Clinical trials: Vaginal Health
Vaginal Personal Care
Randomized, Double-blind, Placebo-controlled Trial Investigating the Role of a Personal Care Product on Vaginal Health
The goal of this clinical trial is to assess the impact of a personal care product on vaginal health in a healthy participant population.
- Trial name
- NCT05659745
- Testing
- VM-02, Commercial Oral Probiotic Competitor
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Seed Health
Postoperative Bleeding, Patient Satisfaction
Reducing Postoperative Bleeding After Hysterectomy Via Independent Closure of Vaginal Cuff Angles
The investigators propose prospectively evaluating if adding separate sutures to the angles of the vaginal cuff before running barbed suture reduces the incidence of patient's perception of bleeding after surgery.
- Conditions
- Postoperative Bleeding, Patient Satisfaction, Complications, Operative Time
- Trial name
- NCT05174988
- Testing
- Angle stitch
- Where
- United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Pregnancy
The Effect of Probiotics on Maintenance of Health in Pregnancy and Infants
This phase 2 study evaluates the effect of perinatal use of probiotics on the number of diagnosed viral, bacterial and fungal infections in pregnant women and on the maintenance of a health pregnancy.
- Trial name
- NCT03310853
- Testing
- Probiotic
- Where
- Canada
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Lallemand Health Solutions
Uterine Cervical Neoplasms
Improving Access to Cervical Cancer Screening
Every year, in France, 3 000 women are diagnosed with cervical cancer, and 1 000 die each year. Recent studies highlighted regional, social and economical inequalities with respect to cervical cancer incidence.
- Trial name
- NCT03118258
- Testing
- 'Pap smear' arm, 'Self-collected vaginal swab for HPV testing + pap smear triage' arm
- Where
- France
- Volunteers
- 1,258 people, healthy volunteers welcome
- Sponsor
- Médecins du Monde
Vaginal Dysbiosis, Vaginal Disease
Feasibility of an Oral Intervention for Sexual Health in Transgender Men
Transgender men (TGM) have a high incidence of sexually transmitted infected (STIs), including HIV, HPV and bacterial N. gonorrhea and C. trachomatis.
- Conditions
- Vaginal Dysbiosis, Vaginal Disease, Molecular-bacterial Vaginosis
- Trial name
- TEST-F (NCT06470906)
- Testing
- Probiotic Group
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Columbia University
Anxiety
An Informative Video About Perineal Tears During Labor for Anxiety Reduction: A Randomized Controlled Trial
This study evaluates the impact of an informative video about perineal tears on maternal anxiety during labor. Perineal trauma during childbirth, especially severe tears such as obstetric anal sphincter injuries (OASIS), is…
- Trial name
- VITAL (NCT07064213)
- Testing
- Behavioral: Educational Video
- Where
- Israel
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Female Sexual Health
A Open-Label, Within-Subject Dose-Escalation Study to Evaluate the Clinical Safety and Pharmacokinetic Profile of a Topical Sildenafil Cream (5% w/w), in Healthy Postmenopausal Women
This is a Phase 1, single center, open-label, within-subject dose-escalation study evaluating the safety and pharmacokinetics of SST-6006 in healthy postmenopausal women.
- Trial name
- NCT02364882
- Testing
- Sildenafil
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Strategic Science & Technologies, LLC
Well-Being, Psychological
Evaluation of Patient-Reported Outcomes Measurement Information System (PROMIS)-29 v2.1 for Postpartum Women
There is no widely used, statistically validated assessment for physical and mental health for the short- to medium-term in a postpartum population.
- Trial name
- NCT06002763
- Testing
- PROMIS-29 v2.1 (Patient-Reported Outcomes Measurement Information System), WHOQoLBREF (World Health Organization Quality of Life Brief Version), EQ-5D-3L1 (not an acronym)
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Vulvovaginal Candidiasis, Bacterial Vaginosis
Study of the Microbiota, Metabolome, and Environmental Toxins in Relation to Reproductive Health in Rwandan Women
The overall objective of this clinical pilot study is to determine at a random sampling time, the vaginal microbiome and metabolome of pregnant women, and to see if infection (bacterial vaginosis, vulvovaginal candidiasis…
- Trial name
- RVMM (NCT02150655)
- Testing
- Lactobacillus GR-1 and Lactobacillus RC-14 oral capsules
- Where
- Rwanda
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Vaginal Health
Topical Estriol for Vaginal Health
The purpose of this Phase I study is to investigate and document the effects of local treatment with a topical estriol cream on the vaginal environment of pre-menopausal women.
