Clinical trials: Uterus Prolapse
Uterine Prolapse, Urinary Incontinence
The Immune Reactivity of Biofilms in Vaginal Mesh Erosion.
Aging, birth trauma and extensive pelvic surgery are the causes known to cause advanced pelvic organ prolaspe, fecal as well as urinary incontinence.
- Conditions
- Uterine Prolapse, Urinary Incontinence, Fecal Incontinence
- Trial name
- NCT00564044
- Testing
- excision of the protruding mesh and its surrounding vaginal tissue
- Where
- Taiwan
- Volunteers
- 82 people
- Sponsor
- Chang Gung Memorial Hospital
Prolapse, Vaginal
Vaginal Native Tissues Repair for Pelvic Organ Prolapse
The aim of the study is to assess at one year the effectiveness of the vaginal patch plastron in comparison of the anterior colporraphy through a combined definition of success: anatomic and functional.
- Trial name
- TAPP (NCT03875989)
- Testing
- Anterior colporraphy, vaginal patch plastron
- Where
- 9 sites in France
- Volunteers
- 214 people
- Sponsor
- University Hospital, Limoges
Anterior Vaginal Wall Prolapse With/Without Apical/Uterine Descent
Multicenter, Prospective, Non-randomized, Single-arm, Interventional Study for the Evaluation of the Safety and Preformance of the SRS Device for the Treatment of Pelvic Organ Prolapse
A prospective, single arm, multi-center clinical study to evaluate the safety and performance of the SRS (Lyra Medical) vaginal mesh in POP patients
- Trial name
- NCT03195361
- Testing
- SRS - Self Retaining Support system
- Where
- 3 sites in Israel
- Volunteers
- 50 people
- Sponsor
- Lyra Medical Ltd.
Vaginal Prolapse
Comparison Between Transvaginal Mesh and Traditional Surgery for Pelvic Organ Prolapse
Pelvic organ prolapse is characterized by a lack of pelvic floor support causing the pelvic organs and vaginal walls to protrude.
- Trial name
- NCT00566917
- Testing
- Anterior colporrhaphy, Anterior PROLIFT
- Where
- 53 sites in Denmark, Finland and 2 more
- Volunteers
- 400 people
- Sponsor
- Karolinska Institutet
Pelvic Organ Prolapse
Uphold Mesh for the Surgical Treatment of Uterine-predominant Prolapse
The primary objective of this study is to evaluate the efficacy of the UpholdTM LITE mesh over a 12 month follow up period, using a composite outcome including a good anatomical correction for both anterior and apical…
- Trial name
- NCT01559168
- Testing
- UpholdTM LITE placement
- Where
- 13 sites in France
- Volunteers
- 121 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Genital Diseases, Female, Hysterotomy; Affecting Fetus
Effect of Salpingectomy During Conservative Hysterectomy
The study compares the effect of bilateral salpingectomy associated with conservative hysterectomy on ovarian function to the standard hysterectomy with conservation of both ovaries and tubes in terms of hormone assays, ovarian…
- Conditions
- Genital Diseases, Female, Hysterotomy; Affecting Fetus, Leiomyomata Uteri, Adenomyosis, Endometriosis
- Trial name
- SALPINGOVA (NCT01628432)
- Testing
- conservative hysterectomy I, Conservative hysterectomy II
- Where
- 7 sites in France
- Volunteers
- 350 people
- Sponsor
- University Hospital, Tours
Vaginal Vault Prolapse, Enterocele
Sacrocolpopexy Versus Vaginal Mesh Procedure for Pelvic Prolapse
Pelvic prolapse is one of the most frequent pathology in Gynecology. Recurrency of the prolapse after primary surgery is relatively high, 15-30%.
- Conditions
- Vaginal Vault Prolapse, Enterocele, Uterine Prolapse, Cystocele
- Trial name
- NCT01097200
- Testing
- Elevate mesh, Sacrocolpopexy
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Francisco Carmona
Prolapse of the Uterus
Evaluation of the Position of Promontofixation Prostheses in Perineal Ultrasound
Indirect promontofixation with prostheses is the standard surgical technique for the reference of uterine prolapse. There is no validated examination to control the position of the prostheses postoperatively.
- Trial name
- PROMONOTECHO (NCT03634878)
- Testing
- perineal ultrasound
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Poitiers University Hospital
Uterine Prolapse, Vault Prolapse, Vaginal
Pectopexy Autologous Vs Mesh
prospective comparative study describing using autologous graft for uterine- vault - cervical suspension vs mesh in treatment of apical prolapse
- Trial name
- NCT06524700
- Testing
- pectopexy mesh, pectopexy autologous
- Where
- 2 sites in Egypt, Saudi Arabia
- Volunteers
- 20 people
- Sponsor
- Ain Shams Maternity Hospital
Uterovaginal Prolapse
Study of Uterine Prolapse Procedures - Randomized Trial
The primary purpose of this randomized clinical trial is to compare the effectiveness and safety of two transvaginal apical suspension strategies for uterovaginal prolapse: a mesh augmented hysteropexy versus vaginal hysterectomy…
- Trial name
- SUPeR (NCT01802281)
- Testing
- Uterosacral ligament suspension, Uphold® LITE
- Where
- 8 sites in United States
- Volunteers
- 183 people
- Sponsor
- NICHD Pelvic Floor Disorders Network
Uterine Prolapse, Urine Incontinence
The Assessment of Fibrin Clot Phenotype and Thrombin Generation in Women After Urogynecological Surgeries.
Determination of fibrin clot properties along with thrombin generation in women after urigynecological surgery.
- Trial name
- NCT07295782
- Testing
- determination of fibrin clot properties
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Urinary Retention, Uterine Prolapse
Does Spinal Anesthesia for Prolapse Surgery With Lead to Urinary Retention?
The purpose of the study is to compare the risk of being unable to urinate shortly after surgery, also called acute post-operative urinary retention (POUR) between spinal and general anesthesia in women who undergo outpatient…
- Trial name
- NCT02547155
- Testing
- Spinal anesthesia, General anesthesia
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Pelvic Organ Prolapse
Abdominal Sacral Hysteropexy Versus Vaginal Sacrospinous Hysteropexy
The aim of the current study is to compare abdominal sacral cervicopexy with vaginal sacrospinous cervicopexy in women with apical prolapse in terms of operative time, procedures safety and efficacy.
- Trial name
- NCT04850365
- Testing
- Hysteropexy
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Pelvic Organ Prolapse, Abnormal Uterine Bleeding
Evaluating Artisential Laparoscopic Instruments in Gynecologic Surgery
This study evaluates the efficacy and safety of Artisential laparoscopic instruments in minimally invasive gynecologic surgery.
- Conditions
- Pelvic Organ Prolapse, Abnormal Uterine Bleeding, Mesh Augmentation, Laparoscopic Surgery
- Trial name
- MIGS-ART (NCT06050161)
- Testing
- Articulating laparoscopic instrument, Conventional laparoscopic instrument, Robotic surgical instrument
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kern Medical Center
Uterine Prolapse
Comparison of Laparoscopic to Vaginal Surgical Repair for Uterine Prolapse
Investigators intend to conduct a prospective randomized trial to compare vaginal hysterectomy with uterosacral colposuspension to laparoscopic supracervical hysterectomy with sacrocervicopexy.
- Trial name
- NCT01594372
- Testing
- Laparoscopic supracervical hysterectomy with sacropexy, Vaginal hysterectomy with uterosacral colposuspension
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Brigham and Women's Hospital
Cholecystitis, Endometriosis
Deep Versus Moderate Neuromuscular Blockade During Laparoscopic Surgery
This is a two period cross-over study randomizing patients undergoing laparoscopic surgery into 2 different groups: group 1 in which patients receive "deep neuromuscular blockade" in the beginning portion of their laparoscopic…
- Conditions
- Cholecystitis, Endometriosis, Bowel Obstruction, Fibroids
- Trial name
- NCT02812186
- Testing
- Deep to Moderate NMB, Moderate to Deep NMB, Rocuronium
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Stony Brook University
Cystocele, Uterine Prolapse
Outcomes of Anterior Colporrhaphy Versus Graft Reinforced Anterior Prolapse Repair
The purpose of this study is determine whether grafted anterior vaginal prolapse repair is more effective and associated with less complications than prolapse repair with suture.
- Conditions
- Cystocele, Uterine Prolapse, Urinary Incontinence
- Trial name
- NCT00535301
- Testing
- grafted anterior prolapse repair, sutured anterior vaginal prolapse repair
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Pelvic Organ Prolapse (POP), Genital Prolapse
Safety and Performance of a Pelvic Floor Mesh Implant (LatGYNious)
The purpose of the clinical investigation is to verify that the investigational device (LatGYNious) is appropriate to significantly improve the pelvic organ prolapse in patients.
- Conditions
- Pelvic Organ Prolapse (POP), Genital Prolapse, Uterus Prolapse, Laparoscopic Surgery
- Trial name
- NCT07066761
- Testing
- Laparoscopic lateral suspension with surgical mesh (LatGYNious)
- Where
- 5 sites in Austria, Germany
- Volunteers
- 85 people
- Sponsor
- A.M.I. Agency for Medical Innovations GmbH
Overactive Bladder
Assessment of Potential Biomarkers in Women With Symptoms of Overactive Bladder and Pelvic Organ Prolapse
The objective of this study is to investigate the role of certain biomarkers in the initial assessment of women with overactive bladder (OAB).
- Trial name
- NCT03516292
- Testing
- Urinary Nerve Growth Factor
- Where
- Greece
- Volunteers
- 108 people
- Sponsor
- Aristotle University Of Thessaloniki
Vaginal Prolapse
Surgical Outcomes of Vaginal Prolapse Repair With Elevate
The purpose of this study is to evaluate outcomes in patients having vaginal prolapse repair with the Elevate prolapse repair kit and compare these outcomes to patients who had a repair with Prolift. .
- Trial name
- NCT01190618
- Where
- United States
- Volunteers
- 417 people
- Sponsor
- Larry Sirls