Clinical trials: Vaginal Surgery
Musculoskeletal Pain, Musculoskeletal Injury
Surgeon Core-strengthening Program as a Modifier for Exertion Associated With Vaginal Surgery
Work-related musculoskeletal pain and injury is a growing concern in surgery. Vaginal surgery has unique ergonomic risks, but no studies have addressed the potential for an exercise regimen to reduce physical strain by vaginal…
- Trial name
- SCORE (NCT06525701)
- Testing
- Execise Group, Control Group
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Loyola University
Pelvic Organ Prolapse
Comparison of Vaginal Axis on MRI in Alternative Apical Prolapse Surgeries to Sacrocolpopexy
Sacrocolpopexy remains the preeminent modality in addressing apical prolapse surgically. Nevertheless, amplified morbidity rates within cohorts characterized by obesity and advanced age constrain the advantages conferred by the…
- Trial name
- NCT06072456
- Testing
- laparoscopic lateral suspension, laparoscopic pectopexy, Sacrospinous ligament fixation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Quality of Recovery, Same Day Surgery
Dexamethasone Administration To Improve Patient Recovery In Ambulatory Vaginal Prolapse Surgery: Is There A Role?
To the investigators knowledge there are no studies in the literature evaluating the effect of Dexamethasone administration on patients undergoing outpatient vaginal prolapse surgeries.
- Conditions
- Quality of Recovery, Same Day Surgery, Nausea and Vomiting, Postoperative, Vaginal Prolapse
- Trial name
- NCT03338400
- Testing
- Dexamethasone, Normal saline
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- The Cleveland Clinic
Uterovaginal Prolapse
Study of Uterine Prolapse Procedures - Randomized Trial
The primary purpose of this randomized clinical trial is to compare the effectiveness and safety of two transvaginal apical suspension strategies for uterovaginal prolapse: a mesh augmented hysteropexy versus vaginal hysterectomy…
- Trial name
- SUPeR (NCT01802281)
- Testing
- Uterosacral ligament suspension, Uphold® LITE
- Where
- 8 sites in United States
- Volunteers
- 183 people
- Sponsor
- NICHD Pelvic Floor Disorders Network
Surgical Repair of Middle Compartment Prolapse (Vaginal Vault or Uterine Prolapse) With or Without Cystocele
Safety and Efficacy of a Transvaginal Suture Capturing Mesh Device
To perform a clinical safety and efficacy assessment of the Uphold LITE system for pelvic organ prolapse in a prospective multicenter, single cohort study.
- Trial name
- NCT01823055
- Testing
- Transvaginal suture capturing mesh device
- Volunteers
- 214 people
- Sponsor
- Karolinska Institutet
Rectovaginal Fistula, Anovaginal Fistula
Feasibility and Safety of Additional Injection of Autologous Platelet-rich Stroma to Surgical Treatment of Rectovaginal Fistulas
Is the addition of platelet-rich stroma (PRS) injection, a form of autologous call therapy, to surgical treatment for rectovaginal fistula feasible and safe? The primary endpoints of this study are feasibility and safety until 12…
- Trial name
- PRS-RVF (NCT06798935)
- Testing
- autologous platelet-rich stroma
- Where
- Netherlands
- Volunteers
- 21 people
- Sponsor
- Erasmus Medical Center
Pelvic Organ Prolapse (POP), Pelvic Organ Prolapse Vaginal Surgery
Urinary Continence After Vaginal Surgery for Genital Prolapse in the Spanish Population.
Surgical correction of pelvic organ prolapse (POP) may be associated with the development of postoperative stress urinary incontinence (SUI).
- Conditions
- Pelvic Organ Prolapse (POP), Pelvic Organ Prolapse Vaginal Surgery, Urinary Incontinence (UI)
- Trial name
- NCT07628036
- Testing
- Vaginal surgery for pelvic organ prolapse
- Where
- 4 sites in Spain
- Volunteers
- 1,042 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Hysterectomy, Minimal Invasive Surgery
Comparative Study of LAVH and Minilaparotomy Hysterectomy
Minilaparotomy hysterectomy (MLH) relies on the simplicity of traditional open technique of abdominal hysterectomy, imparts cosmesis and faster recovery of laparoscopic hysterectomy yet avoids the long learning curve, cost of…
- Conditions
- Hysterectomy, Minimal Invasive Surgery, Benign Gynecologic Neoplasm
- Trial name
- LAVH (NCT03548831)
- Volunteers
- 52 people
- Sponsor
- Manipal University
Surgical Site Infection, Vaginal Cuff Cellulitis
Prevention of Vaginal Cuff Infection After Hysterectomy by Addition of Vaginal Clindamycin
This study seeks to determine ways to reduce the hospitals surgical site infection rate during hysterectomy operations.
