Clinical trials: Usual Care
Hot Flashes, Prostate Cancer
Acupuncture Versus Sham Acupuncture or Usual Care for Antiandrogen-Induced Hot fLashes in Prostate Cancer (AVAIL)
Hot flashes are a common and debilitating symptom among prostate cancer patients undergoing androgen deprivation therapy (ADT). Strong evidence from multiple rigorously designed studies indicated that venlafaxine provides partial…
- Conditions
- Hot Flashes, Prostate Cancer, Acupuncture
- Trial name
- AVAIL (NCT05069467)
- Testing
- Acupuncture
- Where
- 3 sites in China
- Volunteers
- 120 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
ARDS, Respiratory Effort
Comparison of Guiding Sedation Level by Respiratory Effort Versus Usual Care in Mechanically Ventilated Patients: A Randomized Controlled Trial (EFFORT-GUIDE Trial 2)
The objective of this research is to utilize respiratory effort parameters as a tool to assist in adjusting sedative drug levels for patients undergoing mechanical ventilation in the intensive care unit, in comparison to the…
- Conditions
- ARDS, Respiratory Effort, Mechanical Ventilation Complication, Sedation
- Trial name
- NCT06242236
- Testing
- The respiratory effort parameters guide sedative dosage.
- Where
- Thailand
- Volunteers
- 156 people
- Sponsor
- Ramathibodi Hospital
Cancer
Effectiveness of Blended and Unguided Delivery of Mindfulness-based Cognitive Therapy for Cancer Patients
Rationale: Approximately one in three cancer patients and survivors experience significant psychological distress. Previous research has shown that mindfulness-based interventions such as mindfulness-based cognitive therapy…
- Trial name
- BUDDY (NCT05336916)
- Testing
- Buddy
- Where
- Netherlands
- Volunteers
- 254 people
- Sponsor
- Radboud University Medical Center
Asthma
Study In Asthma Control
This study will compare patients treated with a marketed medication and those who continue with their usual care to assess the proportion of patients achieving well controlled asthma after 24 weeks.
- Trial name
- NCT00273026
- Testing
- salmeterol xinafoate/fluticasone propionate
- Where
- 132 sites in Canada
- Volunteers
- 680 people
- Sponsor
- GlaxoSmithKline
Stroke
Finding Atrial Fibrillation in Stroke - Evaluation of Enhanced and Prolonged Holter Monitoring
The purpose of this study is to assess whether repeated enhanced and prolonged ECG monitoring after ischemic stroke results in a higher detection of atrial fibrillation (/flutter) compared to usual care (at least 24 hour of…
- Trial name
- NCT01855035
- Testing
- prolonged ECG monitoring, standard care
- Where
- 4 sites in Germany
- Volunteers
- 402 people
- Sponsor
- Institut fuer anwendungsorientierte Forschung und klinische Studien GmbH
Arthritis, Psoriatic, Psoriasis
Study Evaluating the Safety and Efficacy of Etanercept in Patients With Psoriatic Arthritis Treated by Dermatologists
The purpose of this study is to evaluate the safety profile and the effectiveness of etanercept under usual care settings in patients with PsA treated by dermatologists.
- Conditions
- Arthritis, Psoriatic, Psoriasis, Skin Diseases, Papulosquamous
- Trial name
- NCT00293709
- Testing
- etanercept
- Where
- Germany
- Volunteers
- 129 people
- Sponsor
- Pfizer
Impoverished Population
Patient-Directed Lifestyle Change and Health Promotion Program or Usual Care in Low-Income, Uninsured Participants in Los Angeles County, California
RATIONALE: Clinic-based health programs may be effective in improving the diets and physical activity levels of low-income, uninsured participants in Los Angeles County, California.
- Trial name
- NCT00521209
- Testing
- Self-Care Stimulating Disease Prevention Program (SCSDPP), Stand procedures, no intervention
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Jonsson Comprehensive Cancer Center
Type II Diabetes
Effectiveness of an mHealth Mobile App
Type II diabetes is a serious challenge for Pakistan. Not using medications properly increases healthcare costs and diabetes-related deaths.
- Trial name
- mHealth (NCT06387433)
- Testing
- mobile app use
- Where
- Pakistan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Asthma
Asthma Care With Alvesco® (Ciclesonide) in Primary Care in Adults - The ACCEPT-study (BY9010/CA-102)
The purpose of this study is to investigate the effectiveness of Alvesco® (Ciclesonide) compared with usual asthma care in the primary care setting.
- Trial name
- NCT00404547
- Testing
- Ciclesonide, Usual Care Inhaled Glucocorticosteroids
- Where
- 186 sites in Canada
- Volunteers
- 1,121 people
- Sponsor
- AstraZeneca
Depression
Cluster Randomized Trial of Stepped Care Intervention vs. Treatment as Usual for Patients With Depression
The main aim of the project is the implementation and evaluation of a stepped care model (SCM) for patients with depression with 6 treatment options of varying intensity and setting, including innovative technologies (e-mental…
- Trial name
- SCM (NCT01731717)
- Testing
- Active monitoring, Bibliotherapy, Online self-help
- Where
- Germany
- Volunteers
- 737 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Bronchiectasis Adult, Lung Infection
The Effect of Long Term Therapy With High Flow Humidification Compared to Usual Care in Patients With Bronchiectasis (BX)
The study is intended to understand the benefit of Long Term Home care Therapy with nasal High flow in Bronchiectasis patients at home.
