Clinical trials: Variability
Postprandial Hyperglycemia, Heart Rate Variability
Effect of Feet and Calf Heating on Glucose Tolerance
Determine the effect of feet and calf heating on glucose tolerance relative to thermoneutral control. Heat will be administered using hot water (40 degrees celsius).
- Trial name
- NCT04232098
- Testing
- Heat to ankle, Heat to calf
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Atrial Fibrillation
Effects of Exercise Training in Patients With Permanent Atrial Fibrillation
Atrial fibrillation (AF) is a common arrhythmia. The proposed patholophysiological mechanisms of AF include abnormal electrical conduction in atrium and sympathovagal imbalance with increased vagal tone.
- Trial name
- NCT01721863
- Testing
- Exercise training
- Where
- Taiwan
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Exercise, Cardiorespiratory Fitness
Addressing Individual Variability in Response to Exercise
In this proposal, the investigators challenge the assumption that following the physical activity guidelines implies benefit for ALL adults, and that if benefit is not achieved in response to first line therapy, it will be by…
- Trial name
- NCT04304092
- Testing
- Exercise
- Volunteers
- healthy volunteers welcome
- Sponsor
- Dr. Robert Ross
Duchenne Muscular Dystrophy
Wearable Technology to Evaluate Hyperglycemia and HRV in DMD
Duchenne muscular dystrophy (DMD) is an X-linked disorder that causes muscle wasting, cardiopulmonary failure, and premature death.
- Trial name
- NCT06124196
- Testing
- wearable technology
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Heart Rate Variability
Heart Rate Variability in Extracorporeal Membrane Oxygenation (ECMO) Patients
National Taiwan University Hospital is the leading center for care of patients with extracorporeal membrane oxygenation (ECMO). The predictable factors associated with outcomes are still lacking in patients with the ECMO support.
- Trial name
- NCT01247727
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Stress, Heart Rate Variability, Biomarker of Stress
Influence of the COvid-19 Epidemic on STRESS and Heart-Rate Variability in Health-care Workers
The COVID-19 pandemic is an exceptional and particularly anxiety-provoking health situation. In particular, for healthcare professionals who come into contact with patients who are contaminated or suspected of contamination, such…
- Conditions
- Stress, Heart Rate Variability, Biomarker of Stress, Burnout
- Trial name
- COVISTRESS HRV (NCT04954105)
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Hypotension
Predicting Hypotension Related to Spinal Anesthesia
This study aims to identify women at risk of low blood pressure (hypotension) after the usual cesarean anesthetic - a spinal anesthetic. Hypotension may be caused by dehydration.
- Trial name
- NCT01279889
- Where
- Canada
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Stress
Time, Touch, Attention and the Autonomic Nervous System
The purpose of this study is to describe the onset, duration and dose-response of interpersonal mindful compassion on respiratory rate and heart rate variability in healthy adults in order to prepare for research evaluating the…
- Trial name
- NCT01428674
- Testing
- Interpersonal Mindful Compassion with Touch, Reading while extending loving kindness
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wake Forest University
Individual Variability in (Poly)Phenol Metabolism
Investigation of in Vivo Endogenous and/or Exogenous Production of Phenolic Metabolites Using (un)Targeted Metabolomics
Plant (poly)phenols is what we call a large number of substances that are produced by plants as secondary plant metabolites, which means substances that are not used for their growth and development but are necessary for them to…
- Trial name
- ENDOPHENOL (NCT06028659)
- Testing
- Coffee, Water
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Parma
Drug Metabolism Phenotype
Biomarkers of CYP2D6 and CYP3A4 Variability in Pediatrics
Cytochrome P450 2D6 (CYP2D6) is an important enzyme in the body for breaking down many medications that are commonly used in children of various ages.
- Trial name
- NCT01118858
- Where
- 2 sites in United States
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Haemophilia
Inter Individual Variability in Initiation Pathway Activation and Regulation and Phenotypic Heterogeneity in Patients With Haemophilia A and B
Severe haemophilia A and B (SHA, SHB) are X - linked inherited bleeding disorders, characterised by factor VIII and IX levels of <1 IU/dL respectively.
- Trial name
- InPath (NCT03287999)
- Testing
- Thrombophilia screen, Initiation pathway analysis
- Where
- United Kingdom
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Royal Free Hospital NHS Foundation Trust
Diet-induced Thermogenesis
Inter-Individual Variability in Early Diet-Induced Thermogenesis After a Standardized Meal
This study aims to characterize how individuals differ in their metabolic response to food intake, specifically focusing on early diet-induced thermogenesis (DIT).
- Trial name
- NCT07610759
- Testing
- Standardized Liquid Meal
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Vitamin D Deficiency
The Variability of 25-hydroxyvitamin D Response From Crystalline 25-hydroxyvitamin D3
The investigators hypothesize that native vitamin D will have more variability in 25(OH)D dose response when compared to a given equipotent dose of 25-hydroxyvitamin D3.
- Trial name
- NCT01633658
- Testing
- cholecalciferol, 25(OH)D
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Creighton University
Schizophrenia, Bipolar
Heart Rate Changes in Schizophrenic and Bipolar Patients Under the Medication of Aripiprazole and Quetiapine
The goal of this research is investigating the heart rate changes in schizophrenic and bipolar patients under the medication of aripiprazole and quetiapine.
- Trial name
- HeartAriQue (NCT01047215)
- Testing
- Aripiprazole; Quetiapine
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Taichung Veterans General Hospital
Lipodystrophy
Carotid Doppler Peak Velocity Variation in Liposuction Fluid Management
This study aims to compare the hemodynamic parameters, postoperative plethysmography variability index, the total amount of postoperative intravenous fluid administration needed, and the urine output of two methods of fluid…
- Trial name
- NCT05930106
- Testing
- Intraoperative fluid ratio, Carotid Artery Doppler Peak Velocity Variation
- Where
- Mexico
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- TJ Plast Advanced Center for Plastic Surgery
Stress
The Impact of a Continuous Performance Task on the Stress Response
The goal of this clinical trial is to learn about the impact of taking a continuous performance attention test on the physiological stress response in college students.
- Trial name
- NCT06098352
- Testing
- PEBL Continuous Performance Task
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Redlands
HR Vaiability, Aerobic Physical Fitness,Blood Pressure, Blood Sugar Level, Blood HDL, LDL
Aerobic Exercise Training & the Autonomic System In Patients After Myocardial Infarction or Stroke
The purpose of this study is to examine the effect of Aerobic Physical Activity on the function of the Autonomic System in patients after Myocardial Infarction or Stroke.
- Trial name
- NCT00259948
- Testing
- Aerobic exercise training
- Where
- Israel
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Cerebral Hypoxia
The Effects of Hypobaria vs Hypoxia on Cerebral Functions.
The investigators will investigate the effect of hypobaria and hypoxia on physiological responses such as: oxygen saturation, heart rate, cerebral blood flow, cerebral oxygenation, brain's activity and concentration performance.
- Trial name
- Hypoxia (NCT03303118)
- Testing
- Hypoxia
- Where
- Switzerland
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Fliegerärztliches Institut
Heart Rate Variability
Short- and Long-term HRV Measurements After Osteopathic Myofascial Thoracic Manipulations
The adaptation of the heart to react to any stimulus is called heart rate variability (HRV). Moreover, HRV is now used as a health index.
- Trial name
- NCT04234958
- Testing
- Osteopathic manipulative treatment
- Where
- Canada
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Université du Québec a Montréal
Baro-reflex Sensitivity, Heart Rate Variability
Low Intensity Exercise in Different Normobaric/Hypobaric Normoxic/Hypoxic Conditions.
The main goal of this project is to investigate how low intensity cycling exercise (1.5W/kg, for 6 minutes) influences cerebral functions, such as: Cerebral blood flow, oxygenation, and other physiological variables in different…
- Conditions
- Baro-reflex Sensitivity, Heart Rate Variability, EEG, Microstates, Cerebral Blood Flow Regulation
- Trial name
- Hypoxia (NCT03439202)
- Testing
- Hypoxia
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fliegerärztliches Institut