- Trial name
- NCT00908570
- Testing
- estriol
- Where
- 2 sites in United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Focus is on Healthy Subjects
Vaginal Detection of Orally Delivered Probiotic Strains in Healthy Women
The purpose of the present study is to obtain more information on the transit of orally ingested probiotics to the vagina.
- Trial name
- VSS2 (NCT07246161)
- Testing
- Probiotic Formula 1, Probiotic Formula 2, Probiotic Formula 3
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Lallemand Health Solutions
Endometriosis, Microbiome Dysbiosis
Trial Evaluating Nutritional Fiber in Digestive Symptoms of Endometriosis
This study is a double-blind, randomized, placebo-controlled study that evaluates the safety and tolerability of a fiber-based dietary supplement and the mechanistic and structure-function effects of that supplement on the gut…
- Conditions
- Endometriosis, Microbiome Dysbiosis, Gastrointestinal Symptoms
- Trial name
- TEND (NCT07875062)
- Testing
- Fiber
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- LOAM Science
Vaginal Health
A Trial to Assess the Pharmacokinetics and Pharmacodynamics of a Novel Synbiotic Oral Supplement for Vaginal Health
A randomized, placebo-controlled trial to assess the Pharmacokinetics and Pharmacodynamics of a novel synbiotic dietary supplement for vaginal health.
- Trial name
- NCT07435350
- Testing
- Vaginal Health Active VV-01
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Radicle Science
HIV-1-infection, Bacterial Vaginoses
Estrogen, Probiotics and Vaginal Health to Prevent HIV Infection in ACB Women
This study will enrol African, Caribbean and Black (ACB) women who are known to have a more diverse vaginal microbiome, higher rates of bacterial vaginosis with lower numbers of protective lactobacilli, and are at increased risk…
- Trial name
- NCT03837015
- Testing
- Estring Vaginal Ring, RepHresh Pro-B
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- McMaster University
Vaginal Microbiota
Collection of Vaginal Microbiota Samples (VAGINOTYPE)
The aim of this study is to collect vaginal microbiota samples from healthy women who are subject to vaginal and urinary infections.
- Trial name
- VAGINOTYPE (NCT06486519)
- Where
- 2 sites in France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Lallemand Health Solutions
Vaginal Health
Effect of Oral Probiotic Yeast on the Composition of the Vaginal Microbiota in Healthy Women
This study is designed to evaluate the impact of oral consumption of the probiotic yeast CNCM I-3856 on healthy vaginal microbiota
- Trial name
- NCT03574844
- Testing
- Saccharomyces cerevisiae, dose 500, Saccharomyces cerevisiae, dose 1000
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lesaffre International
Irritable Bowel Syndrome, Vaginal Health
A Single Group Study to Evaluate the Effects of a Vaginal Probiotic on Vaginal and Digestive Health
This is a virtual single-group study that will last 12 weeks. Participants will take 1 capsule every day, with water. Questionnaires will be completed at baseline, 2 weeks, 4 weeks, and 12 weeks.
- Trial name
- NCT06124313
- Testing
- Vaginal Probiotic
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rael
Vaginal Bleeding, Uterine Cramping
Anticipatory Counseling on LNG-IUS Continuation, Utilization and Satisfaction
This study is a counseling intervention for new LNG-IUS users. The study explores the use of video technology to deliver anticipatory counseling on LNG-IUS side-effects, adjustment periods and bleeding changes to women newly…
- Trial name
- ACCCUSS (NCT02752282)
- Testing
- Anticipatory Counseling, Cancer Screening Guidelines
- Where
- 3 sites in United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- University of Washington
Vaginal Infection
Performance Proof of Product Developed to Detect Abnormal Vaginal pH
This study was designed to validate the color appearance on the NORMA-SENSE gen 3 when comes into contact with vaginal secretions having an elevated pH level
- Trial name
- NCT01542606
- Testing
- NORMA-SENSE
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Common Sense
Allergic Rhinitis, Asthma
Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow
The specific aim of this proposed project is to implement a standard process for integrating MedlinePlus health information prescriptions into the clinic workflow.
- Conditions
- Allergic Rhinitis, Asthma, Back Pain, Benign Prostatic Hypertrophy
- Trial name
- NCT00634608
- Testing
- Health Information Prescription
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia