Clinical trials: Validity
Mitochondrial Myopathies, Mitochondrial Diseases
Validation of Oxygen Nanosensor in Mitochondrial Myopathy
Past mitochondrial disease treatment studies have been unsuccessful in determining treatment efficacy, and a major factor has been the lack of validated biomarkers in mitochondrial myopathy (MM).
- Trial name
- NCT04086329
- Testing
- Nanosensor
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Breast Cancer, Screening
Breast Cancer Risk From Sonographic Glandular Tissue Component (or International GTC Study)
An international multicenter study to prospectively validate the association between sonographic GTC and subsequent breast cancer risk in women with dense breasts.
- Trial name
- NCT05460975
- Where
- South Korea
- Volunteers
- 16,164 people
- Sponsor
- Seoul National University Hospital
Frontotemporal Lobar Degeneration
DAPHNE Scale Validation in Frontotemporal Lobar Degeneration
Psycho-behavioral disorders assessment is crucial for the diagnosis and follow-up of patients with frontotemporal degeneration (FTD).
- Trial name
- DAPHNE (NCT02889601)
- Testing
- Psycho-behavioural assessment
- Where
- France
- Volunteers
- 89 people
- Sponsor
- Nantes University Hospital
Gastric Cancer
Pepsinogen II and Helicobacter Pylori Test in Gastric Cancer
The aim of this study to validate the role of pepsinogens in gastric cancer screening.
- Trial name
- NCT06301464
- Where
- South Korea
- Volunteers
- 24,000 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Prostate Adenocarcinoma
Molecular PET/MR Imaging in Vivo Validation of Biomarker for Human Prostate Cancer
Primary objective: To correlate the blood/urine metabolomic biomarkers with PET/MR imaging. Secondary objectives: 1. To evaluate the sensitivity and specificity of the PET/MR in diagnosis of prostate cancer. 2.
- Trial name
- PCAPETMR (NCT03451812)
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Chang Gung Memorial Hospital
Rett Syndrome
Validating Innovative Biosensors for Rett Autonomic Symptom Tracking
The VIBRANT study aims to validate biosensors to objectively and directly measure symptoms in Rett syndrome and create confidence in the use of these devices in clinical trials.
- Trial name
- VIBRANT (NCT06338267)
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Rett Syndrome Research Trust
Ultrasound Imaging of Anatomical Structures
Data Collection for the Validation of an Artificial Intelligence Software to Support Musculoskeletal Ultrasound Examination
This study conducted at three locations, aiming to collect ultrasound images from volunteers and assess the performance of an AI software, MSK Go, using these images.
- Trial name
- NCT07336407
- Testing
- Ultrasound Scans
- Where
- 3 sites in United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Smart Alfa Teknoloji San. ve Tic. A.S.
Weight Management, Cardiovascular (CV) Risk
Feasibility, Acceptability, and Validation of a User-friendly Diet Quality Tool in Adults From Ambulatory Nutrition Clinics
The study design for Perceptions and Learning About a Diet Tool (PLATE) was a prospective online dietary intake survey in adults engaged in ambulatory nutrition counseling.
- Conditions
- Weight Management, Cardiovascular (CV) Risk, Metabolic and Nutritional Disorders
- Trial name
- PLATE (NCT07109011)
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- University of Pennsylvania
Parkinson Disease, Ataxia
Validation of Bulbicam for Parkinson- and Ataxia-patients
Aim is to investigate repeatability and stability of four Neurological-related Bulbicam tests in patients suffering Parkinson (PD),Ataxia (AT) and matched healthy control (HC).
- Trial name
- NCT05680571
- Testing
- BulbiCam
- Where
- Norway
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Meddoc
Acute Cardiovascular Disease
AI-POD Clinical Validation Study for Obese Patients
The study is aimed at patients who suffer from severe obesity and receive a computerised tomography (CT) scan of the heart. A total of 1200 patients across Europe are to take part in the study.
- Trial name
- AI-POD (NCT06595134)
- Testing
- Non Interventional
- Where
- 6 sites in Austria, Belgium and 3 more
- Volunteers
- 1,200 people
- Sponsor
- University Hospital, Bonn
Lung Cancer, Red Blood Cells
The Red Blood Cells Based Blood Test for Lung Cancer EARLY Detection
This study plan to enroll 852 patients with pulmonary nodules smaller than 3 cm in diameter, whose DNA and RNA will be extracted from mature red blood cells isolated from peripheral blood.
- Conditions
- Lung Cancer, Red Blood Cells, Methylation
- Trial name
- NCT05380999
- Testing
- Methylation tests of nucleic acids extracted from mature red blood cells (RBCs)
- Volunteers
- 852 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Oncology
The Internal Prospective Validation of the Cancer Admission Score (CAS) Prediction Model
The goal of this single center prospective observational study is to determine the agreement between the cancer admission score (CAS) predicted disposition and the actual disposition in patients with an active cancer diagnosis…
- Trial name
- ONCOMING (NCT06558487)
- Testing
- Cancer Admission Score Prediction Model
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Erasmus Medical Center
Altered Taste
TQ-PAL Development and Validation
Taste problems are common among patients with advanced cancer. These symptoms can affect the pleasure of eating and drinking, reduce dietary intake, cause low mood, and a lower quality of life.
- Trial name
- NCT06588933
- Testing
- completion of a questionnaire
- Where
- Ireland
- Volunteers
- 200 people
- Sponsor
- Prof Andrew Davies
Trauma
Evaluating the New Trauma Score (NTS) for Improved Mortality Prediction
The goal of this prospective cohort study is to evaluate the predictive accuracy of the New Trauma Score (NTS), a modification of the Revised Trauma Score (RTS), in determining mortality outcomes among trauma patients admitted to…
- Trial name
- NTS (NCT06732752)
- Where
- Iraq
- Volunteers
- 177 people
- Sponsor
- Al-Nahrain University
Acute Appendicitis
Comparative Study on the Diagnostic Validity of the Alvarado Score, Appendicitis Inflammatory Response (AIR), and Adult Appendicitis Score (AAS) in Acute Appendicitis at East Lancashire Hospitals NHS Trust (ELHT)
This retrospective observational study aims to compare the diagnostic accuracy of Alvarado Score, Appendicitis Inflammatory Response (AIR) Score, and Adult Appendicitis Score (AAS) in predicting histologically confirmed acute…
- Trial name
- DV-AAA ELHT (NCT07804238)
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- East Lancashire Hospitals NHS Trust
Hospital Acquired Pneumonia
Validity of Biological Material Sampling in Patients With Hospital-acquired Pneumonia
The main objective of project is to compare validity of sampling methods performed routinely (bronchial secretion, stomach content, oropharyngeal smear) for determination of etiological agent responsible for hospital-acquired…
- Trial name
- NCT03039998
- Volunteers
- 56 people
- Sponsor
- University Hospital Olomouc
Heart Failure
Urdu Translation and Validation of MLHFQ
To translate the Minnesota Living with Heart Failure Questionnaire (MLHFQ) questionnaire into Urdu language of Pakistan. To determine the validity and reliability of cross cultural adapted and Urdu translated MLHFQ questionnaire…
- Trial name
- NCT06076447
- Where
- Pakistan
- Volunteers
- 210 people
- Sponsor
- Riphah International University
Kidney Disease
Designing a Bayesian Model of the Plasma Clearance of Calcium Edetate de Sodium for the Calculation of GFR and Validity Compared to the Renal Clearance of Inulin
Diagnosis of patients with renal insufficiency and recommendations for medical treatment of patients who suffer from chronic renal failure are based on the different stages of Glomerular Filtration Rate (GFR).
- Trial name
- DFGBay (NCT02300376)
- Testing
- Dosage of Calcium edetate de sodium
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Limoges
Musculoskeletal Pain, Questionnaire
The Turkish Version of the Musculoskeletal Pain Intensity and Interference Questionnaire for Musicians (MPIIQM-T)
The aim of this study, original named "The musculoskeletal pain intensity and interference questionnaire (MPIIQM)" is the Turkish validation, reliability and cross-cultural validation of the questionnaire.
- Trial name
- NCT04785040
- Testing
- The groups evaluated by The Musculoskeletal Pain Intensity and Interference Questionnaire for Professional Orchestra Musicians, Brief Pain Inventory, QuickDASH and Fatigue Severity Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Ankara Yildirim Beyazıt University
Adenomyosis
Validation and Optimisation of Ultrasound Diagnosis of Adenomyosis
Defining ultrasound criteria for normal uterine biometry and assessing the prevalence of repeat abortions in patients with abnormalities of the uterine cavity
- Trial name
- NCT06795711
- Where
- Italy
- Volunteers
- 465 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
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