Clinical trials: Vaginal Surgery
Vulvovaginal Atrophy, Menopause
RF and PEMF for Treatment of Vaginal Laxity and Mons Pubis and Labia for Improvement of Skin Laxity
Twelve month extension of a previous study of Multi-Polar RF and PEMF technologies for the treatment of vaginal laxity and for the treatment of the mons pubis and labia for improvement in skin laxity.
- Conditions
- Vulvovaginal Atrophy, Menopause, Menopause Surgical
- Trial name
- NCT04210583
- Testing
- Vulvovaginal Treatment
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Venus Concept
Postoperative Infection
Povidone-iodine Versus Normal Saline Solution in Vaginal Cleansing in Laparoscopy
Laparoscopy is a minimally invasive method used for diagnostic and therapeutic purposes. It allows surgeons to take a look on the abdominal and pelvic organs.
- Trial name
- NCT02591251
- Testing
- Povidone-iodine solution, Normal saline solution
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Stress Urinary Incontinence
Reducing Early Urinary Disorders After Stress Incontinence Surgery: The Role of Vaginal Wall Tension.
The progress in surgical procedures for treating female stress urinary incontinence has led to the development of tension-free techniques such as the trans-obturator tape (TOT).
- Trial name
- NCT06292702
- Testing
- Traditional Burch colposuspension, Modified Burch colposuspension
- Where
- Syria
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Damascus University
Missed Abortion
Buccal Versus Vaginal Misoprostol in Surgical Termination of the First Trimester Missed Abortion in Erbil
The purpose of this study is to determine the effectiveness of buccal misoprostol and comparing this with vaginal route of the same drug.
- Trial name
- NCT00892229
- Testing
- Misoprostol (given buccally), Misoprostol (given vaginally)
- Where
- Iraq
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hawler Medical University
Endometrial Adenocarcinoma, Endometrial Cancer
Comparison of Sentinel Lymph Node Applications in Endometrial Cancer Cases Performed With Vaginal Natural Orifice Transluminal Endoscopic Surgery (V-NOTES) and Conventional Laparoscopy
Endometrial cancer is a common cancer in women, and surgery is usually the first step in treatment. During surgery, doctors often check nearby lymph nodes to see if the cancer has spread.
- Trial name
- V-COSMOS (NCT07583329)
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Cukurova University
Opioid Use, Surgical Recovery
Paracervical Injection and Opioid Use After Vaginal Hysterectomy for Prolapse
The goal of the study to see if giving a numbing medicine around the cervix (called a paracervical block) during vaginal hysterectomy with prolapse repair helps people feel less pain and need fewer strong pain medicines…
- Conditions
- Opioid Use, Surgical Recovery, Vaginal Hysterectomy, Prolapse Pelvic
- Trial name
- NCT07213635
- Testing
- Bupivacaine-epinephrine, Normal saline
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Obstetric Fistula, Fistula
Effectiveness and Acceptability of Insertable Devices for Obstetric Fistula Management
The investigators propose a clinical trial and nested qualitative study to 1) quantify the effectiveness of an insertable vaginal cup to manage fistula urinary incontinence, 2) examine user and implementer acceptability, and 3)…
- Conditions
- Obstetric Fistula, Fistula, Fistula, Urinary, Fistula, Vaginal
- Trial name
- COPE (NCT05444504)
- Testing
- Cup, Cup+
- Where
- 3 sites in Ghana, Kenya
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
Surgery
Ultrasound Evaluation for Improving Patient Selection in vNOTES
Vaginal Natural Orifice Transluminal Endoscopic Surgery (vNOTES) is an emerging field in minimally invasive surgery. An international consensus-based statement was recently published to help guide the basis for adopting vNOTES…
- Trial name
- PUP-VNOTES (NCT05623514)
- Testing
- Trans-vaginal ultrasound
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Endosalpingiosis
Tight Vaginoscopy: a Simplified Novel Technique for a Better Vaginal Surgery
Bivalve vaginal speculum insertion is a basic final step of vaginal examination. Unfortunately, it can't be inserted in young girls, virgins, nulliparous women with narrow vagina, women with vaginismus or patients with a history…
- Trial name
- NCT03024242
- Testing
- Tight vaginoscope
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Assiut University
Other Abnormal Uterine and Vaginal Bleeding
Permanent Occlusion of Uteine Arteies in Management of Abnormal Uterine Bleeding
Prospective observational interventional study , The study done in two phases: 1. Phase one from October 2011to May 2012 pilot study including twenty nine (29) premenopausal patients followed up for six months 2.
