Clinical trials: VATS Lobectomy
Lung Cancer, Complication of Surgical Procedure
Comparison of LigaSure to Conventional Electrocoagulation in Video-assisted Thoracoscopic Surgery Lobectomy
Surgical treatment of lung cancer consists of two elements: anatomical lung resection (segmentectomy, lobectomy or pneumonectomy) followed by mediastinal lymph node dissection (MLND).
- Trial name
- NCT03125798
- Testing
- LigaSure™, Monopolar electrocautery
- Where
- Poland
- Volunteers
- 216 people
- Sponsor
- Wielkopolskie Centrum Pulmonologii i Torakochirurgii
Post-thoracotomy Pain Syndrome
IMPACT OF OPERATIVE POSITIONING ON THE DEVELOPMENT OF SHOULDER PAIN AFTER PULMONARY LOBECTOMY BY VATS
The investigators want to be able to show a 66% decrease in the incidence of shoulder pain in the "support" group compared to the "suspension" group.
- Trial name
- POVA (NCT04415242)
- Testing
- positioning
- Where
- Canada
- Volunteers
- 134 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec
Lung Cancer
Postoperative Pain After Single Port, Two Ports and Three Ports VATS Lobectomy
This single-center, prospective, randomized controlled trial was designed to assess and compare the postoperative pain after VATS lobectomy performed though one, two and three incisions.
- Trial name
- NCT03228056
- Testing
- pain intensity measured in VAS scale
- Where
- 2 sites in Poland
- Volunteers
- 90 people
- Sponsor
- Pulmonary Hospital Zakopane
Non-small Cell Lung Cancer
Assisted-VATS Sleeve Lobectomy for Non-small Cell Lung Cancer
The purpose of this study is to examine the feasibility of assisted-VATS (video-assisted thoracoscopic surgery) sleeve lobectomy for non-small cell lung cancer for non-small cell lung cancer.
- Trial name
- VATS (NCT00997724)
- Testing
- a-VATS
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Video-Assisted Thoracic Surgery, Lung Cancer
Curative Effect and Quality of Life Between Uniportal and Open Sleeve Lobectomy for Central Type Lung Cancer
In surgical treatment decisions, locally advanced central lung cancer is the most difficult. When infiltrating into the trachea, conventional pneumonectomy cannot achieve the purpose of radical treatment.Pulmonary sleeve…
- Trial name
- NCT03523468
- Testing
- uniportal sleeve lobectomy, open sleeve lobectomy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Lei Jiang
Non-small Cell Lung Cancer
Suction on Post-Operative Chest Tubes
The level of suction on post-operative chest tubes after video-assisted thoracoscopic surgery (VATS) lobectomy for lung cancer has previously shown to affect duration of drainage.
- Trial name
- SPOCT (NCT02911259)
- Testing
- Suction is set to -2 cmH2O, Suction is set to -10 cmH2O
- Where
- Denmark
- Volunteers
- 230 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Lung Cancer, Thoracic Surgery, Video-Assisted
3D Lung Reconstructions Using Open-source Software for Lung Cancer Surgery
Preoperative three-dimensional (3D) lung reconstructions can reduce intraoperative blood loss, conversion rate, and operation duration.
- Conditions
- Lung Cancer, Thoracic Surgery, Video-Assisted, Lobectomy, Segmentectomy
- Trial name
- 3D-LUNG (NCT06132607)
- Where
- Netherlands
- Volunteers
- 13 people
- Sponsor
- Erik de Loos
Lung Cancer
Pulmonary Artery Harmonic Ace+7 Energy Sealing in VATS Lobectomy
Video-assisted thoracic surgery (VATS) anatomical lung resection provides an effective minimally invasive treatment strategy for stage I and II lung cancer.
- Trial name
- NCT02652286
- Testing
- HARMONIC ACE+7
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Lung Cancer
Modified Video-assisted Thoracoscopic Surgery (VATS) Lobectomy for Early-stage Non-small Cell Lung Cancer (NSCLC)
The purpose of this study is to modify the surgical technique of VATS (video-assisted thoracoscopic surgery) lobectomy for early-stage non-small cell lung cancer.
- Trial name
- NCT01337037
- Testing
- VATS lobectomy using modified equipments, VATS lobectomy using less staples, Standard VATS lobectomy
- Where
- 14 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Peking University People's Hospital
Lung Neoplasms, Postoperative Pain
Prospective Randomized Trial Comparing the Effectiveness of Continuous Paravertebral Infusion of Local Anesthetics Versus Intravenous Patient-controlled Analgesia on Acute and Chronic Neuropathic Pain After VATS Lobectomy
Since mid-2000, thoracoscopic lobectomy has been replaced with conventional open lobectomy and it has reduced the operative morbidities and mortalities.
- Trial name
- NCT01703351
- Testing
- 0.5% ropivacaine, Fentanyl 500mcg + acupan 160mg + nasea 0.6mg
- Where
- South Korea
- Volunteers
- 79 people
- Sponsor
- Yonsei University
Lung Cancer
Treatment of Early Stage Lung Cancer by VATS Versus OPEN Lobectomy
In patients with early stage lung cancer surgical lobectomy is the treatment of choice. A resection by Video-assisted Thoracic Surgery (VATS) is probably superior to an open procedure by thoracotomy for patients with early stage…
- Trial name
- SCOPE (NCT01933828)
- Testing
- OPEN lobectomy, VATS lobectomy, ROBOT-assisted lobectomy
- Where
- Netherlands
- Volunteers
- 176 people
- Sponsor
- Radboud University Medical Center
Pain, Postoperative
Preventing pAIn With NMDA Antagonists - Steroids in Thoracoscopic lObectomy Procedures (PAIN-STOP) Pilot Trial
The objective of the PAIN-STOP trial is to assess the feasibility of a larger randomized controlled trial (RCT) evaluating NMDA antagonists and IV steroids, as compared to placebo, in decreasing the chances of clinically…
- Trial name
- PAIN-STOP (NCT02950233)
- Testing
- NMDA active, Steroid active
- Where
- 2 sites in United States, Canada
- Volunteers
- 27 people
- Sponsor
- Population Health Research Institute
Lung Cancer
VATS Versus Open Pulmonary Lobectomy in the Limelight of OEP
The standard operative approach to pulmonary lesions has been via postero-lateral thoracotomy and direct vision. This technique has some advantages but its morbidity is significant.
- Trial name
- VOLO (NCT02910453)
- Testing
- Pulmonary lobectomy
- Where
- Italy
- Volunteers
- 78 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Lung Neoplasms, Pain
Supplementary Epidural Analgesia in Video-Assisted Thoracic Surgery (VATS) - The SEAVATS Study
Whereas it, in the case of conventional thoracotomy, has been demonstrated that thoracic epidural analgesia is more effective than systemic opioids in terms of pain relief and preservation of postoperative pulmonary function, the…
- Conditions
- Lung Neoplasms, Pain, Immune Suppression
- Trial name
- SEAVATS (NCT02359175)
- Testing
- Bupivacaine in epidural catheter, Fentanyl in epidural catheter, Oral Paracetamol
- Where
- Denmark
- Volunteers
- 161 people
- Sponsor
- Odense University Hospital
Video-assisted Thoracic Surgery
Effect of the PIEB Versus CEI on the Quality of Postoperative Recovery in Patients Undergoing VATS Lobectomy
In recent years, lobectomy under VATS(Video-assisted thoracic surgery,VATS) has gradually emerged, but there is still a proportion of patients with postoperative pain that affects their postoperative recovery.
- Trial name
- NCT05930405
- Testing
- programmed intermittent epidural bolus, continuous epidural infusion
- Where
- China
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Non-Small Cell Lung Cancer, Postoperative Air Leak
Progel Platinum for Air Leak Reduction After VATS Lobectomy for NSCLC
This multicenter randomized trial evaluates whether routine use of Progel Platinum surgical sealant on stapled fissure lines during VATS upper or lower lobectomy for NSCLC reduces pleural drainage duration compared with standard…
- Conditions
- Non-Small Cell Lung Cancer, Postoperative Air Leak, NSCLC
- Trial name
- E-SEAL (NCT07479277)
- Testing
- Progel Platinum, Mechanical Stapling
- Where
- 6 sites in Italy
- Volunteers
- 160 people
- Sponsor
- Fondazione del Piemonte per l'Oncologia
Lung Cancer
Randomized Study on Effects of Uniportal VATS Versus Triportal VATS
For the treatment of stage I-II NSCLC, two mini-invasive techniques are mostly utilized: uni-portal and three-portal VATS. In the uniportal approach, the injury on a single intercostal space could determine a lower level of pain…
- Trial name
- NCT03240250
- Testing
- VATS uni-portal lobectomy and lymphoadenectomy, VATS three-portal lobectomy and lymphoadenectomy
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Video-assisted Thoracoscopic Surgery (VATS), Loxoprofen Sodium Patch
The Efficacy and Safety of Loxoprofen Sodium Patch in Relieving Postoperative Pain After Thoracoscopic Surgery
Video-assisted thoracoscopic surgery (VATS) is less invasive compared to traditional thoracotomy, but it is still reported that the incidence of acute pain following VATS exceeds 80%.
- Conditions
- Video-assisted Thoracoscopic Surgery (VATS), Loxoprofen Sodium Patch, Local Incision, Postoperative Pain
- Trial name
- NCT07591220
- Testing
- Loxoprofen Sodium Patch on the incision site, Loxoprofen Sodium Patch on the contralateral side
- Volunteers
- 156 people
- Sponsor
- Beijing Tiantan Hospital
Lung Surgery, Enhanced Recovery After Surgery, ERAS
Evaluation of the Effectiveness of Enhanced Recovery After Surgery (ERAS) Program in Pediatric Lung Surgery
This study aims to evaluate the clinical effectiveness of the Enhanced Recovery After Surgery (ERAS) program for pediatric lung surgery at our institution.
- Conditions
- Lung Surgery, Enhanced Recovery After Surgery, ERAS, Pediatric
- Trial name
- NCT07241286
- Testing
- Enhanced Recovery After Surgery, ERAS
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Carcinoma, Non-Small-Cell Lung
ELobectomy for NSCLC by VATS Versus Thoracotomy (ECTOP-1007)
This study is one of Eastern Cooperative Thoracic Oncology Projects (ECTOP-1007). The goal of this study is to determine video-assisted thoracoscopic surgery is non-inferior to thoracotomy in terms of disease-free survival for…
- Trial name
- NCT03786003
- Testing
- VATS, Thoracotomy
- Where
- China
- Volunteers
- 1,086 people, healthy volunteers welcome
- Sponsor
- Fudan University