Clinical trials: Uterine Fibroids
Endometriosis of the Cul-de-sac, Chocolate Cyst of Ovary
Peritoneal Cavity Conditioning Decreases Pain, Inflammation and Adhesions
Full conditioning of the peritoneal cavity during laparoscopic surgery will decrease post-operative pain, inflammation and adhesion formation.
- Conditions
- Endometriosis of the Cul-de-sac, Chocolate Cyst of Ovary, Fibroid/Myoma (Uterus/Cervix)
- Trial name
- NCT01344486
- Testing
- full conditioning, standard pneumoperitoneum
- Where
- Belgium
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Leiomyoma
A Long-Term Safety Study of Asoprisnil in the Treatment of Uterine Fibroids.
This study was designed to determine the long-term safety of asoprisnil 10 mg in women with one or more uterine fibroids after an initial 12 weeks in study M99-144.
- Trial name
- NCT00156182
- Testing
- Asoprisnil
- Volunteers
- 38 people
- Sponsor
- Abbott
Laser Hysteroscopic Ablation of Submucous Myoma
In-office Hysteroscopic Laser Ablation for Symptomatic Submucous Uterine Fibroids
To evaluate feasibility and efficacy of in-office hysteroscopic ablation of submucous uterine fibroid using diode laser
- Trial name
- NCT05604001
- Testing
- hysteroscopic ablation of submucous uterine fibroid using diode laser
- Where
- 4 sites in Israel, Italy and 1 more
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ariel University
Uterine Fibroids
Study of Volume Reduction of Uterine Fibroids After Embolization or Microwave Treatment
Uterine fibroids are benign tumors that occur most commonly in women of reproductive age. Symptoms of uterine fibroids may be heavy menstrual bleeding which may lead to anemia, pressure symptoms, bowel symptoms or urinary…
- Trial name
- MYOMIC1 (NCT02942537)
- Testing
- Microwave treatment, uterine artery embolization
- Where
- Sweden
- Volunteers
- 36 people
- Sponsor
- Karolinska Institutet
Fibroid Uterus
Temporary Artery Clipping for Robotically-assisted Myomectomy, a Multicentric Randomized Controlled Trial
This study aims to investigate the efficacy of temporary clipping of the uterine artery and utero-ovarian ligament during robotically assisted myomectomy (RAM) for uterine fibroids.
- Trial name
- TACROM (NCT06269809)
- Testing
- Temporary clipping of the uterine arteries and the utero-ovarian ligmants., No temporary clipping of the uterine arteries and the utero-ovarian ligmants.
- Where
- 4 sites in Belgium, France and 1 more
- Volunteers
- 82 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Uterine Myoma
Surgical Outcome of Two-port Laparoscopic Myomectomy
Study Objective: To evaluate the surgical outcome of laparoendoscopic two-sites myomectomy (LETS-M) and compare the difference between an experienced surgeon and three trainees. Design: A retrospective study.
- Trial name
- NCT04279626
- Testing
- LETS-M
- Where
- Taiwan
- Volunteers
- 204 people
- Sponsor
- National Taiwan University Hospital
Menorrhagia, Uterine Fibroids
Uterine Artery Occlusion for Fibroid Related Bleeding
The primary objective of this study is to evaluate the safety and effectiveness of Doppler guided Uterine Artery Occlusion (D-UAO) as treatment for the reduction of fibroid-associated symptoms.
- Trial name
- NCT00496067
- Testing
- Doppler-Guided Uterine Artery Occlusion Device
- Where
- 14 sites in Denmark, France and 5 more
- Volunteers
- 91 people
- Sponsor
- Ethicon, Inc.
Fibroid, Miscarriage in First Trimester
Fibroids and the Risk of Miscarriage: a Prospective Observational Study in an Early Pregnancy Population
The aim of this observational study is to whether fibroids increase the risk of miscarriage in women in our early pregnancy population.
- Conditions
- Fibroid, Miscarriage in First Trimester, Miscarriage in Second Trimester
- Trial name
- FiRM (NCT06986616)
- Where
- United Kingdom
- Volunteers
- 436 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Fibroids
Endometrial and Myometrial Changes, With and Without Fibroids
fibroids are common among women in fertile age. the relation between fibroids and infertility is controversial. our goal is to claculate a ratio between uterine cavity - endometrium \& myometrium in normal uterine s and study the…
- Trial name
- NCT01671215
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Meir Medical Center
Uterine Fibroids
Risk Factors for Uterine Fibroids: A Case Control Study
The proposed study is designed to estimate the proportion of 35-49 year-old women in a large urban health plan who have had fibroids.
