Clinical trials: Vaginal Surgery
Pelvic Organ Prolapse
A Multi-center Registry Study: The Follow-up the Complications for Trans-vaginal Mesh Surgery
This is a multi-center, prospective, observational, hospital-based registry of pelvic organ prolapse(POP) patients who having trans-vaginal mesh implantation with 12 month and 36 month follow-up.To investigate the incidence of…
- Trial name
- NCT04025047
- Where
- China
- Volunteers
- 4,147 people
- Sponsor
- Peking Union Medical College Hospital
Pelvic Cancer, Anal Cancer
Assessment of Sexual Quality of Life Following Local Treatment (Radiotherapy With or Without Surgery) in Patients With HPV-positive Pelvic Cancer: a Descriptive Longitudinal Study
In patients with cancer associated with human papillomavirus (HPV), the physical effects of treatment, combined with the psychosexual impact linked to HPV status, can further impair the quality of sexual life.
- Conditions
- Pelvic Cancer, Anal Cancer, Vaginal Cancer
- Trial name
- SAPPHIRE (NCT07523152)
- Testing
- Assessment of sexual quality of life
- Volunteers
- 42 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Urinary Retention, Pelvic Organ Prolapse
Urinary Retention After Removing Urinary Catheter at 24 Hour Versus 48 Hour in Patients With Vaginal Surgery
Comparison incident of urinary retention in patients with vaginal surgery of pelvic organ prolapse, who removed urinary catheter at 24 hours versus 48 hours after surgery
- Trial name
- NCT04954443
- Testing
- Removing urinary catheter
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Pelvic Organ Prolapse, PONV
Effects of Preoperative Dexamethasone Study on QOL After Vaginal Reconstructive Surgery for POP
The investigators hypothesize that preoperative administration of 8 mg IV dexamethasone will benefit patients' perceived quality of recovery after surgery.
- Trial name
- NCT02073734
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- TriHealth Inc.
Urinary Stress Incontinence
Transvaginal Tension Free Vaginal Tape-Obturator (TVT-O) Versus Transobturator Tape-Mentor (TOT) in the Management of Urodynamic Stress Urinary Incontinence
Urinary incontinence (involuntary leakage of urine) is an extremely common, distressing and socially disabling condition. It is known to affect up to 14 % of the adult female population in the United Kingdom.
- Trial name
- NCT00136071
- Testing
- Transobturator tape-ARIS, TVT-O
- Where
- United Kingdom
- Volunteers
- 230 people
- Sponsor
- South Glasgow University Hospitals NHS Trust
Quality of Life, Pelvic Floor Distress and Impact Scores
Physical Therapy on Quality of Life and Function Following Vaginal Surgery Reconstructive Surgery
i) The primary objective of this study is to determine if physical therapy improves postoperative quality of life in participants following vaginal reconstructive surgery for pelvic organ prolapse and urinary incontinence.
- Conditions
- Quality of Life, Pelvic Floor Distress and Impact Scores, Sexual Function Scores
- Trial name
- PT and QOL (NCT01403701)
- Testing
- Physical therapy
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Pelvic Organ Prolapse
Vaginal Axis on Magnetic Resonance Imaging After Laparoscopic Pectopexy Surgery: a Controlled Study
Pelvic organ prolapse (POP) is a major public health concern that adversely affects the physical and psychological well-being of women.
- Trial name
- NCT05876975
- Testing
- laparoscopic pectopexy
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Pelvic Organ Prolapse
Vaginal Orthosis Use After Vaginal Reconstructive Surgery
A novel vaginal orthosis, or splint, made of silicone will be used daily to help support the healing vaginal reconstruction during the post-operative phase from week 2 to week 12.
- Trial name
- NOVa (NCT05812859)
- Testing
- Vaginal Orthosis (COSM Medical)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Pelvic Organ Prolapse
The Extended Operations And Pelvic Muscle Training In The Management Of Apical Support Loss Study
Women will be invited to participate in E-OPTIMAL at their last clinical follow-up visit for OPTIMAL (at 24 months post surgery).
- Trial name
- E-OPTIMAL (NCT01166373)
- Testing
- Enrollment video, SSLF, ULS
- Where
- 7 sites in United States
- Volunteers
- 285 people
- Sponsor
- NICHD Pelvic Floor Disorders Network
Cervical Cancers, Vaginal Cancers
Minimally Invasive Pelvic Exenteration in Vaginal or Cervical Cancer Recurrence
The aim of this clinical trial is to assess the oncologic safety of minimally invasive pelvic exenteration in patients with recurrence or persistence of cervical or vaginal cancer with pelvic location, suitable for pelvic…
- Trial name
- MIPEX (NCT06867445)
- Testing
- Minimally invasive pelvic exenteration
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Stress Urinary Incontinence
Reducing Early Urinary Disorders After Stress Incontinence Surgery: The Role of Vaginal Wall Tension.
The progress in surgical procedures for treating female stress urinary incontinence has led to the development of tension-free techniques such as the trans-obturator tape (TOT).
- Trial name
- NCT06292702
- Testing
- Traditional Burch colposuspension, Modified Burch colposuspension
- Where
- Syria
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Damascus University
Pelvic Organ Prolapse, Abnormal Uterine Bleeding
Evaluating Artisential Laparoscopic Instruments in Gynecologic Surgery
This study evaluates the efficacy and safety of Artisential laparoscopic instruments in minimally invasive gynecologic surgery.
- Conditions
- Pelvic Organ Prolapse, Abnormal Uterine Bleeding, Mesh Augmentation, Laparoscopic Surgery
- Trial name
- MIGS-ART (NCT06050161)
- Testing
- Articulating laparoscopic instrument, Conventional laparoscopic instrument, Robotic surgical instrument
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kern Medical Center
Abdominal Hysterectomy
The Application of Vaginal Manipulator in Abdominal Hysterectomy Operations
If a vaginal manipulator is used for abdominal hysterectomy, the vagina can be cut and separated from the cervix without cutting the Cardinal and Sacrouterine ligaments and protecting the top of the vaginal tissue (Portio…
- Trial name
- NCT05420662
- Testing
- Manipulation of vagina during abdominal hysterectomy operation, Classical conventional abdominal hysterectomy operation
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people
- Sponsor
- Kocaeli University
Educational Problems
Comparing Proficiency of Laparoscopic Vaginal Cuff Suturing After Laparoscopic Training in Surgically Naive Students
Surgically naive premedical and medical students were trained on two different laparoscopic simulation trainers, then tested on the same vaginal cuff suturing model.
- Trial name
- NCT04524988
- Testing
- Laparoscopic Simulation Training
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Northwestern University
Quality of Recovery, Same Day Surgery
Dexamethasone Administration To Improve Patient Recovery In Ambulatory Vaginal Prolapse Surgery: Is There A Role?
To the investigators knowledge there are no studies in the literature evaluating the effect of Dexamethasone administration on patients undergoing outpatient vaginal prolapse surgeries.
- Conditions
- Quality of Recovery, Same Day Surgery, Nausea and Vomiting, Postoperative, Vaginal Prolapse
- Trial name
- NCT03338400
- Testing
- Dexamethasone, Normal saline
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- The Cleveland Clinic
Vaginal Vault Prolapse, Pelvic Floor Prolapse
Vaginal Vault Prolapse Surgical Treatment
Since apical support is the mainstay of vaginal cuff restoration, sacrocolpopexy is still accepted as the gold standard technique in vaginal vault prolapse (VVP).
- Trial name
- VVPST (NCT06792331)
- Testing
- vNOTES high uterosacral ligament suspension, Laparoscopic lateral suspension
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Stress Urinary Incontinence
Trans-Obturator Tape Versus Trans-Vaginal Tape for Stress Urinary Incontinence in Women
Stress urinary incontinence (SUI) is a health concern for many women. The transvaginal tape (TVT) surgery has become a common procedure to address the problem. Another surgery is now available, trans-obturator tape (TOT).
- Trial name
- NCT00234754
- Testing
- TVT Surgery TOT Surgery
- Where
- Canada
- Volunteers
- 199 people
- Sponsor
- University of Calgary
Pelvic Organ Prolapse (POP)
Operations and Pelvic Muscle Training in the Management of Apical Support Loss: The OPTIMAL Trial
Pelvic organ prolapse is common among women with a prevalence that has been estimated to be as high as 30%. Pelvic organ prolapse often involves a combination of support defects involving the anterior, posterior and/or apical…
- Trial name
- OPTIMAL (NCT00597935)
- Testing
- SSLF, ULS, PMT
- Where
- 9 sites in United States
- Volunteers
- 374 people
- Sponsor
- NICHD Pelvic Floor Disorders Network
Vaginal Prolapse
Observational Data Collection of Surgical Outcomes in the Treatment of Vaginal Prolapse With AMS Products
This registry was observational (only collected information typically noted by the surgeon when their patients were routinely seen); there was no change to the care the patient received as a result of being part of the registry).
- Trial name
- POWER1012 (NCT00388947)
- Testing
- AMS Prolapse Product
- Where
- United States
- Volunteers
- 1,543 people
- Sponsor
- ASTORA Women's Health
Gender Identity Disorder of Adult, Voiding Disorders
Transgender Post-reassignment Urogynecologic Measures and Perceptions
The intent of this mixed methods study for transgender women after gender confirmation surgery is to characterize and subsequently create a validated screening questionnaire for postoperative urologic and pelvic floor symptoms.
- Conditions
- Gender Identity Disorder of Adult, Voiding Disorders, Sexual Dysfunction
- Trial name
- NCT03293771
- Testing
- Focus group interviews, Questionnaire packet
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University