Clinical trials: Variability
Epilepsy; Syndrome, Seizures of Localized Onset
Does Levetiracetam and Carbamazepine Impact the Autonomic Activity of Children With Self-limiting Focal Epilepsy?
The goal of this cross-sectional study is to learn about autonomic cardiac profile changes in children with self-limiting focal epilepsy using levetiracetam and carbamazepine in children with self-limiting focal epilepsy…
- Trial name
- levcbz (NCT06138847)
- Testing
- electroencephalogram
- Where
- Turkey (Türkiye)
- Volunteers
- 119 people
- Sponsor
- İpek Dokurel
Depressive Symptoms, Stress Disorder, Acute
Neurophysiological Mechanisms of Accelerated Resolution Therapy (ART)
In brief, ART is an innovative "mind-body" (body-centric) psychotherapy that makes use of established core components of trauma-focused therapy including imaginal exposure and imagery rescripting to promote memory…
- Conditions
- Depressive Symptoms, Stress Disorder, Acute, Prolonged Grief Disorder, Alcohol Abuse
- Trial name
- M-ART (NCT04121884)
- Testing
- Accelerated Resolution Therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of South Florida
Hypertension, Pregnancy Induced, Preeclampsia
Blood Pressure Variability Effect on Right Ventricular Strain in Women With Hypertensive Disorders With Pregnancy
The goal of this observational study is to learn about the potential effect of blood pressure variability changes on right ventricular strain in pregnant women with gestational hypertension or pre-eclampsia
- Trial name
- NCT06100484
- Testing
- Echocardiography
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aswan University
Acute Coronary Syndrome
Customization of Cardiac Readaptation Based on Force-velocity Profile and Heart Rate Variability
Cardiac readaptation aims to mitigate cardiovascular risks and enhance the quality of life among coronary patients. Our research laboratory has an international expertise in training optimization in top-athletes and a previous…
- Trial name
- PROPIU (NCT06107452)
- Testing
- training strategy with adaptation of training strategies to the ANS, training strategy (standard practice)
- Where
- France
- Volunteers
- 102 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Spinal Cord Injuries, Orthostatic Hypotension
Heart Rate Variability and Its Association With Symptom of Orthostatic Hypotension in Spinal Cord Injury
In this study, the SCI patients were sub-grouped on the basis of symptoms into symptomatic and asymptomatic groups and measured HRV during resting and tilt up tests to compare their cardiovascular autonomic functions.
- Conditions
- Spinal Cord Injuries, Orthostatic Hypotension, Heart Rate Variability
- Trial name
- NCT05982652
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Pusan National University Yangsan Hospital
Anxiety Disorder
Cipralex® for Anxiety Disorders in Adolescents
The primary objective is to examine whether Cipralex® is effective and safe in the treatment of anxiety disorders in youth. The secondary objective is to identify changes in arousal and stress response from pre- to post-treatment…
- Trial name
- CAP-E (NCT01293838)
- Testing
- Cipralex®
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Ottawa
Insomnia
Heart Rate Variability Biofeedback as Adjunctive Therapy to Self-help CBT-I
This study will examine the effect of Heart Rate Variability (HRV) biofeedback as adjunctive therapy to self-help Cognitive Behavioral Therapy on insomnia (CBT-I) in Chinese adult population.
- Trial name
- NCT05078268
- Testing
- HRV biofeedback training and self-help CBT-I, Self-help CBT-I only
- Where
- Hong Kong
- Volunteers
- 44 people
- Sponsor
- Chinese University of Hong Kong
Stress, Smoking Cessation
Sense2Stop:Mobile Sensor Data to Knowledge
The aim of this research is to build systems that can recognize when people are stressed and then provide them with relaxation prompts in the moment to reduce their likelihood of being stressed, smoking, or overeating in the near…
- Conditions
- Stress, Smoking Cessation, Overeating
- Trial name
- NCT03184389
- Testing
- Prompt to use smartphone apps for stress management
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Northwestern University
Thermogenesis by Different-dosage Ginger Flour Footbaths
Dose-Response Relationship of Ginger Flour Footbaths in Healthy Volunteers
A study to explore whether different dosages of ginger flour in footbaths cause different effects on warmth development as well as on general well-being and the autonomic nervous system.
