Clinical trials: Vaping Behavior
Cigarette Smoking, Vaping
Menthol and Mint Experimental Tobacco Marketplace (ETM) Study
Menthol cigarettes comprise almost one-third of the United States (US) market share and are disproportionately smoked by racial minorities.
- Trial name
- NCT04879225
- Testing
- Tobacco e-liquids, Menthol and Tobacco e-liquids, Mint, Menthol and Tobacco e-liquids
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Electronic Cigarettes
Assessment of Two New Electronic Cigarettes in Cigarette Smokers
The purpose of this study is to determine differences in nicotine delivery, user behavior, subjective effects, and physiological effects, when cigarette smokers use an two new electronic cigarette devices (JUUL and IQOS) relative…
- Trial name
- NCT03435562
- Testing
- JUUL electronic cigarette, IQOS electronic cigarette, Own Brand cigarette
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
E-cigarette Use
Middle School Cluster Randomized Controlled Trial (RCT) to Evaluate E-Cigarette Prevention Program: CATCH My Breath
This is a two-arm, cluster randomized trial designed to to evaluate the effectiveness of an e-cigarette curriculum [called the CATCH My Breath (CMB) program] in delaying the onset of e-cigarette use in middle schoolers.
- Trial name
- NCT04843501
- Testing
- CATCH My Breath (CMB) program for E-cigarette prevention among adolescents, Texas Education Agency (TEA) required tobacco prevention program
- Where
- United States
- Volunteers
- 2,059 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Depressive Symptoms, Depression
Goal2QuitVaping for Nicotine Vaping Cessation Among Adolescents
The purpose of this study is to evaluate a mobile application (app) called "Goal2QuitVaping" to help adolescents quit vaping nicotine. Goal2QuitVaping was developed by our research team to assist with quitting vaping.
- Conditions
- Depressive Symptoms, Depression, Adolescent Behavior
- Trial name
- NCT04951193
- Testing
- Behavioral Activation Therapy app, Treatment as Usual
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Nicotine Vaping, Nicotine Dependence
Assess the Influence of Nicotine Flux and Nicotine Form on Subjective Effects Related to Dependency
Electronic nicotine delivery systems (ENDS) heat and vaporize a nicotine-containing liquid to produce an aerosol that can deliver nicotine to the blood and the brain.
- Conditions
- Nicotine Vaping, Nicotine Dependence, Nicotine Addiction
- Trial name
- NCT05430334
- Testing
- e-liquid 1, e-liquid 2, e-liquid 3
- Where
- Lebanon
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Vaping, Nicotine Dependence
Varenicline for Nicotine Vaping Cessation in Adolescents
The study will test the hypothesis that varenicline, when added to behavioral and texting support for vaping cessation, will improve vaping abstinence rates in adolescents dependent on vaped nicotine over placebo plus behavioral…
- Trial name
- ViVA (NCT05367492)
- Testing
- Double Blind Varenicline, QuitVaping, This Is Quitting
- Where
- United States
- Volunteers
- 261 people
- Sponsor
- Massachusetts General Hospital
Nicotine Dependence, Cigarettes
The Role of Nicotine Dose and Route of Delivery in Affecting Adoption of E-cigarettes and Reducing Exposure to Toxic Combustion Products
This study plans to investigate whether using electronic cigarettes (e-cigarettes) or skin patches containing nicotine affects switching from smoking conventional combustible (burning) cigarettes.
- Trial name
- ENDS-Switch (NCT03492463)
- Testing
- Nicotine patch, E-cigarettes, Non-nicotine e-cigarettes
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Duke University
Nicotine Dependence, Electronic Cigarette Use
Methadone-Maintained Smokers Switching to E-Cigarettes
Participants in this randomized clinical trial will be methadone-maintained smokers interested in switching to electronic cigarettes (ECs).
- Trial name
- SHINE (NCT05206435)
- Testing
- Electronic Cigarette, Nicotine Lozenge
- Where
- United States
- Volunteers
- 183 people
- Sponsor
- Butler Hospital
Nicotine Dependence
The Effects of Menthol as Delivered by an Electronic Cigarette on the Desirability of Nicotine in Tobacco Users
This study will help determine if menthol administered by inhalation via electronic cigarettes (e-cigarette) changes the reinforcing effects of pure nicotine administered intravenously in cigarette smokers who smoke mentholated…
- Trial name
- NCT02102100
- Testing
- nicotine, menthol
- Where
- 2 sites in United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Yale University
Smoking Cessation
Enhanced E-cigarette Coaching Intervention for Dual Users of Cigarettes and E-cigarettes
The purpose of this study is to develop and pilot test an enhanced behavioral coaching intervention for dual users of cigarettes and electronic nicotine delivery systems (ENDS) who call tobacco quitlines for help quitting smoking.
- Trial name
- NCT03575468
- Testing
- Enhanced E-cigarette Coaching, Quitline treatment as usual
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Consumer Wellness Solutions
Cigarette Smoking, Nicotine Vaping
Promotion and Mitigation Factors Leading to Illegal Tobacco Purchases
This study will investigate the effects of promotion factors and mitigation strategies on legal and illegal tobacco purchases for different tobacco-user types.
- Trial name
- NCT06001840
- Testing
- Promotion factors, Mitigation strategies
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Virginia Polytechnic Institute and State University
Smoking Cessation
Varenicline for Treatment of E-cigarette Dependence
Varenicline is used to treat tobacco use dependence. It helps reduce cravings for tobacco use and decreases the pleasurable effects of cigarettes and other tobacco products.
- Trial name
- NCT05541497
- Testing
- Varenicline Tartrate
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Yale University
Nicotine Dependence, Smoking Cessation
Smoking Cessation and Reduction With an Electronic Nicotine Delivery Device (ENDD)
The study's major aim is to investigate the ability of a commercial Electronic Nicotine Delivery Device (ENDD) to induce long-term smoking reduction/abstinence in smokers unwilling to quit.
- Trial name
- NCT01195597
- Testing
- E-Cigarette 7.2 mg nicotine
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Catania
Smoking, Cigarette, Electronic Cigarettes
Evaluating New Nicotine Standards for Cigarettes - Project 3
This study is designed to examine how the nicotine content of cigarettes and the nicotine concentration and flavors in e-liquids influence responses to and use of these products in adolescent smokers.
- Trial name
- CENIC2-P3 (NCT03194256)
- Testing
- Spectrum Research Cigarettes
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Brown University
Cough
Effect of Electronic Cigarette Use on Cough Reflex Sensitivity
Although electronic cigarettes (e-cigs) are now widely used, very little information exists regarding the effect of electronic cigarette use (vaping) on the respiratory system.
- Trial name
- NCT02203162
- Testing
- electronic cigarette exposure
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Vaping, E-Cig Use
A Study of Cytisinicline for Vaping Cessation in Adult Smokers
This placebo-controlled Phase 2 study is being conducted at sites within the United States to evaluate the efficacy and safety profile of 3 mg cytisinicline administered TID for 12 weeks for vaping cessation.
- Trial name
- ORCA-V1 (NCT05431387)
- Testing
- cytisinicline, Behavioral support
- Where
- 5 sites in United States
- Volunteers
- 160 people
- Sponsor
- Achieve Life Sciences