Clinical trials: Vaginal Surgery
Vaginal Surgery
Postoperative Belladonna and Morphine Suppositories in Vaginal Surgery
Our primary aim is to determine whether the routine use of belladonna and morphine suppositories will improve pain control following vaginal surgery.
- Trial name
- NCT01150474
- Testing
- Belladonna and Opium Suppositories
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Kristina A. Butler
Sacrospinofixation, Apical Prolapse
Concordance of Pelvic Organ Mobility Measurements Between the Finite Element Model and the Dynamic Pelvic Floor MRI in Patients Undergoing a Sacrospinofixation Surgery
The primary objective of this study is to demonstrate the feasibility of using a Finite Element model of pelvic organs by evaluating the concordance of pelvic organ mobility measurements performed by this mechanical model…
- Trial name
- BiomécaRichter (NCT04551859)
- Testing
- Dynamic Pelvic Floor MRI
- Volunteers
- 41 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Postoperative Pain
Use of Cyclobenzaprine After Vaginal Surgery
The management of post-operative pain in patients after vaginal surgery provides many unforeseen challenges. Although vaginal surgery is considered a minimally invasive approach for the repair of pelvic floor prolapse and urinary…
- Trial name
- NCT01081990
- Testing
- cyclobenzaprine
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Urinary Incontinence, Stress
Complications of Mesh Procedures for Stress Urinary Incontinence
Complications from mesh procedures (i.e. insertion of tension-free vaginal tapes (TVT), trans-obturator tapes (TOT) and suprapubic slings (SS)) used during surgical treatment of stress urinary incontinence have caused major…
- Trial name
- SUI-mesh (NCT02850120)
- Testing
- Tension-free vaginal tape (TVT), Trans-obturator tape (TOT), Suprapubic sling (SS)
- Volunteers
- 101,081 people
- Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
Surgery, Knowledge, Attitudes, Practice
What is the Impact of the Presence of a Support Person on Informed Consent
In practice, the Investigators recommend that patients bring a family member or close friend to their pre-operative appointment to help with patient anxiety, comprehension, and informed decision-making.
- Conditions
- Surgery, Knowledge, Attitudes, Practice, Prolapse, Vaginal, Urinary Incontinence
- Trial name
- NCT03966469
- Testing
- Preoperative support person present, Patient Present Only
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Hartford Hospital
Resident Surgical Training
Video Feedback Versus Verbal Feedback
The long term goal of our research is to develop a curriculum for Obstetrics and Gynecology resident physicians that regularly employs use of video assessment to improve surgical skills.
- Trial name
- NCT02948595
- Testing
- Video feedback followed by structured verbal feedback, Structured verbal feedback followed by video feedback
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Pelvic Organ Prolapse
Comparison of Vaginal Axis on MRI in Alternative Apical Prolapse Surgeries to Sacrocolpopexy
Sacrocolpopexy remains the preeminent modality in addressing apical prolapse surgically. Nevertheless, amplified morbidity rates within cohorts characterized by obesity and advanced age constrain the advantages conferred by the…
- Trial name
- NCT06072456
- Testing
- laparoscopic lateral suspension, laparoscopic pectopexy, Sacrospinous ligament fixation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Pelvic Organ Prolapse
Randomized,Multicentric Study to Treat Prolapse After Hysterectomy With Amreich Procedure or Total Prolift Procedure
Head to Head comparison of perioperative complications and secondary the impact of operation techniques with or without mesh on patients suffering from pelvic organ prolapse on quality of life.
- Trial name
- NCT00572702
- Testing
- Vaginal fixation Amreich-Richter, Prolift total
- Where
- 5 sites in Czechia
- Volunteers
- 200 people
- Sponsor
- Charles University, Czech Republic
Pain
Determination of Analgesic Effect From One Transcranial Magnetic Stimulation(TMS)Treatment Following Vaginal Reconstructive Surgery.
To determine whether real TMS is more effective than sham TMS in reducing pain following surgery
- Trial name
- TMS (NCT02521480)
- Testing
- Active Transcranial Magnetic Stimulation
- Where
- United States
- Sponsor
- East Tennessee State University
Surgery
Objective Structured Assessment of Technical Skills (OSATS) Evaluation of Delivery by Vacuum Extraction
In a prospective, randomized Trial, the investigators compare Hands-on teaching and frontal teaching using a Training Video for learning how to perform an assisted delivery by vacuum extraction on a pelvic Training model.
- Trial name
- VAC-OSATS (NCT02468427)
- Testing
- hands-on teaching, Frontal teaching
- Where
- Germany
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Ruhr University of Bochum
Pelvic Organ Prolapse
A Surgical Simulation Study to Evaluate the Safety of a Device Mechanism as Treatment for Vaginal Apical Prolapse
The purpose of this pilot study is to perform a procedure to evaluate the safety of the placement of a new device (known as the VFIX device).
- Trial name
- NCT00965952
- Where
- 4 sites in Australia
- Volunteers
- 49 people
- Sponsor
- Ethicon, Inc.
Prolapse, Vaginal
Transperineal Ultrasound Evaluation of Vesicourethral Angle and de Novo SUI After Colpocleisis Surgery
This prospective observational study aims to evaluate changes in the vesicourethral angle using transperineal ultrasound before and after colpocleisis surgery, and to assess the relationship of these changes with the development…
- Trial name
- colpocleisis (NCT07071818)
- Testing
- Colpocleisis Group
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Vaginal Delivery, Surgical Site Infection
Skip Prep of Vaginal Delivery to Prevent Puerperal / Perinatal Infection in Vaginal Delivery
This is a multi-center, randomized, controlled trial study to find whether use of chlorhexidine-alcohol or povidone-iodine for pre-vaginal delivery skin prep is superior to reduce postpartum infection in pregnant women with…
- Trial name
- NCT05122169
- Testing
- Povidone-Iodine, Chlorhexidine
- Volunteers
- 4,140 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Hysterectomy, Surgery
Vaginal Cuff Closure by Modification of the Bakay Technique in Total Laparoscopic Hysterectomy
Modified Bakay technique offers a novel colpotomy and cuff closure technique for total laparoscopic hysterectomy (TLH), and consists of placing a single continuous running purse-string suture facilitating the cuff closure before…
- Conditions
- Hysterectomy, Surgery, Laparoscopy
- Trial name
- NCT05080114
- Testing
- Modified Bakay technique (MT), Standard technique (ST)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 148 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Pelvic Organ Prolapse, Pelvic Organ Prolapse (POP)
Accelerometer Measured Early Recovery After Prolapse Surgery
The AccelERate study will evaluate the physical recovery of patients who have undergone Pelvic Organ Prolapse (POP) surgery. This will be evaluated via a self-reported recovery questionnaire completed daily.
- Conditions
- Pelvic Organ Prolapse, Pelvic Organ Prolapse (POP), Pelvic Organ Prolapse Vaginal Surgery, Pelvic Organ Prolapse, Patient Education
- Trial name
- AccelERate (NCT07218016)
- Testing
- Postoperative Exercise regimen
- Where
- 7 sites in United States
- Volunteers
- 288 people
- Sponsor
- NICHD Pelvic Floor Disorders Network
Nerve Block, Pain, Postoperative
Pudendal Nerve Block in Vaginal Surgery
The objective of this this randomized controlled study is to determine whether a pudendal nerve block at the time of vaginal surgery is associated with improved postoperative pain control and decrease opioid consumption compared…
- Conditions
- Nerve Block, Pain, Postoperative, Pelvic Floor Disorders, Pelvic Organ Prolapse
- Trial name
- NCT04198714
- Testing
- Pudendal block
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Gynecologic Surgery
TUbal LIgation Per Differents Endoscopic Routes and Sexuality (TULIPES)
The goal of this clinical trial is compare the quality of sexual life at 6 months after tubal ligation, depending on whether it was performed by abdominal laparoscopy or by vNOTES, on the basis of a non-inferiority hypothesis.
- Trial name
- TULIPES (NCT05910385)
- Testing
- laparoscopy, vnotes
- Where
- 2 sites in France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Clermont-Ferrand
Pain, Postoperative
Preemptive Local Anesthesia in Vaginal Surgery
Preemptive analgesia is an intervention which provides an anesthetic prior to initiating a painful stimulus. This trial is examining the effects of a local anesthetic given at the point of innervation prior to performing a…
- Trial name
- NCT00318292
- Testing
- bupivacaine and epinephrine
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Mayo Clinic
Pelvic Organ Prolapse
SIS Graft and Traditional Repair in Vaginal Wall Prolapse
The objective of this study is to evaluate surgical treatment of anterior vaginal wall prolapse using the sis graft or traditional repair. This a randomized and prospective study.
- Trial name
- NCT00827528
- Testing
- Traditional correction of anterior vaginal wall prolapse, Biologic Graft (SIS)
- Where
- Brazil
- Volunteers
- 56 people
- Sponsor
- Federal University of São Paulo
Dural Puncture Epidural Technique
Dural Puncture Epidural Technique Versus Conventional Epidural Technique During Vaginal Surgeries
The study aims to evaluate whether the dural puncture epidural technique (group B) improves sacral block anesthesia during vaginal surgeries compared with the conventional epidural technique (group A).
- Trial name
- NCT04921761
- Testing
- Conventional epidural, Dural puncture epidural
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt