Clinical trials: Vaginal Surgery
UTERINE LEIOMYOMA
Influence of Aromatase Inhibitors and GnRH Analogs to Treat Uterine Leiomyoma by Vaginal Hysterectomy
The investigators aimed to assess if use of aromatase inhibitors could decrease volume of uterine leiomyoma and cause same percentage of adverse effects during its use compared to GnRH analogs.
- Trial name
- NCT01280045
- Testing
- VAGINAL HYSTERECTOMY
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Sexual Function
Evaluating Sexual Function After Vaginal Repair With Perineorrhaphy
This is a single center, double-blind, randomized controlled trial evaluating the change in sexual function in women undergoing vaginal repair for pelvic organ prolapse.
- Trial name
- FaVR (NCT01779739)
- Testing
- Perineorrhaphy
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- Wake Forest University Health Sciences
Hysterectomy
Utility of the GoPro Hero 3 Camera as an Educational Tool For Vaginal Surgical Skills
Utilization of the GoPro camera to facilitate vaginal surgical education among residents and medical students
- Trial name
- NCT02669537
- Testing
- GoPro Camera
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Urinary Incontinence, Urinary Stress Incontinence
Pregnancy After Tension-free Vaginal Tape and Other Mid-urethral Sling Procedures
The purpose of this study is to determine the interactions between pregnancy and urinary stress incontinence in women with a mid-urethral sling (MUS).
- Conditions
- Urinary Incontinence, Urinary Stress Incontinence, Pregnancy Complications
- Trial name
- PregnanT (NCT02999347)
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Oslo University Hospital
Pelvic Organ Prolapse
Surgical Intervention With DermaPure vs Native Tissue in Pelvic Organ Prolapse
Comparing FDA-approved DermaPure with patient's own native tissue surgically for diagnosis of pelvic organ prolapse.
- Trial name
- NCT03939715
- Testing
- DermaPure®, native tissue
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Colorado Pelvic Floor Consultants
Vaginal Hysterectomy, Suburethral Slings
Sedation With Dexmedetomidine Versus Remifentanil in Urogynecological Surgery Under Spinal Anaesthesia
Neuraxial blocks are usually used as an anaesthetic method for urogynecological surgeries. In most patients under regional anaesthesia, premedication is given for reducing anxiety.
- Trial name
- NCT03883347
- Testing
- Dexmedetomidine, Remifentanil
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- University of Athens
Vaginal Hysterectomy, Pelvic Organ Prolapse Vaginal Surgery
The Effect of Physiotherapy Treatment Following Gynaecological Surgery
Optimal pelvic floor muscle function is known to assist bladder and bowel function and control, pelvic organ support, as well as other areas of health.
- Trial name
- NCT00222326
- Testing
- Pelvic floor muscle training and lifestyle modification
- Where
- Australia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Melbourne
Vaginal Fistula, Vesico Vaginal Fistula
Feasibility of the Menstrual Cup for VVF
This study examines the feasibility and acceptability of the vaginal menstrual cup for short-term management of vesicovaginal fistula (VVF) among 11 women seeking treatment at a health facility in Ghana.
- Conditions
- Vaginal Fistula, Vesico Vaginal Fistula, Obstetric; Injury
- Trial name
- FMCVVF (NCT03414060)
- Testing
- Menstrual Cup
- Where
- Ghana
- Volunteers
- 11 people
- Sponsor
- University of Ghana Medical School
Rectocele
Trial to Determine Which of Two Surgical Techniques Works Better to Correct Vaginal Bulging
Women with vaginal bulging who are undergoing laparoscopic sacrocolpopexy at Clarian Health are eligible to enroll in this study.
- Trial name
- NCT00988975
- Testing
- Insertion of pelvicol graft
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Urogynecology Associates, Indiana
Gynecological Surgery
Assessment of Changes in Vaginal Microbiota Profiles Before and After Vaginal Urogynecologic Surgery
Several studies have shown interactions between vaginal microbiota and post-surgical evolution. A study conducted by our team showed a tendency for patients with complications to have a greater diversity of vaginal microbiota.
- Trial name
- VAGIBIOTE (NCT04301401)
- Testing
- Vaginal swabs, Stool samples, Urine samples
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Pelvic Organ Prolapse, Gynecologic Disorders
Comparison of Learning Curves for Two Different Techniques in Vaginal Hysterectomy
Randomized prospective monocentric interventional study to compare learning curves for traditional vaginal hysterectomy and vaginal hysterectomy performed by bipolar coagulation comparing short-term outcomes for both procedures.
