Clinical trials: Uterine Artery Embolisation
Leiomyomas
Diffusion -and Perfusion Weighted MRI for Response Prediction of Symptomatic Leiomyomas Following Uterine Artery Embolization
It is known that volumetric response of leiomyomas following uterine artery embolization correlates well with patients clinical outcome.
- Trial name
- NCT01514617
- Testing
- Diffusion -and perfusion weighted MRI including iv contrast agent injection
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Leiomyoma
Dexamethasone for Post Uterine Artery Embolization Pain
The purpose of this research is to investigate if administration steroids (anti-inflammatory medication) via the uterine arteries during uterine fibroid embolization (A non surgical procedure for treating uterine fibroids by…
- Trial name
- Dex-Fib (NCT04655144)
- Testing
- Dexamethasone, Saline
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Miami
Adenomyosis
Ttt of Adenomyosis
to evaluate use of Dienogest versus uterine arteries embolization in treatment of Adenomyosis-associated symptoms as dysmenorrhea, heavy menstrual bleeding and bulk-related symptoms
- Trial name
- NCT06719934
- Testing
- Dienogest 2 mg orally, UAE
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Al-Azhar University
Exposure to Magnetic Field, Uterine Leiomyoma
Predictive Factors of Pelvic Magnetic Resonance in the Response of Arterial Embolization of Uterine Leiomyoma
The purpose of this study is to determine predictive factors in the pelvic magnetic resonance in the response of arterial embolization of uterine leiomyoma.
- Trial name
- NCT01468402
- Testing
- Magnetic Resonance Image
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Hospital Israelita Albert Einstein
Uterine Fibroids
Post-Operative Pain Management in Patients Undergoing Uterine Artery Embolisation for Symptomatic Leiomyomata
This project seeks to evaluate the effectiveness of a new post-operative pain relief program for women who have undergone uterine artery embolisation (UAE).
- Trial name
- NCT00163930
- Where
- Australia
- Sponsor
- Bayside Health
Abnormal Uterine Bleeding Due to Adenomyosis (Disorder)
Radiofrequency Endometrial Ablation or Uterine Artery Embolization for Treatment of Adenomyosis-related Abnormal Uterine Bleeding
The present study aims to compare the efficacy (menstrual blood loss, pain, quality of life) and the safety (complications, recovery) of each conservative intervention (RFA, UAE) versus hysterectomy for the treatment of…
- Trial name
- ADENOTREAT (NCT07195305)
- Testing
- Radiofrequency endometrial ablation, Uterine artery embolization, Hysterectomy
- Where
- 4 sites in France
- Volunteers
- 230 people
- Sponsor
- University Hospital, Bordeaux
Uterine Fibroid
Satisfaction of Patients With Trans-Arterial Radial Access: Quality of Life in Uterine Fibroid Embolization Trial
Randomized trial comparing uterine fibroid embolization patient satisfaction and quality of life with femoral versus radial arterial access
- Trial name
- SPARQLE (NCT03021720)
- Testing
- Arterial access
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- Mount Sinai Hospital, Canada
Uterine Fibroid
Bearing nsPVA Embolization for Uterine Artery Embolization (BETTER-UAE)
This is a prospective, multicenter, observational, post-market clinical follow-up study in subjects treated with Bearing nsPVA Embolization Particles for uterine fibroid embolization.
- Trial name
- BETTER-UAE (NCT06153667)
- Testing
- Bearing nsPVA
- Where
- 4 sites in United States, Australia and 1 more
- Volunteers
- 100 people
- Sponsor
- Merit Medical Systems, Inc.
Uterine Leiomyoma
Uterine Artery Embolization With Microspheres in Patients With Leiomyoma.
To evaluate the therapeutic response to uterine artery embolization in 30 patients with leiomyoma using the microspheres Embosoft (Embosoft® - Scitech Medical).
- Trial name
- EMBOSOFT I (NCT03535610)
- Testing
- Uterine Embolization
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Scitech Produtos Medicos SA
Leiomyoma
Fertility After Myomectomy Versus Uterine Artery Embolization for Symptomatic Uterine Fibroids
Purpose of this study: To establish the superiority of myomectomy versus Uterine Artery Embolization, in women with multiple symptomatic fibroids and no other infertility factor, seeking to conceive.
- Trial name
- Lune2 (NCT02577055)
- Testing
- myomectomy, embolisation
- Where
- France
- Volunteers
- 9 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Menorrhagia, Leiomyoma
Emmy Trial: Uterine Artery Embolization (UAE) Versus Hysterectomy for Uterine Fibroids
The Emmy trial is set up to evaluate the safety and efficacy of uterine artery embolization (UAE) in comparison to hysterectomy for the treatment of symptomatic uterine fibroids.
