Clinical trials: Vaginal Candidiasis
Candidiasis, Vulvovaginal
Use of 405nm Blue Light Emitting Diode in the Treatment of Women With Vulvovaginal Candidiasis: a Clinical Trial
Vulvovaginal candidiasis (CVV) is an infectious process of the female genitourinary tract, an important health issue due to the high incidence and difficulties encountered in the treatment.
- Trial name
- NCT03075046
- Testing
- Blue LED 405 nm, Questionnaire of anamnesis
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Centro de Atenção ao Assoalho Pélvico
Vaginal Diseases
Probiotic for Vaginal Candidiasis in Pregnant Women
This project aims to study the benefits of a probiotic product, STP4 for vaginal health properties, primarily prevention of vaginal candidiasis, among pregnant women in second and third trimester pregnancy.
- Trial name
- NCT03940612
- Testing
- STP4 (product with probiotics)
- Where
- Malaysia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Vaginal Infection
Evaluation of Intravaginal Gel and Ovule Formulations of TOL-463
The purpose of this study is to determine the safety, local tolerability and pharmacokinetic parameters of TOL-463 intravaginal dosage forms in both healthy, nonpregnant females following single dose administration (Part 1), and…
- Trial name
- NCT01812889
- Testing
- TOL-463 Vaginal ovule, TOL-463 Vaginal gel
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Bacterial Vaginosis, Candida Vaginitis
Performance Study of the Cobas® BV/CV Test on Samples From Participants With and Without Symptoms of Bacterial Vaginosis and Candida Vaginitis
In the clinical performance part of this study, prospectively acquired clinician-collected and clinician-instructed, self-collected vaginal swab specimens collected in cobas® PCR Media will be taken from a minimum of 500…
- Trial name
- NCT06975436
- Testing
- cobas® BV/CV test, BD Max™ Vaginal Panel, Cepheid Xpert Xpress MVP
- Where
- 10 sites in United States, Bulgaria and 1 more
- Volunteers
- 738 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Bacterial Vaginosis, Vulvovaginal Candidiasis
TOL-463 Phase 2 Study for Vaginitis
This is a Phase II study designed to assess the safety and efficacy of an investigational product, TOL-463, to treat vaginitis.
- Trial name
- NCT02866227
- Testing
- TOL-463
- Where
- 2 sites in United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Toltec Pharmaceuticals, LLC
Microbiome, Antibiotic-Induced VVC
Study of Antibiotic-induced Vaginal Yeast Infections in Healthy Women
Background: Vaginal yeast infections are caused by a fungus called Candida. Candida can live harmlessly in the vagina, but most women will have symptoms from a vaginal yeast infection at some point during their life.
- Conditions
- Microbiome, Antibiotic-Induced VVC, Vaginal Candidiasis
- Trial name
- NCT01915251
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Vaginal Infection, Candidiasis
Investigation of the Relationship Between Salivary Histatine-5 Level and Vaginal Candidiasis in Women
The low Histatine-5 (HST-5) level of the saliva can lead to vaginal candidiasis. Because HST-5 level in the saliva can effect vaginal Ph, flora and local defence mechanisms.
- Trial name
- NCT05044156
- Testing
- salivary sample
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Usak State Hospital
Candidosis Vaginal
Safety and Tolerability Studies of CanProFem-AK, Vaginal Suppositories in Healthy Volunteers
The study object of this clinical trial is CanProFem-AK, 100 mg suppositories. The Pharmacological group - Antifungal drug for external use.
- Trial name
- NCT06535126
- Testing
- CanProFem-AK
- Where
- Kazakhstan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Industrial Microbiology LLP
Bacterial Vaginosis, Vulvovaginal Candidiasis
Comparing NAAT Testing to Standard Methods for the Diagnosis of Vaginitis
Vaginitis is the most common condition encountered in the gynecologist's office and is most commonly caused by bacerial vaginosis (BV), vulvovaginal candidiasis (VVC) and Trichomonas vaginalis (TV).
- Conditions
- Bacterial Vaginosis, Vulvovaginal Candidiasis, Trichomoniasis
- Trial name
- VAST (NCT02203942)
- Testing
- NAAT testing
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Bacterial Vaginosis, Candidiasis
Vaginal Ecosystem and Network in the United States Study
The central premise of this study is that the intricate balance and diversity of the vaginal microbiome plays a pivotal role in the onset, progression, and severity of various gynecological conditions.
