Clinical trials: Vaping Cessation
Smoking Cessation, Vaping
Concentration Impact Nicotine Salt
Double-blind (for the two active arms), randomized, three-arm (two active and one control) clinical trial investigating factors (e.g.
- Trial name
- CINS (NCT04725656)
- Testing
- Smoking cessation counseling, Open system vape device and nicotine salt e-liquids
- Where
- Switzerland
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Vaping, Vaping Cessation
Social Media Support Groups for Adolescent Vaping Cessation
The purpose of this study is to pilot test feasibility and acceptability of the Quit the Hit Toolkit, a social media-based nicotine vaping cessation program for adolescents and young adults, adapted for use in community settings.
- Conditions
- Vaping, Vaping Cessation, Nicotine Dependence
- Trial name
- NCT07540780
- Testing
- Social Media Intervention
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
E-cigarette Use
Vape-Free Text-Messaging: Pilot Study
This is a small pilot randomized controlled trial to evaluate the feasibility, acceptability, and preliminary efficacy of the e-cigarette cessation text-messaging intervention with young adults in rural areas.
- Trial name
- NCT05906082
- Testing
- E-cigarette cessation text-messaging intervention, Standard care control using standard national resources
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jovan Gwon, PhD, RN, FIAAN
Smoking, Smoking Cessation
Preference-based Tools for Smoking Cessation Among Disadvantaged Smokers, a Pragmatic Randomised Controlled Trial
Objective: Our study aims to evaluate the effectiveness of the "STOP" (Sevrage Tabagique à l'aide d'Outils dédiés selon la Préférence: Smoking Cessation using preference-based tools) intervention, a preference-based smoking…
- Trial name
- STOP (NCT04654585)
- Testing
- The STOP intervention, Standard Care
- Where
- 15 sites in France
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Société de Formation Thérapeutique du Généraliste - Recherche
Smoking Cessation
Effectiveness of Different THR Products in Adult Population
The study is a two-arm, parallel randomized controlled trial (RCT) with a treatment period of 12 weeks, and long-term follow-up at 52 weeks which plans to enroll 258 smokers from general adult population.
- Trial name
- NCT05825924
- Testing
- E-Cigarette, Nicotine patch
- Where
- Pakistan
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Foundation for a Smoke Free World INC
Nicotine Dependence
Multimodal Neuroimaging Genetic Biomarkers of Nicotine AddictionSeverity
Background: Smoking is a difficult habit to quit, and some people find it more difficult to quit than others do. Nicotine is the substance in cigarettes that makes smoking so addictive.
- Trial name
- NCT01867411
- Where
- United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Cigarette Smoking
E-Cigarettes and Financial Incentives to Promote Tobacco Harm Reduction Among Adults Accessing Shelter Services
This randomized controlled trial evaluated the feasibility and potential efficacy of 1) e-cigarette switching (EC) or 2) e-cigarette switching + financial incentives for combustible cigarette cessation (EC+FI)
- Trial name
- EXCHANGE (NCT03743532)
- Testing
- E-cigarette Switching, Financial Incentives
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Healthy Smokers, Smoking Cessation
Efficacy and Safety of an Electronic Nicotine Delivery Device (E-Cigarette) Without Nicotine Cartridges
The study's major aim is to investigate the ability of a commercial Electronic Nicotine Delivery Device (E-Cigarette) to induce long-term smoking reduction/abstinence in smokers unwilling to quit.
- Trial name
- NCT01194583
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Catania
Smoking
Monitoring the Transition From Smoking to E-cigarettes
Electronic cigarettes (e-cigarettes) have proved very popular and a meteoric rise in their usage is currently under way. People purchase them as an aid to giving up smoking, to reduce cigarette consumption, to minimise withdrawal…
- Trial name
- NCT02752022
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- St George's, University of London
Nicotine Dependence, E-Cig Use
Research and Innovation to Stop E-cigarette/Vaping in Young Adults
The aim of this study is to test intervention components to help young adults quit vaping. A 2x2 factorial design will be used where all participants receive quitline-delivered behavioral phone counseling, and components to be…
- Trial name
- (RISE) (NCT04974580)
- Testing
- Nicotine patch, Phone Counseling, Digital Coaching
- Where
- United States
- Volunteers
- 508 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Smoking Cessation
The Effects of Combination Zonisamide and Bupropion on Switching to an Electronic Cigarette
This three-group randomized double-blind placebo-controlled trial (N=180) will evaluate the impact of combination zonisamide and bupropion on the process of switching from combustible cigarettes (CCs) to an e-cigarette.
- Trial name
- NCT05205811
- Testing
- Bupropion, Zonisamide, E-cigarette
- Where
- 2 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Rose Research Center, LLC
Tobacco Use, Smoking
Effectiveness of Tobacco Cessation Interventions in Sweden
Smoking is still one of the most important risk factors causing morbidity and mortality in Sweden. Every year, 12,000 Swedish citizens die prematurely from smoking, and smoking is responsible for up to 60% of the inequity in…
- Conditions
- Tobacco Use, Smoking, Cigarette Use, Electronic
- Trial name
- RSP (NCT04819152)
- Testing
- Tobacco cessation intervention
- Where
- 8 sites in Sweden
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Lund University
Obesity, Smoking Cessation
Trial for Harm Reduction With Incentives & Vaping E-cigarettes
The purpose of this study is to provide preliminary information on the effect of electronic nicotine delivery systems (ENDS) provisions and contingent incentives (CI) on smoking in individuals with overweight/obesity who smoke…
- Trial name
- THRIVE (NCT06111053)
- Testing
- ENDS, CI, No ENDS
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Brown University
Healthy Smokers, Smoking Cessation
Efficacy and Safety of an Electronic Nicotine Delivery Device (E-Cigarette)
The study's major aim is to investigate the ability of a commercial Electronic Nicotine Delivery Device (E-Cigarette) to induce long-term smoking reduction/abstinence in smokers unwilling to quit.
- Trial name
- NCT01164072
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Catania
Former Smoker, Non-Smoker
Vaped Phenanthrene
Some people who used to smoke cigarettes continue to be at higher risk of developing lung cancer, even years after quitting. This study will look to see if a specific chemical, phenanthrene, is broken down in the lungs of former…
- Trial name
- NCT07134426
- Testing
- D10-phenanthrene
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Cervical Dysplasia
Smoking Cessation in Women With Gynecological Conditions
This feasibility study will compare two smoking cessation methods, traditional nicotine replacement therapy and Electronic Nicotine Delivery Systems (electronic cigarettes) in patients with gynecological conditions.
- Trial name
- NCT01989923
- Testing
- Nicotine Replacement Therapy, Electronic Cigarettes
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Substance Withdrawal Syndrome
Does Abstinence From E-cigarettes Produce Withdrawal Symptoms?
The purpose of this study is to see whether adults who use e-cigarettes every day experience symptoms of nicotine withdrawal when they stop using e-cigarettes for 6 days.
- Trial name
- NCT02825459
- Testing
- Abstinence from e-cigarettes
- Where
- 2 sites in United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Tobacco Use Disorder, Nicotine Dependence
Young Adult Tobacco/Nicotine and Cannabis Co-use
The goal of this project is to better understand the relationship between tobacco/nicotine and cannabis using behavioral economics during a tobacco/nicotine quit attempt.
- Trial name
- YouthCAT (NCT06239350)
- Testing
- Counseling, Contingency management, Text-based support
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Tobacco Use Cessation, Tobacco Use
Development of UP2UTeacher for High School Youth
Tobacco use is increasing among youth in the U.S. However evidence for the long-term effectiveness of tobacco prevention and cessation programs for youth is limited.
- Conditions
- Tobacco Use Cessation, Tobacco Use, Electronic Cigarette Use
- Trial name
- UP2UTeacher (NCT05396911)
- Testing
- UP2UTeacher
- Where
- United States
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Role of Tobacco Harm Reduction in Smoking Cessation, Efficiency and Efficacy of E-cigarettes and Nicotine Pouches
Electronic Cigarettes and Nicotine Pouches for Smoking Cessation
Pakistan is one of the most vulnerable low- and middle-income countries with 29 million adult active tobacco users. Smoking cessation services are lacking as the tobacco control initiatives have largely failed to address the…
- Conditions
- Role of Tobacco Harm Reduction in Smoking Cessation, Efficiency and Efficacy of E-cigarettes and Nicotine Pouches, Adverse Effect of E-cigarettes and Nicotine Pouches
- Trial name
- NCT05715164
- Testing
- E-cigarettes device plus liquid, Nicotine Pouches, Basic care counseling about smoking cessation
- Where
- Pakistan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Alternative Research Initiative