Clinical trials: Uterine Disease
Cancer of the Cervix
Oral Ondansetron Versus Transdermal Granisetron (Sancuso) for Women With Cervical, Endometrial or Vaginal Cancer Receiving Pelvic Chemoradiation
The goal of this clinical research study is to compare granisetron (when given through a patch) to ondansetron (when taken by mouth) for reducing nausea and vomiting in women with cervical, endometrial, or vaginal cancer having…
- Trial name
- NCT01536392
- Testing
- Granisetron, Ondansetron, Questionnaires
- Where
- 2 sites in United States
- Volunteers
- 76 people
- Sponsor
- M.D. Anderson Cancer Center
Postpartum Hemorrhage
Ghana: The Barriers and Facilitators of Scaling up the Ellavi UBT for Postpartum Hemorrhage
The purpose of this implementation science study is to generate evidence that informs the successful uptake and adoption of the Ellavi UBT within Ghana's PPH management programs.
- Trial name
- NCT05340777
- Testing
- Training Obstetric staff on Ellavi UBT
- Where
- 3 sites in Ghana
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- PATH
Menorrhagia Due to Benign Causes
Reframing Endometrial Physiology by Advanced Integrated Research
Heavy menstrual bleeding (HMB) affects 1 in 3 women and can significantly impact quality of life. Despite its prevalence, there is no accessible and accurate diagnostic test.
- Trial name
- REPAIR (NCT07557992)
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Endometrial Hyperplasia
Levonorgestrel-Releasing Intrauterine System (LNG-IUS) in the Management of Atypical Endometrial Hyperplasia
The purpose of this research study is to compare the uterus tissue of women who receive an intrauterine system to treat their endometrial hyperplasia with the uterine tissue of women who receive megestrol acetate to treat their…
- Trial name
- NCT04897217
- Testing
- Megestrol Acetate, Levonorgestrel Drug Implant
- Sponsor
- Wake Forest University Health Sciences
Hodgkin's Disease, Cervical Cancer
Psychosocial Impact of Cancer-Related Female Infertility
The success of cancer treatment combined with the trend to delay childbearing is increasing the numbers of women survivors whose childbearing has been interrupted by cancer. For some, treatment has resulted in infertility.
- Conditions
- Hodgkin's Disease, Cervical Cancer, Breast Cancer, Lymphoma
- Trial name
- NCT00386217
- Testing
- Telephone Survey
- Where
- United States
- Volunteers
- 239 people
- Sponsor
- M.D. Anderson Cancer Center
Breast Cancer, Cervical Cancer
Breast and Cervical Cancer Educational Intervention for Latinas in Western New York
This pilot clinical trial studies a breast and cervical cancer educational intervention for Latinas in Western New York. An outreach program may help minority cancer patients overcome problems that keep them from receiving cancer…
- Trial name
- NCT01760850
- Testing
- educational intervention, questionnaire administration
- Where
- United States
- Volunteers
- 959 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Lymphocele, Endometrial Cancer
Application of Tachosil During Lymphadenectomy
The prevention of lymphoceles was assessed using collagen patch coated with the human coagulation factors (TachoSil, Nycomed International Management GmbH, Zurich, Switzerland; NCT Number ICMJE NCT01192022; Other Study ID Numbers…
- Conditions
- Lymphocele, Endometrial Cancer, Cervical Cancer
- Trial name
- NCT03752606
- Testing
- TACHOSIL GROUP
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Lublin
Cervical Cancer, Endometrial Cancer
Nutritional Supplements in Improving Quality of Life During First-Line Chemotherapy in Patients With Metastatic Gynecological Cancer
RATIONALE: Learning about the effect of nutritional supplements on quality of life in patients receiving chemotherapy for cancer may help doctors plan the best treatment.
- Conditions
- Cervical Cancer, Endometrial Cancer, Fallopian Tube Cancer, Ovarian Cancer
- Trial name
- NCT00905658
- Testing
- therapeutic nutritional supplementation, standard follow-up care
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Centre Oscar Lambret
Infertility
A Comparative Analysis of Arterial Blood Flow in Unexplained Infertility, Tubal Infertility and Fertile Groups
Factors affecting the success of the treatment of infertility can evaluate before and after embryo transfer in two stages. Most of the patients reach the embryo transfer stage.
- Trial name
- NCT02393235
- Testing
- doppler ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Suleymaniye Birth And Women's Health Education And Research Hospital
Infertility
Physiotherapy Treatment for Uterine Blood Flow Improved Dimensional Ultrasound Evaluated With Angiography
Ivanovski shows that by studying the vascular impedance can calculate the optimal uterine receptivity in IVF. A reduced vascular resistance and increased blood flow rate improves the chance of pregnancy. Dr. Luis T.
