Clinical trials: Vaginal pH
Bacterial Vaginosis
Effect of Flourish HEC Vaginal Care System on BV Recurrence and the Vaginal Microbiome
The goal of this clinical trial is to learn about the vaginal microbiome in premenopausal women with recurrent bacterial vaginosis (BV).
- Trial name
- NCT05701722
- Testing
- Flourish HEC Vaginal Care System
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Vaginal Biome Science
Vaginal Odor
Safety Assessment of pH-D New Instant Rinse for One Time Use
Demonstrate the safety characteristics of new formulations of pH-D foam wash and instant rinse
- Trial name
- NCT07802483
- Testing
- Lactic Acid instant odor rinse, Boric Acid instant odor rinse
- Volunteers
- 90 people
- Sponsor
- pH-D Feminine Health LLC
Vaginal Atrophy
Evaluate the Efficacy, Safety and Tolerability of a Non-hormonal Intravaginal Gel in Postmenopausal Women With Symptoms of Vaginal Dryness.
Primary: Evaluation of improved vaginal moisture in postmenopausal women. Secondary: the improvement of symptoms resulting from the dryness Rating (VHI), evaluation of the decrease in vaginal pH, assessment of Sexual Function…
- Trial name
- NCT02571127
- Testing
- Hidra1
- Volunteers
- 46 people
- Sponsor
- Farmoquimica S.A.
Vaginal Flora Imbalance
Stryphnodendron Adstringens Intimate Soap
This is a single-centre, single-blind, non-comparative clinical trial to assess the safety of the investigational product through clinical probability assessment.
- Trial name
- NCT06085898
- Testing
- Stryphnodendron Adstringens 3% - once daily post bath
- Where
- Brazil
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Biolab Sanus Farmaceutica
Vaginosis, Bacterial, Vaginal Flora Imbalance
Vaginal Ovule With Flavonoid Tea Extract for the Correction of Imbalance in the Vaginal Environment
Randomized, blinded vehicle-controlled multicenter clinical trial (MAT072017) to determine the effect of vaginal ovules containing 2 mg of the tea extract Matuzalem on the subjective symptoms (5-point scale pruritus (itching)…
- Trial name
- MAT072017 (NCT04171947)
- Testing
- Matuzalem ovule, Vehicle ovule
- Where
- 14 sites in Czechia
- Volunteers
- 274 people
- Sponsor
- Value Outcomes Ltd.
MISED ABORTION- Vaginal PH
Effect of Vaginal PH on Treatment Effectiveness With Misoprostol for First Trimester Missed Abortions
vaginal PH has an effect on the effectiveness of treatment with misoprostol given vaginally for missed abortions in the first trimester
- Trial name
- NCT01270334
- Testing
- PH meassurment
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Vaginal Microbiota, Microbiota
Effect of Hifas Intima Oral on Vaginal Microbiota in Healthy Women
The goal of this clinical trial was to learn whether the vaginal microbiota changed after healthy women aged 18 to 45 years took Hifas Intima, an oral food supplement, for 3 months.
- Conditions
- Vaginal Microbiota, Microbiota, Vaginal Microbiome
- Trial name
- NCT07715058
- Testing
- Hifas INTIMA Oral
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hifas da Terra S.L.
Vaginitis, Bacterial Vaginosis
Real-world Performance and Safety of Cerviron® in the Treatment of Vaginitis
Vaginitis is a broad term that includes a range of gynecological disorders characterized by infection of vaginal mucosa, inflammation of vulva and alteration of the normal vaginal microflora.
- Trial name
- NCT05652959
- Testing
- Cerviron®
- Where
- 10 sites in Romania
- Volunteers
- 111 people
- Sponsor
- Perfect Care Distribution
Pregnancy, Bacterial Vaginosis
Bacterial Vaginosis in Pregnancy: Detection by Weekly Vaginal pH Testing
Interventional study to assess the effect of early detection and treatment of bacterial vaginosis in pregnancy on preterm delivery rate.
- Conditions
- Pregnancy, Bacterial Vaginosis, Preterm Delivery
- Trial name
- NCT00799500
- Testing
- Screening
- Where
- Spain
- Volunteers
- 1,049 people, healthy volunteers welcome
- Sponsor
- Montse Palacio
Bacterial Vaginosis
Flourish HEC to Prevent Recurrence of BV
In a population of women with heightened vulvovaginal sensitivity and recurrent bacterial vaginosis (BV), the use of the Flourish HEC Vaginal Care System is being tested for prevention of BV recurrence over six months of use.
- Trial name
- NCT05386147
- Testing
- Flourish HEC Vaginal Care System (contains a class II medical device plus other unregulated components)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Vaginal Biome Science
Vaginosis, Vaginosis, Bacterial
Postmenopausal Pessary Users: Estrogen Versus Trimosan
The purpose of the study is to compare vaginally applied estrogen with the vaginal gel trimosan for their effects on vaginal pH and vaginal symptoms in postmenopausal pessary users.
- Conditions
- Vaginosis, Vaginosis, Bacterial, Vaginal Discharge
- Trial name
- NCT03943823
- Testing
- Estrogen vaginal cream, Trimo-San vaginal gel
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- The University of Texas Health Science Center, Houston
Vaginal Infection
Performance Proof of Product Developed to Detect Abnormal Vaginal pH
This study was designed to validate the color appearance on the NORMA-SENSE gen 3 when comes into contact with vaginal secretions having an elevated pH level
- Trial name
- NCT01542606
- Testing
- NORMA-SENSE
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Common Sense
Labor, Induced, Induced; Birth
Effect of Acidic Vaginal pH on the Efficacy of Dinoprostone for Labor Induction
Acidification of vaginal pH has been proposed as a potential factor that could help increase the efficacy of vaginal prostaglandins in labor induction.
- Trial name
- NCT05100264
- Testing
- Vaginal washing with 5% acetic acid, Vaginal washing with 0.9% NS
- Where
- Greece
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Alexandra Hospital, Athens, Greece
Vaginal Infection
Performance Proof of the New NORMA-SENSE
This study was designed to validate the color appearance on the newly developed panty liner (NORMA-SENSE). The NORMA-SENSE liner changes color when worn by the user and comes into contact with vaginal secretion with an elevated…
- Trial name
- NCT00802763
- Testing
- NORMA-SENSE
- Where
- Israel
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Bacterial Infections, Treatment of Fungal Infections, Candidiasis
Prospective Clinical Study, Using a Medical Device (RepHegyn) as an Adjuvant in the Treatment of Fungal (Candidiasis) and Bacterial Infections
The medical device It is indicated to promote the re-epithelialization processes of the vaginal mucosa, in the prevention of vaginal conditions of bacterial and fungal origin, and as an adjuvant in their treatment.
- Trial name
- NCT07367295
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- Innate srl
Vaginitis and Vulvovaginitis
Clinical Investigation To Evaluate Cerviron Ovules® in Symptomatic Vaginitis
CYRON is a Prospective, Open-Label, Pilot, Multicentric Clinical Investigation to Evaluate the Performance and Safety of Cerviron Ovules® in the Local Treatment of Non-Specific or Endogenous, Symptomatic Vaginitis.
- Trial name
- NCT04735705
- Testing
- Cerviron
- Where
- 2 sites in Romania
- Volunteers
- 50 people
- Sponsor
- Perfect Care Distribution
Menopause, Hormone Replacement Therapy
Menopausal Vaginal Microbiome
In this study the investigators will analyze the vaginal microbiome of menopausal women in order to shed light on its potential implication on menopausal symptoms and quality of life.
- Conditions
- Menopause, Hormone Replacement Therapy, Genitourinary Syndrome of Menopause
- Trial name
- NCT05122065
- Volunteers
- 432 people, healthy volunteers welcome
- Sponsor
- FemTec Health Inc.
Vaginal Health, Bacterial Vaginosis
A Single Group Study to Evaluate the Effects of a Boric Acid Suppository on Vaginal Health.
This is a virtual single-group clinical trial that will last 12 weeks. Participants will use The Killer® (Boric Acid Suppositories) once daily for 7 consecutive days when they feel that they are experiencing any of the common…
- Trial name
- NCT06516757
- Testing
- Boric Acid Suppository
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Love Wellness
Vaginal Infection
Feasibility Study of the NEW NORMA-SENSE
In-vitro study Collect data regarding the color appearance on the new developed indicator strips (NEW NORMA-SENSE), in contact with vaginal secretion with elevated pH Measure the buffering capacity of vaginal secretion from…
- Trial name
- NCT00324246
- Where
- Israel
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Vaginal Microbiome
Longitudinal Analysis of the Vaginal Microbiome
This is a longitudinal, observational study with the goal of understanding vaginal microbiome changes both within a single day and across a menstrual cycle.
- Trial name
- NCT05383326
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Viome