Clinical trials: Uterus Prolapse
Vaginal Prolapse
The Use of Avaulta for Anterior Repair
Summary: Vaginal prolapse is a well-known disease and is observed in approximately 11% of all postmenopausal women and tending to increase with age.
- Trial name
- NCT00918099
- Testing
- Avaulta mesh, Anterior repair
- Where
- Denmark
- Volunteers
- 130 people
- Sponsor
- Zealand University Hospital
Sexual Function
Evaluating Sexual Function After Vaginal Repair With Perineorrhaphy
This is a single center, double-blind, randomized controlled trial evaluating the change in sexual function in women undergoing vaginal repair for pelvic organ prolapse.
- Trial name
- FaVR (NCT01779739)
- Testing
- Perineorrhaphy
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- Wake Forest University Health Sciences
Female Urogenital Diseases, Urinary Incontinence
Clinical Trial of "Magic Gyno" Laser Device
The aim of this prospective study is investigation of efficiency and safety of medical device "Magic Gyno" in accordance with the stated purpose.
- Conditions
- Female Urogenital Diseases, Urinary Incontinence, Prolapse Genital, Menopausal Syndrome
- Trial name
- NCT05463081
- Testing
- Laser treatment, Blood test, Clinical urine test
- Where
- Russia
- Volunteers
- 70 people
- Sponsor
- MeLSyTech, Ltd
Pelvic Organ Prolapse
Randomized,Multicentric Study to Treat Prolapse After Hysterectomy With Amreich Procedure or Total Prolift Procedure
Head to Head comparison of perioperative complications and secondary the impact of operation techniques with or without mesh on patients suffering from pelvic organ prolapse on quality of life.
- Trial name
- NCT00572702
- Testing
- Vaginal fixation Amreich-Richter, Prolift total
- Where
- 5 sites in Czechia
- Volunteers
- 200 people
- Sponsor
- Charles University, Czech Republic
Uterine Prolapse
Prospective Analysis of Restorelle in the Treatment of Uterine Prolapse
The purpose of this study is to determine the long term performance of Restorelle system for the treatment of uterine prolapse.
- Trial name
- NCT02921451
- Testing
- Restorelle Smartmesh
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Michigan Institution of Women's Health PC
Vaginal Prolapse
Sacrocolpopexy With Posterior Repair Obstructed Defecation Symptoms
Participants who undergo laparoscopic sacrocolpopexy (LSCP) plus posterior repair (PR) will demonstrate greater improvement bowel symptom scores compared to participants who undergo LSCP alone at 3 months postoperatively.
- Trial name
- NCT03658395
- Testing
- Laparoscopic Sacrocolopopexy, Posterior repair
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Oklahoma
Pelvic Organ Prolapse
Flat Polypropylene Mesh in the Treatment of Uterine and Recurrent or Advanced Pelvic Organ Prolapse
This study is being done to evaluate the safety and feasibility of using flat polypropylene Restorelle® mesh, an ultra-lightweight mesh, for transvaginal use in surgically correcting certain specific cases of pelvic organ…
- Trial name
- NCT06225375
- Testing
- Restorelle® Flat Mesh
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Michigan Institution of Women's Health PC
Pelvic Organ Prolapse
Comparison of Mesh-Based and Mesh-Free Laparoscopic Pectopexy in Uterus-Preserving Surgery for Apical Prolapse
This retrospective cohort study compares anatomical and functional outcomes of mesh-based and mesh-free laparoscopic uterus-preserving pectopexy in women with apical pelvic organ prolapse.
- Trial name
- PectoMesh (NCT07080957)
- Testing
- Mesh-free laparoscopic uterus-preserving pectopexy, Mesh-based laparoscopic uterus-preserving pectopexy
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Havva Betül Bacak
Uterine Fibroids, Adenomyosis
Ovarian Reserve Modification After Lps Hysterectomy With Bilateral Salpingectomy
The aim of this RCT of study is to compare the standard TLH with adnexal preservation with TLH plus prophylactic bilateral salpingectomy (PBS) in terms of ovarian reserve and surgical outcomes
- Conditions
- Uterine Fibroids, Adenomyosis, Pelvic Pain, Pelvic Prolapse
- Trial name
- NCT02086344
- Testing
- PBS, TLH _adnexal preservation
- Where
- Italy
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Prolapse, Vaginal
Vaginal Native Tissues Repair for Pelvic Organ Prolapse
The aim of the study is to assess at one year the effectiveness of the vaginal patch plastron in comparison of the anterior colporraphy through a combined definition of success: anatomic and functional.
- Trial name
- TAPP (NCT03875989)
- Testing
- Anterior colporraphy, vaginal patch plastron
- Where
- 9 sites in France
- Volunteers
- 214 people
- Sponsor
- University Hospital, Limoges
Uterine Prolapse
Abdominal Versus Vaginal Hysteropexy
This study will compare the vaginal versus the abdominal approach for the management of uterine prolapse
- Trial name
- NCT03494582
- Testing
- Sacral Hysteropexy, sacrospinous Hysteropexy
- Where
- Egypt
- Volunteers
- 53 people
- Sponsor
- Ain Shams Maternity Hospital
Prolapse, Vaginal, Vaginal Vault Prolapse
Post-Hysterectomy Vaginal Length: Horizontal vs. Vertical Closure
This prospective clinical study aims to evaluate the impact of vaginal cuff closure orientation-horizontal versus vertical-on postoperative total vaginal length in patients undergoing vaginal hysterectomy combined with lateral…
- Trial name
- vagina (NCT07067645)
- Testing
- Horizontal Vaginal Cuff Closure Technique, Vertical Vaginal Cuff Closure Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Uterine Prolapse
Randomized Controlled Trial Comparing Acellular Collagen Biomesh (Pelvisoft) to Polypropylene Mesh(Pelvitex) for Sacral Colpopexy
This research protocol is a randomized controlled trial. It is being done to compare and find out the relative differences between the materials, (Pelivisoft) "natural organic mesh" to poly propylene mesh (Pelvitex) "manmade…
- Trial name
- NCT00564083
- Testing
- sacral colpopexy
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Atlantic Health System
Vaginal Prolapse
Using a Sheathed Speculum to Visualize and Access the Cervix In Women With Excessive Vaginal Tissue
The main objective of the study is to assess the effectiveness of the sheathed speculum in providing adequate visualization and access to the cervix in patients with excessive vaginal tissue.
- Trial name
- NCT01409902
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Pelvic Organ Prolapse, Abnormal Uterine Bleeding
Evaluating Artisential Laparoscopic Instruments in Gynecologic Surgery
This study evaluates the efficacy and safety of Artisential laparoscopic instruments in minimally invasive gynecologic surgery.
- Conditions
- Pelvic Organ Prolapse, Abnormal Uterine Bleeding, Mesh Augmentation, Laparoscopic Surgery
- Trial name
- MIGS-ART (NCT06050161)
- Testing
- Articulating laparoscopic instrument, Conventional laparoscopic instrument, Robotic surgical instrument
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kern Medical Center
Leiomyoma, Pelvic Organ Prolapse
The Influence of TAP Block in the Control of Postoperative Pain After Laparotomy for Gynecological Procedures
This study evaluates the influence of the transversus abdominis plane block on the intensity of postoperative pain and the concentration of proinflammatory and pain factors after hysterectomy by laparotomy.
- Conditions
- Leiomyoma, Pelvic Organ Prolapse, Abnormal Uterine Bleeding, Chronic Pain
- Trial name
- TAP (NCT04172272)
- Testing
- Systemic multimodal analgesia administered intravenously, Transversus abdominis plane block (TAP block), Combined transversus abdominis plane block (TAP block) with systemic multimodal analgesia administered intravenously
- Where
- 2 sites in Croatia
- Volunteers
- 75 people
- Sponsor
- General Hospital Pula
Vaginal Vault Prolapse, Post-Hysterectomy Vaginal Vault Prolapse
Intraperitoneal and Extraperitoneal Uterosacral Ligament Suspensions for Post-Hysterectomy Vaginal Vault Prolapse
Post-hysterectomy vaginal vault prolapse is a common pelvic floor disorder described as descent of the vaginal apex after hysterectomy.
- Conditions
- Vaginal Vault Prolapse, Post-Hysterectomy Vaginal Vault Prolapse, Prolapse, Vaginal
- Trial name
- NCT04172896
- Testing
- Intraperitoneal Uterosacral Ligament Suspension, Extraperitoneal Uterosacral Ligament Suspension
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- The Methodist Hospital Research Institute
Pelvic Organ Prolapse, Cystocele
A Randomized Controlled Trial of Permanent vs Absorbable Suture for Uterosacral Ligament Suspension
Uterosacral ligament suspension (USLS) is a commonly performed, vaginal surgery for the correction of female pelvic organ prolapse. The original description of this procedure included the use of permanent sutures.
- Conditions
- Pelvic Organ Prolapse, Cystocele, Uterine Prolapse
- Trial name
- NCT02888093
- Testing
- Absorbent suture (polydioxanone) and Permanent suture (Gore-Tex CV2)
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Joseph Kowalski
Uterine Prolapse, Cystocele
Prophylactic Antibiotic Treatment During Vaginal Repair
Prolapse of the uterus, bladder and rectum is a common condition in multiparous and/or elderly women. The number of operations for vaginal repair is increasing in Denmark, but there is no consensus or evidence found about the…
- Conditions
- Uterine Prolapse, Cystocele, Rectocele, Enterocele
- Trial name
- NCT00162604
- Testing
- Cefuroxime
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Hvidovre University Hospital
Uterovaginal Prolapse, Prolapse of Vaginal Vault After Hysterectomy
Compare Sacrospinous Fixation Versus High Uterosacral Ligament Fixation for Uterus Vaginal Prolapse III/IV
The purpose of this study is to compare the vaginal sacrospinous colpopexy and high uterosacral colpopexy in the treatment of genital prolapse grade III/IV in women with uterus.
- Conditions
- Uterovaginal Prolapse, Prolapse of Vaginal Vault After Hysterectomy, Complete Tear, Sacrospinous Ligament, Uterosacral Ligament; Rupture
- Trial name
- NCT01347021
- Testing
- sacrospinous colpopexy versus high uterosacral colpopexy
- Where
- Brazil
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo