Clinical trials: Urogenital Pathology
Ckd-Mbd
Relationship Between Cardiopulmonary Exercise Testing and Ca-P in Chronic Kidney Disease (CKD)
Reductions in exercise capacity associated with exercise intolerance augment cardiovascular disease risk and predict mortality in chronic kidney disease.
- Trial name
- NCT04013139
- Testing
- CPET
- Where
- Iran
- Volunteers
- 200 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Postpartum Hemorrhage
rhuFVIIa in Post-partum Hemorrhage
The aim of this clinical research project is to evaluate the use of the recombinant human activated factor VII (rhFVIIa), given as a salvage therapy, in women with a dramatic postpartum hemorrhage still ongoing after all the…
- Trial name
- NCT00370877
- Testing
- rFVIIa, Standard Care
- Where
- 8 sites in France, Switzerland
- Volunteers
- 84 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Infections, Papillomavirus
Evaluation of Immunogenicity and Safety of Two 2-dose Human Papillomavirus (HPV) Vaccine Schedules in 9-14 Year Old Girls
This study has been designed to evaluate the immunogenicity and safety of GSK Biologicals' HPV-16/18 vaccine when administered according to alternative 2-dose schedules (0,6 months and 0,12 months) in healthy 9-14 year old…
- Trial name
- NCT01381575
- Testing
- GSK Biologicals' HPV vaccine 580299
- Where
- 33 sites in Canada, Germany and 3 more
- Volunteers
- 1,447 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Urinary Incontinence
Physiotherapy Management in Women With Urinary Incontinence
Main objective: The primary aim of the study is to assess whether the author's exercise programme has an effect on reducing urinary incontinence and pelvic floor dysfunction after childbirth, considering vacuum extractor, forceps…
- Trial name
- NCT06581601
- Testing
- physiotherapy, exercises
- Where
- Poland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Preterm, Pain
Reducing Pain During Orogastric Tube Placement in Preterm
The aim of this study is to determine the effectiveness of 3 different methods (breast milk pacifier, sucrose pacifier and pacifier) in reducing pain caused by Orogastric Tube (OGT) insertion in preterm newborns by monitoring…
- Conditions
- Preterm, Pain, Nursing Caries
- Trial name
- NCT05430100
- Testing
- The effect of usıng breast mılk pacıfıer ın reducıng the paın that occurs durıng orogastrıc tube ınsertıon ın preterm newborns, The effect of usıng sucrose pacıfıer ın reducıng the paın that occurs durıng orogastrıc tube ınsertıon ın preterm newborns, The effect of usıng pacıfıer ın reducıng the paın that occurs durıng orogastrıc tube ınsertıon ın preterm newborns
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Chronic Kidney Disease
Combined Western and Traditional Chinese Medicine Daycare for CKD Patients
The annual report of USRDS shows than Taiwan has the highest prevalence of end-stage-renal-disease globally resulted in high prevalence dialysis rate.
- Trial name
- NCT02545036
- Testing
- Traditional Chinese Medicine (TCM) daycare model
- Where
- Taiwan
- Volunteers
- 58 people
- Sponsor
- China Medical University Hospital
Overactive Bladder
Hypnotherapy for Treatment of Overactive Bladder
The investigators purpose is to perform a pilot study evaluating the efficacy in hypnotherapy in treating women with Overactive Bladder Symptoms (urinary urgency symptoms and urinary frequency).
- Trial name
- NCT00793611
- Testing
- Behavioral therapy standard of care, hypnotherapy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Overactive Bladder
Mirabegron Combined With Behavioral Intervention for Overactive Bladder：a Prospective Multicenter Randomized Controlled Clinical Study
The purpose of this study was to assess the efficacy, safety and tolerability of Mirabegron and behavioral combination versus Mirabegron alone in the treatment of women with overactive bladder (OAB）.
- Trial name
- NCT05452434
- Testing
- mirabegron
- Volunteers
- 600 people
- Sponsor
- Peking Union Medical College Hospital
Advanced Solid Tumor, Locally Advanced Solid Tumor
A Study to Investigate Safety and Tolerability of TransCon IL-2 β/γ Alone or in Combination With Pembrolizumab and/or TransCon TLR7/8 Agonist or Other Anticancer Therapies in Adult Participants With Locally Advanced or Metastatic Solid Tumor Malignancies
TransCon IL-2 β/γ is an investigational drug being developed for treatment of locally advanced or metastatic solid tumors. This is a first-in-human, open-label, Phase 1/2, dose escalation and dose expansion study of TransCon IL-2…
- Conditions
- Advanced Solid Tumor, Locally Advanced Solid Tumor, Metastatic Solid Tumor, Platinum-resistant Ovarian Cancer
- Trial name
- IL Believe (NCT05081609)
- Testing
- TransCon IL-2 β/γ, Pembrolizumab, Chemotherapy drug
- Where
- 68 sites in United States, Australia and 8 more
- Volunteers
- 320 people
- Sponsor
- Ascendis Pharma Oncology Division A/S
Fibroid Uterus, Metrorrhagia
A Randomized Study Comparing Subtotal vs Total Hysterectomy Long Term Outcomes
The goal of this randomized clinical trial is to assess the outcomes of total laparoscopic hysterectomy vs subtotal laparoscopic hysterectomy + mini-laparotomy for uterine extraction for benign gynecological conditions in terms…
- Conditions
- Fibroid Uterus, Metrorrhagia, Adenomyosis, Benign Gynecologic Neoplasm
- Trial name
- STORY (NCT06802198)
- Testing
- total hysterectomy, subtotal hysterectomy
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Hyperandrogenism
Phase II Randomized Study of Leuprolide Vs Oral Contraceptive Therapy Vs Leuprolide and Oral Contraceptive Therapy for Ovarian Hyperandrogenism
OBJECTIVES: I. Evaluate the beneficial effects of leuprolide depot, oral contraceptive therapy, and leuprolide/oral contraceptive therapy in the management of patients with ovarian hyperandrogenism.
- Trial name
- NCT00004763
- Testing
- leuprolide, Ethinyl estradiol/norethindrone
- Volunteers
- 45 people
- Sponsor
- National Center for Research Resources (NCRR)
Fetal Growth Retardation
Vitamin D Versus Sildenafil Citrate in Fetal Growth Restriction
Fetal growth restriction, also named Intrauterine growth restriction is a prevalent disease in pregnancy , it is a descriptive term for a pathological process, and can be described as the process where a fetus who has a certain…
- Trial name
- NCT06565728
- Testing
- Vitamin D3 2000 UNT Oral Tablet
- Where
- Egypt
- Volunteers
- 99 people
- Sponsor
- Cairo University
Polycystic Ovarian Syndrome (PCOS)
This Study Aims to Evaluate Whether Milamend's Product Could Improve Hormone Balance in Women Who Suffer From Self-reported PCOS Symptoms.
The rationale for this study is to observe the impact of a consumer-grade commercially available product called Milamend Hormone Balance on quality of life and hormonal health in women with self-reported symptoms associated with…
- Trial name
- NCT07764328
- Testing
- A dietary supplement powder for women
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Mila Mend Inc.
Chronic Kidney Disease (Stages 3b-5)
Pistachio Consumption in Patients With Chronic Kidney Disease
Standard chronic kidney disease (CKD) guidelines frequently restrict nut intake due to concerns regarding their phosphorus and potassium content.
- Trial name
- NCT07815600
- Testing
- Pistachio, Control
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Menorrhagia Due to Benign Causes
Reframing Endometrial Physiology by Advanced Integrated Research
Heavy menstrual bleeding (HMB) affects 1 in 3 women and can significantly impact quality of life. Despite its prevalence, there is no accessible and accurate diagnostic test.
- Trial name
- REPAIR (NCT07557992)
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Prostate Cancer, Prostate Cancer (Diagnosis)
Study of the Epidemiological, Clinical, Diagnostic, and Therapeutic Characteristics of Prostate Cancers in Algeria
The goal of this observational study is to describe the demographic, epidemiological, clinical, and outcome characteristics of patients with prostate cancer.
- Conditions
- Prostate Cancer, Prostate Cancer (Diagnosis), Prostate Cancer (Post Prostatectomy), Prostate Cancer Patients Treated by Radiotherapy
- Trial name
- CLIQQC (NCT07484971)
- Where
- 24 sites in Algeria
- Volunteers
- 2,000 people
- Sponsor
- Société Algérienne de Formation et Recherche en Oncologie
Tonsillectomy
Tonsillectomy and Primitive IgA Nephropathy in Children: Strasbourg Cohort and Assessment Practices in Inter North East Region
Primitive kidney disease IgA, represented by Berger's disease and rheumatoid purpura nephropathy, are the first cause of kidney failure from chronic glomerulonephritis: changes in 20 years to end-stage renal failure is described…
- Trial name
- NCT02829164
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Strasbourg, France
Menorrhagia
The Assessment of Tranexamic Acid in Women With Menorrhagia Who Have Bleeding Disorders
Many women have heavy periods and this can be associated with low blood, tiredness and inability to carry out normal activities. Approximately 10-30% of these women will have an underlying bleeding disorder.
- Trial name
- NCT00904709
- Testing
- tranexamic acid
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- K. Sue Robinson
Heavy Menstrual Bleeding
Quality of Life in Premenopausal Women With Heavy Menstrual Bleeding
Heavy menstrual bleeding or menorrhagia, is a common problem on women's lives and can burden both patients and health care systems. HMB is defined as cyclic heavy vaginal bleeding.
- Trial name
- NCT03368898
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Chronic Kidney Disease
INCLUDE-CKD: INCLUsive Digital carE for Chronic Kidney Disease
This study will provide valuable insights into the demographics of MyRenalCare users, their digital adherence, and the overall impact of the app on health outcomes, healthcare costs, and environmental sustainability.
- Trial name
- INCLUDE-CKD (NCT07613593)
- Testing
- Non-Interventional Study
- Where
- United Kingdom
- Volunteers
- 1,000 people
- Sponsor
- Portsmouth Hospitals NHS Trust
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