Clinical trials: Vaccination Reaction
Vaccine Reaction
Evaluation of Immunoprotection Provided by Hepatitis B Vaccine After Birth in Healthy Children
Worldwide, hepatitis B virus (HBV) infection is a major cause of acute hepatitis,and chronic infection with HBV often leads to chronic hepatitis, liver cirrhosis,and hepatocellular carcinoma.
- Trial name
- NCT04439435
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Chongqing Medical University
Vaccine Reaction
Safety and Immunogenicity of HPV Vaccine Administered Intradermally and Intramuscularly Via Needle-Free Injection System
The goal of this clinical trial is to evaluate the safety and immunogenicity of an HPV Vaccine (Gardasil) delivered by intramuscular needle-free injection and intradermal needle-free injection.
- Trial name
- NCT06142461
- Testing
- Gardasil, PharmaJet Stratis® Needle-Free Injection System, PharmaJet Tropis® Needle-Free Injection System
- Where
- Indonesia
- Volunteers
- healthy volunteers welcome
- Sponsor
- PharmaJet, Inc.
BCG Infection, Reaction - Vaccine
A Study of the Interaction Between BCG And MenC Immunisation: BAM
The Bacille Calmette-Guérin (BCG) vaccine is the only vaccine licenced to prevent tuberculosis (TB). The stimulus it gives to the immune system allows it to respond more effectively to a subsequent infection with TB.
- Conditions
- BCG Infection, Reaction - Vaccine, Immune Response
- Trial name
- BAM (NCT02002156)
- Testing
- BCG, NeisVac-C®, Pediacel®, Infanrix™, Prevenar-13®, Menitorix®, Priorix®, Rotarix®, NeisVac-C®, Pediacel®, Infanrix™, Prevenar-13®, Menitorix®, Priorix®, Rotarix®
- Where
- United Kingdom
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Japanese Encephalitis, Vaccine Preventable Disease
Seroprevalence of Neutralizing Antibodies Against Japanese Encephalitis Virus Among 6 Years Old Children With 5 Different Immunization Strategies in Zhejiang Province
This study is to evaluate the seroprevalence of neutralizing antibodies against Japanese encephalitis (JE) virus in children aged 6 years who were previously administered with 5 different immunization strategies by JE attenuated…
- Conditions
- Japanese Encephalitis, Vaccine Preventable Disease, Vaccine Reaction
- Trial name
- NCT04817917
- Testing
- Japanese Encephalitis Vaccine (Vero Cell), Inactivated;, No prospective interventions
- Where
- 3 sites in China
- Volunteers
- 712 people, healthy volunteers welcome
- Sponsor
- Zhejiang Provincial Center for Disease Control and Prevention
COVID-19, Vaccine Reaction
Modification of the COVID-19 Vaccine Response by an Intervention on the Intestinal Flora
The elderly, who are often in poorer health, have been particularly affected by the COVID-19 pandemic. Recent study results show that while vaccines have been very effective in the short term, protection for the elderly may not…
- Conditions
- COVID-19, Vaccine Reaction, Elderly
- Trial name
- PIRATES-COV (NCT05195151)
- Where
- Canada
- Volunteers
- 592 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Vaccine Reaction
A Comparison of Safety and Immunogenicity of Rabies Pre Exposure Prophylaxis Regimen Between Gvt of India Approved and WHO Approved.
The goal of this clinical trial is to compare WHO recommended PrEP Vaccination Schedule, 2 doses 0.2ml 2 sites (0.1ml each site) on day 0 and day 7 and Government of India currently recommended PrEP Schedule, 0.1ml 3 doses on day…
- Trial name
- NCT06066294
- Testing
- Regimen 1, Regimen 2
- Where
- India
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Kempegowda Institute of Medical Sciences, Bangalore
Vaccine Reaction
A Trial For The Study of Falciparum Malaria Protein 014 Administered Via Intramuscular Injection in Healthy Adults
A Phase 1, open label clinical study to evaluate the safety, immunogenicity, tolerability and efficacy of Plasmodium falciparum Malaria Protein 014 (FMP014) combined with (ALF with QS-21), saponin molecule derived from the bark…
- Trial name
- NCT04296279
- Testing
- FMP014, ALFQ
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- U.S. Army Medical Research and Development Command
Immune System Diseases, COVID-19 Vaccine Adverse Reaction
COVID-19 Post-Vaccination Observation
The study started after the second COVID-19 vaccination of the participant with blood spots appearing on the skin with severe arthritis.
- Conditions
- Immune System Diseases, COVID-19 Vaccine Adverse Reaction, Immune System Disorder
- Trial name
- NCT06107348
- Where
- China
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Yang I. Pachankis, PhD
Vaccination, Reaction - Vaccine
To Evaluate the Immunogenicity and Safety of Sequential Immunization Schedules of Sabin IPV and bOPV
The purpose of this study is to evaluate the immunogenicity and safety of sequential immunization schedules of Sabin IPV and bOPV.
- Trial name
- NCT04054492
- Testing
- Sabin-IPV+bOPV+bOPV, Sabin-IPV+Sabin-IPV+bOPV, Sabin-IPV+Sabin-IPV+Sabin-IPV
- Where
- China
- Volunteers
- 604 people, healthy volunteers welcome
- Sponsor
- China National Biotec Group Company Limited
Covid19, Vaccine Reaction
Post COVID-19 Vaccination Analysis in Healthcare Worker Recipients
This research study is studying how healthcare worker recipients react after receiving vaccinations for COVID-19. The objective of the study is to evaluate the immune response to COVID-19 vaccination.
- Trial name
- NCT04922944
- Testing
- COVID-19 vaccine
- Where
- United States
- Volunteers
- 167 people
- Sponsor
- Huntington Memorial Hospital
Diabetes Mellitus, BCG Vaccination Reaction
Diabetes Diagnosis, Management, Prevention and Education in Guinea-Bissau
Type 2 diabetes (T2D) will affect ~650 million adults worldwide by 2040 and about as many will have pre-diabetes. Chronic hyperinsulinemia/insulin resistance precedes T2D development.
- Trial name
- BCGTODM (NCT05591339)
- Testing
- BCG vaccine (two doses, 4 weeks apart)
- Where
- Guinea-Bissau
- Volunteers
- 200 people
- Sponsor
- Bandim Health Project
COVID-19 Vaccination, Vaccine Adverse Reaction
Post Vaccination Adverse Events in Covid-19 Vaccine Recipients
Covid-19 pandemic is caused by Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-Cov-2) since its outbreak 2019. Protection against Covid-19 can be achieved through global immunization.
- Trial name
- NCT05254977
- Testing
- Standard Preparation
- Where
- Pakistan
- Volunteers
- 3,515 people, healthy volunteers welcome
- Sponsor
- Islamia University of Bahawalpur
Rheumatoid Arthritis, Autoimmune Diseases
One or Two Week Methotrexate Discontinuation on Efficacy of Influenza Vaccination in Rheumatoid Arthritis.
This is a multi-center, randomized, single-blinded, prospective, parallel group intervention study to investigate whether methotrexate (MTX) discontinuation for 1 week is non-inferior to MTX discontinuation for 2 weeks in regard…
- Conditions
- Rheumatoid Arthritis, Autoimmune Diseases, Influenza, Vaccine Reaction
- Trial name
- NCT05069714
- Testing
- MTX-hold
- Where
- 3 sites in South Korea
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Vaccination Reaction
Longitudinal Evaluation of Antibody Kinetics of Vaccinated Patients With Non-mandatory Vaccine Following Administration of a Non-public Marketed Vaccine in the General Population, Real-life Study
The study would make it possible to document more explicitly the evolution of antibody titers at following a non-public vaccination over a large post-vaccination period in the French population .
- Trial name
- ELCAV (NCT06373510)
- Testing
- Blood collection
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- CerbaXpert
Vaccine Reaction
Immunogenicity and Safety of DTaP or DT Vaccine in 6 Year Old Children ( DTaP/DT )
This study is to evaluate the immunogenicity and safety of DTaP or DT given in children aged 6 years.
- Trial name
- DTaP/DT (NCT05870631)
- Testing
- vaccinate with DTaP, vaccinate with DT
- Where
- 2 sites in China
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Zhejiang Provincial Center for Disease Control and Prevention
Yellow Fever Vaccination Reaction
Study of the Safety and Immunogenicity of Reduced Doses of the US Yellow Fever Vaccine
This is an open-label, randomized, exploratory study to evaluate the human immune response to reduced subcutaneous (SQ) dosing of Yellow Fever vaccine compared to the standard FDA approved subcutaneous vaccination dose.
- Trial name
- NCT05374317
- Testing
- Yellow Fever Vaccine
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- US Army Medical Research Institute of Infectious Diseases
Vaccine Reaction
(VIII): The Eight Study and Immunologic Response Sub-study
The study's objective is to test the hypothesis that immune system activation and subsequent systemic inflammation can be detected through continuously tracking multiple bio signals including physiologic variables (ECG, skin…
- Trial name
- NCT05237024
- Where
- 2 sites in United States, Canada
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- physIQ, Inc.
Rabies Vaccination Reaction
The Role of Fatty Acids in Vaccine Efficacy
This study intends to use a randomized controlled trial design to vaccinate all participants against rabies and perform ARA interventions during vaccination to test the efficacy, safety, and intestinal flora of each group after…
- Trial name
- NCT05987384
- Testing
- Arachidonic acid, Sunflower oil, Rabies Vaccine (Vero Cell) for Human Use
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Tsinghua University
COVID-19, Vaccine Reaction
Improving Vaccination in Older Adults by Inducing Autophagy With Spermidine
Easing the morbidity and economic burden of age-related diseases is one of the major medical challenges. One of the key obstacles to healthy ageing is immune senescence, including the failure of lymphocytes to respond adequately…
- Trial name
- NCT05421546
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Vaccination Reaction
Safety, Tolerability, Immunogenicity and Immunological Mechanisms of TETRALITE, a Novel Seasonal Influenza Vaccine
The effect of LiteVax Adjuvant supplemented to licensed seasonal influenza vaccine on safety and immunogenicity will be investigated in both younger and older healthy participants.
- Trial name
- TETRALITE-Ib (NCT06294262)
- Testing
- TETRALITE
- Where
- Belgium
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- LiteVax BV