Clinical trials: Uterine Neoplasm
CIN2, Therapy
Expectancy as Alternative to Treatment for Cervical Intraepithelial Neoplasia Grade 2 Among Women 25 - 30 Years of Age
In the Swedish organised cervical screening program precursors of cervical cancer are detected and treated. Most precursor lesions detected by screening heal spontaneously. Those who progress do it slowly.
- Trial name
- EXCIN2 (NCT03177863)
- Testing
- Expectancy
- Where
- 5 sites in Sweden
- Volunteers
- 125 people
- Sponsor
- Sahlgrenska University Hospital
Hodgkin's Disease, Cervical Cancer
Psychosocial Impact of Cancer-Related Female Infertility
The success of cancer treatment combined with the trend to delay childbearing is increasing the numbers of women survivors whose childbearing has been interrupted by cancer. For some, treatment has resulted in infertility.
- Conditions
- Hodgkin's Disease, Cervical Cancer, Breast Cancer, Lymphoma
- Trial name
- NCT00386217
- Testing
- Telephone Survey
- Where
- United States
- Volunteers
- 239 people
- Sponsor
- M.D. Anderson Cancer Center
Breast Cancer, Cervical Cancer
Breast and Cervical Cancer Educational Intervention for Latinas in Western New York
This pilot clinical trial studies a breast and cervical cancer educational intervention for Latinas in Western New York. An outreach program may help minority cancer patients overcome problems that keep them from receiving cancer…
- Trial name
- NCT01760850
- Testing
- educational intervention, questionnaire administration
- Where
- United States
- Volunteers
- 959 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Lymphocele, Endometrial Cancer
Application of Tachosil During Lymphadenectomy
The prevention of lymphoceles was assessed using collagen patch coated with the human coagulation factors (TachoSil, Nycomed International Management GmbH, Zurich, Switzerland; NCT Number ICMJE NCT01192022; Other Study ID Numbers…
- Conditions
- Lymphocele, Endometrial Cancer, Cervical Cancer
- Trial name
- NCT03752606
- Testing
- TACHOSIL GROUP
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Lublin
Recurrent Uterine Corpus Carcinoma, Stage III Uterine Corpus Cancer
Biomarkers in Tumor Tissue Samples From Patients With Stage III, Stage IV, or Recurrent Endometrial Cancer
This research study is studying biomarkers in tissue samples from patients with stage III, stage IV, or recurrent endometrial cancer.
- Conditions
- Recurrent Uterine Corpus Carcinoma, Stage III Uterine Corpus Cancer, Stage IV Uterine Corpus Cancer
- Trial name
- NCT01164735
- Testing
- Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 169 people
- Sponsor
- Gynecologic Oncology Group
Cervical Cancer, Endometrial Cancer
Nutritional Supplements in Improving Quality of Life During First-Line Chemotherapy in Patients With Metastatic Gynecological Cancer
RATIONALE: Learning about the effect of nutritional supplements on quality of life in patients receiving chemotherapy for cancer may help doctors plan the best treatment.
- Conditions
- Cervical Cancer, Endometrial Cancer, Fallopian Tube Cancer, Ovarian Cancer
- Trial name
- NCT00905658
- Testing
- therapeutic nutritional supplementation, standard follow-up care
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Centre Oscar Lambret
Uterine Cervical Neoplasm
Online Adaptive Radiotherapy Cervical Cancer With Reduced Margin for Cervical Cancer
Online adaptive radiotherapy (oART) has demonstrated to be feasible to reduce planning target volume (PTV) margins for cervical cancer.
- Trial name
- NCT05880485
- Testing
- online adaptive radiotherapy
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking Union Medical College Hospital
Endometrial Cancer
RAD001 in Recurrent Endometrial Cancer Patients
The goal of this clinical research study is to learn if RAD001 can shrink or slow the growth of tumors in patients who have recurrent endometrial cancer. The safety of this drug will also be studied.
- Trial name
- NCT00087685
- Testing
- RAD001
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- M.D. Anderson Cancer Center
Surgery
LapBox® Manual Containment System
This study to evaluate the leak integrity of the LapBox Manual Containment System for laparoscopic hysterectomy and myomectomy. The goal is to determine the integrity of this containment system in order to increase surgical…
- Trial name
- NCT07767968
- Testing
- LapBox Manual Containment System, Standard of Care Specimen Bag
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Wisconsin, Madison
Human Papilloma Virus, Uterine Cervical Neoplasms
HPV-test, Cervical Cancer and Follow-up
The investigators have planned this project to evaluate the follow-up program after surgery due to cervical cancer and to explore the possibilities for different tests of Human Papilloma Virus (HPV) in contributing to the…
- Conditions
- Human Papilloma Virus, Uterine Cervical Neoplasms, Recurrence
- Trial name
- NCT02096016
- Testing
- Human Papilloma Virus test from the vaginal vault
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Aarhus
Uterine Polyps, Uterine Fibroids
Office Hysteroscopy Versus Operating-room Hysteroscopy for Uterine Lesions
HYPHOP is a multicenter, randomized clinical trial comparing two care pathways for women who need operative hysteroscopy to treat intrauterine lesions, such as uterine polyps, small submucosal fibroids, or retained pregnancy…
- Conditions
- Uterine Polyps, Uterine Fibroids, Retained Products of Conception
- Trial name
- HYPHOP (NCT07908615)
- Testing
- Operating-room hysteroscopy with resectoscope, Outpatient hysteroscopic morcellation/aspiration
- Where
- 9 sites in France
- Volunteers
- 474 people
- Sponsor
- Nantes University Hospital
Endometrial Cancer, Abnormal Uterine Bleeding
ONSD as an ICP Marker in vNOTES and TLH
Patients undergoing conventional total laparoscopic hysterectomy (TLH) are typically placed in the Trendelenburg position with intraabdominal carbon dioxide (CO₂) insufflation.
- Conditions
- Endometrial Cancer, Abnormal Uterine Bleeding, Myoma;Uterus
- Trial name
- NCT07250178
- Testing
- vNOTES, TLH
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Ovarian Cancer, Sarcoma
Dolastatin 10 in Treating Patients With Recurrent or Metastatic Soft Tissue Sarcoma
Phase II trial to study the effectiveness of dolastatin 10 in treating patients who have recurrent or metastatic soft tissue sarcoma.
- Trial name
- NCT00003778
- Testing
- dolastatin 10
- Where
- 4 sites in United States
- Volunteers
- 37 people
- Sponsor
- National Cancer Institute (NCI)
Cervical Cancer, HPV Infection
Human Papilloma Virus (HPV) Self-collection and Women Adherence
Despite declining mortality in high-income countries, cervical cancer continues to be a public health problem in low and middle -income countries.
- Trial name
- NCT05059015
- Testing
- CERVICAL HPV, SELF SAMPLING HPV
- Where
- Colombia
- Volunteers
- 80 people
- Sponsor
- Instituto Nacional de Cancerologia, Columbia
Solid Tumor
Dose-Esc/Exp RMC4630 & Cobi in Relapsed/Refractory Solid Tumors & RMC4630& Osi in EGFR+ Locally Adv/Meta NSCLC
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetic (PK), and pharmacodynamic (PD) profiles of RMC-4630 and cobimetinib in adult participants with relapsed/refractory solid tumors with specific…
- Trial name
- NCT03989115
- Testing
- RMC-4630, Cobimetinib, Drug: Osimertinib
- Where
- 24 sites in United States, South Korea
- Volunteers
- 113 people
- Sponsor
- Revolution Medicines, Inc.
Endometrial Cancer
Revealing Engagement Patterns Among Endometrial Cancer Patients
The study intends to investigate the personal experiences of endometrial cancer patients who take part in a separate clinical study including a specific medication intervention.
- Trial name
- NCT05998798
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.
Cervical Cancer, Endometrial Cancer
Evaluation of Fluciclovine Uptake in Patients With Cervical, Ovarian Epithelial or Endometrial Cancers.
An important part of staging and deciding the method of treatment is knowing areas of how cancer is involved. Diagnostic imaging is often used to determine the location of the cancer using techniques like nuclear medicine, MRI…
- Conditions
- Cervical Cancer, Endometrial Cancer, Ovarian Epithelial Cancer
- Trial name
- NCT03349463
- Testing
- Fluciclovine F18
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Bital Savir-Baruch
Cervical Cancer, Locally Advanced Cervical Cancer
Nivolumab in Association With Radiotherapy and Cisplatin in Locally Advanced Cervical Cancers Followed by Adjuvant Nivolumab for up to 6 Months (NiCOL)
To date, the majority of clinical trials on checkpoint inhibitors have tested these agents as monotherapy, and the next logical step is to evaluate rational therapeutic associations.
- Trial name
- NiCOL (NCT03298893)
- Testing
- Nivolumab Injection, Cisplatin, radiotherapy
- Where
- 3 sites in France
- Volunteers
- 21 people
- Sponsor
- Institut Curie
Endometrial Carcinoma, P53 Mutation
A Study of Various Treatments in Serous or p53 Abnormal Endometrial Cancer
This is an umbrella, two-arm, multi-stage, phase II trial. The purpose of the trial in the early stage cohort is to determine if EBRT improves disease free survival (defined as the time from random assignment to disease…
- Conditions
- Endometrial Carcinoma, P53 Mutation, Serous Carcinoma
- Trial name
- CAN-STAMP (NCT04159155)
- Testing
- External Beam Radiation, Niraparib, Vaginal high-dose rate brachytherapy
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- University Health Network, Toronto
Cervical Cancer
Radiation Therapy or Chemoradiation, Interstitial Brachytherapy in Combination With Hyperthermia in Advanced Cervical Cancer
The combination of radiation therapy or chemoradiation with Interstitial brachytherapy for advanced cervical cancer (pN+, FIGO-Stage II B - IV A is standard of therapy.
- Trial name
- NCT03249519
- Testing
- Radiation, brachytherapy, Cisplatin
- Where
- Germany
- Volunteers
- 999 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
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