- Trial name
- NCT05423067
- Testing
- bilateral permanent occlusion of uterine arteries
- Where
- Egypt
- Volunteers
- 116 people
- Sponsor
- Mansoura Integrated Fertility Center
Pain Vulva
Application of Cheek Acupuncture in Vaginal Tightening Surgery
A large number of studies have shown that acupuncture can reduce perioperative pain in patients. Cheek acupuncture therapy is a new acupuncture treatment, which belongs to the microneedle system, that is, acupuncture at specific…
- Trial name
- NCT06587711
- Testing
- acupuncture treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Abdominal Hysterectomy
The Application of Vaginal Manipulator in Abdominal Hysterectomy Operations
If a vaginal manipulator is used for abdominal hysterectomy, the vagina can be cut and separated from the cervix without cutting the Cardinal and Sacrouterine ligaments and protecting the top of the vaginal tissue (Portio…
- Trial name
- NCT05420662
- Testing
- Manipulation of vagina during abdominal hysterectomy operation, Classical conventional abdominal hysterectomy operation
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people
- Sponsor
- Kocaeli University
Vaginoscopy
Simplification of Vaginoscopic Surgery Using a Self-retaining External Vulvar Sheet (Darwish Sheet)
Vaginoscopic examination is usually difficult due to continuous leakage of the distension medium from the introitus. This study aims to assess the effectiveness and success of performing diagnostic or operative vaginoscopic…
- Trial name
- Darwish sheet (NCT04387123)
- Testing
- Vaginoscopy
- Where
- Egypt
- Volunteers
- 37 people
- Sponsor
- Woman's Health University Hospital, Egypt
Vaginal Wall Prolapse
Surgical Repair of Vaginal Wall Prolapse Using Gamma Irradiated Amniotic Membrane as a Scaffold
The surgical repair of vaginal wall prolapse continues to remain one of the most difficult challenges in female pelvic floor reconstruction. The recurrence rate after standard colporrhaphy ranges from 40-60 %.
- Trial name
- NCT05355623
- Testing
- Vaginal Repair
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Egymedicalpedia
Pelvic Floor Disfunction, Urogynecologic Surgery
Comparison of Reciprocal-crossover McCall Culdoplasty and Conventional McCall Culdoplasty
In this study, our aim is to compare pelvic floor examination findings and quality-of-life satisfaction data between a group that underwent "reciprocal-suture McCall culdoplasty with simultaneous fixation of the ovarian proper…
- Trial name
- NCT07903610
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Ankara City Hospital Bilkent
Postoperative Pain
Use of Cyclobenzaprine After Vaginal Surgery
The management of post-operative pain in patients after vaginal surgery provides many unforeseen challenges. Although vaginal surgery is considered a minimally invasive approach for the repair of pelvic floor prolapse and urinary…
- Trial name
- NCT01081990
- Testing
- cyclobenzaprine
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Genital Prolapse
Vaginal Estriol Before and Vaginal Surgery for Prolapse
The purpose of this study is to determine whether the vaginal estriol before vaginal surgery for pelvic statics disorders is more efficacy of no estriol treatment on vaginal health and quality of life.
- Trial name
- VSaE (NCT02906111)
- Testing
- estriol, vaginal surgery
- Volunteers
- 88 people
- Sponsor
- Salvatore Caruso
Ectopic Pregnancy
Comparison of vNOTES and Laparoscopic Salpingectomy in the Surgical Treatment of Ectopic Pregnancy
This study compares vNOTES salpingectomy and laparoscopic salpingectomy in the treatment of ectopic pregnancy, focusing on outcomes such as operative time, postoperative pain, and recovery.
- Trial name
- vNOTES (NCT07057115)
- Testing
- vNOTES Salpingectomy Group., Laparoscopic Salpingectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Pelvic Organ Prolapse, Pelvic Organ Prolapse (POP)
Accelerometer Measured Early Recovery After Prolapse Surgery
The AccelERate study will evaluate the physical recovery of patients who have undergone Pelvic Organ Prolapse (POP) surgery. This will be evaluated via a self-reported recovery questionnaire completed daily.
- Conditions
- Pelvic Organ Prolapse, Pelvic Organ Prolapse (POP), Pelvic Organ Prolapse Vaginal Surgery, Pelvic Organ Prolapse, Patient Education
- Trial name
- AccelERate (NCT07218016)
- Testing
- Postoperative Exercise regimen
- Where
- 7 sites in United States
- Volunteers
- 288 people
- Sponsor
- NICHD Pelvic Floor Disorders Network
Magnetic Resonance Imaging, Hysteroscopy
Hysteroscopic Evaluation and the Clinical Outcomes of Vaginal Repair of Cesarean Section Scar Defects
Cesarean section scar defects (CSDs) are one of the long-term complications following cesarean section. They can be detected by transvaginal sonography, hysterosalpingography, sonohysterography and magnetic resonance imaging…
- Trial name
- CSD (NCT05858931)
- Testing
- vaginal repair
- Where
- China
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine