Clinical trials: VALİDİTY
Substance Withdrawal Syndrome
Efficacy of XYZ for Withdrawal Syndrome
This is a randomized controlled clinical trial to explore the efficacy and mechanism of Tiaozhong-Yiqi Decoction (TZYD) in treating substance withdrawal syndrome, combining network pharmacology analysis and clinical validation.
- Trial name
- TZYT-WS (NCT07543809)
- Testing
- Tiaozhong-Yiqi Decoction, routine care
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Chongqing Jiangbei Hospital of Traditional Chinese Medicine
Small Cell Lung Cancer
Development and Validation of Nomogram Predicting Survival in Chinese SCLC Patients
In this retrospective study, patients diagnosed with SCLC between January 2011 to September 2022 were identified from database of the Second Hospital of Shandong University.
- Trial name
- NCT05673798
- Testing
- initial chemotherapy response
- Volunteers
- 569 people
- Sponsor
- The Second Hospital of Shandong University
Apple Watch
Smart Watch, Heart Rate and So2 in Cardiac Patients
Background: Apple Watch validity to measure the heart rate (HR) and oxygen saturation (Spo2) in healthy subjects has been investigated, but its accuracy and validity for patients with cardiac diseases is still unclear.
- Trial name
- NCT05199844
- Testing
- Apple Watch
- Where
- Saudi Arabia
- Volunteers
- 260 people
- Sponsor
- Umm Al-Qura University
Spinal Cord Diseases
Pilot Trial of a System for Motor Function Recovery
This is a multi-center, prospective, blinded, pilot feasibility study to evaluate improvement in sensory and motor function with sham.
- Trial name
- NCT04683471
- Testing
- Stimulator
- Where
- 3 sites in United States
- Volunteers
- 12 people
- Sponsor
- Niche Biomedical, Inc. dba ANEUVO
Cardiovascular Diseases, Atherosclerosis
The AI-CAC Model for Subclinical Atherosclerosis Detection on Chest X-ray
The AI-CAC model is an artificial intelligence system capable of assessing the presence of subclinical atherosclerosis on a simple chest radiograph.
- Conditions
- Cardiovascular Diseases, Atherosclerosis, Coronary Artery Calcification
- Trial name
- AI-CAC-PVS (NCT06301009)
- Testing
- AI-CAC score
- Volunteers
- 500 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Compartment Syndromes
SWISS_EVIDENCE - Compartment Compressibility Monitoring Using CPM#1
Compartment syndrome is a very serious musculoskeletal disorder, which can lead to potentially devastating consequences, such as limb amputation and life-threatening conditions.
- Trial name
- NCT05367921
- Testing
- Measurement of compartment compressibility
- Where
- Switzerland
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Compremium AG
DDD, Deformity
MaxAn Post Market Surveillance Validation
This study is being performed to document the outcomes of subjects using our MaxAn Anterior Cervical Plate and assess them for Adjacent level Disease. All subjects will be followed for 2 years.
- Conditions
- DDD, Deformity, Tumor, Fracture
- Trial name
- MaxAn (NCT01343693)
- Where
- 6 sites in United States
- Volunteers
- 119 people
- Sponsor
- Zimmer Biomet
COVID-19, Severe Respiratory Distress Syndrome
suPAR Michigan M2C2 Heterogeneity Validation Cohort Study
This is a retrospective, non interventional cohort study using stored plasma samples from appoximately 300 adults hospitalized with confirmed COVID 19.
- Conditions
- COVID-19, Severe Respiratory Distress Syndrome, Acute Respiratory Distress Syndrome
- Trial name
- NCT07466524
- Testing
- suPARnostic® TurbiLatex Assay on Roche cobas c501
- Where
- United States
- Volunteers
- 367 people
- Sponsor
- ViroGates A/S
Intestinal Obstruction
Prospective Multicenter Validation of a Severity Score of Strangulated Small Bowel Occlusion
The purpose of this study is to apply and validate a clinicoradiological score for the prediction of severity of strangulated small bowel occlusion (SBO).
- Trial name
- NCT01125280
- Testing
- Conservative treatment versus surgical treatment
- Where
- Switzerland
- Volunteers
- 300 people
- Sponsor
- University Hospital, Geneva
Hyperkyphosis
Development and Validation of MPF to Prevent and Mitigate Postural Hyperkyphosis in Postmenopausal Women
Postural hyperkyphosis is common in postmenopausal women and leads to spinal dysfunction, pain, impaired balance, and increased fall risk.
- Trial name
- NCT07068360
- Testing
- Strength Training +Postural Correction Exercises + Balance Training +Flexibility Exercises, Standard Intervention (Control Group)
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- Superior University
Idiopathic Parkinson Disease, Dyskinesias
Reliability and Validity Study of the Turkish Version of the Parkinson's Disease Dyskinesia Scale (PDYS-26)
The aim of this methodological study was to investigate the Turkish validity and reliability of the Parkinson's Disease Dyskinesia Scale (PDYS-26).The scale evaluates choreic dyskinesia.Measures the impact of dyskinesia on…
- Conditions
- Idiopathic Parkinson Disease, Dyskinesias, Quality of Life
- Trial name
- NCT07023224
- Testing
- Turkish version of the Parkinson's Disease Dyskinesia Scale (PDYS-26)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Izmir Bakircay University
HIP AND KNEE OSTEOARTHRITIS
Prepare II - Predictive Model Training and External Validation
The general aim of the project is training and testing a predictive model of inpatient rehabilitation stay after hip and knee replacement for osteoarthritis.
- Trial name
- NCT07304323
- Testing
- Functional rehabilitation
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Leg Ulcer, Diabetic Foot Ulcer
Proof of Concept (Design Validation) in Patient With Hard to Heal Wounds Such as Pressure Ulcer, Diabetic Foot Ulcer and Leg Ulcer, Leia
The purpose of this reseach study is to determine Mölnlycke Health Care´s Leia dressing performance properties is fulfilled and that the dressing is safe when used on wound types such as pressure ulcer, leg ulcer, and diabetic…
- Conditions
- Leg Ulcer, Diabetic Foot Ulcer, Pressure Ulcer
- Trial name
- NCT01966380
- Testing
- Leia
- Where
- Sweden
- Volunteers
- 6 people
- Sponsor
- Molnlycke Health Care AB
Bone Age
The Validity of Bone Age Assessment by an Ultrasound Apparatus (SonicBone)
Bone age assessment is currently an important tool in final height implication in children. It is an important tool in the phases of investigation and treatment of short stature, tall stature, pubertal timing and various…
- Trial name
- NCT01346618
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assaf Harofeh MC
Covid19
Reliability and Validity of the Turkish Version of SMİLE-C
How the life style changed multidimensionally with home isolation in the period of COVID-19 is a new research question. Physical and social isolation, home isolation, and quarantine policies applied during epidemic periods such…
- Trial name
- SMİLE-C (NCT04894279)
- Where
- Turkey (Türkiye)
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Marmara University
Temporomandibular Disorder
Turkish Validity and Reliability of The Helkimo Index for Diagnosis of Temporomandibular Disorders
Helkimo Index evaluates movement, joint function, pain and musculature, providing a quick general overview that could be very useful at different levels of care.
- Trial name
- NCT05749224
- Testing
- Helkimo Index
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
HIV-1 Infected Patients, Fold-change Resistance
GePheRal: Clinical Validation of the Genotypic Diagnosis of Hiv-1 Resistance to Raltegravir by Parallel Analysis of the Genotype and Phenotype Profiles of Resistance
The purpose of this study is to correlate the different patterns of resistance mutations observed in vivo in patients failing RAL treatment with the fold-change resistance determined by the phenotypic assay.
- Conditions
- HIV-1 Infected Patients, Fold-change Resistance, Resistance Mutations
- Trial name
- NCT01381328
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Università Vita-Salute San Raffaele
Temporomandibular Disorder, Children, Only
DC/TMD Axis I for Children
The aim of the present investigation was to perform the content and construct validation of the diagnostic criteria for TMD (DC/TMD) Axis I, for children 7 to 11 years old.
- Conditions
- Temporomandibular Disorder, Children, Only, Pain Disorder, Joint Disorder, Temporomandibular
- Trial name
- NCT04256811
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- CES University
Hand Injuries, Forearm Injuries
Reliability and Validity of the Tampa Scale for Kinesiophobia
The aim of this study was to investigate the validity and reliability of the Tampa Scale for Kinesiophobia (TSK) in patients with traumatic hand and forearm injuries.
- Conditions
- Hand Injuries, Forearm Injuries, Trauma
- Trial name
- NCT05878509
- Testing
- conducting questionnaires, assesment of the severity and pain
- Where
- Turkey (Türkiye)
- Volunteers
- 170 people
- Sponsor
- Pamukkale University
Lung Cancer
Determination and Validation of a Multi-analyte Assay for Lung Cancer Screening
This study is part of the development and validation of a non-invasive lung screening test which aim to identify early stage lung cancer in patients at high risk for lung cancer.
- Trial name
- NCT04968548
- Testing
- Blood collection
- Where
- 31 sites in United States, Canada
- Volunteers
- 6,182 people
- Sponsor
- Nucleix Ltd.
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