- Conditions
- Bacterial Vaginosis, Candidiasis, Urinary Tract Infections, Genitourinary Syndrome of Menopause
- Trial name
- VENUS (NCT06472765)
- Testing
- Vaginal Swab Collection
- Where
- 21 sites in United States, Canada
- Volunteers
- 3,250 people, healthy volunteers welcome
- Sponsor
- Vaginal Biome Science
Sexually Transmitted Disease, Bacterial Vaginosis
Women's Improvement of Sexual Health (WISH) Demonstration Project
The current standard of care for urogenital infections in Rwanda is syndromic management. Many urogenital infections are asymptomatic and therefore completely missed, and the management of vaginal discharge syndrome is known to…
- Conditions
- Sexually Transmitted Disease, Bacterial Vaginosis, Vaginal Candidiasis, Urinary Tract Infections
- Trial name
- WISH (NCT03045809)
- Testing
- Urogenital infection point-of-care tests
- Where
- Rwanda
- Volunteers
- 705 people, healthy volunteers welcome
- Sponsor
- Janneke van de Wijgert
Vaginitis
Management of Vaginal Complaints: A Pilot Study Within a Practice-Based Research Network
Many women present in primary care with vaginal complaints. The best way of managing these complaints is unclear. This trial will test two different methods of managing patients with vaginal complaints. This is a pilot trial.
- Trial name
- VCAT (NCT00503542)
- Testing
- Terazol or oral fluconazole for candidal vaginitis, Metronidazole or Clindamycin for Bacterial Vaginosis, Flagyl for definitively diagnosed vaginal trichomoniasis
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)
Vulvovaginal Candidiasis
Patients With Vulvovaginal Candidiasis
The present study aims to evaluate the safety of two mucoadhesive gels containing a propolis standardized extract identified as EPP-AF, with 1 and 2% of propolis.
- Trial name
- EPP-AFG-VVC (NCT03024502)
- Testing
- EPP-AF Gel 1%, EPP-AF Gel 2%, Clotrimazole
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Candidiasis, Vulvovaginal
Epidemiological Study About the Evolution of Patients Treated for an Acute Episode of Vulvovaginal Candidiasis
To determine proportion of women achieving clinical and mycological cure or have recurrences / reinfection after being treated for an acute episode of vulvovaginal candidiasis.
- Trial name
- NCT02248506
- Testing
- Clotrimazole
- Where
- Spain
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Instituto Palacios
Vulvovaginal Candidiasis
Multi-Gyn FloraFem Study for Treatment of Vulvo Vaginal Candidiasis Symptoms
Women diagnosed with Vulvovaginal Candidiasis by the health care professional will be enrolled in the study. All participants should fulfil inclusion and exclusion criteria. The study product will be used for 5 days, once a day.
- Trial name
- NCT05552378
- Testing
- Multi-Gyn FloraFem
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Karo Pharma AB
Vaginal Infection, ASC-US
Probiotic Implementation as Help in Solving Vaginal Infections
Over recent years, a growing interest has developed in microbiota and in the concept of maintaining a special balance between Lactobacillus and other bacteria species in order to promote women's well-being.
- Trial name
- NCT03372395
- Testing
- Lactobacillus rhamnosus BMX 54
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Vaginitis
A Study of the Efficacy and Safety of WXSH0102 in Treating VCC Patients
This study is a multicenter, randomized, double-blind, active-controlled, dose-ranging clinical trial designed to evaluate the efficacy and safety of the investigational drug compared to the active comparator in the treatment of…
- Trial name
- NCT06771063
- Where
- 2 sites in China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Cisen Pharmaceutical CO., LTD.
Vulvovaginal Candidiasis
Comparative Performance of a Vaginal Yeast Test
The purpose of this study is to establish lay user performance criteria for the SavvyCheck Vaginal Yeast Test in comparison to standard vaginal yeast culture and identification method for Candida (the Reference Method).
- Trial name
- NCT05079711
- Testing
- SavvyCheck Vaginal Yeast Test (rapid, point-of-care diagnostic test)
- Where
- 3 sites in United States, Germany
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Uniformed Services University of the Health Sciences