- Conditions
- Menorrhagia, Leiomyoma, Uterine Neoplasms
- Trial name
- NCT00100191
- Testing
- uterine artery embolization, hysterectomy
- Where
- 2 sites in Netherlands
- Volunteers
- 120 people
- Sponsor
- ZonMw: The Netherlands Organisation for Health Research and Development
Myoma
Myoma Microvascularization Analysis Using Sonovue Before and After Uterine Artery Embolization
Contrast-enhanced ultrasound is supposed to improve the detection of myomas as well as improve the follow-up after specific treatments like embolization.
- Trial name
- NCT00351494
- Testing
- contrast enhanced ultrasonography, embolization
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Tours
Uterine Fibroids, Arterial Embolization
Uterine Fibroid Embolization- Long Term Follow up and Technical Perspectives
The purpose of this prospective non-randomised study is to examine whether two different microspheres (Bead-Block and Embosphere) are equally effective in the treatment of the uterine fibroid controlled with contrast-enhanced MR…
- Trial name
- NCT01852734
- Testing
- embolizations ,uterine fibroid, embolizations
- Where
- 2 sites in Denmark
- Volunteers
- 52 people
- Sponsor
- Odense University Hospital
Urinary Tract Infection, Leiomyoma
Lower Urinary Tract Infection (UTI) Evaluation in Women With Uterine Leiomyomata
To the investigators knowledge there is no research data published to date regarding the lower urinary tract symptoms in women with leiomyomas. The primary aims of this study are: 1.
- Trial name
- LOTUS (NCT01123603)
- Where
- United States
- Volunteers
- 860 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Postpartum Hemorrhage
rhuFVIIa in Post-partum Hemorrhage
The aim of this clinical research project is to evaluate the use of the recombinant human activated factor VII (rhFVIIa), given as a salvage therapy, in women with a dramatic postpartum hemorrhage still ongoing after all the…
- Trial name
- NCT00370877
- Testing
- rFVIIa, Standard Care
- Where
- 8 sites in France, Switzerland
- Volunteers
- 84 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Uterine Leiomyomas
Intra-arterial Lidocaine for Pain Control Post Uterine Fibroid Embolization
Uterine artery embolization (UAE) is a minimally invasive treatment for women with symptomatic fibroids. It is similar to hysterectomy in term of satisfaction and symptoms improvement, with fewer complications and at lower cost.
- Trial name
- NCT02293447
- Testing
- Lidocaine per-embolization, Lidocaine post-embolization
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University Health Network, Toronto
Heavy Menstrual Bleeding, Fibroid Uterus
Myomectomy vs Uterine Artery Embolization vs GnRh Antagonist for AUB-L
This is a prospective cohort study comparing the novel FDA-approved oral GnRH antagonist ORIAHNN (elagolix, estradiol, and norethindrone acetate capsules; elagolix capsules) to uterine artery embolization (UAE) or myomectomy…
- Trial name
- Magical (NCT04856306)
- Testing
- Groups 1 and 2 myomectomy and uterine artery embolization, respectively, are surgical/procedure, Elagolix Oral Product
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Leiomyoma
Comparison of Pain of Two Different Methods in Uterine Artery Embolization
The primary purpose of this study is to compare pain after uterine artery embolization using non-spherical polyvinyl alcohol particles or tris-acryl gelatin microsphere in patients with symptomatic fibroids
- Trial name
- NCT03420248
- Testing
- Non-spherical polyvinyl alcohol particle or Tris-acryl gelatin microsphere
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Severance Hospital
Leiomyoma
Superior Hypogastric Nerve Block for Pain Control Post-uterine Fibroid Embolization
Uterine fibroid embolization (UFE) is now an accepted treatment of uterine fibroids. However the procedure is often very painful and, in many centres, patients are admitted overnight with patient controlled analgesic (PCA) pumps…
- Trial name
- NCT02270255
- Testing
- Superior hypogastric nerve block, 0.75% Ropivacaine, Subcutaneous injection
- Where
- Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Leiomyomas, Fertility
Fertility After Uterine Artery Embolisation for the Treatment of Leiomyomas
The main goal of this study is to evaluate spontaneous fertility after uterine leiomyomas embolization, in women between 18 and 40 years old.
- Trial name
- EFU (NCT00839722)
- Testing
- embolization
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris