Clinical trials: VV ECMO
Critical Illness
Effect of Different VV ECMO Flows on Lung Perfusion Monitored by EIT
The purpose of this study is to investigate the feasibility of using electric impedance tomography (EIT) to monitor lung perfusion during veno-venous (VV) extracopreal membrane oxygenation (ECMO) support, as well as the effect of…
- Trial name
- NCT05778292
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Extracorporeal Membrane Oxygenation Complication, Hemorrhage
Platelets and Extracorporeal Membrane Oxygenation Veno-venous
In severe lung or heart disease, ExtraCorporeal Membrane Oxygenation (ECMO) may be used temporarily and can be responsible for major haemorrhagic complications. Thrombocytopenia and possibly thrombopathy promote bleeding.
- Conditions
- Extracorporeal Membrane Oxygenation Complication, Hemorrhage, Blood Platelet Disorder, Thrombosis
- Trial name
- PLAT-VV-ECMO (NCT07580469)
- Testing
- blood draws
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Toulouse
Pulmonary Hypertension of the Newborn (PPHN)
Circulatory Changes During Venovenous (VV)- and Venoarterial (VA) Extracorporeal Membrane Oxygenation (ECMO)
Rationale: Persistent pulmonary hypertension of the newborn (PPHN) is a life threatening disease with a high mortality rate. Extracorporeal Membrane Oxygenation (ECMO) with veno-arterial (V-A) or veno-venous (V-V) cannulation can…
- Trial name
- ECMO (NCT00622492)
- Testing
- echocardiography Doppler sonography, blood and urine sampling
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Radboud University Medical Center
Acute Respiratory Failure, ECMO
Cardinality Matching Study of Early v.s. Delayed VV ECMO in Severe Respiratory Failure
Clinical reasoning and recent data suggest that early use of venovenous extracorporeal membrane oxygenation in refractory respiratory failure may confer a survival advantage.
- Trial name
- NCT03981393
- Volunteers
- 667 people
- Sponsor
- University of Cambridge
VV-ECMO, Thoracic Surgery
Prognosis of Veno-Venous Extracorporeal Membrane Oxygenation in Emergency Thoracic Surgery
Veno-vneous extracorporeal membrane oxygenation (VV-ECMO) is an established support strategy for acute respiratory failure, but its role in the perioperative management of emergency thoracic surgery remains poorly defined.
- Conditions
- VV-ECMO, Thoracic Surgery, Emergency Surgery, ARDS
- Trial name
- PECUR (NCT07016685)
- Where
- France
- Volunteers
- 380 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Refractory Respiratory Failure
Intravenous Continuous LMWH Seems to be Safe Alternative to UFH in VV ECMO Patients
Unfractionated heparin (UFH) is worldwide anticoagulation used and recommended anticoagulation in patients with ECMO support. However, it is accompanied with incidence of bleeding or thrombotic compliaction at about 40-60% and…
- Trial name
- NCT06010446
- Testing
- No intervention, just retrospective analysis of data.
- Where
- Czechia
- Volunteers
- 43 people
- Sponsor
- University Hospital, Motol
Extracorporeal Membrane Oxygenation Complication, Transfusion Related Complication
PRospective Multicenter Observational Study on Transfusion Practice in Vv-ECMO Patients: The PROTECMO Study
Background: Over the past decade, the use of extracorporeal membrane oxygenation (ECMO) for respiratory support in adults has increased.
- Conditions
- Extracorporeal Membrane Oxygenation Complication, Transfusion Related Complication, Hemorrhage, Anticoagulant-induced Bleeding
- Trial name
- PROTECMO (NCT03815773)
- Where
- Italy
- Volunteers
- 656 people
- Sponsor
- The Mediterranean Institute for Transplantation and Advanced Specialized Therapies
ECMO Treatment, ARDS
Hemodynamic Monitoring and Fluid Responsiveness in Venovenous Extracorporeal Membrane Oxygenation (VV ECMO) - "HemodynamECMOnitoring-VV Study"
In extracorporeal membrane oxygenation (ECMO), blood is drawn out of the body via tubes, oxygenated in an artificial lung; and then pumped back into the blood vessels.
- Conditions
- ECMO Treatment, ARDS, Pneumonia, Intensive Care
- Trial name
- NCT06593717
- Testing
- Transthoracic Echocardiography, Uncalibrated Pulse Contour Analysis, Transpulmonary Thermodilution/Calibrated Pulse Contour Analysis
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Extracorporeal Membrane Oxygenation Complication
Anticoagulation-free VV ECMO for Acute Respiratory Failure
Currently international experts recommend therapeutic anticoagulation for veno-venous extracorporeal membrane oxygenation (VV-ECMO).
- Trial name
- A-FREE ECMO (NCT04273607)
- Testing
- Subcutaneous Heparin
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Damian Ratano