- Trial name
- NCT00339547
- Where
- United States
- Volunteers
- 1,529 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Uterine Fibroids
Sonalleve Fibroid Ablation Pivotal Clinical Trial for MR-HIFU of Uterine Fibroids
The purpose of this clinical study is to determine whether treatment with the Philips Sonalleve Magnetic Resonance-guided High Intensity Focused Ultrasound (MR-HIFU) system is effective in the treatment symptomatic uterine…
- Trial name
- SOFIA (NCT01504308)
- Testing
- MR-HIFU treatment
- Where
- 9 sites in United States, Canada and 1 more
- Volunteers
- 49 people
- Sponsor
- Philips Healthcare
Myoma of Uterus
Clinical Trial to Evaluate the Efficacy and Safety of DW4902
A Multi-center, Randomized, Double-blind, Placebo-controlled, Therapeutic Exploratory, Phase II Clinical Trial for the Efficacy Investigation and Safety Evaluation of DW4902 in Patients with Uterine Fibroids.
- Trial name
- NCT07319520
- Testing
- DW4902 160mg, DW4902 240mg, DW4902 320mg
- Where
- South Korea
- Volunteers
- 71 people
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
Myoma;Uterus
Intraoperative Carbetocin to Decrease Blood Loss During Hysteroscopic Myomectomy
Submucous myomas represent one of the main indications of operative hysteroscopy. Since 1976 when Neuwirth and Amin reported the first five cases of excision of submucous myomas , several techniques have been developed in order…
- Trial name
- NCT04482959
- Testing
- Carbetocin, Sodium chloride 0.9%
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University Hospital
Endometriosis, Fibroids
Impact of Educational Videos on Pre-operative Anxiety
The goal of this clinical trial is to learn if educational videos can reduce pre-operative anxiety in patients undergoing minimally invasive gynecologic surgery.
- Conditions
- Endometriosis, Fibroids, Adenomyosis, Pelvic Pain
- Trial name
- NCT07740759
- Testing
- educational video
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- UConn Health
Heavy Menstrual Bleeding
Effectiveness of Truclear on Patient Quality of Life
This study aims to evaluate the quality of life in patients treated for submucosal leiomyomas using the Truclear hysteroscopic morcellator compared to women managed medically.
- Trial name
- HSCMyomecty (NCT02934789)
- Testing
- Hysteroscopic myomectomy with Truclear, Medical therapy
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- All For Women Healthcare, Illinois
Leiomyoma (Uterine Fibroids), Adenomyoma of Uterus
The Effect of Uterine Manipulator Use During Abdominal Hysterectomy on Postoperative Sexual Function
This prospective, single-center, randomized controlled trial aims to evaluate the effect of uterine manipulator use during total abdominal hysterectomy on postoperative female sexual function at 3 months, assessed by the Female…
- Conditions
- Leiomyoma (Uterine Fibroids), Adenomyoma of Uterus, Uterine Bleeding
- Trial name
- UMAH (NCT07431788)
- Testing
- Uterine Manipulator, Conventional Abdominal Hysterectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Erkan Gol
Fibroids
Tissue Removal During Hysterectomy: The Effect of Vaginal Versus Abdominal Morcellation on Surgical Outcomes
In this study the investigators will perform a randomized trial to compare the surgical outcomes of vaginal versus abdominal morcellation of the uterus during hysterectomy.
- Trial name
- NCT02703246
- Testing
- abdominal morcellation, vaginal morcellation
- Where
- United States
- Sponsor
- George Washington University
Myomectomy, Uterine Leiomyoma
Uterine Tourniquet at Open Myomectomy
The aim of study is to compare triple tourniquet vs. single tourniquet to reduce blood loss at open myomectomy.
- Trial name
- NCT02049242
- Testing
- triple tourniquet, Single tourniquet
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Uterine Fibroids (UF)
Ultrasound-Guided Stellate Ganglion Block Plus Propofol for Perimenopausal Insomnia With Anxiety
Laparoscopic myomectomy is a commonly performed minimally invasive gynecologic procedure. However, surgical trauma, tracheal intubation, and pneumoperitoneum may induce pronounced perioperative stress responses, resulting in…
- Trial name
- SGB-PROP-PIA (NCT07384468)
- Testing
- Ultrasound-Guided Stellate Ganglion Block
- Where
- China
- Volunteers
- 233 people
- Sponsor
- Xiaochen Ji
Heavy Uterine Bleeding, Uterine Fibroids
Safety and Efficacy of Elagolix in Pre-Menopausal Women With Heavy Uterine Bleeding and Uterine Fibroids
The purpose of this proof-of-concept study is to assess the safety and effectiveness of elagolix versus placebo to reduce uterine bleeding associated with uterine fibroids, and to reduce fibroid volume and uterine volume in…
- Trial name
- NCT01441635
- Testing
- Elagolix, Estradiol/Norethindrone acetate (E2/NETA), Estradiol
- Volunteers
- 271 people
- Sponsor
- AbbVie (prior sponsor, Abbott)