Clinical trials: Uveitis, open to volunteers
Cytomegalovirus (CMV), Anterior Uveitis
Systemic and Topical Antiviral Control of Cytomegalovirus Anterior Uveitis: Treatment Outcomes - Trials I and II
The goal of this clinical trial is to compare antiviral treatment strategies for cytomegalovirus (CMV) anterior uveitis - a viral infection causing inflammation inside the front of the eye - in immunocompetent adults aged 18…
- Conditions
- Cytomegalovirus (CMV), Anterior Uveitis, Infectious Uveitis, CMV Infection
- Trial name
- STACCATO I/II (NCT07513623)
- Testing
- Valganciclovir, Ganciclovir (GCV)
- Where
- 6 sites in United States, Taiwan and 1 more
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Behçet's Disease, Juvenile Psoriatic Arthritis
A Study of Apremilast in Children With Oral Ulcers Associated With Behçet's Disease or Juvenile Psoriatic Arthritis
The primary objective of this study is to evaluate the long-term safety of apremilast in subjects 2 years of age or older with oral ulcers associated with Behçets disease or 5 years of age or older with active juvenile psoriatic…
- Trial name
- NCT05767047
- Testing
- Apremilast
- Where
- 7 sites in Greece, Israel and 2 more
- Volunteers
- 48 people
- Sponsor
- Amgen
Takayasu Arteritis, Behçet's Disease
Physical and Psychosocial Parameters in Takayasu Arteritis and Behçet's Disease: A Comparative Study With Healthy Controls
Systemic vasculitis refers to a group of rare diseases characterized by inflammation of blood vessel walls, which may cause ischemia and structural damage in various organs.
- Conditions
- Takayasu Arteritis, Behçet's Disease, Healthy Controls
- Trial name
- NCT07276087
- Testing
- No intervention (observational study)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- ÖZLEM NUR TOK YAMAN
Behçet's Disease
A Study of Efficacy and Safety of Hemay005 Tablets in Patients With Behçet's Disease
This is a phase 3, multi-center, randomized, placebo-controlled, double-blind, parallel-group study with an equal randomization among the Hemay005 high dose, lower dose and placebo treatment groups.
- Trial name
- NCT06145893
- Testing
- Hemay005
- Where
- 22 sites in China
- Volunteers
- 162 people
- Sponsor
- Ganzhou Hemay Pharmaceutical Co., Ltd
Spondylarthritis, Uveitis, Anterior
Observational Prospective Turkish Inception Cohort of Uveitis and Spondyloarthritis
Spondyloarthritis (SpA) encompasses a group of inflammatory rheumatic diseases characterized by axial and/or peripheral arthritis, along with extra-articular manifestations such as enthesitis, dactylitis, uveitis, and skin…
- Trial name
- OPTICUS (NCT06720376)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Marmara University
Behçet's Syndrome (BS)
Ustekinumab in BEhçet's Syndrome STudy
This non-interventional study is an observational cohort with parallel groups aiming primarily to describe the success of biosimilar of ustekinumab in Behçet's syndrome in whom conventional approaches have failed or are not…
- Trial name
- USBEST (NCT07244614)
- Where
- 11 sites in France
- Volunteers
- 208 people
- Sponsor
- Groupe français d'étude des Maladies Inflammatoires de loeil
Presumed Trematode Induced Uveitis, Uveitis
Ocular Fluid Work-up in Presumed Trematode Induced Granulomatous Uveitis
Ocular Fluid Work-up in Presumed Trematode Induced Granulomatous Uveitis
- Trial name
- NCT07885137
- Testing
- AC fluid sample, Vitreous fluid sample
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Kasr El Aini Hospital
Rheumatic Diseases, Adult Onset Still Disease
Rheumatology Patient Registry and Biorepository
To facilitate clinical, basic science, and translational research projects involving the study of rheumatic diseases.
- Conditions
- Rheumatic Diseases, Adult Onset Still Disease, Ankylosing Spondylitis, Psoriatic Arthritis
- Trial name
- NCT04402086
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Yale University
Behçet Disease
Serum EBI-3 Protein Levels in Behçet's Disease
This cross-sectional study aims to evaluate serum Epstein-Barr virus-induced gene 3 (EBI-3) protein levels in patients with Behçet's disease compared with healthy controls.
- Trial name
- NCT07845162
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pediatric Uveitis
Demographic Data and Clinical Presentation of Pediatric Uveitis
To describe and analyze the demographics, Clinical characteristics, etiology, and visual outcomes of pediatric uveitis cases attending the outpatient clinic of Ophthalmology department, Assiut University Hospital.
- Trial name
- NCT06920017
- Volunteers
- 40 people
- Sponsor
- Assiut University
Behcet Disease
Evaluation of Voice in Behcet's
Behçet's disease (BD) is a systemic inflammatory condition of unknown origin with no definite aetiopathogenetic pathways accepted worldwide.