- Conditions
- Pelvic Organ Prolapse, Gynecologic Disorders, Surgery
- Trial name
- NCT06220253
- Testing
- vaginal hysterectomy by bipolar vessels sealing, vaginal hysterectomy by traditional technique
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Hysterectomy, Vaginal
Hysterectomy by Transvaginal Natural Orifice Transluminal Endoscopic Surgery Versus or Laparoscopic Hysterectomy
In France, there are approximately 62,000 hysterectomies per year, 70% of which are benign. It is the most frequent surgical procedure in gynecology.
- Trial name
- vNOTESHC (NCT05884658)
- Testing
- vNOTES : natural vaginal orifice transluminal endoscopic system for hysterectomies, laparoscopic hysterectomy
- Where
- 6 sites in France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Hysterectomy, Surgery
Vaginal Cuff Closure by Modification of the Bakay Technique in Total Laparoscopic Hysterectomy
Modified Bakay technique offers a novel colpotomy and cuff closure technique for total laparoscopic hysterectomy (TLH), and consists of placing a single continuous running purse-string suture facilitating the cuff closure before…
- Conditions
- Hysterectomy, Surgery, Laparoscopy
- Trial name
- NCT05080114
- Testing
- Modified Bakay technique (MT), Standard technique (ST)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 148 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Healing of the Wound After Rectovaginal Fistula Surgery
the Method of Cotton Padding Promoting the Rectovaginal Fistula Surgery
The method of Cotton Padding (mCP) was summarized by combining with many years clinical experience and the traditional ancient books.The mCP could be used in Rectovaginal Fistula (RVF) post operation effectively,in order to…
- Trial name
- NCT05138965
- Testing
- the mCP with alginates dressing, only alginates dressing
- Where
- 3 sites in China
- Volunteers
- 20 people
- Sponsor
- China Academy of Chinese Medical Sciences
Postoperative Urinary Retention, Sacrospinous Vaginal Vault Suspension
Effect of Tizanidine on Postoperative Urinary Retention After Sacrospinous Suspension
Postoperative urinary retention has been defined as the inability to void despite having fluid in the bladder during the postoperative period.
- Conditions
- Postoperative Urinary Retention, Sacrospinous Vaginal Vault Suspension, Reconstructive Pelvic Surgery
- Trial name
- NCT06258785
- Testing
- Tizanidine
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Endometrial Cancer
External-Beam Radiation Therapy Compared With Vaginal Brachytherapy After Surgery for Stage I Endometrial Cancer
RATIONALE: External-beam radiation therapy uses high-energy x-rays to kill tumor cells. Implant radiation therapy uses radioactive material placed directly into or near a tumor to kill tumor cells.
- Trial name
- PORTEC-2 (NCT00376844)
- Testing
- External Beam Radiation Therapy, Vaginal Brachytherapy
- Where
- Netherlands
- Volunteers
- 427 people
- Sponsor
- Leiden University
Educational Problems
Comparing Proficiency of Laparoscopic Vaginal Cuff Suturing After Laparoscopic Training in Surgically Naive Students
Surgically naive premedical and medical students were trained on two different laparoscopic simulation trainers, then tested on the same vaginal cuff suturing model.
- Trial name
- NCT04524988
- Testing
- Laparoscopic Simulation Training
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Northwestern University
Vaginal Vault Prolapse
Traditional Vaginal Surgery VS Autologous Tissue in Pelvic Floor Repair
The goal of this randomized, non blind, one center study is to compare the efficacy of vNOTES (vaginal natural orifice transluminal surgery) and traditional vaginal operation between the two groups by determining the risk of…
- Trial name
- PREFAP (NCT05628831)
- Testing
- vNOTES suspension with autologous tissue, Vaginal surgery
- Where
- Croatia
- Volunteers
- 56 people
- Sponsor
- General Hospital Zadar
Nerve Block, Pain, Postoperative
Pudendal Nerve Block in Vaginal Surgery
The objective of this this randomized controlled study is to determine whether a pudendal nerve block at the time of vaginal surgery is associated with improved postoperative pain control and decrease opioid consumption compared…
- Conditions
- Nerve Block, Pain, Postoperative, Pelvic Floor Disorders, Pelvic Organ Prolapse
- Trial name
- NCT04198714
- Testing
- Pudendal block
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Vaginal Surgery
Effect of Pain Vigilance on Pain, Bladder-Bowel Function and Sexual Life
The aim of this study to investigate the effect of preoperative pain hypervigilance on postoperative pain, bladder-bowel symptoms and sexual life after vaginal surgery and to compare these parameters before and after surgery.
- Trial name
- NCT07065188
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people
- Sponsor
- Ordu University