Clinical trials: Vaginal Birth After Cesarean
Chorioamnionitis
Treatment of Chorioamnionitis After Delivery
Chorioamnionitis occurs in 1% to 5% of term pregnancies and may complicate up to 25% of cases of preterm labor. The traditional regimen used to treat intra-amniotic infection is intravenous ampicillin 2g every 6 hours and…
- Trial name
- NCT00814905
- Testing
- saline, ampicillin gentamicin, Ampicillin gentamicin clindamycin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, Portsmouth
Trial of Labor After Cesarean, Vaginal Birth After Cesarean
Balloon Catheter Combined With Oxytocin Induction Among the Pregnant Women With Previous Cesarean Section
This study is a multi-center, prospective, observational clinical trial study. 924 full-term pregnant women will be enrolled as subjects, and the ratio of eligible subjects in the two groups is 1:1.
- Conditions
- Trial of Labor After Cesarean, Vaginal Birth After Cesarean, Bishop Score, Failed Mechanical Induction
- Trial name
- NCT05246761
- Testing
- Balloon catheter
- Where
- China
- Volunteers
- 924 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Labor Pain, Complications; Cesarean Section
Outcomes of Neuraxial Anesthetic Technique on the Trial of Labor After Cesarean (TOLAC)
To compare the effects of epidural versus combined spinal and epidural (CSE) anesthesia on the success of Trial of Labor After Cesarean (TOLAC).
- Conditions
- Labor Pain, Complications; Cesarean Section, Pregnancy
- Trial name
- NCT02105558
- Testing
- Epidural anesthesia, Combined spinal and epidural anesthesia
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Infection, Obstetric Labor Complications
Vaginal Preparation and Azithromycin to Reduce Post Cesarean Infections
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- Conditions
- Infection, Obstetric Labor Complications, Endometritis, Cesarean Delivery Affecting Fetus
- Trial name
- NCT04163679
- Testing
- Vaginal Preparation
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Womack Army Medical Center
Previous Cesarean Section Scar
Clinical and Ultrasound Score for Evaluation of Previous Cesarean Section Scar
Cesarean delivery rates have increased dramatically worldwide. In the United States, cesarean section (CS) rates increased from 5% of all deliveries in 1970 to a high of 31.9% in 2016.Although efforts were made to reduce the…
- Trial name
- NCT04856254
- Testing
- Trial of labor after cesarean section
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Endometrial, Infection
EFFECTIVENESS OF PREOPERATIVE VAGINAL CLEANING IN REDUCING POST CAESAREAN INFECTIOUS MORBIDITY
After obtaining an informed consent a detailed history and clinical examination was performed. Labs were carried out to fulfill inclusion and exclusion criteria. Women were randomly divided into two groups.
- Conditions
- Endometrial, Infection, Surgical Site Infection Following Cesarean Delivery
- Trial name
- NCT07053995
- Testing
- Vaginal cleaning, Non vaginal cleansing
- Where
- Pakistan
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Khyber Teaching Hospital
Cesarean
Impact of Doula Support on Childbirth Outcomes for Women Undergoing a Vaginal Birth After Cesarean (VBAC)
The purpose of this study is to evaluate the impact of doula support on childbirth outcomes of women who are eligible for and attempting to have a Vaginal Birth After Cesarean (VBAC).
- Trial name
- NCT01216098
- Testing
- Doula support
- Where
- Canada
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Pain
Is Paracetamol an Effective Treatment for Chronic Moderate Pain in the Newborn After Operative Vaginal Delivery?
There are many reasons for using a vacuum apparatus or forceps to assist in delivering a baby. The traction and pressure on the baby's head due to the vacuum apparatus or forceps may cause pain and discomfort for some time after…
- Trial name
- NCT00488540
- Testing
- Paracetamol
- Where
- 3 sites in Switzerland
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Postpartum Hemorrhage
Rotational Thromboelastometry for the Transfusion Management of Postpartum Hemorrhage After Vaginal or Cesarean Delivery
The aim of this study is to evaluate the impact of a rotational thromboelastometry (ROTEM®)-based transfusion protocol during postpartum hemorrhage (PPH) after vaginal or cesarean delivery.
- Trial name
- NCT03064152
- Testing
- Rotational Thromboelastometry
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Instrumental Delivery, NEC, Affecting Fetus or Newborn
PROPENSITY-ID: Sonographic and Clinical Assessment of Head Position Prior to Instrumental Delivery and Labour Outcomes
Instrumental delivery is performed in 3-15% of all births (1). Successful instrumental delivery avoids need for cesarean section with associated maternal surgical morbidity, risk from neonatal disimpaction and future pregnancy…
- Conditions
- Instrumental Delivery, NEC, Affecting Fetus or Newborn, Second Stage Cesarean Delivery, Occiput Position
- Trial name
- PROPENSITYID (NCT05557097)
- Testing
- Intrapartum sonography
- Where
- Italy
- Volunteers
- 2,282 people, healthy volunteers welcome
- Sponsor
- University of Parma
Pelvic Floor Disorders
Pelvic Floor Function After Vaginal and Cesarean Delivery Among Egyptian Women
A cross sectional study for assessment of pelvic floor functions after 6 months to 4 years after normal vaginal delivery or Cesarean section
- Trial name
- NCT03126604
- Testing
- female sexual function index
- Where
- Egypt
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Cairo University
Contraception
Verbal Analgesia During Copper IUD Insertion After Cesarean Delivery
This open-label, parallel-group randomized controlled trial evaluated whether structured verbal analgesia reduces pain during Copper T380A intrauterine device insertion compared with standardized neutral communication in women…
- Trial name
- NCT07326007
- Testing
- Verbal Analgesia, Providers will use a standardized neutral script with brief instructions only (e.g., "I am now placing the speculum," "I am sounding the uterus," "The IUD is being inserted," "The procedure is complet
- Where
- Egypt
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Cairo University
Site Infection, Cesarean Section; Complications, Wound, Infection (Following Delivery)
Vaginal Microbiota and Post-cesarean SSI
The goal of this observational study is to investigate the relationship between vaginal microbiota composition and the development of post-cesarean section wound infection in women undergoing cesarean delivery.
- Trial name
- NCT06840041
- Testing
- Vaginal swab and culture
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Scar; Previous Cesarean Section, Vaginal Birth After Cesarean
University of North Carolina-Healthwise Partnership Project on Birth Options Decision Aid
This is pilot quasi-experimental study of women with one or two prior cesarean deliveries who are now pregnant and eligible for a trial of labor after cesarean delivery, to assess whether a decision aid, providing knowledge about…
- Conditions
- Scar; Previous Cesarean Section, Vaginal Birth After Cesarean, Decision Making, Shared
- Trial name
- B-READY (NCT04053413)
- Testing
- Decision Aid
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Trial of Labor After Cesarean, Vaginal Birth After Cesarean
The Effectiveness and Safety of the Trial of Labor in Full Term Pregnant Women With Cesarean Section After Spontaneous Labor
This study is a multi-center, prospective, observational clinical trial study. 510 full-term pregnant women will be enrolled as subjects, and the ratio of eligible subjects in the two groups is 1:1.
- Conditions
- Trial of Labor After Cesarean, Vaginal Birth After Cesarean, Spontaneous Labor
- Trial name
- NCT05215041
- Testing
- Non intervention
- Where
- China
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Labour, Induced, Vaginal Birth After Caesarean
Membrane Sweeping Versus Transcervical Foley Catheter for Induction of Labour in Women With Previous Caesarean Delivery
Nowadays, more and more women embark on pregnancy with previous Caesarean scar. One in five pregnancies requires induction of labour.
- Trial name
- NCT03326557
- Testing
- Membrane Sweeping versus Transcervical Foley Catheter for Induction of Labour in Women with Previous Caesarean Delivery
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Malaysia
Vaginal Birth After Cesarean Section
Role of Membrane Sweeping on Initiation of Labor and Vaginal Birth in Previous Cesarean Section
In Pakistan rate of child birth through cesarean section increased from 3.2% in 1992 to 22% in 2018 .Due to increasing rates of cesarean sections and associated morbidity the investigators should focus to reduce rate of primary…
- Trial name
- NCT06103071
- Testing
- Sweeping of membranes
- Where
- Pakistan
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- HITEC-Institute of Medical Sciences
Duration of Labor
Obstetrical Gel and Its Impact in Shortening the Duration of Labor in Women Undergoing a Vaginal Birth After Cesarean (VBAC)
The objective of our study is to investigate whether the use of obstetric gel shortens the first and second stage of labor and exerts a protective effect on the lower genital tract in women undergoing a Vaginal Birth After…
- Trial name
- NCT03751553
- Testing
- obsteric gel(k-Y jelly)
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cesarean and Vaginal Birth Complications
Assessment of Lumbar Spine Active Range of Motion in Women Who Were Experienced Cesarean or Vaginal Birth
Pregnancy may impact the musculoskeletal apparatus of females through pregnancy-associated biomechanical, vascular, and hormonal changes. Pregnant females may complain of lumbopelvic pain, especially during their last trimester.
- Trial name
- NCT05538325
- Testing
- Bubble Inclinometer and Digital Pelvic Inclinometer
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- South Valley University
Pregnancy
Measuring Preferences for Childbirth After Cesarean
The objective of this proposed 18-month exploratory research study is to help pregnant women weigh risks and benefits in a childbirth decision using the Preferences-Assessment Computer Module.
- Trial name
- NCT00267735
- Testing
- Use of Computerized Decision Aid on Childbirth
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University