Clinical trials: Validity, open to volunteers
Inherited Metabolic Disorders
AI for Newborn Metabolic Screening
The goal of this clinical trial is to evaluate whether an artificial intelligence (AI)-based interpretation system can accurately diagnose inherited metabolic disorders in newborns undergoing routine screening.
- Trial name
- NCT07368504
- Testing
- Artificial intelligence-based interpretation system for newborn genetic metabolic disease screening
- Where
- China
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Breast Cancer, Vascular Calcification
Tissue Validation of Mammographic Breast Arterial Calcification in Mastectomy Specimens
Breast arterial calcification (BAC) is a common incidental finding on screening mammograms and has been associated with cardiovascular disease in women. However, every study in this field has been imaging-based.
- Conditions
- Breast Cancer, Vascular Calcification, Coronary Artery Calcification, Atherosclerosis Cardiovascular Disease
- Trial name
- SIDEMARA (NCT07865884)
- Volunteers
- 100 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Trigeminal Neuralgia
Risk Factors for Recurrence of Trigeminal Neuralgia After Percutaneous Balloon Compression
The goal of this observational study is to develop and validate a machine learning-based model for predicting pain recurrence risk after percutaneous balloon compression (PBC) in adult patients with primary trigeminal neuralgia…
- Trial name
- NCT07238244
- Testing
- Percutaneous Balloon Compression
- Volunteers
- 700 people
- Sponsor
- Second Xiangya Hospital of Central South University
Shoulder Pain, Rotator Cuff Related Shoulder Pain
Night Pain Module for Rotator Cuff-Related Shoulder Pain
Night pain is common in people with rotator cuff-related shoulder pain and may disturb sleep and daily life. It may include difficulty falling asleep, waking because of pain, increased pain during the night, difficulty returning…
- Trial name
- NCT07838233
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 275 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Intracranial Hemorrhages
BLANDISH (Brain, Loss of Function, Aneurism, Disease, Injury, Stroke, Hemorrhage)
The goal of this observational study is to train a machine learning system based on data from patients affected by spontaneous Intracranial Hemorrage.
- Trial name
- BLANDISH (NCT06320132)
- Testing
- Treatment of spontaneous intracranial hemorrhage
- Where
- Italy
- Volunteers
- 2,000 people
- Sponsor
- IRCCS Ospedale San Raffaele
Chronic Pain
Turkish Version of a Scale Measuring How People View Chronic Pain
This study will translate and culturally adapt the Patients' Endorsement of a Biopsychosocial Model of Chronic Pain Scale (PEB) into Turkish and evaluate how well and consistently it measures the views of adults with chronic…
- Trial name
- NCT07861698
- Where
- Turkey (Türkiye)
- Volunteers
- 220 people
- Sponsor
- Bilecik Seyh Edebali Universitesi
Merkel Cell Carcinoma of Skin
Validation of in Vitro Method for Anti-MCPyV Immunotherapy on Patients With Cutaneous Merkel Cell Carcinoma
The aim of the study is to test and validate in vitro a cell therapy approach for MCPyV+ Merkel Cell Carcinoma patients.
- Trial name
- VIRASKIN (NCT06780475)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cerebellar Cognitive-affective Syndrome
Validation of the Performance of the French Version of the Cerebellar Cognitive-Affective Syndrome Scale (CCASS) as a Screening Test for Cerebellar Cognitive-affective Syndrome: a National Multicenter Study
The primary objective of the study is to assess the performance of the French version of the Cerebellar Cognitive-Affective Syndrome Scale (CCASS) as a screening test for cerebellar cognitive-affective syndrome.
- Trial name
- CCASS-FR (NCT06005844)
- Testing
- Cerebellar Cognitive-Affective Syndrome Scale
- Where
- France
- Volunteers
- 217 people
- Sponsor
- Groupe Hospitalier de la Region de Mulhouse et Sud Alsace
Cricoid Pressure
Validation of a Novel Handheld Device for Accurate Cricoid Pressure in Healthy Volunteers
Pulmonary aspiration of gastric contents is a leading cause of anesthesia-related morbidity and mortality, particularly in emergency surgeries and among patients who are not appropriately fasted prior to airway intervention.
- Trial name
- NCT06540625
- Testing
- the use of CP device application on human subjects.
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Chronic Kidney Diseases, Protein-Energy Malnutrition
Effect of a Specialized Oral Supplement on Nutritional Status and Quality of Life in Non-dialysis CKD
Patients whit chronic kidney disease (CKD) there is a high prevalence of nutritional disorders and negative changes in body composition, which is strongly associated with an increased risk of morbidity and mortality.
- Trial name
- NCT06576479
- Testing
- Nutritious Shake, Nutritional counseling
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- NIN Institute
Other
Reliabılıty,Validity Of The Turkish Version Of The KNAP
This study, we performed the Turkish version validity and reliability of the KNAP
- Trial name
- NCT06687317
- Testing
- Behavioral
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Gazi University
Postpartum Depression, Postpartum Disorder
Maternal Well-being in the Postnatal Stage
The objective of this study is to design and validate an online intervention aimed at promoting well-being in women with postpartum depression.
- Trial name
- BIEMAT (NCT05676918)
- Testing
- Positive Psychology Intervention, Cognitive Behavior Therapy
- Where
- Spain
- Volunteers
- 98 people
- Sponsor
- Universidad Complutense de Madrid
Validation Fugl-Meyer Scale in Italian
Validation Fugl-Meyer in Italian Language (FMI)
The aim of the study is to perform a cultural validation of the Italian translation of the Fugl-Meyer Assessment scale for the upper and the lower limb on a group of post-stroke patients admitted to the neurological department at…
- Trial name
- NCT04117997
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Healthy Children
Urdu Translation of Revised High-Level Mobility Assessment Tool (HiMAT) in Healthy Children
The ability to move with ease is labelled as mobility. Limitations in mobility are frequent, recovery of these skills is crucial for physical performance which gives children valuable social possibilities and has long-term…
- Trial name
- NCT06986720
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Cervical Cancer, HPV Infection
Hospital-based Validation of the New ELEVATE Screening Tool
ELEVATE is a six-year project, conducted by an international research alliance led by Ghent University, aiming to develop a new test and approach for cervical cancer screening in hard-to-reach populations.
- Trial name
- ELEVATE-Pilot (NCT06304610)
- Testing
- Questionnaire, HPV self-sample, Endocervical sample
- Where
- 2 sites in Belgium, Ecuador
- Volunteers
- 200 people
- Sponsor
- University Hospital, Ghent
Solid Cancer
Study of Radiology Manipulator Work Validation by the Radiologist
The main objective of this study is to evaluate the pre-filling work on target and non-target lesions, and the detection of any new lesions reported by the MEM trained in protocol evaluations, in a structured table to prepare the…
- Trial name
- Cimer (NCT06894082)
- Where
- France
- Volunteers
- 87 people
- Sponsor
- Institut Paoli-Calmettes
Pressure Injuries, Pressure Ulcers, Bedsores, Decubitus Ulcer
Prevention of Pressure Injury (PI) in Hospitalised Infants, Children, and Young People (CYP) (Aged 0-19 Years)
What is the problem? Children and young people admitted to hospital can sometimes be harmed by what is called a pressure injury. Pressure injuries are sores (ulcers) that happen on areas of the skin that are under pressure.
- Trial name
- CYPPI (NCT07303569)
- Where
- United Kingdom
- Volunteers
- 542 people, healthy volunteers welcome
- Sponsor
- Nottingham University Hospitals NHS Trust
Irritation; Anus
Validation of TRansanal Irrigation Adherence scaLe (TRIAL)
Transanal irrigation (TAI) is a method used to empty stools from the recto-sigmoid and colon (from the descending colon to the transverse colon).
- Trial name
- NCT06805903
- Testing
- TRansanal Irrigation Adherence scaLe
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Work-Related Musculoskeletal Disorders, Musculoskeletal Diseases
Development of Multidimensional Screening Tool for WMSDs
The purpose of this study is to develop a multidimensional screening tool for Work-Related Musculoskeletal Disorders (WMSDs) and to evaluate its psychometric properties.
- Conditions
- Work-Related Musculoskeletal Disorders, Musculoskeletal Diseases, Occupational Diseases
- Trial name
- NCT07367646
- Testing
- Survey Administration
- Where
- South Korea
- Volunteers
- 250 people
- Sponsor
- Sahmyook University
Cerebral Palsy, Cerebral Palsy (CP)
Validity Assessment of Sensors for Movement Tracking With Children/Youth With Diverse Neuromotor Abilities
The overall goal of this study is to establish the clinical utility and accuracy of markerless motion captures systems for tracking therapy exercises and movement during game play. Specific aims are: 1.
- Trial name
- MOCAP (NCT07360171)
- Testing
- Validity Assessment of Sensors for Movement Tracking With Children/Youth With Diverse Neuromotor Abilities
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
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