Clinical trials: Validity and Safety
Atopic Eczema/Dermatitis (Non-Specific)
Skin bioMARkers for Atopic Eczema Therapy Evaluation
The study aims to investigate two new non-invasive technologies for assessing skin properties to identify and validate a range of safety biomarkers that may be considered useful as primary outcome measures for evaluating the…
- Trial name
- SMART (NCT04194814)
- Testing
- crisaborole (2%) ointment, betamethasone valerate 0.1% cream
- Where
- United Kingdom
- Volunteers
- 37 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Deglutition Disorders, Deglutition
Translation and Validation of the Visual Analysis of Swallowing Efficiency and Safety Into European Portuguese
The goal of this observational study is to translate and validate to European Portuguese "Visual Analysis of Swallowing Efficiency and Safety - VASES".
- Trial name
- VASES (NCT06742034)
- Where
- Portugal
- Volunteers
- 34 people
- Sponsor
- Centro Hospitalar de Entre o Douro e Vouga
Triple Negative Breast Cancer, Breast Cancer
TA(E)C-GP Versus A(E)C-T for the High Risk TNBC Patients and Validation of the mRNA-lncRNA Signature
The purpose of this study is to compare the efficacy and safety between docetaxel combined with doxorubicin (epirubicin) and cyclophosphamide followed by gemcitabine combined with cisplatin and doxorubicin (epirubicin) combined…
- Trial name
- NCT02641847
- Testing
- docetaxel, doxorubicin or epirubicin, cyclophosphamide
- Where
- China
- Volunteers
- 503 people
- Sponsor
- Fudan University
Coronary Artery Disease, Acute Myocardial Infarction
Heart Cycle Prestudy
In this Prestudy which will be followed by the multicentral GEx- main-trial, the feasibility of a new cardiac rehabilitation device (GEx system) is proved with coronary heart disease patients who participate in cardiac…
- Trial name
- PreGEx (NCT01627457)
- Testing
- Guided Exercise (GEx) system
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- RWTH Aachen University
Stroke, Exercise
Community-based Complex Exercise for Stroke Patients
A lot of physical and social effects of exercise programs and daily physical education have already been proven for stroke patients after discharge.
- Trial name
- COB-CEPS (NCT06012396)
- Testing
- Stoke complex exercise program
- Where
- South Korea
- Volunteers
- 126 people
- Sponsor
- Pusan National University Yangsan Hospital
Quality of Life, Sexual Activity
Quality of Life and Sexual Function of Vaginal Operation in The Treatment Of Previous Cesarean Scar Defect
The aim of this study is to further demonstrate the safety , validity and quality of (sexual)life of vaginal operation for previous cesarean scar defect resection.
- Trial name
- PCSD (NCT01978067)
- Testing
- transvaginal resection of Uterine Scar
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shu-Qin Chen
Idiopathic Pulmonary Fibrosis
Study to Test the Validity of the Treatment of Idiopathic Pulmonary Fibrosis With Cotrimoxazole
First study to test the validity of the treatment of idiopathic pulmonary fibrosis, which causes inflammation and fibrosis (scarring) of the lung tissue, with cotrimoxazole.
- Trial name
- TriSulfa-FPI (NCT01777737)
- Testing
- Cotrimoxazole
- Where
- Spain
- Volunteers
- 3 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Refractive Errors
Study to Evaluate the Reliability, Validity and Safety of Subjective Mobile Refraction
This study evaluates the reliability, validity and safety of a self administered, subjective refraction test via a mobile medical app (GoEyes) as compared to standard of care subjective manifest refraction performed by a health…
- Trial name
- NCT05049070
- Testing
- Mobile medical application to self administer a subjective refraction test, Standard of care refraction test
- Where
- 12 sites in United States
- Volunteers
- 349 people
- Sponsor
- 1800 Contacts, Inc.
Glioma : Oligodendroglioma or Astrocytoma
Multicenter Safety Trial Assessing an Innovative Tumor Molecular and Cellular Print Medical Device in Glioma
The purpose of the study is to determine the clinical safety and operability of the innovative tissue imprint device ProTool.
- Trial name
- ProTool (NCT02077543)
- Testing
- Brain Tissue Imprint - Medical Device (ProTool)
- Where
- 5 sites in France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Grenoble
Niemann-Pick Disease, Type C
Biomarker Validation for Niemann-Pick Disease, Type C: Safety and Efficacy of N-Acetyl Cysteine
Background: Niemann-Pick disease type C (NPC) is a genetic disorder that results in progressive loss of nervous system function by affecting the membranes of nerve cells. There is no known cure for NPC.
