Clinical trials: Variability
Perfusion
The Effects of Intravenous Fluids on Perfusion Index and Pleth Variability Index
This study is aimed to assess the effects of intravenously administered three fluid types on perfusion index and pulse variability index in patients during preoperative period. Patients will be randomly divided into three groups.
- Trial name
- NCT03048162
- Testing
- sodium chloride, Hydroxyethylstarch, Ringer-Lactate Infusion Solution Bag
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Comparison of HRV Biofeedback and Eurythmy Therapy as Stress Management Interventions for Female Nurses and Midwives
Stress Management Among Nurses and Midwives in Inpatient Care
This study compares two six-week stress-management programs for female nurses and midwives working in a hospital: heart rate variability biofeedback and Eurythmy Therapy.
- Trial name
- NCT07827092
- Testing
- HRV Biofeedback, Behavioral - Eurythmy Therapy (EYT)
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- ARCIM Institute Academic Research in Complementary and Integrative Medicine
Heart Rate Variability
The Heart of the Community Study
Community service providers (CSPs), such as promotores and other community health staff, play an essential role in preserving health and treating disease in underserved Hispanic/Latinx (HL) communities with disproportionately…
- Trial name
- NCT05560893
- Testing
- Relational Savoring Intervention
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Postprandial Hyperglycemia, Heart Rate Variability
Effect of Feet and Calf Heating on Glucose Tolerance
Determine the effect of feet and calf heating on glucose tolerance relative to thermoneutral control. Heat will be administered using hot water (40 degrees celsius).
- Trial name
- NCT04232098
- Testing
- Heat to ankle, Heat to calf
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Healthy Individuals
Effect of Kinesthetic Motor Imagery on Heart Rate, Heart Rate Variability, and Skin Resistance
Motor Imagery (MI) is defined as imagining an action in the mind without any explicit physical movement. MI is considered an "offline" process of the motor areas of the brain.
- Trial name
- NCT06482528
- Testing
- Motor Imagery
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Biological Rhythm, Drug Metabolism and Pharmacokinetics
A Temporal Variability Study of Remimazolam for General Anesthesia Induction and Maintenance
The purpose of this study was to observe and compare the differences in plasma concentration, dosage and carboxylesterase 1 activity of remimazolam when remimazolam is used for general anesthesia induction and maintenance at…
- Trial name
- NCT07079800
- Where
- China
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Jie Chen
Healthy
Efficacy, Transfer, and Neuro-functional Basis of a Memory Training Targeting Episodic Retrieval in Older Adults.
Aging leads to cognitive changes that affect memory, particularly episodic retrieval. These impairments are detrimental to seniors' quality of life.
- Trial name
- SPECTRA (NCT06110234)
- Testing
- Episodic Specificity Induction, Associative Memory
- Where
- Canada
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal
HIV Infections, Hyperlipidemia
Genetic Predictors of Variability in the Drug-drug Interaction Between Darunavir/Ritonavir and Pravastatin
Pravastatin (Pravachol) is approved by the Food and Drug Administration (FDA) and is used to treat high cholesterol. Darunavir (Prezista) and ritonavir (Norvir) are approved by the Food and Drug Administration (FDA) to treat HIV…
- Trial name
- NCT00630734
- Testing
- Pravastatin, Darunavir, Ritonavir
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Healthy
A Clinical Trial Investigating the Intra-subject Variability of Pharmacokinetics and Glucodynamics of BioChaperone Insulin Lispro U-100 Product and U-200 Product in Healthy Volunteers
This is a double-blinded, randomised, single-centre phase I pilot trial for exploring the feasibility of a pivotal clinical trial establishing bioequivalence between BioChaperone insulin lispro U-200 and BioChaperone insulin…
- Trial name
- NCT02529293
- Testing
- BioChaperone Lispro U-100, BioChaperone Lispro U-200
- Where
- Germany
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Adocia
COVID-19
Role of HLA Genes and Innate Immunity in the Phenotypic Variability of COVID-19
Case-control, prospective retrospective association study of patients infected with SARS-CoV2 and cured by COVID19. Recruited patients were divided into two cohorts (cases: patients with respiratory failure that required…
- Trial name
- 3490 (NCT05711836)
- Testing
- HLA-genotyping
- Where
- Italy
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Type 2 Diabetes
The Impact of Glucotoxicity on Gastric Emptying in Chinese Patients With Newly Diagnosed Type 2 Diabetes
Gastric emptying is now recognized as a major determinant of the blood glucose response to carbohydrate in both health and type 2 diabetes (T2D).
- Trial name
- NCT05284344
- Testing
- Anti-Diabetics
- Where
- China
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Adelaide
Diabetes Mellitus, Type 2
Cognitive Training for Diabetes Self-Management
The overall objective of this study is to determine the effects of a comprehensive cognitive rehabilitation intervention on biological, cognitive, and diabetes self-management outcomes.
- Trial name
- NCT04831775
- Testing
- Memory, Attention, and Problem Solving Skills for Diabetes, Brain Games
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Heart Rate Variability, Athletic Performance
The Relationship Between Heart Rate Variation and Athletic Performance in Basketball Players
This study was planned to explain the relationship between heart rate variability and their sportive performance in basketball players.
- Trial name
- NCT04779034
- Testing
- Measurement of heart rate variability
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Heart Rate Variability
Heart Rate Variability and Emotion Regulation
Previous research suggests that heart rate variability (HRV) biofeedback aimed at increasing HRV can reduce anxiety and stress. However, some mental quiescence practices that reduce HRV during the practice sessions also lead to…
- Trial name
- HRV-ER (NCT03458910)
- Testing
- HRV training
- Where
- United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Duchenne Muscular Dystrophy
Heart Rate Variability in Duchenne Muscular Dystrophy During Computer Task
HRV is attained using a Polar RS800CX. Then, evaluated through linear, non-linear and chaotic global techniques (CGT). Forty-five male subjects were included in the DMD group and age-matched with forty-five in the healthy Typical…
- Trial name
- NCT04607824
- Testing
- Duchenne Muscular Dystrophy group, Typical Development group
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Eccentric Exercise, Muscle Damage
Effects of Exercise-Induced Muscle Damage on Neuromuscular Complexity
This study will examine the effects of exercise-induced muscle damage, induced by eccentric exercise, on torque production, muscle oxygenation, and electromyographic activity of the knee extensors in healthy young men.
- Trial name
- EIMD-NMC (NCT07565376)
- Testing
- Isokinetic eccentric exercise
- Where
- Greece
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Cortical Excitability, Brain Stimulation
Neuroplastic Alterations of the Motor Cortex by Caffeine
Caffeine is a psychostimulant drug. It acts as a competitive antagonist at adenosine receptors, which modulate cortical excitability as well.
- Conditions
- Cortical Excitability, Brain Stimulation, Caffeine
- Trial name
- NCT04011670
- Testing
- 200 mg caffeine tablet, Non-active tablet
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Medical Center Goettingen
Depression, Couples (Persons)
Social Interaction and Compassion in Depression
The purpose of this study is to determine how a CBCT® (Cognitively Based Compassion-Training) for couples affect aspects of health and especially social interactions in depressed female patients and their romantic partners.
- Trial name
- SIDE (NCT03080025)
- Testing
- CBCT® (Cognitively Based Compassion-Training)
- Where
- Germany
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Effects of Standardized Physical Exercise on a Bicycle Ergometer on the Perfusion Index (PI) and Other Cardiovascular Parameters
Bicycle Ergometry and Peripheral Hemodynamics: a Pilot Study
This study examines how cycling on an exercise bicycle affects blood flow and heart and circulation in 12 healthy adult men. The main measurement is the perfusion index, which indicates how well blood is flowing through the small…
- Trial name
- NCT07830615
- Testing
- Standardized Bicycle Ergometer Exercise
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- ARCIM Institute Academic Research in Complementary and Integrative Medicine
Obesity, Insulin Resistance
Explore the Relationship Between Heart Rate Variability, Body Mass Index, Inflammation, and Insulin Resistance.
The findings will serve as a reference for clinical professionals to promote exercise among the general population for improving HRV.
- Conditions
- Obesity, Insulin Resistance, Overweight
- Trial name
- NCT05949710
- Testing
- aerobic exercise(AE)
- Where
- Taiwan
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- National Tainan Junior College of Nursing