Clinical trials: Urinary Tract Infections, Recurrent
Recurrent Urinary Tract Infection, Urinary Tract Infections
Preventing Recurrent UTI With Vaginal Estrogen
Among postmenopausal women who suffer from recurrent urinary tract infections (UTI), vaginal estrogen therapy prevents UTI recurrences for 50% of sufferers.
- Conditions
- Recurrent Urinary Tract Infection, Urinary Tract Infections, Cystitis Recurrent
- Trial name
- PRUVE (NCT05551949)
- Testing
- Vaginal estradiol tablets
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Johns Hopkins University
Urinary Tract Infection
Suppressive Therapy With Oral Antibiotics for Prevention of Postoperative Urinary Tract Infection (UTI)
This is a study of patients undergoing gynecologic surgery who require post-operative catheterization to determine if prophylactic antibiotic treatment decreases the risk of post-operative urinary tract infection in these…
- Trial name
- STOPP UTI (NCT01450800)
- Testing
- Nitrofurantoin
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- Duke University
Common Infections, Urinary Tract Infections
Dissemination and Implementation of a Videoconference Antimicrobial Stewardship Team
Antimicrobial-resistant and healthcare-associated pathogens are a global health threat. The goals of antimicrobial stewardship are to minimize unnecessary and inappropriate antimicrobial use as a means to combat antimicrobial…
- Conditions
- Common Infections, Urinary Tract Infections, Pneumonia
- Trial name
- VAST (NCT05319561)
- Testing
- Antibiotic Use Report
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- VA Office of Research and Development
Urinary Tract Infections
Cytoscopic Antibiotic Irrigant to Reduce Postoperative Urinary Tract Infection
Postoperative urinary tract infections (UTIs) affect 20-30% of patients undergoing elective gynecologic surgery and have a significant socioeconomic impact and cost.
- Trial name
- NCT03099863
- Testing
- Cystoscopic Fluid containing Neosporin G. U. Irrigant, Cystoscopy
- Where
- United States
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Complicated Urinary Tract Infection
Safety and Efficacy of IV CXA-101 and IV Ceftazidime in Patients With Complicated Urinary Tract Infections
The purpose of this study is to evaluate the safety and efficacy of intravenous CXA 101 and comparator in complicated urinary tract infection
- Trial name
- NCT00921024
- Testing
- CXA-101, Ceftazidime
- Where
- 21 sites in United States, Germany and 1 more
- Volunteers
- 129 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Respiratory Tract Infections, Urinary Tract Infections
Study on Cefotaxime and Sulbactam Sodium for Injection (2:1) for Treatment of Respiratory and Urinary Tract Infection
In the proposed study, the investigators plan to evaluate the efficacy and safety of Cefotaxime sodium and sulbactam sodium for injection (2:1)for the treatment of respiratory and urinary tract acute bacterial infection under the…
- Trial name
- SWSB (NCT01426191)
- Testing
- xinzhijun
- Volunteers
- 2,032 people
- Sponsor
- Xiangbei Welman Pharmaceutical Co., Ltd
Infection Associated With Catheter, Urinary Tract Infection
Silver-impregnated Suprapubic Catheters (SPC) in Urogynecology
The purpose of this study is to compare urinary tract infection rates among women undergoing urogynecological procedures with a silver-alloy suprapubic catheter compared to the standard suprapubic catheter.
- Trial name
- NCT01359046
- Testing
- silver SPC, standard SPC
- Where
- United States
- Volunteers
- 288 people
- Sponsor
- Mayo Clinic
Urinary Tract Infections
Fractional CO2 Vaginal LASER Therapy for Recurrent Urinary Tract Infection
Randomized controlled trial to determine clinical and microbiome difference between fractional CO2 Laser and vaginal estrogen in treating patients with recurrent urinary tract infection (UTI).
- Trial name
- NCT04301934
- Testing
- Mona Lisa Touch, Conjugated estrogen, Estradiol
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Mayo Clinic
Infection, Cross Infection
A Safety and Efficacy Study of Doripenem in Participants With Nosocomial Pneumonia, Complicated Intra-Abdominal Infections and Urinary Tract Infections
The purpose of this study is to assess the safety and efficacy of doripenem in participants with nosocomial pneumonia (inflammation of the lungs in which the lungs become heavy; pneumonia occurring at least 48 hours after…
- Conditions
- Infection, Cross Infection, Bacterial Infections, Pneumonia, Ventilator-Associated
- Trial name
- NCT00965848
- Testing
- Doripenem
- Where
- 8 sites in Thailand
- Volunteers
- 270 people
- Sponsor
- Janssen-Cilag Ltd.,Thailand
Urinary Tract Infections, Spinal Cord Injuries
Gentamicin Bladder Instillations to Prevent Urinary Tract Infections in Patients With Spinal Cord Injury
A non-randomized study evaluating the efficacy of intravesical gentamicin on the occurrence rate of urinary tract infections and bladder complications in patients after spinal cord injury (SCI), and to assess its effectiveness in…
- Conditions
- Urinary Tract Infections, Spinal Cord Injuries, Spinal Cord Diseases, Neurogenic Bladder
- Trial name
- NCT03503513
- Testing
- Gentamicin Sulfate
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Michigan
Urinary Tract Infections
Modified Reporting From Indwelling Catheters
Positive urine cultures collected from indwelling catheters from inpatients will be randomized to standard reporting or modified reporting.
- Trial name
- NCT03488355
- Testing
- Modified laboratory report
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Memorial University of Newfoundland
Spinal Cord Injury, Urinary Tract Infection
Colonizing Neurogenic Bladders With Benign Flora
The purpose of the research is to determine whether we can get harmless bacteria to live in the bladders of persons with spinal cord injury who practice intermittent bladder catheterization.
- Trial name
- NCT00371631
- Testing
- Insertion of urinary catheters coated with E. coli 83972
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- US Department of Veterans Affairs
Urinary Tract Infection, Vesicoureteral Reflux
Contrast Enhanced Ultrasound for Evaluation of Reflux Nephropathy
The study will be evaluating the efficacy and safety of a contrast drug in pediatric renal ultrasound.
- Trial name
- NCT02786810
- Testing
- Sulfur hexafluoride type-a lipid microspheres
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Urinary Tract Infection, Infection Due to ESBL Bacteria
Extended Spectrum Betalactamase Producing Bacteria; Epidemiology and Treatment in Non-hospitalized Patients
This project aims at investigating the duration of human fecal carriage of bacteria harboring plasmid-borne resistance genes expressing Extended Spectrum beta-lactamases (ESBL), risk factors for infections with such bacteria and…
- Conditions
- Urinary Tract Infection, Infection Due to ESBL Bacteria, Environmental Contamination of ESBL
- Trial name
- ESCAPE (NCT01838213)
- Volunteers
- 760 people
- Sponsor
- Vestre Viken Hospital Trust
Cancer
Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain
This is a phase III, randomized, double-blind, placebo-controlled, multicenter study of the clinical response to fentanyl sublingual spray as a treatment for breakthrough cancer pain.
- Trial name
- NCT00538850
- Testing
- Fentanyl sublingual spray
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- INSYS Therapeutics Inc
Complicated Urinary Tract Infection, Acute Pyelonephritis
Evaluation of Safety and Efficacy of Intravenous Sulbactam-ETX2514 in the Treatment of Hospitalized Adults With Complicated Urinary Tract Infections
This study is a double-blind, randomized, placebo-controlled study to evaluate the safety and efficacy of IV ETX2514SUL in patients with complicated urinary tract infections (cUTIs) who are otherwise relatively healthy.
- Trial name
- NCT03445195
- Testing
- Sulbactam-ETX2514, Imipenem-cilastatin
- Where
- 4 sites in Bulgaria
- Volunteers
- 80 people
- Sponsor
- Entasis Therapeutics
Urinary Tract Infection, Acute Pyelonephritis
A Study of Oral Tebipenem Pivoxil Hydrobromide (TBP-PI-HBr) Compared to Intravenous Imipenem-cilastatin in Participants With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP)
The primary purpose of this study is to assess the efficacy of oral TBP-PI-HBr as compared with intravenous (IV) imipenem-cilastatin with respect to the overall response (combined clinical cure plus microbiological eradication)…
- Trial name
- PIVOT-PO (NCT06059846)
- Testing
- TBP-PI-HBr, Imipenem-cilastatin, Dummy Infusion
- Where
- 85 sites in United States, Argentina and 17 more
- Volunteers
- 1,690 people
- Sponsor
- Spero Therapeutics
Urinary Tract Infection
Efficacy of Micro-Patterned Foley Catheter to Reduce Catheter-Associated Urinary Tract Infection
The purpose of this study is to determine if the study Foley catheter with its patterned external surface can delay the time to the onset of urinary tract infection in spinal cord injury patients who are dependent on a Foley…
- Trial name
- NCT02198833
- Testing
- Urine Culture, Foley Catheter Tip Culture, Scanning Electron Microscopy
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- Baylor College of Medicine
Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis
Ceftazidime-Avibactam Compared With Doripenem Followed by Oral Therapy for Hospitalized Adults With Complicated UTIs (Urinary Tract Infections)
The purpose of this study is to evaluate the effects of Ceftazidime Avibactam compared to Doripenem for treating hospitalized patients with complicated urinary tract infections, including acute pyelonephritis
- Trial name
- NCT01595438
- Testing
- Ceftazidime - Avibactam ( CAZ-AVI), Doripenem, Either switch to oral therapy: 500 mg of Ciprofloxacin (oral)
- Where
- 80 sites in United States, Argentina and 20 more
- Volunteers
- 598 people
- Sponsor
- Pfizer
Bladder Carcinoma, Refractory Bladder Carcinoma
Prophylactic Antibiotics for Urinary Tract Infections After Robot-Assisted Radical Cystectomy
This trial investigates whether a one-month course of preventative (prophylactic) antibiotics helps to reduce urinary tract infections after robot-assisted surgery to remove all of the bladder as well as nearby tissues and organs…
- Conditions
- Bladder Carcinoma, Refractory Bladder Carcinoma, Urinary Tract Infection
- Trial name
- NCT04502095
- Testing
- Clindamycin, Diary, Ertapenem
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Roswell Park Cancer Institute