization of Ecoli
Phenotypic and Genotypic Characterization of Escherichia Coli
Collection of urine samples Cultivation Antibiotic sensitivity test PCR
- Trial name
- NCT06462261
- Volunteers
- 100 people
- Sponsor
- Sohag University
Urological Disease, Radical Cystectomy
Evaluate the Efficacy and Safety of Prevention of Infection Foley Catheter as Compared to Conventional Foley Catheter
Comparison of effectiveness and safety of infection prevention silicone urinary catheters and conventional catheters for patients scheduled to perform urinary catheterization after radical cystectomy for urological diseases for…
- Trial name
- NCT04152720
- Testing
- Foley catheter
- Where
- South Korea
- Volunteers
- 160 people
- Sponsor
- Seoul National University Hospital
Complicated Urinary Tract Infection
A Study to Investigate PK, Safety, Tolerability of Cefepime-enmetazobactam in Pediatric Participants With cUTI
This phase 2 study is part of regulatory commitments in the United States (PSP) and Europe (PIP) to evaluate cefepime-enmetazobactam in paediatric participants with cUTI to support extension of the indication for…
- Trial name
- NCT05826990
- Testing
- cefepime and enmetazobactam combination
- Where
- 8 sites in Czechia, France and 4 more
- Volunteers
- 40 people
- Sponsor
- Orchid Pharma Europe GmbH
Urinary Tract Infections, Bladder Cancer
Comparative Microbial Analysis of Cystitis in Non-muscle-invasive Bladder Cancer Patients Using Vikor Scientific Urine-ID Testing Menu (IDTM) and Standard Laboratory Culture
Vikor Scientific Urine-IDTM is a molecular analysis technology which provides pathogen detection, quantification, and resistance gene identification.
- Trial name
- VS-UrineID (NCT04583553)
- Testing
- Vikor Scientific Urine-IDTM
- Where
- United States
- Sponsor
- University of Kansas Medical Center
Bacteriuria
A Pilot Study To Assess The Impact Of A Camstent Coated Catheter On Clinical Bacteriuria
A Pilot Study To Assess The Impact Of A Camstent Coated Catheter On Clinical Bacteriuria when compared to an uncoated catheter. Each participant will take part in the trial from the time the participant signs the informed consent…
- Trial name
- CAM-SPC-001 (NCT04658719)
- Testing
- Camstent Coated Catheter, Standard Care
- Volunteers
- 30 people
- Sponsor
- Camstent Ltd.
Recurrent Uti
Intravesical Gentamicin to Prevent Recurrent UTI
Feasibility assessment of intravesical gentamicin instillation (putting antibiotics directly into the bladder) versus the current standard of care of oral nitrofurantoin prophylaxis (taking a low dose of antibiotics by mouth…
- Trial name
- NCT06332781
- Testing
- Gentamicin, Nitrofurantoin
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Urinary Tract Infections
Fosfomycin Versus Standard of Care in Children With Antibiotic-resistant Urinary Tract Infections
Urinary tract infections (UTIs) are among the most common bacterial infections in children. Up to 50% of UTI's are caused by multi-drug resistant ESBL-producing gram negative bacteria that do not respond to treatment with oral…
- Trial name
- FosUTI (NCT05709028)
- Testing
- Fosfomycin, Standard of care antibiotics
- Where
- 5 sites in Australia
- Volunteers
- 300 people
- Sponsor
- University of Sydney
Acute Lower Urinary Tract Infection
A Multi-center, Randomized, Double-blind, Double-dummy Clinical Study to Evaluate the Safety and Efficacy of Prulifloxacin Film-coated Tablet for the Treatment of Acute Uncomplicated Lower Urinary Tract Infection With Levofloxacin Hydrochloride Tablet as Active Control
prulifloxacin is not inferior to levofloxacin hydrochloride in treating acute uncomplicated lower urinary tract infection in chinese
- Trial name
- NCT02439632
- Testing
- prulifloxacin, Levofloxacin
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Lee's Pharmaceutical Limited
Urinary Tract Infection, Acute Pyelonephritis
Efficacy and Safety of CAZ-AVI in the Treatment of Infections Due to Carbapenem-resistant G- Pathogens in Chinese Adults
This is an open-label, randomized, multi-center, interventional, active-controlled Phase 4 study to evaluate the efficacy and safety of CAZ-AVI versus BAT in the treatment of infected participants with selected infection types…
- Conditions
- Urinary Tract Infection, Acute Pyelonephritis, Hospital Acquired Pneumonia, Ventilator-associated Pneumonia
- Trial name
- NCT04882085
- Testing
- Zavicefta, Ceftazidime-Avibactam, Best Available Treatment
- Where
- 37 sites in China
- Volunteers
- 60 people
- Sponsor
- Pfizer
Helicobacter Infections, Urinary Tract Infection
First Time in Man Study of Finafloxacin Hydrochloride
The purpose of this study is to study the safety of single doses and multiple doses of Finafloxacin hydrochloride in healthy volunteers. The level of Finafloxacin hydrochloride will be measured in the subjects blood and urine.