- Trial name
- NCT02437435
- Testing
- Reproductive Technique Gimilio
- Where
- Spain
- Volunteers
- 54 people
- Sponsor
- University of Valencia
Postpartum Hemorrhage, Twin
Oxytocin at Elective Cesarean Deliveries: A Dose-finding Study in Women With Twin Pregnancy
Postpartum hemorrhage (PPH) due to uterine atony is a major cause of maternal morbidity and mortality. Uterotonic drugs are used to improve the muscle tone of the uterus after birth and these are effective at reducing the…
- Trial name
- NCT04025658
- Testing
- Oxytocin
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Uterine Cervical Neoplasm
Online Adaptive Radiotherapy Cervical Cancer With Reduced Margin for Cervical Cancer
Online adaptive radiotherapy (oART) has demonstrated to be feasible to reduce planning target volume (PTV) margins for cervical cancer.
- Trial name
- NCT05880485
- Testing
- online adaptive radiotherapy
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking Union Medical College Hospital
Endometrial Cancer
RAD001 in Recurrent Endometrial Cancer Patients
The goal of this clinical research study is to learn if RAD001 can shrink or slow the growth of tumors in patients who have recurrent endometrial cancer. The safety of this drug will also be studied.
- Trial name
- NCT00087685
- Testing
- RAD001
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- M.D. Anderson Cancer Center
Postpartum Hemorrhage
Effects of Oxytocin and Carbetocin on Renal System in Cesarean Sections
The aim of this study is to evaluate the renal outcome of patients undergoing elective C/S where oxytocin or carbetocin is used for postpartum hemorrhage prophylaxis.
- Trial name
- NCT03939806
- Testing
- Oxytocin, Carbetocin
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ufuk University
Intrauterine Devices, Copper, Metrorrhagia
Tracking IUD Bleeding Experiences: An Evaluation of Bleeding Profiles in New Intrauterine Device Users
This study aims to use validated tools as well as new technology to examine changes in bleeding patterns among women who are initiating the copper T380A IUD.
- Conditions
- Intrauterine Devices, Copper, Metrorrhagia, Menstruation, Menstrual Cycle
- Trial name
- TRIBE (NCT02311478)
- Testing
- T380A Intrauterine Copper Contraceptive
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- University of Utah
Human Papilloma Virus, Uterine Cervical Neoplasms
HPV-test, Cervical Cancer and Follow-up
The investigators have planned this project to evaluate the follow-up program after surgery due to cervical cancer and to explore the possibilities for different tests of Human Papilloma Virus (HPV) in contributing to the…
- Conditions
- Human Papilloma Virus, Uterine Cervical Neoplasms, Recurrence
- Trial name
- NCT02096016
- Testing
- Human Papilloma Virus test from the vaginal vault
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Aarhus
Pregnancy, High Risk, Preterm Birth
Prevention of Preterm Birth by Screening of the Consistency Index and Length of the Uterine Cervix in Women With a Single Pregnancy
Preterm birth (PTB) is the major cause of perinatal morbidity and mortality. Worldwide, about 15 million babies are born too soon every year, causing 1.1 million deaths, as well as short- and long-term disability in countless…
- Conditions
- Pregnancy, High Risk, Preterm Birth, Cervix; Pregnancy, Obstetric Labor, Premature
- Trial name
- PreBirthCerv (NCT04444206)
- Testing
- Transvaginal ultrasound cervical length screening
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- University of Campania Luigi Vanvitelli
Preterm Birth, Cervical Incompetence
Preventing Preterm Birth With a Negative Pressure Cervical Cup: a Feasibility Study
The goal of this Phase I clinical trial is to generate proof-of-concept data to demonstrate that a cervical cup in combination with vacuum application will create negative pressure on uterine cervical tissue, thereby creating…
- Conditions
- Preterm Birth, Cervical Incompetence, Cervical Insufficiency, Short Cervix
- Trial name
- NCT05512052
- Testing
- Hannah Cervical Cup (2 mm Delta), Hannah Cervical Cup (4 mm Delta), Hannah Cervical Cup (6 mm Delta)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Galena Innovations, LLC
Postpartum Hemorrhage
Cervical Traction and Postpartum Hemorrhage
The purpose of the research conducted within the scope of the doctoral thesis study is to evaluate the effect of cervical traction applied at the end of the third stage of childbirth on the oxytocin level and postpartum bleeding…
- Trial name
- NCT06179147
- Testing
- cervical traction
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ege University
Endometrial Cancer, Abnormal Uterine Bleeding
ONSD as an ICP Marker in vNOTES and TLH
Patients undergoing conventional total laparoscopic hysterectomy (TLH) are typically placed in the Trendelenburg position with intraabdominal carbon dioxide (CO₂) insufflation.
- Conditions
- Endometrial Cancer, Abnormal Uterine Bleeding, Myoma;Uterus
- Trial name
- NCT07250178
- Testing
- vNOTES, TLH
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
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