- Conditions
- Surgical Site Infection, Vaginal Cuff Cellulitis, Bacterial Vaginosis
- Trial name
- NCT07888101
- Testing
- Clindamycin Vaginal Gel
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- Baylor Research Institute
Pelvic Organ Prolapse, Prolapse
Early Feasibility Study of the Reia Vaginal Pessary
This is an early feasibility open-label non-randomized trial to obtain preliminary information about the function and effectiveness of a novel vaginal pessary for the use in women who suffer from symptoms of pelvic organ prolapse…
- Trial name
- NCT04275089
- Testing
- Reia Vaginal Pessary
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Reia, LLC
Pelvic Organ Prolapse, Urinary Incontinence
Continence After Vaginal Prolapse Surgery
Urinary incontinence after surgical correction of pelvic organ prolapse (POP) could occur. This is a condition that decreases both patients' satisfaction and quality of life.
- Trial name
- NCT05312047
- Testing
- Pelvic organ prolapse surgery
- Where
- 14 sites in Spain
- Volunteers
- 609 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Stress Urinary Incontinence
Quality-of-Life Outcomes After Autologous Fascial Sling and TVT: a Prospective Randomized Trial
The objective of the study was to evaluate the impact AFS and TVT procedures on quality-of-life in incontinent women.
- Trial name
- NCT00565838
- Testing
- AFS and TVT
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Pelvic Organ Prolapse
A Multi-center Registry Study: The Follow-up the Complications for Trans-vaginal Mesh Surgery
This is a multi-center, prospective, observational, hospital-based registry of pelvic organ prolapse(POP) patients who having trans-vaginal mesh implantation with 12 month and 36 month follow-up.To investigate the incidence of…
- Trial name
- NCT04025047
- Where
- China
- Volunteers
- 4,147 people
- Sponsor
- Peking Union Medical College Hospital
Surgery, Knowledge, Attitudes, Practice
What is the Impact of the Presence of a Support Person on Informed Consent
In practice, the Investigators recommend that patients bring a family member or close friend to their pre-operative appointment to help with patient anxiety, comprehension, and informed decision-making.
- Conditions
- Surgery, Knowledge, Attitudes, Practice, Prolapse, Vaginal, Urinary Incontinence
- Trial name
- NCT03966469
- Testing
- Preoperative support person present, Patient Present Only
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Hartford Hospital
Hysterectomy, Hysterectomy, Benign Uterine Diseases
VNOTES and Vaginal Hysterectomy for Benign Indications
This study aimed to compare the surgical outcomes of Vaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) and conventional vaginal hysterectomy (VH) for benign gynecological conditions.
- Conditions
- Hysterectomy, Hysterectomy, Benign Uterine Diseases, Hysterectomy, Vaginal
- Trial name
- NCT06776718
- Testing
- vNOTES, vaginal hysterectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Urinary Incontinence, Stress
Complications of Mesh Procedures for Stress Urinary Incontinence
Complications from mesh procedures (i.e. insertion of tension-free vaginal tapes (TVT), trans-obturator tapes (TOT) and suprapubic slings (SS)) used during surgical treatment of stress urinary incontinence have caused major…
- Trial name
- SUI-mesh (NCT02850120)
- Testing
- Tension-free vaginal tape (TVT), Trans-obturator tape (TOT), Suprapubic sling (SS)
- Volunteers
- 101,081 people
- Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
Gynecologic Surgical Procedures
Barbed vs Standard Suture for Laparoscopic Vaginal Cuff Closure
Total laparoscopic hysterectomy is a procedure that is performed each time more often. One of the problems described for this procedure has to do with the closure of the vaginal vault, increased surgical time when suture…
- Trial name
- NCT03038945
- Testing
- 2/0 barbed suture, 0/0 Vicryl suture
- Where
- Colombia
- Volunteers
- 150 people
- Sponsor
- CES University
Pain, Postoperative
Preemptive Local Anesthesia in Vaginal Surgery
Preemptive analgesia is an intervention which provides an anesthetic prior to initiating a painful stimulus. This trial is examining the effects of a local anesthetic given at the point of innervation prior to performing a…
- Trial name
- NCT00318292
- Testing
- bupivacaine and epinephrine
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Mayo Clinic
Anterior Prolapse Surgery Using the Transobturator Repair by Vaginal Plastron
Transobturator Repair by Vaginal Plastron
The autologous vaginal route consists of repairing the genital prolapse through the vagina using the patient's tissues without a prosthesis. Vaginal prostheses are actually currently prohibited in France [1, 2].
- Trial name
- CYSPTO (NCT05741567)
- Testing
- correction of anterior prolapse
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospices Civils de Lyon
Pelvic Organ Prolapse (POP), Pelvic Organ Prolapse Vaginal Surgery
A Comparison Between Vaginal Sacrospinous Ligament Fixation and Laparoscopic Uterosacral Ligament Suspension as a Uterine Preserving Surgery for Pelvic Organ Prolapse
The investigators present a literature review evaluating the current place of sacrospinous hysteropexy in the surgical management of pelvic organ prolapse.
- Conditions
- Pelvic Organ Prolapse (POP), Pelvic Organ Prolapse Vaginal Surgery, Hysterectomy
- Trial name
- POP-Q USS USLS (NCT06982157)
- Where
- Israel
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center