- Trial name
- NCT00975689
- Testing
- N-Acetyl Cysteine
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Surgery
Validation of a User Questionnaire to Assess Surgeon Satisfaction and Perspectives on Robotic Surgical Systems
Robotic surgery represents a cornerstone for surgical treatment of different diseases. Since the Da Vinci patent expiry, several new robotic systems entered the market in the effort to spread to a greater extent the benefits of…
- Trial name
- RSSQ (NCT07051941)
- Testing
- Validation of a satisfaction questionnaire for robotic surgeon
- Volunteers
- 100 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Abnormal Bowel Movement Such as Constipation, Diarrhea, Abdominal Pain
ID-JPL934 for Abnormal Bowel Movement
Probiotics, which are part of the human body, are microorganisms, which are known to have beneficial effects when consumed in a certain amount, and have the function of controlling intestinal flora and inhibiting inflammation.
- Trial name
- NCT03395626
- Testing
- ID-JPL934
- Where
- South Korea
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Coronary Artery Disease, Coronary Thrombosis
Safety and Efficacy Study Comparing 3 New Types of Coronary Stents
Background: Retrospective analyses of long-term BASKET findings identified patients with large drug-eluting stents (DES) (>2.5mm Stents) as patients at risk for late cardiac death/nonfatal myocardial infarction.
- Trial name
- NCT01166685
- Testing
- Everolimus-eluting stent, Bare-metal stent, Biodegradable Polymer-DES
- Where
- 8 sites in Austria, Denmark and 2 more
- Volunteers
- 2,291 people
- Sponsor
- University Hospital, Basel, Switzerland
Functional Dyspepsia
Phase Ⅱc Sutdy of Aolanti Weikang Tablets in FD PDS Patients
The purpose of this study is to evaluate the safety and validity of Aolanti Weipang Tablets in Patients with Postprandial Discomfort Syndrome of Functional Dyspepsia
- Trial name
- NCT03971383
- Testing
- Aolanti Weipang Tablets
- Where
- China
- Volunteers
- 236 people
- Sponsor
- Jiangxi Qingfeng Pharmaceutical Co. Ltd.
Glaucoma
VividFlo System Validation Study
This is a 10-participant study to assess the VividFlo System and surgical implantation using a modified technique.
- Trial name
- NCT07754201
- Testing
- VividFlo System
- Where
- Australia
- Volunteers
- 10 people
- Sponsor
- VividWhite Pty Ltd
Chronic Myeloid Leukemia
Radotinib as 3rd or Later Line Therapy in CP-CML
The purpose of this study is to determine whether radotinib is effective and safe for patients with chronic myeloid leukemia, chronic phase who are intolerable or resistant to prior 2 or more tyrosine kinase inhibitors.
- Trial name
- REVITAL (NCT02422719)
- Testing
- Radotinib
- Where
- South Korea
- Volunteers
- 73 people
- Sponsor
- Ulsan University Hospital
End Stage Renal Failure on Dialysis, End Stage Renal Disease on Dialysis
Human Factors Validation Testing for the Peripal System; a Manual Connection Assist Device for Peritoneal Dialysis Devices
It is estimated that there are currently over 3 million patients receiving dialysis treatment worldwide. With effective pre-dialysis counselling, a majority of patients choose the home-based therapy peritoneal dialysis (PD) but…
- Conditions
- End Stage Renal Failure on Dialysis, End Stage Renal Disease on Dialysis, Renal Failure, Peritoneal Dialysis
- Trial name
- NCT04292210
- Testing
- Perisafe
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Peripal AG
Eyes Dry Chronic, Chronic Conjunctivitis of Both Eyes
CDL Validation Study
Ocular surface photography is significantly limited in standardization and reproducibility. This reduces its applicability for clinical monitoring of acute or chronic disease.
- Conditions
- Eyes Dry Chronic, Chronic Conjunctivitis of Both Eyes, Limbal Stem-cell Deficiency, Eye Lesion
- Trial name
- NCT05461469
- Where
- Austria
- Volunteers
- 104 people
- Sponsor
- Occyo GmbH
Healthy Subject
Validation and Standardization of Test Methods and Evaluators for Testing of Hair Care Range of Products
An exploratory approach for validation and standardization of test methods and evaluators to conduct In-Vivo clinical safety and efficacy testing of hair care range of products. A total of 40 subjects will be enrolled.
- Trial name
- NCT05763888
- Testing
- No drug will given
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- NovoBliss Research Pvt Ltd
Clostridium Difficile-Associated Diarrhea
Safety and Validation of Efficacy of Oral Administration of the Food Additive Colostrum Derived Anti Clostridium Difficile Antibodies
This clinical study is designed to evaluate the safety and efficacy of oral administration of the food additive colostrum derived antibodies to Clostridium difficile for prevention of Clostridium difficile associated disease…
- Trial name
- NCT00747071
- Testing
- Colostrum
- Where
- Israel
- Sponsor
- Hadassah Medical Organization