- Conditions
- Bronchiectasis Adult, Lung Infection, Quality of Life, Humidifier Lung
- Trial name
- BX (NCT04142827)
- Testing
- High Flow Humidification
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- Dr. Giuseppe Fiorentino
Traumatic Intracranial Hemorrhage
Restart TICrH AP Pilot Trial
A Prospective Randomized Open-Label Blinded Endpoint (PROBE) Pilot Trial of restarting antiplatelet therapy at 1 week versus 3 weeks after traumatic intracranial hemorrhage with a primary composite endpoint of major bleeding and…
- Trial name
- NCT05000060
- Testing
- Timing/1 week, Timing/3 weeks
- Volunteers
- 100 people
- Sponsor
- University of Texas at Austin
COPD
Palliative Care Health Literacy Education and QOL Compared to Usual Care
The goal of this pilot randomized controlled trial is to compare health literacy (HL) and quality of life (QOL) among older adults with chronic obstructive pulmonary disease (COPD) who completed a series of standardized…
- Trial name
- PACED (NCT06089499)
- Testing
- Get Palliative Care: four educational learning module videos
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Missouri, Kansas City
Anemia; Sickle-Cell, With Crisis, Acute Pain
Ketamine Infusion for Sickle Cell Pain Crisis
The purpose of this study is to prospectively study the efficacy of low dose ketamine infusions in treating patients who are admitted to the hospital with a sickle cell pain crisis.
- Trial name
- NCT04005209
- Testing
- Ketamine, Pain management
- Where
- United States
- Sponsor
- Duke University
Schizophrenia and Disorders With Psychotic Features
Specialized Treatment Early in Psychosis (STEP)
The purpose of this study is to understand the effectiveness of a specialized package of phase-specific treatments for individuals in the midst of their first episode of psychosis.
- Trial name
- STEP (NCT00309452)
- Testing
- Cognitive Behavioral Group Therapy, Cognitive remediation, Medications
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Yale University
Palliative Care, Intensive Care Unit
Critical Care and Palliative Care Medicine Together in the ICU
Will earlier palliative care medicine consultation in the ICU result in decreased length of stay in the ICU and hospital, as well as, increased patient and family satisfaction.
- Conditions
- Palliative Care, Intensive Care Unit, Hospice
- Trial name
- NCT03520023
- Testing
- Palliative Care Consult
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Mayo Clinic
Cardiorespiratory Failure
Harnessing Alternative Resources to Aid Kenyans With Acute Illness
Kenya does not have enough experts to perform heart scans in patients who are very sick and in need of urgent intervention. The purpose of this research is to find out whether training Kenyan nurses to perform basic heart scans…
- Trial name
- HARAKA-2 (NCT04344418)
- Testing
- Nurse-performed Focused cardiac ultrasound (FoCUS), Usual care
- Volunteers
- 732 people
- Sponsor
- Aga Khan University
Muscular Atrophy, Spinal
A Study of the Safety of Nusinersen (Spinraza®) and Its Effects on Motor Function in Koreans Living With SMA Treated During Their Usual Medical Care
In this study, researchers will learn more about the effects of nusinersen, also known as Spinraza®, in Korean participants with spinal muscular atrophy, also known as SMA.
- Trial name
- STANDARD (NCT04317794)
- Testing
- Nusinersen Sodium Injection
- Where
- 16 sites in South Korea
- Volunteers
- 74 people
- Sponsor
- Biogen
Acute Myeloid Leukemia
A Patient-Centered Communication Tool (UR-GOAL) Versus Usual Care for Older Patients With Acute Myeloid Leukemia, Their Caregivers, and Their Oncologists
The objective of this study is to evaluate the preliminary efficacy of the UR-GOAL tool in improving shared decision making and communication between older patients with AML and their oncologists in a pilot randomized trial.
- Trial name
- UR-GOAL 2 (NCT05335369)
- Testing
- UR-GOAL
- Where
- United States
- Volunteers
- 161 people
- Sponsor
- University of Rochester
Hypermobility, Joint, Hypermobility Syndrome
Exercise in Patients With Hypermobile Joints and Knee Pain
Pain associated with knee joint hypermobility is common in the adult population, but evidence on treatment is sparse. This study investigates if high-load resistance training is superior to usual care in improving…
- Conditions
- Hypermobility, Joint, Hypermobility Syndrome, Knee Discomfort
- Trial name
- HIPEr-Knee (NCT06277401)
- Testing
- Neuromuscular training for the knee, High-load strength training for the knee
- Where
- 2 sites in Denmark
- Volunteers
- 80 people
- Sponsor
- University of Southern Denmark