Clinical trials: VATS
Non Small Cell Lung Cancer
Pemetrexed Plus Oxaliplatin as Adjuvant Chemotherapy for Radically Resected Non-Small Cell Lung Cancer
The main purpose of this phase II trial is to evaluate the clinical feasibility-in terms of patients without dose limiting toxicities or premature treatment withdrawal or death-of administering adjuvant chemotherapy of pemetrexed…
- Trial name
- NCT00923637
- Testing
- Pemetrexed/Oxaliplatin
- Where
- China
- Volunteers
- 75 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Postoperative Pain Management
Ultrasound-Guided Erector Spinae Plane Block Versus Intravenous Nalbuphine
2.1. Study population and setting: This prospective, randomized, controlled clinical trial will be conducted at the thoracic surgery operation room, cardiothoracic surgery building, Zagazig University Hospitals, from July 2025 to…
- Trial name
- VATS (NCT07391475)
- Testing
- Erector Spinae (ESP) Block with Bupivacaine (Marcaine®)
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Zagazig University
Sex Differences, Postoperative Sleep Quality
Sex Differences in Postoperative Sleep Quality and Inflammation
Video-Assisted Thoracoscopic Surgery(VATS) is among the most common and disabling persistent pain and inflammation conditions, with increasing prevalence in the developed world, and affects women to a greater degree than men.
- Conditions
- Sex Differences, Postoperative Sleep Quality, Postoperative Pain, Inflammation Function
- Trial name
- NCT04608435
- Testing
- Video-Assisted Thoracoscopic Surgery
- Where
- China
- Volunteers
- 213 people
- Sponsor
- Shengjing Hospital
Cryotherapy Effect, Chronic Pain
Intercostal Cryoanalgesia for Chronic Pain After VATS Lung Resection
Intercostal cryoanalgesia is a technique that allows extensive and prolonged analgesia of the hemithorax. The aim of this study is to demonstrate the efficacy of intercostal cryoanalgesia as an adjunct to a single-injection…
- Conditions
- Cryotherapy Effect, Chronic Pain, Lung Cancer, Surgery
- Trial name
- CRYO-VATS-2 (NCT05884099)
- Testing
- Cryoanalgesia AND single-injection paravertebral block, Single-injection paravertebral block
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Post Operative Pain, Thoracic Cancer
Thoracic Paravertebral Block With Methylene Blue Visual Confirmation for Postoperative Pain After VATS Lobectomy
The goal of this study is to compare the efficacy in controlling postoperative pain of paravertebral block (PVB) with methylene blue visual confirmation and thoracic epidural anesthesia (TEA).
- Trial name
- NCT05812521
- Testing
- Paravertebral block with methylene blue, Thoracic Epidural Anesthesia
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- University of Campania Luigi Vanvitelli
Systemic Inflammatory Response Syndrome, Postoperative Pain, Acute
Opioid Free Anaesthesia-Analgesia Strategy on Surgical Stress and Immunomodulation in Elective VATS-Lobectomy for NSCLC
Lobectomy is a major, high-risk surgical procedure that in addition to one-lung ventilation (OLV) exerts a potent surgical stress response.
- Conditions
- Systemic Inflammatory Response Syndrome, Postoperative Pain, Acute, Postoperative Pain, Chronic, Infections Postoperative
- Trial name
- NCT05172739
- Testing
- Opioid-Based Anesthesia-Analgesia Strategy, Opioid-free Anesthesia-Analgesia Strategy
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- University of Crete
Lidocaine, Dexmedetomidine
Lidocaine and Dexmedetomidine Infusion and Their Combination on Perioperative Pain in Patients Undergoing Video-Assisted Thoracoscopic Surgery
This study aims to compare lidocaine and dexmedetomidine infusion and their combination on perioperative pain in patients undergoing video-assisted thoracoscopic surgery.
- Conditions
- Lidocaine, Dexmedetomidine, Infusion, Perioperative Pain
- Trial name
- NCT06837519
- Testing
- Lidocaine, Dexmedetomidine, Lidocaine and Dexmedetomidine
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Ain Shams University
Early Stage Non-small-cell Lung Cancer (Stage 1-2)
Assessment of Ergonomics in 3D vs 2D Thoracoscopic Lobectomy
Video-assisted thoracic surgery (VATS) pulmonary lobectomy is currently widely employed as the first treatment option for surgical management of early stage (stage I-II) non-small-cell-lung-cancer (NSCLC).
- Trial name
- NCT03925103
- Testing
- 3D VATS lobectomy, 2D VATS lobectomy
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- University of Rome Tor Vergata
Pleural Effusion, Malignant, Pleural Mesothelioma
A Comparative Study Between Regional Anesthesia in Thoracoscopes and the Conventional General Anesthesia
Video-assisted thoracic surgery (VATS) is usually performed with general anesthesia and single lung ventilation. However, performing thoracic surgery under awake regional anesthesia has several potential advantages including…
- Conditions
- Pleural Effusion, Malignant, Pleural Mesothelioma, Pleural Empyema, Pulmonary Diseases or Conditions
- Trial name
- VATS (NCT05077111)
- Testing
- Thoracic Epidural Anesthesia, General Anesthesia with One Lung Ventilation
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mohamed Reda Ashour
Chagas Cardiomyopathy, Ventricular Arrythmia
Sympathetic Denervation by Video-assisted Thoracoscopy in Control of Cardiac Arrhythmias in Patients With Chagas Disease
Ventricular tachycardia (VT) is the main cause of sudden death in patients with structural heart diseases. The use of ICD (implantable cardio-defibrillator) could prevent sudden death, however, the occurrence of repetitive shock…
- Trial name
- NCT04239144
- Testing
- Bilateral sympathectomy, Catheter ablation
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- University of Sao Paulo General Hospital
Pain, Postoperative
Post- Thoracotomy Paravertebral Block
Postoperative pain is the most undesired consequence of surgery, and if not managed adequately, can lead to delayed recovery and increased hospital stay.
- Trial name
- NCT02886429
- Testing
- Bupivacaine, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Lung Diseases
Continuous Erector Spinae Plane Block or Thoracic Epidural Analgesia Following Video Assisted Thoracic Surgery
Video assisted thoracic surgery (VATS) has recently been evaluated as the standard surgical procedure for lung surgery. Although VATS is less painful than thoracotomy, patients may feel severe pain during the first hours at…
- Trial name
- NCT03960736
- Testing
- ESP block (Group A), TEA group (Group B)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Medipol University
Lung Cancer
Comparison of the Duration of Ropivacaine Combined With Dexmedetomidine or Dexamethasone on Paravertebral Block
This study was a prospective, randomized, controlled, and double-blind trial. Major assessments were made during the operation and 48 h postoperatively.
- Trial name
- NCT03570645
- Testing
- Dexmedetomidine Group, dexamethasone group, control group
- Where
- China
- Volunteers
- 154 people
- Sponsor
- China Medical University, China
Pulmonary Neoplasm
Robot-assisted vs VATS Lobectomy for NSCLC
Robot-assisted thoracoscopic surgery (RATS) was widely used in thoracic surgery, the surgical safety and feasibility of RATS lobectomy for NSCLC has been confirmed.
- Trial name
- RVlob (NCT03134534)
- Testing
- VATS lobectomy, RATS lobectomy
- Where
- China
- Volunteers
- 320 people
- Sponsor
- Ruijin Hospital
Musculoskeletal Diseases or Conditions
ITPB 1 vs 3 in VATS
This study aims to evaluate the quality of recovery after video-assisted thoracoscopic surgery (VATS) by comparing the efficacy of a single-level intertransverse process block (ITPB) against a three-level ITPB, with particular…
- Trial name
- NCT06838793
- Testing
- Single Level Intertransverse Process Block, Three Level Intertransverse Process Block
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- Chinese University of Hong Kong
Post Operative Pain, Acute, Post-Op Complication
Pigtail or Chest Tube Placement After Uniportal Video-assisted Thoracoscopic Surgery
This study aims to figure out how small-bore pigtail catheter or large-bore chest tube for postoperative drainage impact on analgesic efficacy and actually enhance recovery postoperatively.
- Conditions
- Post Operative Pain, Acute, Post-Op Complication, Opioid Use, Unspecified, ERAS
- Trial name
- NCT06050551
- Testing
- uniportal VATS
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Cheng-Kung University Hospital
Postoperative Pain, Thoracic Surgery
Intravenous Lidocaine, Ketamine, and Magnesium in Thoracic Surgery
Thoracic surgery often produces severe postoperative pain due to nerve injury and inflammation. Effective pain control is essential to reduce complications and opioid use.
- Conditions
- Postoperative Pain, Thoracic Surgery, Multimodal Analgesia, Opioid Consumption, Postoperative
- Trial name
- LKM-Thorax (NCT07359469)
- Where
- Spain
- Volunteers
- 118 people
- Sponsor
- Universidad Pública de Navarra
Video-assisted Thoracic Surgery (VATS)
Serum Bupivacaine Concentration Levels After Intermittent Bolus Injections Via Erector Spinae Plane Peripheral Catheter
The purpose of this study is to evaluate the serum bupivacaine concentrations over time after 0.125% bupivacaine is deposited every 6 hours in the erector spinae plane in patients who undergo unilateral VATS.
- Trial name
- NCT05038956
- Where
- United States
- Sponsor
- University of Utah
Mediastinal Nodes
Application Study of 12G Pigtail Catheter Used for Post-operative Drainage After Thoracoscopic Surgery for Mediastinal Nodes
Pigtail catheter(PC) has been used for thoracic drainage in the patients with pneumothorax or traumatic hemothorax/hemopneumothorax, and some study indicated that PC could obtain similar outcomes when comparing with chest…
- Trial name
- NCT03743389
- Testing
- 12G pigtail catheter, 16F chest tube
- Volunteers
- 80 people
- Sponsor
- Tongji Hospital
Video-assisted Thoracoscopic Lung Surgery；Anesthesia
Opioid-Free Combined Anesthesia With Spontaneous Breathing for VATS
Non-tracheal intubated combined anesthesia with preserved spontaneous breathing significantly enhances the quality and speed of recovery post-VATS for patients undergoing lung nodule surgery.
- Trial name
- NCT06367218
- Testing
- opioid based strategy, opioid-free strategy, Laryngeal mask airway; Preserved spontaneous breathing
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Tongji Hospital