Clinical trials: Urogenital
Bedwetting
Hand & Foot Nocturnal Enuresis TENS Study
The investigators believe in order to strengthen the evidence in support of transcutaneous foot stimulation in this population the investigators need to move forward with a randomized comparison study using the TENS device on the…
- Trial name
- NCT02747849
- Testing
- TENS
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Rajeev Chaudhry
Cardiovascular-kidney-metabolic Syndrome, Cardiovascular Diseases
Inspire HER: Inspiring the Heart and Emotions for Radical Health
Poor heart health puts Black women at risk for a shorter life with more illness than people of any other non-indigenous racial group.
- Conditions
- Cardiovascular-kidney-metabolic Syndrome, Cardiovascular Diseases, Hypertension, Diabetes
- Trial name
- NCT06966258
- Testing
- Inspire HER Intervention
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Alabama at Birmingham
HIV Infections
Maraviroc in Immunological Non-Responder (INR) HIV-1-infected Subjects
Suboptimal improvement in cluster of differentiation 4 (CD4) cell count is not uncommon in HIV-1-infected patients with suppressed plasma HIV-Ribonucleic acid (RNA) levels, and a decrease in CD4 cell count in patients with…
- Trial name
- NCT00884858
- Testing
- Maraviroc
- Where
- 20 sites in Italy
- Volunteers
- 100 people
- Sponsor
- ASST Fatebenefratelli Sacco
Clear Cell Renal Cell Carcinoma, Recurrent Renal Cell Carcinoma
Everolimus With or Without Bevacizumab in Treating Patients With Advanced Kidney Cancer That Progressed After First-Line Therapy
This randomized phase III trial studies giving everolimus together with bevacizumab to see how well it works compared to everolimus alone in treating patients with advanced kidney cancer that progressed after first-line therapy.
- Conditions
- Clear Cell Renal Cell Carcinoma, Recurrent Renal Cell Carcinoma, Stage III Renal Cell Cancer AJCC v7, Stage IV Renal Cell Cancer AJCC v7
- Trial name
- NCT01198158
- Testing
- Bevacizumab, Everolimus, Laboratory Biomarker Analysis
- Where
- 524 sites in United States
- Volunteers
- 77 people
- Sponsor
- National Cancer Institute (NCI)
Prostate Cancer
Prostate Cancer E-Health-Tutorial
In a participatory process involving urologists and former patients, the project team has developed an online information system ("tutorial") for patients with localized prostate cancer.
- Trial name
- PROCET (NCT02503748)
- Testing
- Online tutorial
- Where
- 8 sites in Switzerland
- Volunteers
- 53 people
- Sponsor
- Zurich University of Applied Sciences
Metastatic Prostate Cancer
Psma Intensity Can be Altered by Androgen and Phospho-SrC Obstruction
The study's purpose is to understand the appearance of your prostate-specific membrane antigen (PSMA) PET scan after you take 14 days of treatment with a drug called dasatinib alone or in combination with anti-testosterone drug…
- Trial name
- PICASSO (NCT04925648)
- Testing
- Dasatinib, Darolutamide
- Where
- 2 sites in Australia
- Volunteers
- 4 people
- Sponsor
- St Vincent's Hospital, Sydney
Acute Renal Colic, Nephrolithiasis
Conditional Imaging Prescription Strategy for Exploration of Acute Uncomplicated Renal Colic
Prospective single centre study aiming at validating a conditional imaging strategy for diagnosis of suspected kidney stone. Consecutive Emergency department patients referred to the medical imaging department for exploration of…
- Trial name
- IMAGENCO (NCT02878148)
- Testing
- Diagnostic imaging modalities for suspected renal colic
- Where
- France
- Volunteers
- 220 people
- Sponsor
- University Hospital, Montpellier
Prostatic Hyperplasia
FLOMAX® Versus HYTRIN® in Patients With the Signs and Symptoms of Benign Prostatic Hyperplasia
1. To study the early onset of symptomatic relief afforded by FLOMAX® capsules, 0.4 mg daily as compared to HYTRIN® capsules, 5 mg (with titration) daily in patients with the signs and symptoms of benign prostatic hyperplasia…
- Trial name
- NCT02244255
- Testing
- FLOMAX® capsules, Ascending doses of HYTRIN® capsules
- Volunteers
- 1,993 people
- Sponsor
- Boehringer Ingelheim
Acute Kidney Injury
The Effect of Sodium Bicarbonate on Postoperative Renal Function in Infective Endocarditis Patients Undergoing Open Heart Surgery
The purpose of study is to test whether perioperative sodium bicarbonate infusion can prevent acute kidney injury following open heart surgery in infective endocarditis patients.
- Trial name
- NCT01920126
- Testing
- sodium bicarbonate, Saline
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Yonsei University
Recurrent Endometrial Carcinoma
VEGF Trap in Treating Patients With Recurrent or Persistent Endometrial Cancer
This phase II trial is studying the side effects and how well VEGF Trap works in treating patients with recurrent or persistent endometrial cancer.
- Trial name
- NCT00462826
- Testing
- ziv-aflibercept
- Where
- 67 sites in United States
- Volunteers
- 49 people
- Sponsor
- National Cancer Institute (NCI)
Prostate Cancer
Hypofractionated Radiotherapy for Prostate Cancer
Radiotherapy is a standard definitive treatment for men with localized prostate cancer. Recent improvements in technology allow high doses of radiation to be delivered to the prostate in less days with lower doses to surrounding…
- Trial name
- HRT20 (NCT03851926)
- Testing
- Hypofractionated volumetric radiotherapy in 20 fractions
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Consorci Sanitari de Terrassa
IGA Glomerulonephritis
Inhibitors of Angiotensin II in Proteinuric Mesangioproliferative Glomerulonephritis
This study evaluates prospectively the effects of an anti-angiotensin II regimen on renal outcome in patients with mesangioproliferative glomerulonephritis followed-up for 10 years.
- Trial name
- NCT01115426
- Testing
- Ramipril or losartan
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University Magna Graecia
Premature Birth, Sedation During Labor and Delivery; Complications, Pulmonary
Magnesium for Neonatal Neuroprotection and Mothers
Magnesium is a treatment for mothers to protect brains of babies born early. This study investigates combined effects of magnesium and spinal or epidural anesthesia on mothers having cesareans.
- Conditions
- Premature Birth, Sedation During Labor and Delivery; Complications, Pulmonary, Respiratory Depression
- Trial name
- MnMs (NCT01482078)
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of British Columbia
Kidney Stone
Reducing Opioid Prescription After Kidney Stone Removal Surgery
The purpose of this study is to implement and assess a standard way of prescribing opioid pain medication following PCNL (a kidney stone removal surgery) to ensure patients are being discharged with an appropriate quantity of…
- Trial name
- NCT05353478
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Mayo Clinic
Metastatic Cancer, Prostate Cancer
Docetaxel With or Without Imatinib Mesylate in Treating Patients With Androgen-Independent Prostate Cancer and Bone Metastases
RATIONALE: Drugs used in chemotherapy, such as docetaxel, work in different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00080678
- Testing
- Docetaxel, Imatinib Mesylate
- Where
- 3 sites in United States
- Volunteers
- 116 people
- Sponsor
- M.D. Anderson Cancer Center
Interstitial Cystitis, Painful Bladder Syndrome
Omalizumab in Interstitial Cystitis/Bladder Pain Syndrome
By hypothesising that Interstitial Cystitis is an allergic disorder of the urogenital system that is linked to mast-cells, current therapy with omalizumab may represent a potential non symptomatic strategy for the treatment of…
- Trial name
- IComaliz (NCT01294878)
- Testing
- omalizumab
- Where
- Italy
- Volunteers
- 3 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Urinary Incontinence
Athena Pelvic Muscle Trainer - DUETS Trial
The purpose of this study is to determine if the Athena Pelvic Muscle Trainer device effectively treats stress, urge or mixed incontinence in women by strengthening the pelvic floor muscles by collecting data from the patient on…
- Trial name
- DUETS (NCT01073878)
- Testing
- Athena Pelvic Muscle Trainer
- Where
- 97 sites in United States, Virgin Islands
- Volunteers
- 462 people
- Sponsor
- Athena Feminine Technologies, Inc.
Nephrotic Syndrome, Thromboembolic Disease
Causes and Prevention of Thromboembolic Disease in Nephrotic Syndrome
The study aims to describe the biochemical coagulation profile and investigate the effect of Low molecular weight heparin and Apixaban on this profile in patients with nephrotic syndrome.
- Trial name
- CAPTAIN (NCT04850378)
- Testing
- Dalteparin, Apixaban
- Where
- Denmark
- Volunteers
- 57 people
- Sponsor
- University of Aarhus
Hypertension
Sexual Dysfunction in Hypertensive Women
Several studies describe the existence of an association between sexual dysfunction and high blood pressure (hypertension), most often characterized by a decrease in the number of orgasms and the existence of dyspareunia.
- Trial name
- DYSFHO (NCT05156385)
- Testing
- Blood sample for the determination of antihypertensives or their metabolites., Questionnaire on sexual activity, Scale on hospital anxiety and depression
- Where
- France
- Volunteers
- 348 people
- Sponsor
- University Hospital, Toulouse
Hemodialysis, Kidney Disease, End-Stage
Cycling During Dialysis: A Feasibility and Safety Study
People who receive hemodialysis sit for about 4 hours, three times a week, and often feel tired and weak. Exercise can help, but many patients find it hard to exercise on their own.
- Conditions
- Hemodialysis, Kidney Disease, End-Stage, Fatigue
- Trial name
- NCT07905885
- Testing
- Supervised Intradialytic Cycling
- Volunteers
- 12 people
- Sponsor
- Sunnybrook Health Sciences Centre
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