- Trial name
- NCT06836817
- Testing
- 1-Laryngyscopic examination 2-Acoustic analysis
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Minia University
Behçet's Syndrome, Behçet's Syndrome (BS)
Corticotropin for Behçet's Disease: A Multicenter Randomized Controlled TrialAcronym.
Adrenocorticotropic hormone (ACTH) is a polypeptide hormone secreted by the anterior pituitary gland. It can stimulate adrenal cortical hyperplasia and the secretion of glucocorticoids, thereby exerting anti-inflammatory…
- Trial name
- NCT07833163
- Testing
- Repository Corticotropin Injection (ACTH)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University People's Hospital
Anterior Uveitis (AU), Birdshot Chorioretinitis
Quantification & Classification of Inflammatory Cells in Uveitis Using OCT
The goal of this study is to determine if it's possible to use a high resolution imaging device called optical coherence tomography (OCT) to develop an unbiased, standard method of counting and categorizing the various types of…
- Conditions
- Anterior Uveitis (AU), Birdshot Chorioretinitis, Behcet Disease, Herpes Simplex Virus
- Trial name
- NCT07065747
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Behcet Syndrome
Randomized Controlled Multicenter Study Comparing Steroid Therapy Plus Anticoagulants to Steroid Therapy Alone in Deep Venous Thrombosis of Behçet's Syndrome
In patients with Behçet's syndrome (BS), deep venous thrombosis (DVT) is thought to result from inflammation of the vessel wall rather than hyper coagulability.
- Trial name
- ACTOR (NCT06780462)
- Testing
- Corticosteroids + Rivaroxaban, Corticosteroids alone
- Where
- 17 sites in France
- Volunteers
- 134 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Active Non-anterior, Non-infectious Uveitis
A Phase II Clinical Trial to Evaluate the Efficacy and Safety of FXS5626 in Patients With NIU
The purpose of this study is to find out the efficacy and safety of oral FXS5626 in participants with active, non-anterior (intermediate, posterior, or pan) non-infectious uveitis (NIU).
- Trial name
- NCT07552012
- Testing
- FXS5626 tablet
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.
Uveitis
RChildUV:Study on Non-infectious Chronic Uveitis in Pediatric Age
Uveitis is an inflammatory disease of the uvea, one of the highly vascularized fundamental structures of the eye. It is a rare condition in children, with an incidence in the pediatric population ranging from 2% to 14% of all…
- Trial name
- NCT06273748
- Where
- 19 sites in United States, Belgium and 3 more
- Volunteers
- 290 people
- Sponsor
- Meyer Children's Hospital IRCCS
Uveitis
A Study of Efficacy and Safety of GenSci048 in Subjects With Active Uveitis.
This study is designed to evaluate the efficacy and safety of GenSci048 compared with placebo in subjects with active non-infectious uveitis.
- Trial name
- NCT07547995
- Testing
- GenSci048
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Noninfectious Posterior Uveitis, Uveitis, Posterior
Frequency and Intensity of Inflammatory Relapses in Patients With Non-infectious Posterior Uveitis Treated With a Fluocinolone Acetonide Implant
Non-infectious posterior uveitis is a chronic inflammatory eye disease that can lead to irreversible retinal damage and visual impairment due to repeated inflammatory relapses.
- Conditions
- Noninfectious Posterior Uveitis, Uveitis, Posterior, Uveitic Macular Edema
- Trial name
- FIRE (NCT07423442)
- Testing
- fluocinolone acetonide intravitreal implant
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Nantes University Hospital
Ankylosing Spondylitis (AS) / Radiographic Axial SpA (r-axSpA), Non-radiographic Axial Spondyloarthritis (Nr-axSpA)
Chinese Spondyloarthritis Inception Cohort (CESPIC)
The Chinese Spondyloarthritis Inception cohort (CESPIC) was started 2000 as a prospective, longitudinal, multicentre, nationwide study in China on patients with early SpA including ankylosing spondylitis (AS, also known as…
- Conditions
- Ankylosing Spondylitis (AS) / Radiographic Axial SpA (r-axSpA), Non-radiographic Axial Spondyloarthritis (Nr-axSpA), Axial Psoriatic Arthritis (axPsA), Acute Anterior Uveitis (AAU)
- Trial name
- CESPIC (NCT05960864)
- Testing
- Celecoxib
- Volunteers
- 1,000 people
- Sponsor
- Southwest Hospital, China
Behcet Disease and Vascular Involvement
Clinical, Biochemical and Epigenetic Profile of Pediatric Behçet Disease
Behçet disease (BD) is a chronic multisystem inflammatory disorder with a relapsing-remitting course. Pediatric-onset BD is rare and characterized by marked clinical heterogeneity, frequent incomplete presentation at disease…
- Trial name
- PED-BD (NCT07375940)
- Testing
- Biomarker analysis of blood samples
- Where
- 2 sites in Italy, United Kingdom
- Volunteers
- 90 people
- Sponsor
- Meyer Children's Hospital IRCCS