Clinical trials: Validation Studies
Speech Intelligibility, Aging
Speech Perception With High Cognitive Demand
With advancing age, adults experience increasing speech understanding difficulties in challenging situations. Currently, speech-in-noise difficulties are rehabilitated by providing hearing aids.
- Trial name
- NCT04698356
- Testing
- Auditory-cognitive training paradigm
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Clinical Competence, Health Communication
Validation of the Healthcare Relationship Assessment Scale (ERA) in Health Sciences Students.
This study aims to design and psychometrically validate a practical and agile observational instrument-the Healthcare Relationship Assessment scale (ERA scale)-to evaluate communication skills and person-centered care among…
- Conditions
- Clinical Competence, Health Communication, Professional-Patient Relations, Patient-Centered Care
- Trial name
- COPS-ERA (NCT07911241)
- Testing
- ERA Scale (Healthcare Relationship Assessment Scale)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universidad Loyola Andalucia
BCL2 Gene mRNA Overexpression
Validation of Useful Markers Generated by Next Generation Bio-data Based Genome Research and Cohort Study
Multiple biomarker development through validation of useful markers generated by next generation bio-data based genome research and cohort study
- Trial name
- miRNA_Chip (NCT02807896)
- Where
- South Korea
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- CHANGHEE LEE
Overactive Bladder
Turkish USIQ: Validity & Reliability
The Urgency, Severity, and Impact Questionnaire (USIQ) assesses urinary urgency independently of incontinence, measuring both symptom severity and its impact on quality of life.
- Trial name
- NCT07452796
- Testing
- Observational Cohort
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
PTSD - Post Traumatic Stress Disorder, PTSD-Related Functional Impairment in Children and Adolescents
Development of the PTSD-iMPACT to Measure PTSD-Related Functional Impairment in Children and Adolescents - A Validation Study in Switzerland and Germany
Population-based and clinical studies indicate that a substantial proportion of children and adolescents are exposed to one or more potentially traumatic events (PTEs) Approximately 16 % of those affected by childhood trauma go…
- Trial name
- PTSD-iMPACT (NCT07368166)
- Where
- 11 sites in Germany, Switzerland
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Omphalitis
Omphalitis Community Based Algorithm Validation Study
The objective of this study is to develop and test a simple community-based diagnostic algorithm for omphalitis in sub-Saharan Africa.
- Trial name
- OCAVS (NCT01687621)
- Testing
- Diagnostic Algorithm for Community Based Worker for Omphalitis
- Where
- Zambia
- Volunteers
- 1,009 people, healthy volunteers welcome
- Sponsor
- Boston University
Muscle Strength, Muscle Weakness
Reliability and Validation of New Manual Dynamometer to Measure Lower Limb Strength
INTRODUCTION: There are several ways to assess muscle strength: not only subjective ways, but also high standard equipment, such as isokinetic dynamometers. These, however, are expensive, and require extensive training.
- Trial name
- NCT05573139
- Testing
- Assessment of muscle strength by manual dynamometry
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Cancer
Development and Validation of a Health-related Quality of Life Instrument
This study aims to develop a health related quality of life (HRQOL) patient reported outcome (PRO) for patients receiving immune checkpoint modulator (ICM) therapy.
- Trial name
- FACT-ICM (NCT02651831)
- Testing
- Focus groups and individual interviews, Questionnaire
- Where
- Canada
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Sepsis, Sepsis Bacterial
A Validation Study of the Lab Clasp Device: A Point of Care Sepsis Risk Monitor
The overall purpose of this study is to demonstrate the usability of a clinical-grade device in the form of a finger clasp similar to a pulse oximeter for monitoring lactate values, by comparing its performance in reading…
- Conditions
- Sepsis, Sepsis Bacterial, Lactate Blood Increase, Infectious Disease
- Trial name
- NCT04796285
- Testing
- Lab Clasp
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Manual Dexterity
Validation and Test-retest Study of the Star-shaped Manual Dexterity Test.
The purpose of this study is to measure test-retest reliability and validate the star shaped test of manual dexterity. The purpose of this is to see if there is any significant learning effect, and if the test can discriminate…
- Trial name
- NCT02146443
- Testing
- Stretched arm test, Stress, Star shaped manual dexterity test
- Where
- Denmark
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Nasal Valve Collapse
Validity Study of a Nasal Valve Implant
The purpose of this study is to determine if an implant material can be injected to repair nasal valve collapse.
- Trial name
- NCT00837525
- Testing
- nasal valve implant
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Nasoform, LLC
Mitochondrial Oxygenation Measurement, Measurement Error
Mitochondrial Oxygen Measurement Variability in Critically Ill Patients (INOX Variability Study)
To determine the between- and within-subject variability of the mitochondrial oxygenation measurement with the COMET device over time in healthy subjects and in hemodynamically stable subjects admitted to the intensive care unit.
- Conditions
- Mitochondrial Oxygenation Measurement, Measurement Error, Healthy
- Trial name
- NCT04626661
- Testing
- COMET measurement system
- Where
- Netherlands
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Sanquin-LUMC J.J van Rood Center for Clinical Transfusion Research
Atrial Fibrillation (AF), Paroxysmal Atrial Fibrillation (PAF)
Multi-Centre Based Study Recognition of Atrial Fibrillation With the Corsano CardioWatch 287-2 System
This concerns a multi-center, single-arm, diagnostic accuracy study. In this study, a wristband that monitors heart rythm is assessed in clinical and free living conditions.
- Trial name
- COR-AF (NCT06955273)
- Testing
- Corsano CardioWatch 287-2
- Where
- Netherlands
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Corsano Health B.V.
Contracture, Joint Contracture
Development, Validation and Evaluation of the Feasibility of the Observational Risk Assessment of Contractures (Longitudinal Evaluation) Tool: The ORACLE Study
The Observational Risk Assessment for Contractures- Longitudinal Evaluation (ORACLE) is a risk assessment tool for contractures.
- Trial name
- NCT06042907
- Where
- 8 sites in United Kingdom
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Bournemouth University
Motor Activity
Validating Accelerometers to Study Physical Activity of Toddlers
One way to assess impacts of nutrition supplements to health is to measure physical activity. Physical activity can be measured with small devices called "accelerometers".
- Trial name
- NCT01188044
- Where
- Malawi
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Tampere University
Allergy, Allergic Asthma
abioSCOPE IgE Assay to Aid in the Diagnosis of Allergies
This is a multicenter, prospective, observational study designed to determine the clinical sensitivity and specificity of the Abionic IVD CAPSULE Allergic Asthma panel performed on Abionic's abioSCOPE device using K3-EDTA…
- Conditions
- Allergy, Allergic Asthma, Allergy to Cats, Allergy to House Dust
- Trial name
- NCT04442932
- Testing
- Blood Collection
- Where
- 5 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Abionic SA
Borderline Personality Disorder
Screening of the Possible Risk Factors for Borderline Personality Disorders and Validation of Maclean Instrument
Borderline personality disorder is a mental illness that severely impacts a person's ability to regulate their emotions. This loss of emotional control can increase impulsivity, affect how a person feels about themselves, and…
- Trial name
- NCT05831852
- Testing
- no intervention
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Renal Insufficiency, Chronic, Heart Failure
Clinical Validation Through Analytical Study With Urine Samples to Compare the Effectiveness and Security of an Intelligent Device
The objectives of the Clinical Validation Through Analytical Study With Urine Samples to Compare the Effectiveness and Security of an Intelligent Device are: 1.To evaluate the performance of S-There Device in comparison to the…
- Conditions
- Renal Insufficiency, Chronic, Heart Failure, Diabete Mellitus, Diabetes; Nephropathy (Manifestation)
- Trial name
- STSD-2019-001 (NCT03965975)
- Testing
- Lab Gold Standard, S-There
- Where
- Spain
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- S-There Technologies SL
Performance and Safety
Clinical Study of CT 5400 RT for System Validation
The purpose of this clinical trial is to evaluate the efficacy and safety of the CT 5400 RT System.
- Trial name
- NCT06466577
- Testing
- CT 5400 RT System
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Chronic Headache
The Turkish Fear of Pain Questionnaire
Children's chronic pain is a significant condition that affects roughly 25% of children, with approximately 3% of them requiring intense pain therapy.
- Trial name
- NCT05414513
- Where
- Turkey (Türkiye)
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Akdeniz University