Clinical trials: Uterine Diseases
Uterine Cervical Neoplasms
Urinary and Vaginal HPV Testing in Cervical Cancer Screening
Cervical cancer, caused by high-risk human papillomavirus (HPV) infection, poses a problem worldwide as it is the fourth most common female cancer.
- Trial name
- NCT05065853
- Testing
- urine self-sampling group, clinician-collected cervical sample group
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Dysmenorrhea, Heavy Menstrual Bleeding
Ultrasound Evaluation Versus Direct Measurement of Uterine Cavity Length
To determine if uterine cavity length on transabdominal pelvic ultrasound corresponds to uterine cavity length at time of IUD insertion.
- Conditions
- Dysmenorrhea, Heavy Menstrual Bleeding, Contraception
- Trial name
- NCT04425577
- Testing
- Transabdominal Ultrasound
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Children's Mercy Hospital Kansas City
Postpartum Bleeding
Postpartum Uterotonic Administration
The investigators are planning to determine the effect of the timing of oxytocin administration on the amount of blood loss, necessity for additional medical or surgical interventions.
- Trial name
- NCT02495272
- Testing
- Oxytocin
- Where
- Turkey (Türkiye)
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Bagcilar Training and Research Hospital
Adenomyosis, Assisted Reproductive Technology
Low Molecular Weight Heparin on the Adenomyosis Patients'IVF-ET Outcome
In assisted reproductive technology, adenomyosis patients are characterized by lower clinical pregnancy rate, lower implantation rate and higher abortion rate.
- Trial name
- NCT04741295
- Testing
- Low molecular weight heparin
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Nanjing University
Papillomavirus Infections
Phase I of Human Papillomavirus (HPV) DNA Plasmid (VGX-3100) + Electroporation for CIN 2 or 3
DNA vaccines, which are small pieces of DNA also known as plasmids, have several advantages over traditional vaccines such as live attenuated virus and recombinant protein-based vaccines.
- Trial name
- NCT00685412
- Testing
- VGX-3100
- Where
- 4 sites in United States, Puerto Rico
- Volunteers
- 18 people
- Sponsor
- Inovio Pharmaceuticals
Postpartum Hemorrhage
Study of Predictors of Failure of Sulprostone Treatment in Postpartum Hemorrhage
The investigators wish to identify potential factors predicting failure of second-line drug treatment (sulproston (Nalador®)): risk factors and factors linked to a failure to take initial care for PPH.
- Trial name
- NALAPOST (NCT06164236)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Strasbourg, France
Breast Cancer, Cervical Cancer
Cultivando la Salud: A Breast and Cervical Cancer Screening Promotion Program for Low-Income Puerto Rican Women
The overall goal of this education program is to increase breast and cervical cancer screening in low-income women in Puerto Rico through implementation of an evidence-based educational program that addresses both health…
- Trial name
- CLS (NCT04617236)
- Testing
- Cultivando La Salud
- Where
- Puerto Rico
- Volunteers
- 444 people, healthy volunteers welcome
- Sponsor
- University of Puerto Rico
Carcinoma of Unknown Primary, Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Blood Tests and Questionnaires in Studying Adherence to Preventative Swallowing Exercises in Participants With Metastatic Head and Neck Cancer
This trial uses blood tests and questionnaires to study how well participants with head and neck cancer that has spread to other places in the body adhere to swallowing exercises to prevent future disease.
- Conditions
- Carcinoma of Unknown Primary, Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
- Trial name
- NCT03010150
- Testing
- Biospecimen Collection, Questionnaire Administration
- Where
- United States
- Volunteers
- 471 people
- Sponsor
- M.D. Anderson Cancer Center
Uterine Myoma, Ovarian Cyst
The Effect of Different I:E Ratio on Gas Exchange of Patients Undergoing Gynecologic Laparoscopic Surgery With Trendelenburg Position
In patients undergoing gynecologic laparoscopic surgery with trendelenburg position, the disturbance of pulmonary gas exchange frequently occurs due to high intra-abdominal pressure.
- Conditions
- Uterine Myoma, Ovarian Cyst, Laparoscopic Gynecologic Surgery
- Trial name
- NCT01379313
- Testing
- conventional I:E ratio, 1:1 ratio, 2:1 group
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center
Human Papillomavirus Infection
A Study to Evaluate the Immunogenicity and Safety of HPV Vaccine in Healthy Female Participants Aged 9-26 Years in China
The study is to evaluate immune response induced by 9-valent HPV study vaccine is non-inferior to those induced by GARDASIL® 9 administrated with 3-dose schedule in female participants aged 20-26 years in China, if the immune…
- Trial name
- NCT05662020
- Testing
- Recombinant Nonavalent (types 6/11/16/18/31/33/45/52/58) Human Papillomavirus (HPV) Vaccine (Escherichia coli), GARDASIL® 9
- Where
- China
- Volunteers
- 2,750 people, healthy volunteers welcome
- Sponsor
- Beijing Health Guard Biotechnology, Inc
Uterine Cervical Incompetence
Dilapan-S Osmotic Dilator in Pre-induction of Labor
Non-interventional prospective data collection designed to evaluate clinical outcome on the efficacy of the use of Dilapan-S in the indication of labor pre-induction in women with/without a history of Caesarean section.
- Trial name
- NCT02098382
- Testing
- Dilapan-S
- Where
- Czechia
- Volunteers
- 125 people
- Sponsor
- Medicem International CR s.r.o.
Infertility of Uterine Origin, Implantation Failure
International Non-selection Study for ERA® Test in Patients With Previous Implantation Failures
Women´s period comprises different hormonal stages, being one of them the stage for maximum receptivity and proper embryo implantation.
- Trial name
- NCT06097559
- Testing
- Endometrial fluid and biopsy collection
- Where
- 8 sites in Argentina, Panama and 2 more
- Volunteers
- 738 people, healthy volunteers welcome
- Sponsor
- Igenomix
Malignant Female Reproductive System Neoplasm, Malignant Hepatobiliary Neoplasm
Acceptance and Commitment Therapy in Improving Well-Being in Patients With Stage III-IV Cancer and Their Partners
This pilot clinical trial studies how well acceptance and commitment therapy works in improving well-being in patients with stage III-IV cancer and their partners.
- Conditions
- Malignant Female Reproductive System Neoplasm, Malignant Hepatobiliary Neoplasm, Partner, Stage III Breast Cancer
- Trial name
- NCT03112668
- Testing
- Cognitive Behavior Therapy, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Myoma;Uterus, Polyp Endometrium
Remimazolam and Remifentanil Without Neuromuscular Blocking Agent
Remimazolam is a novel drug approved for induction and maintenance of general anesthesia. This study aims to check the appropriate dose and patient response by administering remimazolam and remifentanil in surgery that does not…
- Conditions
- Myoma;Uterus, Polyp Endometrium, Unspecified Condition Associated With Female Genital Organs and Menstrual Cycle
- Trial name
- NCT05025410
- Testing
- Remimazolam
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Seoul National University Bundang Hospital
Menorrhagia
Efficacy of Combined Contraceptive Vaginal Ring(NuvaRing)in Women With Idiopathic Menorrhagia
To compare the efficacy of a combined contraceptive vaginal ring (NuvaRing) and oral Norethisterone Acetate in treatment of Idiopathic heavy menstrual bleeding during fertile age
- Trial name
- NCT01266759
- Testing
- NuvaRing, Norethisterone Acetate tablets - 5mg
- Where
- Egypt
- Volunteers
- 95 people
- Sponsor
- Mansoura University
Cervical Cancer
Systemic Consolidation Therapy After Chemoradiation Therapy Following Operation for High Risk Early Stage Cervical Cancer
The purpose of this study is to determine the therapeutic efficacy and complications of systemic consolidation therapy with paclitaxel plus carboplatin following radical hysterectomy and adjuvant chemoradiation for high risk…
- Trial name
- NCT00592059
- Where
- South Korea
- Volunteers
- 77 people
- Sponsor
- Seoul National University Hospital
HPV Infections, Cervical Cancer Stage IIa
Immunogenicity and Safety of Quadrivalent HPV Vaccine in Healthy Chinese Female Subjects Aged 9 to 19 Years
This phase 3 study will evaluate the immunogenicity and safety of Quadrivalent HPV recombinant vaccine in Chinese females aged 9 to 26 years
- Conditions
- HPV Infections, Cervical Cancer Stage IIa, Vaginal Cancer, Genital Wart
- Trial name
- NCT05027776
- Testing
- 2-doses Group among 9-14 years, 3-doses Group among 9-19 years, 3-doses Group among 20-26 years
- Where
- China
- Volunteers
- 1,348 people, healthy volunteers welcome
- Sponsor
- Shanghai Bovax Biotechnology Co., Ltd.
Advanced Endometrial Carcinoma, Recurrent Endometrial Carcinoma
Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer
This phase III trial compares the effect of bevacizumab in combination with carboplatin, paclitaxel and pembrolizumab to the usual treatments of carboplatin and paclitaxel with or without pembrolizumab in treating patients with…
- Trial name
- NCT07198074
- Testing
- Bevacizumab, Biospecimen Collection, Carboplatin
- Where
- 304 sites in United States
- Volunteers
- 255 people
- Sponsor
- National Cancer Institute (NCI)
Menorrhagia, Pelvic Pain
Randomized Clinical Trial Comparing Conventional Laparoscopic and Robot-Assisted Laparoscopic Hysterectomy
Robotic-assisted surgery is becoming more prominent within the specialty of Gynecologic surgery with little direct evidence that it is if not better than traditional laparoscopic surgery, at least equivalent.
- Conditions
- Menorrhagia, Pelvic Pain, Hysterectomy
- Trial name
- NCT02118974
- Testing
- Hysterectomy
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Milton S. Hershey Medical Center
Infertility, Vaginal Blood Loss
A Virtual Reality System for Pain and Anxiety Management During Outpatient Hysteroscopy
To evaluate the effectiveness of VR as a distraction technique in the management of acute pain and anxiety during operative hysteroscopy in the outpatient setting.
- Trial name
- NCT04625920
- Testing
- SootheVR: AppliedVR, Los Angeles, California
- Where
- 2 sites in Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
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