Clinical trials: Vancomycin Dosage
Central Line-associated Bloodstream Infection (CLABSI), Catheter-related Bloodstream Infection
Effect of Vancomycin After Catheter Replacement
Randomized controlled trial of the effect of a single-dose intravenous Vancomycin after catheter replacement for suspected central line-associated bloodstream infection on resolution of infection in critically ill patients.
- Trial name
- VanCat (NCT04856878)
- Testing
- Vancomycin
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Pharmacokinetics and Pharmacodynamics
Vancomycin Dose Optimization in Obesity
The goal of this clinical trial is to learn how to optimize vancomycin dosing in obese adults based on weight and kidney function. It will also assess the safety of different vancomycin dosing strategies.
- Trial name
- NCT06601257
- Testing
- Vancomycin (IV)
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Vancomycin, Adult
Vancomycin Dose Adjustments Comparing Trough Levels to The AUC/MIC Method Using a Bayesian Approach in a Hospitalized Adult Population
This pilot study is a prospective, randomized, controlled, open-label trial to assess the feasibility of a randomized controlled trial of sufficient quality that would assess the efficacy and safety of vancomycin adjustments…
- Conditions
- Vancomycin, Adult, Area Under Curve
- Trial name
- VancoDATABayes (NCT04756895)
- Testing
- Vancomycin dose adjustment using the Bayesian method, Vancomycin dose adjustment using the trough level method
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- CR-CSSS Champlain-Charles-Le Moyne
Pneumonia, Staphylococcal
Vancomycin Dosage Strategy Based on a Trough Concentration Model
Study design: Allocation: Randomized Endpoint classification: Efficacy study Masking: Open label Primary purpose: Treatment Primary endpoint: Incidence of reaching the target serum trough concentration Secondary endpoint…
- Trial name
- NCT04088305
- Testing
- Individualized therapy
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Peking University Third Hospital
Vancomycin
Model-informed Precision Dosing of Vancomycin in Adults
The overall objective of this project is to investigate the utility of model-informed precision dosing (MIPD) of vancomycin in non-critically ill adults.
- Trial name
- NCT05535075
- Testing
- Vancomycin model-informed precision dosing, Vancomycin
- Where
- 2 sites in Belgium
- Volunteers
- 155 people
- Sponsor
- University Hospital, Ghent
Vancomycin
Precision Dosing of Vancomycin in Critically Ill Children
The overall objective of this project is to investigate the large-scale utility of MIPD of vancomycin at point-of-care in ICU children.
- Trial name
- BENEFICIAL (NCT04666948)
- Testing
- vancomycin model-informed precision dosing, Vancomycin
- Where
- 7 sites in Belgium
- Volunteers
- 314 people
- Sponsor
- University Hospital, Ghent