Clinical trials: Variability
Gastrointestinal System--Abnormalities, Anxiety
Four-week Breathing Interventions on Gut Symptoms, Heart Rate Variability, and Psychological Measures in Runners
Recent research has suggested that stress and anxiety levels are associated with gastrointestinal (GI) symptoms in endurance athletes (runners, cyclists, triathletes).
- Conditions
- Gastrointestinal System--Abnormalities, Anxiety, Visceral Pain
- Trial name
- NCT04592718
- Testing
- Slow deep breathing plus breath counting, Normal-paced breathing plus breath counting
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Old Dominion University
Chronic Obstructive Pulmonary Disease (COPD)
Postural Control in Chronic Obstructive Pulmonary Disease
Postural control impairment is common in people with COPD (pwCOPD), which can increase the risk of falls and affect quality of life.
- Trial name
- NEUROTIGUE P (NCT06863246)
- Testing
- Evaluation of cognitive task on static balance, Evaluation of visual feedback on static balance
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
The Effect of Head Massage Therapy on the Autonomic Nervous System
The Effect of Head Massage Therapy on the Regulation of the Autonomic Nervous System
The autonomic nervous system (ANS) unconsciously regulates the activities of vital organ systems such as the respiratory, circulatory, and urinary systems.
- Trial name
- NCT02215486
- Testing
- Head Massage Therapy, Simple relaxation (No Head Massage)
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Children's & Women's Health Centre of British Columbia
Psychological Trauma
A Couples' Intervention Protocol for PTSD
Posttraumatic stress disorder (PTSD) is a multifaceted disorder resulting from intense and/or life-threatening trauma. PTSD sequelae often have a ripple effect on close others, including spouses and children.
- Trial name
- NCT05045859
- Testing
- CBCT for PTSD
- Where
- Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bar-Ilan University, Israel
Autism Spectrum Disorder
Emotional Proactive Brain Study in Adults With Autism Spectrum Condition
This project aims: to study behavioral and cerebral activity specificity (latency and amplitude of evoked potentials, time frequency maps and cerebral connectivity) in predictive process (top-down regulation) during visual…
- Trial name
- PREDEMAUT (NCT04069676)
- Testing
- EEG
- Where
- France
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Heart Rate Variability (HRV), Intracranial Pressure Change
Correlation Between the R-R Interval of the Electrocardiogram and the Intracranial Pulse Wave Interval Assessed by a Noninvasive Method in Healthy People
Heart rate variability (HRV) is a well-established cardiovascular and autonomic health metric in the medical literature. However, its applicability is limited by the difficulty of analysis and interpretation in clinical practice.
- Conditions
- Heart Rate Variability (HRV), Intracranial Pressure Change, Pulse Rate, Autonomic Nervous System Activity
- Trial name
- NCT07616674
- Testing
- Evaluate the correlation between R-R interval and R-R equivalent on the noninvasive intracranial compliance monitor (BRV) and evaluate their correspondence considering the Time domain (HR, NN, NN50, R
- Where
- Brazil
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Cervical Lordosis
Exploring Heart Rate Variability, EEG Pattern, and Corticomuscular Coherence After Cervical Sagittal Alignment Restoration
The goal of this Randomized clinical trial is to learn about how fixing neck curvature and head posture right away affects heart rate, brainwaves, and muscle coordination in college athletes.
- Trial name
- NCT06323746
- Testing
- Denneroll cervical traction orthodontic
- Where
- United Arab Emirates
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Sharjah
Physical Fitness
BPIT 5-Week Multi-Site Study: Movement Efficiency, Mobility & Neuromuscular Adaptation
This prospective, multi-site, single-arm interventional study evaluates the 5-Line Principle of Balanced Progressive Intensity Training (BPIT) over 5 weeks in healthy adults aged 18-65 years.
- Trial name
- BPIT_5LINE_369 (NCT07256717)
- Testing
- Balanced Progressive Intensity Training (BPIT) 5-Line Method
- Where
- 10 sites in United States, India
- Volunteers
- 369 people, healthy volunteers welcome
- Sponsor
- MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc.
Ultrasound, Catheterization
Success of Internal Jugular Vein Catheterization
Internal jugular vein cannulation can be performed with the blind technique under ultrasound (USG) guidance or using classical marker points.
- Conditions
- Ultrasound, Catheterization, Volume Status
- Trial name
- NCT05717556
- Testing
- Internal Jugular Vein Catheterization
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Elderly (people Aged 65 or More)
Leg Press Power Training with Visual Feedback Games Improves Physical, Cognitive, and Heart Health in Seniors
This study investigates the effects of lower limb leg press power training combined with visual feedback games on the physical performance, cognitive function, and heart rate variability (HRV) of older adults aged 65 and above.
- Trial name
- LPPT-VFG (NCT06714175)
- Testing
- Lower Limb Strength Training Program with Visual Feedback
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University
Exertion; Excess
Backpack Weight Impacts
Backpacking is an increasingly popular outdoor recreational activity. The base pack weight (BPW) includes gear that is not consumed or worn on the body: shelter, sleep system, weather-proofing layers and personal gear to ensure a…
- Trial name
- NCT04249986
- Testing
- The Borg Rating of Perceived Exertion
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Parkinson Disease
Safety Study to Autonomic Rehabilitation o Parkinson's Disease
Introduction: The Parkinson is one of the most common degenerative diseases of the central nervous system , mainly characterized by resting tremor , rigidity, akinesia and postural instability , also featuring the autonomic…
- Trial name
- NCT02680522
- Testing
- Exercise
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Metodista de Piracicaba
Healthy Patients
Evaluation of Heart Rate Variability in Third Lower Molars Surgeries
The purpose of this study is to use heart rate variability as a monitor of cardiovascular safety during third molar surgeries, using the Polar heart rate-meter.
- Trial name
- NCT01910337
- Testing
- Use the Polar Cardiac rate meter
- Where
- Brazil
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Renata Martins da Silva Prado
Healthy Volunteers, PHYSIOLOGICAL PHENOMENA
Study on Biomagnetic and Physiological Signals During Reiki Practice in Healthy Volunteers.
This study evaluates whether the practice of laying on of hands (Reiki) produces detectable biomagnetic and physiological modulations proximate to the human body in healthy volunteers.
- Conditions
- Healthy Volunteers, PHYSIOLOGICAL PHENOMENA, Biomagnetic and Physiological Effects of Laying on of Hands
- Trial name
- NCT07871981
- Testing
- Reiki Therapy, Mock Hand Placement
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Anhembi Morumbi University
Hereditary Angioedema
Autonomic Nervous System Profile in Hereditary Angioedema
The goal of this study is to compare the autonomic nervous system control of patients with hereditary angioedema to healthy individuals.
- Trial name
- ANS-HAE (NCT06408805)
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Abdominal Pain
Heart Rate Variability in Children With a Functional Gastrointestinal Disorder
The current study is designed to assess relationships between anxiety/stress, autonomic nervous system balance, and electrical activity in the stomach before and after eating/drinking in children with abdominal pain.
- Trial name
- NCT00195975
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Effect of Sedation on Heart Rate Variability
EFFECT OF DEXMEDETOMİDİNE AND MİDAZOLAM SEDATİON ON HEART RATE VARİABİLİTY AFTER CORONARY ARTERY BYPASS GRAFT SURGERY
The parasympathetic tone reduction and sympathetic tone enhancement, which are components of the autonomic nervous system (ANS) activity, increase the likelihood of malignant arrhythmias leading to ventricular fibrillation.
- Trial name
- NCT03601091
- Testing
- Precedex 200 MCG in 2 ML Injection, DORMICUM 5MG/5 ML
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital
Stress
The Effect of Massage Therapy to Control Night Shift Related Stress
Background: The sympathetic and parasympathetic branches (SNS and PNS) of the autonomic nervous system (ANS), keep our body in a state of balance, which can be disturbed in situations of uncontrolled stress.
- Trial name
- NCT02247089
- Testing
- Massage Therapy, Journal reading (No massage therapy)
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Laser Acupuncture, Meridian
The Effect of Laser Acupuncture in Different Meridians on the Autonomic Nervous System and Its Brain Mechanisms
Traditional Chinese acupuncture has a history of several thousand years. The World Health Organization has published guidelines describing the efficacy of acupuncture in the cure or relief of 64 different symptoms and conditions…
- Conditions
- Laser Acupuncture, Meridian, Heart Rate Variability, Brain Mechanism
- Trial name
- NCT05458713
- Testing
- Laser acupuncture
- Where
- Taiwan
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- China Medical University, Taiwan
Fertility, Implantation, Embryo
Cycle-to-cycle Variability of Progesterone in the Endometrium in Patients Undergoing an Euploid Blastocyst Transfer in a Hormone Replacement Therapy (HRT) Cycle (PROMICOFET)
This study looks at progesterone, a hormone that prepares the womb lining (endometrium) for pregnancy, in women having a frozen embryo transfer after IVF.
- Trial name
- PROMICOFET (NCT07818278)
- Testing
- Oestrogel® 0.75 mg (estradiol transdermal gel), Progesterone 200 mg vaginal capsules, Endometrial biopsy
- Where
- Belgium
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent