Clinical trials: Uterine Prolapse
Prolapse Genital, Anatomical Pathological Condition
The Change in Vaginal Axis on MRI After Uterus Preserving Laparoscopic Lateral Mesh Suspension
Laparoscopic lateral mesh suspension is emerged as a practical, safe and feasible alternative to sacropexy to treat female genital apical prolapse.
- Trial name
- NCT03772015
- Testing
- Magnetic resonance imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Sexual Function
Evaluating Sexual Function After Vaginal Repair With Perineorrhaphy
This is a single center, double-blind, randomized controlled trial evaluating the change in sexual function in women undergoing vaginal repair for pelvic organ prolapse.
- Trial name
- FaVR (NCT01779739)
- Testing
- Perineorrhaphy
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- Wake Forest University Health Sciences
Degree of Uterine Prolapse and Its Effect on Quality of Life
Quality of Life Assessment in Patients With Different Degrees of Pelvic Organ Prolapse
Study design: The study building by two design a descriptive exploratory research design and quasi experimental research design were utilized in the present study Setting of the study: This study was conducted at the Outpatient…
- Trial name
- NCT07080203
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Sohag University
Prolapse, Vaginal, Stress Urinary Incontinence
Perineal Massage for Pessary Examinations
Pessaries are effective non-surgical devices for reduction of prolapse. However, use of pessaries are limited in some women due to patient discomfort.
- Conditions
- Prolapse, Vaginal, Stress Urinary Incontinence, Pessaries, Pain
- Trial name
- NCT06416982
- Testing
- Perineal massage
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of North Carolina, Chapel Hill
Vaginal Prolapse
Comparison of Two Vaginal Mesh Kits in the Management of Vaginal Prolapse
Our study is a non-randomized prospective study compared two groups matched for anterior/apical POP-Q grade: 84 received Elevate Ant™ single-incision mesh (group A) and 42 Perigee™ transvaginal mesh (group B).
- Trial name
- ELEPE (NCT03187574)
- Testing
- Elevate Ant™, Perigee™
- Volunteers
- 126 people
- Sponsor
- Hospices Civils de Lyon
Uterine Prolapse, Urine Incontinence
The Assessment of Fibrin Clot Phenotype and Thrombin Generation in Women After Urogynecological Surgeries.
Determination of fibrin clot properties along with thrombin generation in women after urigynecological surgery.
- Trial name
- NCT07295782
- Testing
- determination of fibrin clot properties
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Vaginal Prolapse
Comparison Between Transvaginal Mesh and Traditional Surgery for Pelvic Organ Prolapse
Pelvic organ prolapse is characterized by a lack of pelvic floor support causing the pelvic organs and vaginal walls to protrude.
- Trial name
- NCT00566917
- Testing
- Anterior colporrhaphy, Anterior PROLIFT
- Where
- 53 sites in Denmark, Finland and 2 more
- Volunteers
- 400 people
- Sponsor
- Karolinska Institutet
Pelvic Organ Prolapse, Pelvic Floor Prolapse
Laparoscopic Lateral Suspension With Mesh & Sacrocervicopexy for the Treatment of Uterine Prolapse
This study is aimed to compare the efficiency of two uterus-preserving laparoscopic methods to treat uterine prolapse in a randomized controlled trial.
- Trial name
- NCT03421457
- Testing
- Uterus-preserving laparoscopic lateral suspension with mesh, Uterus-preserving laparoscopic sacrocervicopexy with mesh
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Pelvic Organ Prolapse (POP)
Restorelle Direct Fix Anterior and Posterior (A&P) for Female Pelvic Organ Prolapse: A Prospective Post Market Study
This is a prospective, multi-center study designed to assess the palpability of the Restorelle Direct Fix A\&P mesh after vaginal reconstruction surgery.
- Trial name
- (A&P) (NCT01378065)
- Testing
- Restorelle Direct Fix A&P
- Where
- 6 sites in United States
- Volunteers
- 31 people
- Sponsor
- Coloplast A/S
Uterine Fibroid, Uterine Bleeding
4K Versus 3D Laparoscopic Colporraphy by Surgeons in Training: a Prospective Randomized Trial
This prospective randomized trial aims to assess if the operative time of vaginal cuff suture performed by trainees could be reduced using 3D laparoscopy instead of 4K laparoscopy.
- Conditions
- Uterine Fibroid, Uterine Bleeding, Uterine Prolapse
- Trial name
- NCT04637022
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Catholic University of the Sacred Heart
Vaginal Prolapse
Sacrocolpopexy With Posterior Repair Obstructed Defecation Symptoms
Participants who undergo laparoscopic sacrocolpopexy (LSCP) plus posterior repair (PR) will demonstrate greater improvement bowel symptom scores compared to participants who undergo LSCP alone at 3 months postoperatively.
- Trial name
- NCT03658395
- Testing
- Laparoscopic Sacrocolopopexy, Posterior repair
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Oklahoma
Prolapse, Vaginal, Prolapse, Uterine
Impact of Preop Video on Patient Anxiety
To determine whether a pre-operative educational video has an impact on the anxiety of patients undergoing vaginal prolapse surgery
- Conditions
- Prolapse, Vaginal, Prolapse, Uterine, Prolapse; Female
- Trial name
- NCT05633901
- Testing
- Educational Video, Standard Counseling
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- TriHealth Inc.
Urethra Issue, Pelvic Organ Prolapse
Lessons on Urethral Lidocaine in Urodynamics
This trial will assess whether use of intraurethral 2% lidocaine jelly meaningfully impacts sensation during filling (i.e., a change of more than 25% of first sensation, first desire to void, strong desire to void, or maximum…
- Conditions
- Urethra Issue, Pelvic Organ Prolapse, Urinary Incontinence, Vaginal Vault Prolapse
- Trial name
- LULU (NCT04038099)
- Testing
- Water-Based Vaginal Lubricant, lidocaine topical
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Texas Southwestern Medical Center
Urinary Retention, Uterine Prolapse
Does Spinal Anesthesia for Prolapse Surgery With Lead to Urinary Retention?
The purpose of the study is to compare the risk of being unable to urinate shortly after surgery, also called acute post-operative urinary retention (POUR) between spinal and general anesthesia in women who undergo outpatient…
- Trial name
- NCT02547155
- Testing
- Spinal anesthesia, General anesthesia
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Vaginal Prolapse
Physiologic Elasticity Changes During Pregnancy and After Labor.
Female pregnant patients in their 2nd trimester will be evaluated for vaginal elasticity using vaginal tactile imaging in addition to elasticity evaluation during the 3rd trimester and 6 weeks postpartum.
- Trial name
- NCT03930290
- Testing
- Vaginal tactile imager
- Where
- Israel
- Volunteers
- 12 people
- Sponsor
- Rambam Health Care Campus
Pelvic Organ Prolapse
The ELEGANT Trial: Elevate Transvaginal Mesh vs. Anterior Colporrhaphy
This study is designed to compare the safety and efficacy of a commercially available mesh kit used for surgical repair of anterior vaginal wall prolapse with traditional suture repair surgery.
- Trial name
- NCT01497171
- Testing
- Elevate Mesh, Anterior Colporrhaphy
- Where
- 6 sites in United States, Germany
- Volunteers
- 5 people
- Sponsor
- Emanuel Trabuco
Uterine Prolapse
Prospective Analysis of Restorelle in the Treatment of Uterine Prolapse
The purpose of this study is to determine the long term performance of Restorelle system for the treatment of uterine prolapse.
- Trial name
- NCT02921451
- Testing
- Restorelle Smartmesh
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Michigan Institution of Women's Health PC
Pelvic Organ Prolapse, Urinary Incontinence
One Year Outcome After Robotic Assisted Laparoscopic Sacral Colpopexy, a Case Series Review
Robotic approach to sacral colpopexy is a relatively new procedure. The literature is scarce in regard to its long-term outcomes. This advanced procedure is offered at MMH through the Urogynecology division.
- Trial name
- NCT01055860
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Atlantic Health System
Uterine Prolapse
Does Doing Pelvic Floor Exercise Ease Symptoms for Women Living With Prolapse?
The purpose of this study is to investigate the feasibility of undertaking a multi-centre randomised controlled trial of the effectiveness of a pelvic floor muscle training (PFMT) intervention for women with pelvic organ prolapse.
- Trial name
- NCT00158626
- Testing
- pelvic floor muscle training
- Where
- 2 sites in United Kingdom
- Volunteers
- 50 people
- Sponsor
- Glasgow Caledonian University
Uterine Prolapse, Stage III
GYNECARE PROSIMA* Procedure Versus Modified Total Pelvic Floor Reconstructive Surgery for Uterine Prolapse Stage III
Pelvic Organ prolapse (a feeling of bulge in the vagina) may cause some distressing symptoms such as loss of control of the bowel or bladder, and may also cause problems with patient's sex life.
- Trial name
- NCT01396109
- Testing
- Procedure: TVH and GYNECARE PROSIMA* Pelvic Floor Repair System, Procedure: TVH and Modified Pelvic Floor Reconstruction Surgery with mesh
- Where
- 10 sites in China
- Volunteers
- 200 people
- Sponsor
- Peking Union Medical College Hospital