Clinical trials: Vaginal Prolapse
Sacral Colpopexy, Pelvic Organ Prolapse
Male Sexual Experience and Its Impact on Quality of Life Before and After Their Sexual Partners Undergo Polypropylene Mesh Augmented Pelvic Floor Reconstruction
The correction of the pelvic organ protrusion is aimed at restoring the pelvic floor functional status and ultimately improving the patient's quality of life.
- Trial name
- SEXQ (NCT01320631)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Atlantic Health System
Pelvic Organ Prolapse
Vaginal Orthosis Use After Vaginal Reconstructive Surgery
A novel vaginal orthosis, or splint, made of silicone will be used daily to help support the healing vaginal reconstruction during the post-operative phase from week 2 to week 12.
- Trial name
- NOVa (NCT05812859)
- Testing
- Vaginal Orthosis (COSM Medical)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Cystocele, Uterine Prolapse
Outcomes of Anterior Colporrhaphy Versus Graft Reinforced Anterior Prolapse Repair
The purpose of this study is determine whether grafted anterior vaginal prolapse repair is more effective and associated with less complications than prolapse repair with suture.
- Conditions
- Cystocele, Uterine Prolapse, Urinary Incontinence
- Trial name
- NCT00535301
- Testing
- grafted anterior prolapse repair, sutured anterior vaginal prolapse repair
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Pelvic Organ Prolapse, Postoperative Pain
Does the Use of Bupivacaine Soaked Vaginal Packing Following Vaginal Surgery Decrease Postoperative Pain?
In current practice, packing in the vagina overnight after vaginal surgery is typically used to prevent post-surgical vaginal bleeding.
- Trial name
- NCT03266926
- Testing
- Bupivacaine, Premarin Vaginal cream
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Pelvic Organ Prolapse, Posterior Vaginal Wall Prolapse
Laparoscopic Fascial Duplication Plus Sacral Colpopexy in Posterior Vaginal Prolapse
A Randomized Clinical Trial on Laparoscopic Fascial posterior vaginal duplication with absorbable sutures plus sacral colpopexy mesh placement VS sacral colpopexy isolated for vaginal posterior prolapse
- Trial name
- NCT05252637
- Testing
- Laparoscopic Fascial Posterior Vagina Duplication
- Where
- Italy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Cardinale G. Panico
Quality of Life, Pelvic Floor Distress and Impact Scores
Physical Therapy on Quality of Life and Function Following Vaginal Surgery Reconstructive Surgery
i) The primary objective of this study is to determine if physical therapy improves postoperative quality of life in participants following vaginal reconstructive surgery for pelvic organ prolapse and urinary incontinence.
- Conditions
- Quality of Life, Pelvic Floor Distress and Impact Scores, Sexual Function Scores
- Trial name
- PT and QOL (NCT01403701)
- Testing
- Physical therapy
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Pelvic Organ Prolapse, Prolapse
PDS Versus Prolene as Suture Material for Vaginal Sacrospinous Hysteropexy
Introduction: Pelvic organ prolapse is a common gynecological disease, which about 50% of women develop in the course of their lives. There are many different options for surgical care, e.g.
- Trial name
- NCT05964881
- Testing
- sacrospinous hysteropexy
- Where
- Austria
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Vaginal Prolapse
Using a Sheathed Speculum to Visualize and Access the Cervix In Women With Excessive Vaginal Tissue
The main objective of the study is to assess the effectiveness of the sheathed speculum in providing adequate visualization and access to the cervix in patients with excessive vaginal tissue.
- Trial name
- NCT01409902
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Pelvic Organ Prolapse
Attitude and Success Rate of Women With Pelvic Organ Prolapse on Self-management of Vaginal Pessary
This is a prospective cohort study aims at assessing patient's attitude towards self-management of vaginal pessary, and identifying factors that affect patient's level of acceptance towards self-management.
- Trial name
- NCT06246721
- Testing
- Self-management of vaginal pessary
- Where
- Hong Kong
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Pelvic Organ Prolapse
Evaluation of the Results of Lateral Suspension Surgeries Performed With the V-NOTES (Vaginal-Natural Orifice Transluminal Endoscopic Surgery) Technique
It was aimed to evaluate the quality of life and sexual function of patients by Pre- and postoperative POP-Q (Pelvic Organ Prolapse Quantification) staging and PISQ-12 (Pelvic Organ Prolapse/Urinary Incontinence Sexual…
- Trial name
- NCT05066737
- Testing
- lateral suspension via V-NOTES surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Vaginal Apical Prolapse
Comparing Force of Stream to Retrograde Fill Voiding Trial After Vaginal Apex Suspension
Voiding difficulties are common after prolapse and incontinence surgeries. All patients after vaginal prolapse surgery must complete a voiding trial if they are to be discharged home without a catheter.
- Trial name
- NCT02753920
- Testing
- voiding trial, Foley catheter
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Pelvic Organ Prolapse
Outcomes Following Vaginal Prolapse Repair and Mid Urethral Sling Trial
Pelvic organ prolapse is common among women with a prevalence that has been estimated to be as high as 30%. Prolapse may be corrected by surgery using either a vaginal or abdominal incision.
- Trial name
- OPUS (NCT00460434)
- Testing
- TVT
- Where
- 8 sites in United States
- Volunteers
- 337 people, healthy volunteers welcome
- Sponsor
- NICHD Pelvic Floor Disorders Network
Pelvic Organ Prolapse
Vaginal Axis on Magnetic Resonance Imaging After Laparoscopic Pectopexy Surgery: a Controlled Study
Pelvic organ prolapse (POP) is a major public health concern that adversely affects the physical and psychological well-being of women.
- Trial name
- NCT05876975
- Testing
- laparoscopic pectopexy
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Post-Hysterectomy Vaginal Vault Prolapse
Effects of Deep Breathing Excercises With and Without PMR on Depression & QOL in Females With Hystrectomy
To find out the Effects of deep breathing exercises with and without Progressive Muscle Relaxation Technique on depression and Quality of life in females with hysterotomy
- Trial name
- NCT05460962
- Testing
- Deep breathing excercises, Deep breathing exercises +and progressive muscle relaxation techniques
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Pelvic Organ Prolapse, Prolapse of Vaginal Vault After Hysterectomy
VITOM Study: A Randomized, Controlled Trial.
This is research in which students are queried by questionnaires on their satisfaction with and experience with certain educational practices (use of a camera image projecting during a live surgery) or with pre-recorded video.
- Conditions
- Pelvic Organ Prolapse, Prolapse of Vaginal Vault After Hysterectomy, Bulging of Vaginal Wall, Incontinence
- Trial name
- VITOM (NCT03120689)
- Testing
- Live Surgery using VITOM, Live Surgery without VITOM, Video viewing with VITOM
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Pelvic Organ Prolapse, Urinary Incontinence
Prospective Cohort Study of Robotic Assisted Laparoscopic Sacrocolpopexy Using MPATHY Restorelle Mesh
Robotic approach to sacral colpopexy is a relatively new procedure. The literature is scarce in regard to long term outcome. This advanced procedure is offered at Morristown Memorial.
- Conditions
- Pelvic Organ Prolapse, Urinary Incontinence, Mesh Erosion
- Trial name
- MPATHY (NCT01320618)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Atlantic Health System
Anterior Vaginal Wall Prolapse, Cystocele
Anterior Colporrhaphy Versus Cystocele Repair Using Polypropylene Mesh or Porcine Dermis
The purpose of this study is to evaluate the success rate of cystocele repair using polypropylene mesh or porcine dermis compared to that of anterior colporrhaphy in a prospective randomized fashion.
- Conditions
- Anterior Vaginal Wall Prolapse, Cystocele, Pelvic Organ Prolapse
- Trial name
- OARS (NCT01393171)
- Testing
- Polypropylene mesh (Polyform by Boston Scientific), Porcine Dermis (Pelvicol by CRBard), Anterior Colporrhaphy
- Where
- 2 sites in United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Vaginal Vault Prolapse
Study of Cytrix Use in Pelvic Floor Prolapse Treatment
To evaluate safety and effectiveness of using the fetal bovine dermis (Cytrix) in the treatment of pelvic organ prolapse.
- Trial name
- NCT01244165
- Testing
- Cytrix, Other treatments for pelvic organ prolapse
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Boston Scientific Corporation
Nerve Block, Pain, Postoperative
Pudendal Nerve Block in Vaginal Surgery
The objective of this this randomized controlled study is to determine whether a pudendal nerve block at the time of vaginal surgery is associated with improved postoperative pain control and decrease opioid consumption compared…
- Conditions
- Nerve Block, Pain, Postoperative, Pelvic Floor Disorders, Pelvic Organ Prolapse
- Trial name
- NCT04198714
- Testing
- Pudendal block
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Uterovaginal Prolapse, Prolapse of Vaginal Vault After Hysterectomy
Compare Sacrospinous Fixation Versus High Uterosacral Ligament Fixation for Uterus Vaginal Prolapse III/IV
The purpose of this study is to compare the vaginal sacrospinous colpopexy and high uterosacral colpopexy in the treatment of genital prolapse grade III/IV in women with uterus.
- Conditions
- Uterovaginal Prolapse, Prolapse of Vaginal Vault After Hysterectomy, Complete Tear, Sacrospinous Ligament, Uterosacral Ligament; Rupture
- Trial name
- NCT01347021
- Testing
- sacrospinous colpopexy versus high uterosacral colpopexy
- Where
- Brazil
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo