Clinical trials: Using Nesiritide
Heart Failure
A Health Economic Evaluation of Using N-Terminal Pro Brain Natriuretic Peptide (NT-Pro BNP) in Acute Heart Failure
Cardiac biomarkers have dramatically impacted the way HF patients are evaluated and managed. In fact, the role of biomarkers has developed to better differentiate HF against other diseases and, to timely initiate and influence…
- Trial name
- NCT03669198
- Testing
- NT-Pro BNP
- Where
- Indonesia
- Volunteers
- 56 people
- Sponsor
- Heart Failure Biomarker Group
Preeclampsia, Maternal
A Comparison of BNP Levels Using the Nexfin Device in Healthy Pregnant and Preeclamptic Women
Primary Endpoint: Quantify the hemodynamic changes in preeclampsia using the non-invasive Nexfin device. Secondary Endpoint: Determine if measurable hemodynamic changes are statistically correlated with B-type natriuretic peptide…
- Conditions
- Preeclampsia, Maternal, Hypertension, Pregnancy
- Trial name
- NCT02527018
- Testing
- Sphygmomanometer
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Heart Failure, Congestive
A Safety Study Comparing Natrecor (Nesiritide) Versus Dobutamine Therapy for Worsening Congestive Heart Failure
The purpose of this study is to compare the effects on heart rate and ventricular arrhythmias (irregular heart beats) of two doses of Natrecor® (a recombinant form of the natural human peptide normally secreted by the heart in…
- Trial name
- NCT00270400
- Testing
- nesiritide
- Volunteers
- 255 people
- Sponsor
- Scios, Inc.
Heart Failure
RISK Stratification Using a Combination of Cardiac Troponin T and Brain Natriuretic Peptide in Patients Receiving CRT-D
The purpose of the study is to identify if the combined use of cardiac troponin enzyme (cTnT) and brain natriuretic peptide (BNP) can predict Heart Failure (HF)improvement and all-cause mortality in patients implanted with…
- Trial name
- RISK (NCT00453622)
- Testing
- Cardiac Resynchronization Therapy-Defibrillator
- Where
- United States
- Volunteers
- 222 people
- Sponsor
- Abbott Medical Devices
Dyspnea
Prehospital Triage of Patients With Severe Shortness of Breath Using Biomarkers
Breathlessness is a dangerous symptom. Preliminary data from national and regional Danish databases show, that patients with shortness of breath in the ambulance have a very high mortality.
- Trial name
- PreBNP (NCT02050282)
- Testing
- Supplementary NT-proBNP measurement
- Where
- 9 sites in Denmark
- Volunteers
- 712 people
- Sponsor
- University of Aarhus
Congestive Heart Failure, Mechanical Ventilation
Nesiritide for Ventilated Congestive Heart Failure
The congestive heart failure is a common disease among patients who receive cardiac surgery and may lead to prolonged ventilation support. Nesiritide was a potential therapy for congestive heart failure.
- Conditions
- Congestive Heart Failure, Mechanical Ventilation, Using Nesiritide, Venous Return
- Trial name
- HENCHF (NCT04455477)
- Testing
- Nesiritide
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Zhongshan Hospital
Coronary Artery Disease
Effect of BNP (Brain Natriuretic Peptides) on Endothelial Dysfunction Induced by Coronary Angioplasty
Patients receiving BNP or nitroglycerin (IV) during the angioplasty procedure. 24 h after the procedure, vascular reactivity will be re-examined using the brachial artery flow-mediated dilatation study.
- Trial name
- NCT00262574
- Testing
- Nesiritide,
- Where
- Israel
- Volunteers
- 500 people
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Breast Neoplasms, Heart Failure
Cardiotoxicity of Adjuvant Trastuzumab
Trastuzumab (Herceptin®) increases the chances of cure in patients with Her-2 overexpressing early breast cancer. Unfortunately, both the chemotherapy drugs used in this setting (anthracyclines) and trastuzumab are known to cause…
- Trial name
- CATS (NCT00858039)
- Where
- 15 sites in Australia
- Volunteers
- 220 people
- Sponsor
- Royal Prince Alfred Hospital, Sydney, Australia