- Trial name
- NCT04051476
- Testing
- 3-g footbath, 6-g footbath, 12-g footbath
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- ARCIM Institute Academic Research in Complementary and Integrative Medicine
Emergence Agitation, Heart Rate Variability (HRV)
Heart Rate Variability and Anxiety as Predictors of Emergence Agitation After Septorhinoplasty
This prospective observational study aims to evaluate whether preoperative heart rate variability (HRV) and anxiety are associated with, and can help predict, emergence agitation in adult patients undergoing elective…
- Conditions
- Emergence Agitation, Heart Rate Variability (HRV), Septorhinoplasty
- Trial name
- NCT07389135
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Konya City Hospital
Glycemic Response
Ethnic Variability in Glycemic and Hunger Satiety Response to Rice in Overweight Adults
Evidence has./ indicated increased risk of type 2 diabetes with white rice consumption in Asian population. It is shown that glycemic response to carbohydrate-containing food may differ in people of different ethnicities.
- Trial name
- NCT05336032
- Testing
- Food (rice)
- Where
- United Arab Emirates
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rashid Centre for Diabetes and Research
Intravenous Anesthetic Agent Overdose
Interest of a Tetanus Test at a Fixed Remifentanil Concentration Before Laryngoscopy and Skin Incision
Individually-tailored administration of the opioid analgesic component during general anaesthesia is still a challenge for the anesthesiologist.
- Trial name
- NCT02884310
- Testing
- Remifentanil adapted to SPI, Remifentanil fixed
- Volunteers
- 48 people
- Sponsor
- Erasme University Hospital
Fluid Loss
Fluid Management Based on Pleth Variability Index (PVI) Monitoring During High-risk Surgery
Oximetry monitoring is common practice in patients undergoing anesthesia. PVI continuous evaluation may be a possibility of agility and ease of obtaining accurate information about the state of cardiovascular responsiveness to…
- Trial name
- NCT01788293
- Testing
- Intervention group
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Hospital Regional de Presidente Prudente
Fluid Responsiveness, Modified Prone Position
Pleth Variability Index in Modified Prone Position or Knee-chest Position (Concord Position)
To investigate whether PVI predicts the fluid responsiveness in modified prone position undergoing posterior approach cervical operation.
- Trial name
- NCT04002193
- Testing
- volume expansion
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Asan Medical Center
Hemodynamics After Spinal Anesthesia
Premedication and Haemodynamics After Spinal Anesthesia
Blood pressure drop following spinal anesthesia is connected with sympathetic/parasympathetic activity which may be determinated by Heart Rate Variability (HRV) assessment.
- Trial name
- NCT01066247
- Testing
- Morphine hydrochloride; Midazolam, Midazolam
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Gdansk
Complications; Anesthesia, Spinal and Epidural, in Pregnancy
The Effect of the Timing of Colloid and Crystalloid Infusions on Postspinal Hypotension After Spinal Anesthesia for Caesarian Section
Prevention of postspinal hypotension after spinal anesthesia for caesarian section by use of preoperative or intraoperative volume replacement.
- Trial name
- NCT02680678
- Testing
- Colloid Preload, colloid co-load, Crystalloid preload
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Alcohol Drinking, Alcohol Abuse
Novel Real-world Methods in Social Drinkers and AUD
This research project proposes a novel approach to elucidate the biological adaptations associated with Alcohol Use Disorder and to assess whether such adaptations are predictive of higher alcohol craving in response to both…
- Conditions
- Alcohol Drinking, Alcohol Abuse, Alcohol Use Disorder
- Trial name
- ALR (NCT05155176)
- Testing
- Intensive Day Monitoring
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Yale University
Peripheral Neuropathy With Type 2 Diabetes
A Physiologic Comparison of Two Approaches to Treating Peripheral Neuropathy
Diabetic peripheral neuropathy is one of the most common and costly microvascular complications of diabetes impacting more than 50% of patients and costing more than 10.1 billion dollars annually.
- Trial name
- NCT05577390
- Testing
- Intraneural Facilitation Therapy Treatment, Standard Physical Therapy Treatment
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Loma Linda University
Restless Legs Syndrome
Cardiovascular Variability, Heart Rate Response, and Electromyogram Power Associated With Periodic Leg Movements.
Periodic leg movements during sleep is associated with microarousals and a stimulation of the sympathetic nervous system. The knowledge of this autonomic activation may help understanding the increase of cardiac risk observed in…
- Trial name
- PLMS (NCT03076541)
- Testing
- standard 24-h ambulatory polysomnography
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Fluid Management
Pleth Variability Index and Fluid Management During Surgery
Pleth Variability Index (PVI) seems to be an ideal parameter to guide fluid management: dynamic parameter and non-invasive. PVI could guide fluid management during surgery and optimization of the plethysmographic-derived…
- Trial name
- NCT00816153
- Testing
- PVI-guided fluid management
- Where
- Belgium
- Volunteers
- 97 people
- Sponsor
- Université Catholique de Louvain
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