Clinical trials: Vaginal Surgery
Appendicitis, Cholelithiasis
Minimally Invasive Surgery: Using Natural Orfices
This is an observational study of pain and outcomes from females undergoing transvaginal NOTES removal of their appendix or gallbladder.
- Conditions
- Appendicitis, Cholelithiasis, Gallstones
- Trial name
- NOTES (NCT00530998)
- Testing
- Transvaginal Appendectomy, Transvaginal Cholecystectomy
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of California, San Diego
Stress Incontinence, Female
Vaginal Elasticity Assessment Before and After Surgical Repair for Urinary Stress Incontinence.
Female patients with USI will be evaluated for vaginal elasticity using vaginal tactile imaging both before and after surgery for the repair of the USI.
- Trial name
- NCT03301818
- Testing
- Vaginal tactile imager
- Where
- Israel
- Volunteers
- 23 people
- Sponsor
- Rambam Health Care Campus
Abortion, Second Trimester
24-hour Mifepristone and Buccal Versus Mifepristone and Vaginal Misoprostol for Cervical Preparation for D&E
This study aims to compare mifepristone and buccal misoprostol to mifepristone and vaginal misoprostol for cervical preparation for second trimester dilation and evacuation (D\&E).
- Trial name
- NCT03134183
- Testing
- Vaginal Misoprostol, Buccal Misoprostol
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Female Genital Prolapse
Single Incision Transvaginal Mesh in Treatment of Posterior Vaginal Wall Prolapse
Definition: To find out complications, objective and subjective outcomes of patients with symptomatic posterior vaginal wall prolapse undergoing posterior mesh operation in nine Finnish hospitals during September 2010 and August…
- Trial name
- NCT02092623
- Testing
- Transvaginal posterior mesh
- Where
- Finland
- Volunteers
- 111 people
- Sponsor
- Turku University Hospital
Pelvic Organ Prolapse
Vaginal Tactile Imaging for the Assessment of Pelvic Organ Prolapse Repair Efficiency
Female patients with POP will be evaluated for vaginal elasticity using vaginal tactile imaging both before and after surgery for the repair of the POP.
- Trial name
- NCT03311685
- Testing
- vaginal tactile imager
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Rambam Health Care Campus
Fibroids
Tissue Removal During Hysterectomy: The Effect of Vaginal Versus Abdominal Morcellation on Surgical Outcomes
In this study the investigators will perform a randomized trial to compare the surgical outcomes of vaginal versus abdominal morcellation of the uterus during hysterectomy.
- Trial name
- NCT02703246
- Testing
- abdominal morcellation, vaginal morcellation
- Where
- United States
- Sponsor
- George Washington University
Vaginal Vault Prolapse
Traditional Vaginal Surgery VS Autologous Tissue in Pelvic Floor Repair
The goal of this randomized, non blind, one center study is to compare the efficacy of vNOTES (vaginal natural orifice transluminal surgery) and traditional vaginal operation between the two groups by determining the risk of…
- Trial name
- PREFAP (NCT05628831)
- Testing
- vNOTES suspension with autologous tissue, Vaginal surgery
- Where
- Croatia
- Volunteers
- 56 people
- Sponsor
- General Hospital Zadar
Vulvar Dysplasia, Vaginal Dysplasia
A Randomized Trial of Surgical Treatments for Vulvar and Vaginal Dysplasia
1. To compare the recurrence rate between the use of laser vaporization and ultrasonic surgical aspiration in the treatment of vulvar and vaginal dysplasias 2.
- Trial name
- NCT00394758
- Testing
- CO2 laser surgery, ultrasonic surgical aspiration
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University Hospitals Cleveland Medical Center
Other Abnormal Uterine and Vaginal Bleeding
Permanent Occlusion of Uteine Arteies in Management of Abnormal Uterine Bleeding
Prospective observational interventional study , The study done in two phases: 1. Phase one from October 2011to May 2012 pilot study including twenty nine (29) premenopausal patients followed up for six months 2.
- Trial name
- NCT05423067
- Testing
- bilateral permanent occlusion of uterine arteries
- Where
- Egypt
- Volunteers
- 116 people
- Sponsor
- Mansoura Integrated Fertility Center
Musculoskeletal Pain, Musculoskeletal Injury
Surgeon Core-strengthening Program as a Modifier for Exertion Associated With Vaginal Surgery
Work-related musculoskeletal pain and injury is a growing concern in surgery. Vaginal surgery has unique ergonomic risks, but no studies have addressed the potential for an exercise regimen to reduce physical strain by vaginal…
- Trial name
- SCORE (NCT06525701)
- Testing
- Execise Group, Control Group
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Loyola University
Infection Control / Methods, Surgical Site Infection (SSI)
Preoperative Clindamycin Vaginal Cream Versus Vaginal Cleansing With Povidone-iodine on Postoperative Infections After Cesarean Section
To evaluate the effects of preoperative prophylactic administration of clindamycin vaginal cream compared to preoperative vaginal cleansing using a 10% povidone-iodine solution on postpartum infectious morbidity.
- Trial name
- SSI (NCT07474194)
- Testing
- Clindamycin vaginal cream, Vaginal preparation with povidone- iodide solution 10 %
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Beni-Suef University
Uterine Fibroids, Hysterectomy
Predictors of Success and Failure of v-NOTES Hysterectomy for Large and Very Large Uteri
Uterine fibroids are the most common benign tumors in women of reproductive age and are a major indication for hysterectomy. This retrospective, single-center observational study aims to identify factors associated with the…
- Conditions
- Uterine Fibroids, Hysterectomy, Vaginal Natural Orifice Transluminal Endoscopic Surgery (v-NOTES)
- Trial name
- PRE v-NOTES (NCT07895953)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Strasbourg, France
Anesthetic Regional Techniques for Vaginal Surgeries
Regional Anesthesia
Both techniques are efficacious for sacral anesthesia during vaginal surgeries. Dural puncture epidural technique allows partial confirmation of epidural catheter placement.
- Trial name
- NCT04933500
- Testing
- Whitacre spinal needle
- Where
- Egypt
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Reham Ali Abdelhaleem Abdelrahman
Gynecologic Surgical Procedures
Barbed vs Standard Suture for Laparoscopic Vaginal Cuff Closure
Total laparoscopic hysterectomy is a procedure that is performed each time more often. One of the problems described for this procedure has to do with the closure of the vaginal vault, increased surgical time when suture…
- Trial name
- NCT03038945
- Testing
- 2/0 barbed suture, 0/0 Vicryl suture
- Where
- Colombia
- Volunteers
- 150 people
- Sponsor
- CES University
Urinary Incontinence, Stress, Uterine Prolapse
Colpopexy and Urinary Reduction Efforts (CARE) Protocol
Pelvic organ prolapse occurs when the muscles holding pelvic organs (e.g., the uterus or bladder) weaken and the organs fall or slide down into the vagina. Pelvic organ prolapse can be corrected with surgery.
- Conditions
- Urinary Incontinence, Stress, Uterine Prolapse, Vaginal Prolapse
- Trial name
- CARE (NCT00065845)
- Testing
- Burch urethropexy at time of sacrocolpopexy
- Where
- 7 sites in United States
- Volunteers
- 322 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Prolapse Pelvic, Hysterectomy
Vaginal Natural Orifice Transluminal Endoscopic (vNOTE) Hysterectomy With Uterosacral Suspension
As the adoption of Vaginal natural orifice transluminal endoscopic surgery (vNOTES) expands, attention is shifting from feasibility studies to the refinement of surgical steps that optimize long-term pelvic health.
- Trial name
- VENUS (NCT07413861)
- Testing
- Uterosacral suspension, Hysterectomy by vNOTES approach
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Hysterectomy, Minimal Invasive Surgery
Comparative Study of LAVH and Minilaparotomy Hysterectomy
Minilaparotomy hysterectomy (MLH) relies on the simplicity of traditional open technique of abdominal hysterectomy, imparts cosmesis and faster recovery of laparoscopic hysterectomy yet avoids the long learning curve, cost of…
- Conditions
- Hysterectomy, Minimal Invasive Surgery, Benign Gynecologic Neoplasm
- Trial name
- LAVH (NCT03548831)
- Volunteers
- 52 people
- Sponsor
- Manipal University
Stress Urinary Incontinence
Retropubic vs. Transobturator Tension-free Vaginal Tape
The so-called tension-free vaginal tape (TVT), first described in Sweden in 1996, has become a standard operation worldwide for the treatment of women with stress urinary incontinence.
- Trial name
- NCT00441454
- Testing
- Transobturator Tension-free vaginal tape (TVT-O), Retropubic Tension-free vaginal tape (TVT)
- Where
- 4 sites in Austria
- Volunteers
- 564 people
- Sponsor
- Austrian Urogynecology Working Group (AUWG)
Pelvic Organ Prolapse, Prolapse
Early Feasibility Study of the Reia Vaginal Pessary
This is an early feasibility open-label non-randomized trial to obtain preliminary information about the function and effectiveness of a novel vaginal pessary for the use in women who suffer from symptoms of pelvic organ prolapse…
- Trial name
- NCT04275089
- Testing
- Reia Vaginal Pessary
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Reia, LLC
Pelvic Organ Prolapse
Composite Outcomes of Mesh vs Suture Techniques for Prolapse Repair: A Randomized Controlled Multicentre Trial
This is a Canadian, multi-centre, double-blind randomized controlled trial of an innovative vaginal surgery technique for correction of pelvic organ prolapse (POP) in women.
- Trial name
- COMET (NCT02965313)
- Testing
- SSLS Procedure, BSSVF-M Procedure
- Where
- Canada
- Volunteers
- 358 people
- Sponsor
- University of British Columbia