Clinical trials: Urogenital
HIV (Human Immunodeficiency Virus)
Boosting Olfactory and Sensory Training Study (BOOST)
The goal of this study is to examine two types of olfactory interventions (conventional olfactory training vs scented marker training) in adults with HIV. The two research questions are: 1.
- Trial name
- BOOST (NCT07221123)
- Testing
- Conventional Smell Training Group, Scented Marker Group
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Alabama at Birmingham
Malignant Ovarian Clear Cell Tumor, Malignant Ovarian Serous Tumor
Activated T-cell Therapy, Low-Dose Aldesleukin, and Sargramostim in Treating Patients With Ovarian, Fallopian Tube, or Primary Peritoneal Cancer That is Stage III-IV, Refractory, or Recurrent
This phase I trial studies the side effects and best dose of activated T-cell therapy when given together with low-dose aldesleukin and sargramostim in treating patients with ovarian, fallopian tube, or primary peritoneal cancer…
- Conditions
- Malignant Ovarian Clear Cell Tumor, Malignant Ovarian Serous Tumor, Recurrent Fallopian Tube Carcinoma, Recurrent Ovarian Carcinoma
- Trial name
- NCT02470559
- Testing
- Aldesleukin, HER2Bi-Armed Activated T Cells, Laboratory Biomarker Analysis
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Detrusor Underactivity, Bladder Outlet Obstruction
DU and BOO in Women With and Without Symptoms of VD
Women with symptoms of voiding dysfunction may be associated with detrusor underactivity or bladder outlet obstruction. However, the prevalence of detrusor underactivity and bladder outlet obstruction remained obscure.
- Trial name
- NCT04981080
- Testing
- Urodynamic study
- Where
- Taiwan
- Volunteers
- 1,886 people
- Sponsor
- National Taiwan University Hospital
Breast Carcinoma, Endometrial Carcinoma
Caloric Restriction Before Surgery in Treating Patients With Endometrial, Prostate, or Breast Cancer
The purpose of this trial is to determine that sort term calorie restriction will affect tumor biology in biopsy proven breast, endometrial or prostate cancers, which will positively impact biomarkers including miR-21, an…
- Conditions
- Breast Carcinoma, Endometrial Carcinoma, Prostate Carcinosarcoma
- Trial name
- NCT02983279
- Testing
- Dietary Intervention, Counseling, Therapeutic
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Erectile Dysfunction
A Study to Evaluate Self-esteem and Relationships in Males With Erectile Dysfuntion
To determine the improvement in the self-esteem domain score of the Self-Esteem/Overall Relationship (SEAR) questionnaire and the improvement in erectile function (obtained from the Erectile Function [EF] domain of the…
- Trial name
- NCT00648596
- Testing
- sildenafil
- Where
- 66 sites in Finland, France and 6 more
- Volunteers
- 780 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Prostate Cancer
Saw Palmetto: Symptom Management for Men During Radiation Therapy
The aim of this study is to test whether Saw Palmetto, is useful in preventing or reducing the side effects for men undergoing radiation therapy for prostate cancer.
- Trial name
- NCT01585246
- Testing
- Saw Palmetto, soybean oil soft gel
- Where
- 6 sites in United States
- Volunteers
- 48 people
- Sponsor
- Michigan State University
Statin Induced Proteinuria
Statins and the Urinary Proteome
This study aims to investigate whether statines (rosuva- and pravastatin) induce tubular proteinuria.
- Trial name
- NCT00464503
- Testing
- Rosuvastatin-Crestor, Pravastatin-Pravasine
- Where
- Belgium
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
Non-Immune Hydrops Fetalis
Multicentric Prospective Study to Screen Inborn Errors of Metabolism in Non-immune Hydrops (NIH) Fetalis by Massively Parallel Sequencing
A fetal hydrops, also called a fetal anasarca, is the buildup of fluid in the serosa and / or fetal subcutaneous tissue. The diagnosis is made by ultrasound, possibly from the first trimester of pregnancy.
- Trial name
- ANAMETAB-PRO (NCT04308603)
- Testing
- NON-IMMUNE HYDROPS FETALIS diagnosis
- Where
- 17 sites in France
- Volunteers
- 71 people
- Sponsor
- Hospices Civils de Lyon
Premature, Premature Birth
Parental Participation on the Neonatal Ward - the neoPARTNER Study
Objective: To investigate the effect of FCR as part of the FICare principles during hospital stay, on parental stress at discharge in parents of preterm or ill infants admitted to the neonatal ward for >7 days as compared to…
- Conditions
- Premature, Premature Birth, Prematurity, Perinatal Problems
- Trial name
- neoPARTNER (NCT05343403)
- Testing
- Family Integrated Care
- Where
- 10 sites in Netherlands
- Volunteers
- 613 people
- Sponsor
- Onze Lieve Vrouwe Gasthuis
Nocturia, Benign Prostatic Hypertrophy (BPH)
Dose Response Study of VA106483 in Males With Nocturia and Benign Prostatic Hypertrophy (BPH)
The purpose of this study is to establish the dose response relationship of VA106483 and nocturnal urine volumes in a population of elderly male subjects with Benign Prostatic Hypertrophy (BPH) who are likely to present with…
- Trial name
- NCT01330927
- Testing
- VA106483
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Vantia Ltd
Prostatic Neoplasms
Role of Magnetic Resonance Imaging (MRI) Perfusion to Detect Disease in Prostate Carcinoma
This is a pilot study of 50 patients to establish whether there is a potential role for MRI perfusion in the detection of locally recurrent or persistent prostate carcinoma after previous treatment with radiotherapy.
- Trial name
- NCT00230386
- Testing
- MRI
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University Health Network, Toronto
Ovarian Neoplasms, Fallopian Tube Neoplasms
OVCA-NAC-P2: Study of Chemotherapy Followed by Cytoreductive Surgery for Ovarian, Tubal and Peritoneal Cancers: JCOG0206
A feasibility study of neoadjuvant chemotherapy (NAC) followed by interval cytoreductive surgery (ICS) and postoperative chemotherapy for stage III/IV mullerian carcinomas such as ovarian, tubal and peritoneal carcinomas.
- Conditions
- Ovarian Neoplasms, Fallopian Tube Neoplasms, Peritoneal Neoplasms
- Trial name
- NCT00112086
- Testing
- Neoadjuvant chemotherapy (Paclitaxel and Carboplatin)
- Where
- Japan
- Volunteers
- 56 people
- Sponsor
- Japan Clinical Oncology Group
Renal Impairment
A Phase I Study to Assess the Pharmacokinetics of Olorofim in Subjects With Renal Impairment
A single oral dose study to investigate the PK and safety of olorofim in subjects with severe renal impairment compared to subjects with normal renal function.
- Trial name
- NCT05200286
- Testing
- Olorofim
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- F2G Biotech GmbH
Prostate Cancer, Castrate Resistant Prostate Cancer
Sipuleucel-T and Ipilimumab for Advanced Prostate Cancer
This is a clinical trial designed to quantify the immune response and determine the tolerability and side effects of sipuleucel-T when given in combination with ipilimumab for patients with advanced prostate cancer.
- Trial name
- NCT01832870
- Testing
- sipuleucel-T, ipilimumab
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Prostate Oncology Specialists, Inc.
Benign Prostatic Hyperplasia
A Study of Tadalafil (LY450190) in Participants With Lower Urinary Tract Symptoms (LUTS) Suggestive of Benign Prostatic Hyperplasia LUTS (BPH-LUTS).
The main purpose of this study is to evaluate the safety and efficacy of the study drug known as tadalafil in participants with benign prostatic hyperplasia who are being treated with an alpha1 blocker.
- Trial name
- NCT02431754
- Testing
- Tadalafil, Alpha1 Blocker
- Where
- 9 sites in Japan
- Volunteers
- 171 people
- Sponsor
- Eli Lilly and Company
Spinal Cord Injury, Urinary Tract Infections
Adjuntive Probiotic Therapy in Treating Urinary Tract Infections in Spinal Cord Injury
We hypothesize that probiotic Lactobacillus can augment antibiotic treatment of symptomatic urinary tract infection (UTI) in spinal cord injured patients, and also increase the time to the next episode of UTI.
- Trial name
- NCT00594594
- Testing
- Probiotic Lactobacillus GR-1 and RC-14
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Healthy Men Age 50 Who Are Considering PSA Screening
Decision Support Interventions (DESI) for Prostate Cancer Screening - Study 1
In this study we will compare 3 strategies for systematic delivery of prostate cancer screening decision support interventions (DESI) to usual care and examine their impact on screening decisions and subsequent healthcare…
- Trial name
- NCT01241656
- Testing
- DESI for home viewing, DESI for viewing at Shared Medical Appointment, Option of SMA and DESI or DESI only
- Where
- 2 sites in United States
- Volunteers
- 2,521 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Diabetes, Gestational
Acute Effects of an Aquatic Physical Exercise on Glycemic Control of Gestational Diabetes
Gestational diabetes mellitus (GDM) is increasing worldwide and has been associated with adverse perinatal outcomes and high risk for chronic disease both for the mother and for the child.
- Trial name
- NCT02931656
- Testing
- Aquatic exercise
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute
Acute Kidney Injury (AKI), Postnatal AKI
NIRS Monitoring in the NICU and AKI
The primary objective of this study is to describe the pattern of renal tissue oxygen saturation (SrSO2) using near-infrared spectroscopy (NIRS) in premature infants <30 weeks gestational age.
- Trial name
- NCT07222722
- Testing
- NIRS Monitoring
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
HIV/AIDS, Sexual Behavior
Reducing HIV Risk in Urban Women: Soap Opera Videos on Video-Capable Cell Phones
Background: Love, Sex, and Choices (LSC) is a soap opera video series created to reduce HIV sex risk in women. Methods: LSC was compared to text messages in a randomized trial in 238 high-risk mostly Black young urban women.
- Conditions
- HIV/AIDS, Sexual Behavior, Woman's Role, Risk Behavior
- Trial name
- NCT03330522
- Testing
- Love, Sex, & Choices video series, Messages in text
- Where
- United States
- Volunteers
- 295 people
- Sponsor
- Northeastern University
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