Clinical trials: Vaginal Flora
Vaginosis, Bacterial
Identification and Impact of Vaginal Flora Anomalies Among Pregnant Woman
This is a prospective multicentric study including six clinical units of Gynecology and Obstetrics (5 public health hospital and one private team), one research team in clinical microbiology and one Center of Clinical…
- Trial name
- NCT00484653
- Testing
- cervical smear
- Where
- 6 sites in France
- Volunteers
- 1,000 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Premature Birth, Bacterial Vaginosis
Effect of Probiotic Lactobacilli on Vaginal Flora of Pregnant Women at High Risk for Preterm Delivery
Purpose of the study is to determine the effect of probiotic lactobacilli on the vaginal flora and cytokine profile during pregnancy, and the incidence of preterm labour in women at high risk for preterm birth.
- Trial name
- NCT00217308
- Testing
- Lactobacilli GR-1 and RC-14
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Human Papilloma Virus, Vaginal Flora Imbalance
Vaginal Microbiome and HPV Pre-malignant and Cervical Dysplasia
In this study, the investigators will prospectively collect, analyze and integrate information regarding vaginal microbiome composition and HPV presence in women with cervical pathologies (high-grade CIN and CC) and controls, to…
- Conditions
- Human Papilloma Virus, Vaginal Flora Imbalance, Cancer Cervix Uterus, Cervical Dysplasia
- Trial name
- NCT05640700
- Where
- Israel
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Pre- Peri, and Postmenopausal Women
Tocopherol Acetate Vaginal Administration in Pre-peri and Postmenopausal Women
The purpose of this non-controlled Investigator Initiated Trail (IIT), with a retrospective design is to evaluate the performance and safety of the vaginal administration of tocopherol acetate (vitamin E) in pre-peri and…
- Trial name
- NCT05918848
- Testing
- Filme Gyno-V® Vaginal Ovules
- Volunteers
- 50 people
- Sponsor
- Gemelli Molise Hospital
Vaginal Flora Imbalance
Stryphnodendron Adstringens Intimate Soap
This is a single-centre, single-blind, non-comparative clinical trial to assess the safety of the investigational product through clinical probability assessment.
- Trial name
- NCT06085898
- Testing
- Stryphnodendron Adstringens 3% - once daily post bath
- Where
- Brazil
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Biolab Sanus Farmaceutica
Bacterial Vaginosis, Vaginal Flora Imbalance
Clinical Trial to Survey Results of Flourish Vaginal Care System for Recurrent Bacterial Vaginosis
Background Bacterial Vaginosis is the most common vaginal infection in women in their reproductive years and a difficult one to treat.
- Trial name
- NCT03734523
- Testing
- Flourish Vaginal Care System
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Vaginal Biome Science
Vaginosis, Bacterial, Vaginal Flora Imbalance
Vaginal Ovule With Flavonoid Tea Extract for the Correction of Imbalance in the Vaginal Environment
Randomized, blinded vehicle-controlled multicenter clinical trial (MAT072017) to determine the effect of vaginal ovules containing 2 mg of the tea extract Matuzalem on the subjective symptoms (5-point scale pruritus (itching)…
- Trial name
- MAT072017 (NCT04171947)
- Testing
- Matuzalem ovule, Vehicle ovule
- Where
- 14 sites in Czechia
- Volunteers
- 274 people
- Sponsor
- Value Outcomes Ltd.
Vaginal Flora Imbalance
FB101 Intervention in Women Screened to Have Vaginal Dysbiosis
This study will explore and map the potential shifts in vaginal microbiomes as a consequence of a microbial intervention with product FB101 in healthy, asymptomatic volunteer women screened to have vaginal dysbiosis based on…
- Trial name
- DYSCOVER-1 (NCT05114031)
- Testing
- FB101
- Where
- Ireland
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Freya Biosciences ApS
Vaginal Flora Imbalance
Vaginal Profile in IVF/ICSI and Impact on Clincal Outcome
Vaginal flora is closely related to female reproductive health. Previous studies have suggested that the composition of the vaginal flora is related to the pregnancy outcomes, and abnormalities in the vaginal flora lead to a…
- Trial name
- NCT04202302
- Testing
- IVF/ICSI
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Infertility, Vaginal Flora Imbalance
Evaluate the Use of a New Probiotic Strain in Couples With Fertility Problems and Dysbiosis.
Pilot study to evaluate the effect of the strain Lactobacillus PS11610 on the microbiota of the female and male genital tract in couples with fertility problems.
