Clinical trials: Urogenital Pathology
Ovarian Cancer, Neoplasm, Ovarian
Efficacy and Safety of Involving Field Radiotherapy in the Oligo-lesions(Metastasis/Recurrent/Refractory) of Ovarian Cancer
In this study, The researchers sought to explore the efficacy and safety of involving field radiotherapy in the oligo-metastatic/recurrent/refractory ovarian cancer patients among different groups which include drug therapy…
- Conditions
- Ovarian Cancer, Neoplasm, Ovarian, Ovarian Neoplasm, Ovary Neoplasms
- Trial name
- NCT05059782
- Testing
- chemotherapy, targeted therapeutics, immunotherapy, IFRT, IMRT or SBRT
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Xi'an Jiaotong University
Urinary Incontinence, Urge
Axonics SacRal NeuromodulaTIon System for Urinary Urgency Incontinence TreatmeNt
The ARTISAN-SNM study is designed to evaluate the safety and effectiveness of the Axonics Sacral Neuromodulation System as an aid in the treatment of the symptoms of urinary urgency incontinence (UUI) in patients who have failed…
- Trial name
- ARTISAN-SNM (NCT03327948)
- Testing
- Axonics Sacral Neuromodulation System (SNM) System
- Where
- 4 sites in United States, Netherlands and 1 more
- Volunteers
- 129 people
- Sponsor
- Axonics, Inc.
Chronic Kidney Disease
Optimal Titration Regimen for SBR759 in Lowering Serum Phosphate Levels in Asian Chronic Kidney Disease Patients on Hemodialysis
This study will determine the titration regimen for SBR759 compared to sevelamer HCl in lowering serum phosphate levels in Asian Chronic Kidney Disease patients on hemodialysis
- Trial name
- SBR759 (NCT00704678)
- Testing
- SBR759, Sevelamer HCl
- Where
- 15 sites in Japan, Taiwan
- Volunteers
- 203 people
- Sponsor
- Novartis Pharmaceuticals
Fatigue; Hemodialysis; Chronic Kidney Disease; Quality of Life
Effectiveness of Slow Back Stroke Massage and Murrotal Quran on Fatigue and Quality of Life of Patients Undergoing Haemodialysis
The study aimed to investigate the effectiveness of slow back stroke massage and murrotal Quran on fatigue and quality of life on patients undergoing hemodialysis.
- Trial name
- EMQ (NCT05183815)
- Testing
- slow stroke massage and murrotal quran
- Volunteers
- 30 people
- Sponsor
- Universitas Muhammadiyah Yogyakarta
Rectovaginal Fistula, Anovaginal Fistula
Feasibility and Safety of Additional Injection of Autologous Platelet-rich Stroma to Surgical Treatment of Rectovaginal Fistulas
Is the addition of platelet-rich stroma (PRS) injection, a form of autologous call therapy, to surgical treatment for rectovaginal fistula feasible and safe? The primary endpoints of this study are feasibility and safety until 12…
- Trial name
- PRS-RVF (NCT06798935)
- Testing
- autologous platelet-rich stroma
- Where
- Netherlands
- Volunteers
- 21 people
- Sponsor
- Erasmus Medical Center
Chronic Kidney Disease, Diabetic Kidney Disease
A Trial to Learn More About How BAY2327949 Works and How Safe it is in Patients Whose Kidneys Are Damaged Due to High Blood Sugar Levels or High Blood Pressures, and With a Further Disease of the Heart or the Blood Vessels.
In people with type 2 diabetes (T2D), the body makes insulin, but cannot use it well. This results in high blood sugar levels causing damage to the blood vessels inside the kidneys.
- Trial name
- ASSESS-CKD (NCT04661917)
- Testing
- BAY2327949
- Where
- 36 sites in Austria, Denmark and 5 more
- Sponsor
- Bayer
End-Stage Kidney Disease
Biological Determinants of Peritoneal Dialysis
Peritoneal Dialysis (PD) is a technique for treating kidney failure where fluid is instilled into the body's peritoneal cavity. Fluid and solutes travel across the peritoneal membrane, and the function of this membrane is…
- Trial name
- Bio-PD (NCT02694068)
- Testing
- Peritoneal Equilibrium Test, 4 hour dwell of 2.5/4.25% dextrose solution
- Where
- United States
- Volunteers
- 4,865 people
- Sponsor
- University of Washington
Chronic Kidney Diseases, Renal Disease
Pain Relief Intervention of Meditation in Renal Disease (PRIMER)
Kidney Disease subjects will be recruited to take part of a mindfulness-based stress reduction intervention for 8-10 sessions. All subjects will complete a baseline interview, one follow-up at 3 months and the close out interview…
- Conditions
- Chronic Kidney Diseases, Renal Disease, Chronic Kidney Failure, End Stage Renal Disease
- Trial name
- PRIMER (NCT03161197)
- Testing
- Mindfulness-Based Stress Reduction
- Volunteers
- 24 people
- Sponsor
- Weill Medical College of Cornell University
Urinary Bladder, Neurogenic
Urodynamic and Clinical Efficacy of Mirabegron for Neurogenic Bladder Patients
The proposed study is a randomized, double blind placebo controlled multicenter study to determine the effectiveness of mirabegron in the treatment of neurogenic bladder dysfunction.
- Trial name
- NCT02044510
- Testing
- Mirabegron
- Where
- 5 sites in Canada
- Volunteers
- 32 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Kidney Calculi
Ureteroscopy Combined With Negative Pressure Sheath Treatment of Kidney Stones
The removal rate, complication risk and operation time of ureteral soft scope combined with negative pressure suction sheath therapy for patients with high-load kidney stones (2-3cm) are still controversial.
- Trial name
- NCT06938113
- Where
- China
- Volunteers
- 115 people
- Sponsor
- Peking University First Hospital
Urinary Stress Incontinence
Urinary Incontinence and Other Pelvic Floor Dysfunctions in Trail Runners
The pelvic floor is a crucial complex for many bodily functions, supporting the pelvic organs and contributing to urinary and anal continence, as well as sexual function.
- Trial name
- IU-TRAIL (NCT06469320)
- Testing
- Online questionnaire
- Where
- Reunion
- Volunteers
- 1,500 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Overactive Bladder
Overactive Bladder (OAB) Voiding Diary and Urodynamics Correlation Study
This is a prospective cohort study study with the primary aim of identifying the strongest correlating parameters between voiding diaries and UDS studies most predictive for each type of urologic condition.
- Trial name
- NCT03473782
- Testing
- Voiding Diary, Urodynamics Correlation Study
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- NYU Langone Health
Chronic Kidney Diseases, Dialysis
Carriage Clearance of Emerging Highly Resistant Bacteria in Chronic Dialysis Patients
The propias, and more recently the update of the recommendations relating to the control of the spread of bacteria highly resistant to emerging antibiotics issued by the High Council of Public Health (December 2019), recommend…
- Trial name
- DIACOBHR (NCT04699682)
- Testing
- Control, BHR Case
- Where
- 5 sites in France
- Volunteers
- 600 people
- Sponsor
- Fondation Hôpital Saint-Joseph
End Stage Renal Disease
Confirmatory Study to Assess the V Needle in End-Stage Renal Disease Patients During In-Clinic Hemodialysis
This study is a prospective, multi-center, single-arm study with subjects acting as their own control designed to confirm the safety, performance, and usability of the V Needle, a new safety needle for use during in-clinic…
- Trial name
- Clinic-SAVER (NCT05493423)
- Testing
- V Needle AV Fistula Set
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Hemotek Medical Inc
Pelvic Floor Disorders, Sport Injury
Quality and Behavior of Pelvic Floor in Runner Women
The main objective is to analyze the relationship between the PF muscles and the other variables along the different tasks of daily life and during the race.
- Conditions
- Pelvic Floor Disorders, Sport Injury, Stress Urinary Incontinence
- Trial name
- NCT03934996
- Testing
- Runners with educational training
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Malaga
Hypertension, Renal Insufficiency, Chronic
Evaluation of an Electronic CKD Clinical Decision Support System (CDSS) in Clinical Care
The investigators propose a three-arm, pragmatic, cluster-randomized clinical trial based in primary care. Participating Primary Care Providers (PCPs) will be randomized to usual care or one of two intervention arms.
- Trial name
- CDSSR18 (NCT02925962)
- Testing
- Clinical Decision Support System (CDSS), Clinic Decision Sup System + Pharmacist
- Where
- United States
- Volunteers
- 542 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Post Partum Hemorrhage, Blood Loss
Estimating Blood Loss Using TritonTM in Vaginal Deliveries: A Validation Trial
This study will be a prospective cohort study. Patients who meet criteria for inclusion in the study will be approached for participation at same day of admission.
- Conditions
- Post Partum Hemorrhage, Blood Loss, Vaginal Bleeding, Vaginal Delivery
- Trial name
- ELUSIVE (NCT04277962)
- Testing
- Triton L and D system for estimation of blood loss at time of vaginal delivery
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Neurogenic Bladder, Bladder Dysfunction
Vascularized Composite Bladder Allograft Transplantation
This phase 0 trial tests the feasibility, functionality, and sustainability of vascularized composite bladder allograft transplantation in treating patients with terminal bladder pathology.
- Conditions
- Neurogenic Bladder, Bladder Dysfunction, Immunosuppression
- Trial name
- NCT05462561
- Testing
- Quality-of-Life Assessment, Robotic Vascularized Composite Bladder Allograft Transplantation
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Southern California
HIV-1-infection, Inflammation
The MISTRAL Study: Gut Microbiome Correlates of Serious AIDS and Non-AIDS Events
MISTRAL (Microbiome-based stratification of individuals at risk of HIV-1 acquisition, chronic clinical complications, antimicrobial drug resistance, and unresponsiveness to therapeutic HIV-1 vaccination) is a 5-year EU Horizon…
- Conditions
- HIV-1-infection, Inflammation, AIDS
- Trial name
- MISTRAL (NCT05421286)
- Where
- 22 sites in Belgium, Croatia and 9 more
- Volunteers
- 991 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Hepatitis C Virus (HCV)
A Study to Evaluate the Efficacy and Safety of Glecaprevir/Pibrentasvir (ABT-493/ABT-530) in Treatment-Naive and Treatment-Experienced, Non-Cirrhotic Asian Adults With Chronic Hepatitis C Virus Genotype (GT) 1 to GT6 Infection With or Without Human Immunodeficiency Virus Co-Infection
This study will evaluate the efficacy and safety of glecaprevir/pibrentasvir (ABT-493/ABT-530) in non-cirrhotic chronic hepatitis C virus (HCV) genotype (GT)1 to GT6-infected Asian participants with or without human…
- Trial name
- VOYAGE-1 (NCT03222583)
- Testing
- Glecaprevir/Pibrentasvir
- Where
- 48 sites in China, Singapore and 1 more
- Volunteers
- 546 people
- Sponsor
- AbbVie
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