- Trial name
- NCT00483158
- Testing
- Finafloxacin hydrochloride
- Where
- Switzerland
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- MerLion Pharmaceuticals GmbH
Type 2 Diabetes Mellitus (T2DM), Recurrent Urinary Tract Infections
Cranberry Proanthocyanidins and Lactobacilli for Recurrent UTI Prevention in Type 2 Diabetes
The purpose of this prospective, single-arm feasibility study was to evaluate the operational feasibility, tolerability, safety, and exploratory clinical outcomes of an oral supplement combining standardized cranberry…
- Trial name
- NCT07832409
- Testing
- Cranberry Proanthocyanidins and Lactobacilli
- Where
- Georgia
- Volunteers
- 100 people
- Sponsor
- National Institute of Endocrinology, Georgia
Overactive Bladder Syndrome
Overactive Bladder Syndrome: Incobotulinumtoxin Versus Onabotulinumtoxin
The aim of the original study was to compare Incobot/A versus Onabot/A in order to evaluate if the differences in the pharmacologic formulations between the two drugs could affect their efficacy and safety in the treatment of…
- Trial name
- NCT03758235
- Testing
- IncobotulinumtoxinA 100 UNT Injection [Xeomin], OnabotulinumtoxinA 100 UNT [Botox]
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- University Of Perugia
Schistosomiasis Haematobia
Nanobody-based Schistosomiasis Urine Test Kit Research
This study aims to develop and evaluate a nanobody-based urine diagnostic test for Schistosoma haematobium infection through IPSE antigen detection.
- Trial name
- NCT07500740
- Testing
- Because this is an observational study, participants are not assigned an intervention as part of the study.
- Where
- Tanzania
- Volunteers
- 2,500 people
- Sponsor
- Pemba Ministry of Health Zanzibar
Overactive Bladder, Urinary Tract Infections
Comparison of Methods for Prevention of Urinary Tract Infection Following Botox Injection
Injection of OnabotulinumtoxinA (BTX-A) into the bladder is a widely used treatment option for patients with overactive bladder who have failed medical therapy.
- Trial name
- NCT03508921
- Testing
- Periprocedural Antibiotics, Extended Antibiotics, Injection of OnabotulinumtoxinA (BTX-A)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Vanderbilt University Medical Center
Chronic Urinary Tract Infection
A Clinical Trial of Extended (High) Treatment Dose Antibiotics in Combination With Methenamine Hippurate Compared to the Standard of Care (Either Prophylactic (Low) Dose Antibiotic Treatment or Methenamine Hippurate) in Females With Chronic Urinary Tract Infection
Chronic Urinary Tract Infection (UTI) is a type of UTI where symptoms are constant and occur every day, unlike recurrent UTIs, which come and go with symptom-free breaks in between.
- Trial name
- EAT-UP (NCT07202949)
- Testing
- Treatment dose antibiotic in combination with methenamine hippurate, Prophylactic dose antibiotic or methenamine hippurate monotherapy
- Where
- 5 sites in United Kingdom
- Volunteers
- 192 people
- Sponsor
- University College, London
Neurogenic Bladder
Assess the Efficacy of OM-89 vs Placebo in Reducing Antibiotic Consumption Associated With the Treatment of Urinary Tract Infections in Patients With Neurogenic Bladder
Recurrent urinary tract infections (UTIs) in patients with a neurogenic bladder using clean intermittent catheterization (CIC) are a major problem.
- Trial name
- RETRAIN (NCT06588010)
- Testing
- OM-89 [Uro-Vaxom® Capsule]
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Centre Hospitalier Universitaire Dijon