- Conditions
- Infertility, Vaginal Flora Imbalance, Genital Disorder
- Trial name
- PROFEC (NCT03701893)
- Testing
- Lactobacillus PS11610
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- ProbiSearch SL
Vaginal Flora Imbalance
FB101 Intervention in Women Screened to Have Vaginal Dysbiosis (Dyscover-3)
This study will explore and map the potential shifts in vaginal microbiomes as a consequence of a microbial intervention with product FB101 in healthy, asymptomatic volunteer women screened to have vaginal dysbiosis based on…
- Trial name
- Dyscover-3 (NCT05850078)
- Testing
- FB101
- Where
- Ireland
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Freya Biosciences ApS
Infertility, Overweight and Obesity
Healthy Parents - Healthy Children. Weight Loss Before Fertility Treatment
The detrimental effect of overweight and obesity on fecundity has been well documented. The investigators wish to investigate the intervention program for weight loss before fertility treatment.
- Conditions
- Infertility, Overweight and Obesity, Weight Loss, Vaginal Flora Imbalance
- Trial name
- NCT04721938
- Testing
- Systematic weight loss intervention
- Where
- Denmark
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Preterm Birth
Study of the Risk of PREMaturité According to the Balance of Bacterial Flora VAginale
Objective To compare vaginal microbiota in the first trimester of pregnancy between spontaneous preterm and term deliveries
- Trial name
- PREMEVA2 (NCT03618836)
- Testing
- Microbiological and biological patterns on vaginal samples
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Lille
Vaginitis Bacterial, Inflammation, Ear
Effect of Lactobacillus Johnsonii or White Pomegranate Extract on the Vaginal Health
The goal of this clinical trial is to explore the effect of Lactobacillus johnsonii and white pomegranate extract on female bacterial status, it aims to answer are: Evaluate Lactobacillus johnsonii TCI250 probiotics or white…
- Trial name
- NCT06069531
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Chung Shan Medical University
Vaginal Flora Imbalance
Vaginal Microbiome and IVF Pregnancy Outcome
The aim of this prospective, observational study is to investigate the prevalence of vaginal dysbiosis among women undergoing IVF procedures in the US.
- Trial name
- NCT05150639
- Testing
- IVF
- Where
- United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Freya Biosciences ApS
Bacterial Vaginosis (BV), Recurrent Bacterial Vaginosis
Evaluation of the Medical Device Vagitab - T as Adjuvant Therapy in Patients With Bacterial Vaginosis.
This clinical trial is looking at how well and safely the vaginal administration of Vagitab-T works . Vagitab-T is already on the market in several countries in Europe as a medical device.
- Trial name
- Vagitab (NCT06725888)
- Testing
- Vagitab -T vaginal tablets. Components: tyndallized probiotic L. plantarum HA-119, lactic acid, and xylo-oligosaccharides, lauryl glucoside, and macrogol 3350:
- Where
- Romania
- Volunteers
- 30 people
- Sponsor
- S.I.I.T. Srl
Recurrent Vulvovaginal Candidiasis
Study of Lactobacillus in Adjuvant Treatment of RVVC
We are trying to determine if Clotrimazole vaginal tablets with oral Lactobacillus is better than Clotrimazole vaginal tablets in Preventing the Recurrence of vulvovaginalcandidiasis
- Trial name
- NCT04699240
- Testing
- clotrimazole vaginal tablets, Clotrimazole vaginal tablets+ Lactobacillus
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Peking University Shenzhen Hospital
Urinary Tract Infections, Vaginal Flora Imbalance
Vaginal Care System for Menopausal Women With Urinary Tract Infections
Menopausal women have an increased risk of recurrent urinary tract infections. This is likely due in part to hormonal changes occurring during menopause.
- Trial name
- NCT05573334
- Testing
- BioNourish
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Vaginal Biome Science
Bacterial Vaginosis (BV)
Multistrain Probiotics Against Bacterial Vaginosis
The primary aim of the study is to clarify whether and to what extent the consumption of the multistrain probiotic OMNi-BiOTiC® FLORA plus+ has a positive effect on the vaginal flora and reduces BV.
- Trial name
- NCT06888518
- Testing
- OMNi-BiOTiC® FLORA plus+, antibiotic
- Where
- Austria
- Volunteers
- 56 people
- Sponsor
- Institut AllergoSan Pharma GmbH
Vaginal Flora Imbalance
Chlorhexidine Gluconate Versus Povidone-iodine
A hysterectomy, or removal of the uterus, is a common surgery performed for a variety of reasons. During this surgery, to prevent infection, the vagina is thoroughly prepped with a cleansing solution, most commonly chlorhexidine…
- Trial name
- CHDvPI (NCT04658355)
- Testing
- Chlorhexidine Gluconate, Povidone-iodine
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Arizona