Clinical trials: Vaccine Hesitancy
COVID-19, Vaccination Hesitancy
An Online Game to Help Canadian Adults Identify COVID-19 Vaccine Misinformation With One-Month Follow-Up
COVID-19 vaccine misinformation contributed to vaccine hesitancy and preventable illness. This study tested whether a brief online game helps Canadian adults identify COVID-19 vaccine misinformation, and whether effects last one…
- Conditions
- COVID-19, Vaccination Hesitancy, Health Misinformation, Communication
- Trial name
- NCT07758296
- Testing
- Gamified misinformation refutation quiz, Refutational text blog post (active control)
- Where
- United States
- Volunteers
- 4,071 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Behavior, Intention
Incentives & Motivation for Behavior Change:
In a series of controlled, randomized experiments, we will systematically manipulate exposure to health-related messages and/or survey methods to examine the effects on behavioral intention.
- Trial name
- NCT04747327
- Testing
- mandate public, employer mandate, incentive reward
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
COVID-19, Vaccine Refusal
CATCH-UP Vaccines: Engaged Approaches to Testing in Community/Healthcare Settings for the Underserved (COVID-19)
Oklahoma has high COVID-19 incidence, particularly among underserved minority and rural Oklahomans. Oklahoman's are also reporting SARS-CoV-2 vaccine hesitancy and signs of slowing vaccine uptake, with increased hesitancy among…
- Trial name
- NCT05236270
- Testing
- Text Message, Motivational Interviewing, Electronic Educational Message with Tailored Questions/Prompts
- Where
- United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
COVID-19
Puerto Rico COVID-19 Vaccine Uptake Study
The purpose of this study is to recruit a total of 386 participants to evaluate the effectiveness of an educational program to increase the proportion of men and women aged 21 years and older who have received the COVID-19…
- Trial name
- PR-COVACUPS (NCT05468021)
- Testing
- Educational intervention
- Where
- 2 sites in Puerto Rico
- Volunteers
- 394 people, healthy volunteers welcome
- Sponsor
- University of Puerto Rico
HPV, Vaccine Acceptance
Addressing HPV Vaccine Hesitancy by Co-Designing a Digital Health Intervention
This study looks at a digital platform that supports HPV vaccination in schools. The goal is to see if it is useful, easy to use, and practical in real school settings, especially in areas where fewer people get vaccinated.
- Conditions
- HPV, Vaccine Acceptance, Vaccine Decision Making, HPV Vaccination
- Trial name
- HPV-END-IT (NCT07632963)
- Testing
- HPV-Kompassen
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Vaccination Refusal
An Adaptive Prenatal Intervention to Increase Childhood Vaccinations
This study will test whether proactively connecting expectant parents with factual vaccination information during pregnancy can build confidence in vaccinations and lead to timely vaccinations during pregnancy and once their…
- Trial name
- ADEPT (NCT05795855)
- Testing
- ADEPT
- Where
- United States
- Volunteers
- 770 people, healthy volunteers welcome
- Sponsor
- Emory University
Vaccination, Hygiene
Microbe-Literacy Germ-Watching Workshops for Hygiene and Vaccine Acceptance in Sargodha, Pakistan
This cluster randomized controlled trial evaluated whether a single microscope-based "germ-watching" workshop, delivered by Lady Health Workers (LHWs) to mothers and female caregivers of children under three years, improves…
- Conditions
- Vaccination, Hygiene, Vaccine Hesitancy, Health Knowledge Attitudes and Practice
- Trial name
- MLI-Sargodha (NCT07771738)
- Testing
- Microbe-literacy germ-watching workshop
- Where
- Pakistan
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Development Synergies International (Private) Limited
Vaccination Hesitancy
Mobile Health-based Motivational Interviewing to Promote COVID-19 Vaccination
The objective of this study is to evaluate the preliminary efficacy and acceptability of an mobile Health-based motivational interviewing (MI) intervention to promote SARS-CoV-2 vaccination (MOTIVACC) compared to traditional…
- Trial name
- COVID-19 (NCT05977192)
- Testing
- Standard MI, Intensive MI, MOTIVACC
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University
Pneumonia, Influenza
ACTIVATE in Public Housing
This multilevel, multidisciplinary, theoretically based, culturally sensitive, community-engaged intervention sets out to mitigate uptake barriers and non-adherence to vaccination schedules as recommended by the CDC and increase…
- Conditions
- Pneumonia, Influenza, Varicella Zoster, Meningitis
- Trial name
- NCT06075732
- Testing
- Increasing Willingness and Uptake of Influenza, Pneumonia, Meningitis, HZV, and COVID-19 Vaccination
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Charles Drew University of Medicine and Science
Vaccine Hesitancy, Structural Barriers
Advancing Vaccine Equity Through Understanding Vaccine Hesitancy, Barriers, and Trust
In the proposed study, the investigators will conduct qualitative interviews and focus groups with Black, Hispanic, and medically underserved communities, living in the rural south and will provide a quantitative survey (mixed…
- Conditions
- Vaccine Hesitancy, Structural Barriers, Vaccine Trust
- Trial name
- NCT05537714
- Testing
- Qualitative interviews/focus groups
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Vaccine Hesitancy
Culturally and Linguistically Appropriate Vaccine Education
The goal of this clinical trial is to test the effectiveness of culturally tailored social media campaigns and WhatsApp-based vaccine training for healthcare workers in increasing childhood routine and HPV vaccine confidence and…
- Trial name
- CLAVE (NCT06186206)
- Testing
- Social media interventions for vaccine uptake
- Where
- Guatemala
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Vaccination Hesitancy
A Conversational AI System to Enhance Knowledge About Vaccines and Promote Vaccination
This study is designed to contribute to the growing body of evidence on the efficacy of digital health interventions. By rigorously evaluating the impact of the AI system on vaccine knowledge and acceptance, the study aims to…
- Trial name
- NCT05689073
- Testing
- Conversational AI system, Printed educational Brochure
- Where
- China
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Vaccine Hesitancy, Communication
Emphasizing the Personal Versus the Social in Educational Interventions For Decreasing Vaccine Hesitancy
This experimental study aims to investigate the effect of different types of educational interventions on overcoming Coronavirus disease 2019 (COVID-19) vaccine hesitancy among the Higher School of Economics (HSE) bachelor…
- Trial name
- NCT05120817
- Testing
- "Personal" intervention, "Social" intervention, "Personal" + "Social" intervention
- Where
- Russia
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- National Research University Higher School of Economics
COVID-19, Vaccine Hesitancy
COVID-19 Vaccine Hesitancy Among Nurses
The purpose of this study is to investigate the correlation of intention to receive COVID-19 vaccine, recommendation behavior, and 5C psychological antecedents among Nurses.
- Conditions
- COVID-19, Vaccine Hesitancy, Vaccination, Nurses
- Trial name
- NCT05212974
- Testing
- Questionnaires
- Where
- Taiwan
- Volunteers
- 4,258 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
COVID-19, Vaccine Hesitancy
Addressing COVID-19 Vaccine Hesitancy With Muliti-Level Interventions in Appalachia
The purpose of this community-engaged study is to test the ability of county-level strategies to increase uptake of COVID-19 vaccination.
- Trial name
- K-VAC (NCT06505993)
- Testing
- Health Communication, Health Communication + Structural
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Marc Kiviniemi
Covid19, Vaccine Refusal
COVID-19 Vaccine Education at the Point of Testing to Increase Vaccine Uptake in Vulnerable Communities in SE Louisiana
This project is a 2-year study to investigate vaccine hesitancy and vaccine completion among vulnerable communities in the Southeastern Louisiana region.
- Conditions
- Covid19, Vaccine Refusal, Vaccine Hesitancy
- Trial name
- NCT04939506
- Testing
- COVID-19 Vaccine Education at the Point of COVID-19 Testing
- Where
- United States
- Volunteers
- 377 people, healthy volunteers welcome
- Sponsor
- Xavier University of Louisiana.
Social Medium, Data Collection
Social Media-based Vaccine Confidence and Hesitancy Monitoring
History and scientific evidence show that it is critical to maintain public trust and confidence in vaccination. Any crisis in confidence has the potential to cause significant disruption and a detrimental impact on vaccination.
- Conditions
- Social Medium, Data Collection, Patient Acceptance of Health Care, Immunization Programs
- Trial name
- NCT05442762
- Volunteers
- healthy volunteers welcome
- Sponsor
- Fudan University
Influenza, Human, Vaccine Hesitancy
Conversational AI for Adult Flu Vaccination Decisions
This randomized trial tests whether an online guide combining short evidence cards with an AI-guided conversation increases flu-vaccination intention among US adults who haven't decided whether to get a flu vaccine this season.
- Trial name
- NCT07896850
- Testing
- Flu vaccination guide, Accident safety guide
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Calypta Systems, Inc.
Vaccine Hesitancy
Motivational Interviewing and Vaccine Hesitancy in Children
This study will assess the effectiveness of a motivational interviewing-based tool in addressing vaccine hesitancy expressed by parents or caregivers of children.
- Trial name
- MOTIVE (NCT03934008)
- Testing
- MOtivational interviewing Tool to Improve Vaccine AdherencE (MOTIVE)
- Where
- United States
- Volunteers
- 4,191 people, healthy volunteers welcome
- Sponsor
- Cedarville University
Vaccination Uptake
VISTA: Vaccinator-Initiated Screening and TAilored Counseling for Reducing Vaccine Hesitancy
The purpose of this study is to understand why parents do or do not vaccinate their children and explore what information parents need to vaccinate their children.
- Trial name
- NCT04421586
- Testing
- VISTA
- Where
- Tanzania
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Duke University