Clinical trials: Variability
Depressive Symptoms
Comparing Paroxetine and Duloxetine on Cardiovascular Measures
This double-blind placebo-controlled trial is designed to test and to compare the cardiovascular profile of paroxetine controlled release (CR) with duloxetine in outpatients with depressive symptoms.
- Trial name
- NCT00136383
- Testing
- paroxetine versus duloxetine
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Duke University
Chronic Heart Failure, Type 2 Diabetes
Prognostic Impact of Diabetes and Weight Variability in Telemonitored Heart Failure
This observational cohort study evaluates the prognostic impact of diabetes, comorbidity burden, and short-term weight variability among adults with chronic heart failure enrolled in a nationwide remote patient monitoring program…
- Conditions
- Chronic Heart Failure, Type 2 Diabetes, Diabetes (DM)
- Trial name
- DM-HF-Tele (NCT07561866)
- Testing
- Diabetes Status, Comorbidity Burden, Weight variability
- Where
- France
- Volunteers
- 16,556 people
- Sponsor
- Satelia
Duchenne Muscular Dystrophy
Heart Rate Variability in Duchenne Muscular Dystrophy During Computer Task
HRV is attained using a Polar RS800CX. Then, evaluated through linear, non-linear and chaotic global techniques (CGT). Forty-five male subjects were included in the DMD group and age-matched with forty-five in the healthy Typical…
- Trial name
- NCT04607824
- Testing
- Duchenne Muscular Dystrophy group, Typical Development group
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Anti-Psychotic, Management of Manifestations of Psychotic Disorders
Assessment of Intra-subject Variability in the Bioavailability of Chlorpromazine Hydrochloride
Cycle Pharmaceuticals Ltd. (Cycle) is developing an oral tablet formulation of Chlorpromazine Hydrochloride and intends to conduct bioequivalence trials to demonstrate its similarity to the RLD.
- Conditions
- Anti-Psychotic, Management of Manifestations of Psychotic Disorders, Treatment of Schizophrenia, Control Nausea and Vomiting
- Trial name
- NCT02943213
- Testing
- Chlorpromazine Hydrochloride
- Where
- South Africa
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cycle Pharmaceuticals Ltd.
Heart Failure
Apple Watch Heart Failure Study
This is a pilot/feasibility study on the accuracy of HRV as measured by the Apple Watch on heart failure patients who are admitted to the hospital with heart failure exacerbation.
- Trial name
- NCT04510779
- Testing
- Apple Watch
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Tufts Medical Center
Healthy, Swimming
EFFECTS OF FOAM ROLLING ON HRV IN ELITE SWIMMERS
The present study aimed to evaluate the effects of foam rolling (FR) on recovery by examining selected time-domain and frequency-domain heart rate variability (HRV) parameters in elite swimmers following intensive interval sprint…
- Conditions
- Healthy, Swimming, Autonomic Nervous System Function, Recovery
- Trial name
- HRV-SWIMMING (NCT07641062)
- Testing
- Swimming+FoamRollingRecovery, SwimmingRecovery
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Uludag University
Laser Acupuncture, Meridian
The Effect of Laser Acupuncture in Different Meridians on the Autonomic Nervous System and Its Brain Mechanisms
Traditional Chinese acupuncture has a history of several thousand years. The World Health Organization has published guidelines describing the efficacy of acupuncture in the cure or relief of 64 different symptoms and conditions…
- Conditions
- Laser Acupuncture, Meridian, Heart Rate Variability, Brain Mechanism
- Trial name
- NCT05458713
- Testing
- Laser acupuncture
- Where
- Taiwan
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- China Medical University, Taiwan
Exposure to Man-made Visible Light
Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 3 of 7)
NOTE: This is the third of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674.
- Trial name
- NCT02882542
- Testing
- Visible light exposure
- Where
- Switzerland
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Bern
Athletic Performance, Sports Performance
Effects of Afternoon Napping, Caffeine, and Standardised Active Recovery on Evening Athletic Performance
This study evaluated whether afternoon napping, caffeine ingestion, and a standardised active recovery and nutritional protocol could influence evening physical and cognitive performance in healthy university athletes.
- Conditions
- Athletic Performance, Sports Performance, Exercise Performance, Circadian Rhythm
- Trial name
- NAP-CAF-REC (NCT07652424)
- Testing
- Afternoon Nap, Caffeine, Standardised Active Recovery and Nutritional Protocol
- Where
- Tunisia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Higher Institute of Sport and Physical Education of Sfax
Obesity, Aging
Variability of Physical Assessments in an Older Population That is Overweight or Obese
Variability of physical assessments in an older population that is overweight or obese.
- Trial name
- NCT05174923
- Testing
- Short Performance Physical Battery (SPPB Test), 30 Second Chair Stand Test (30CST), Hand grip dynamometry
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- Versanis Bio, Inc.
Hyperhidrosis
Cardiac Autonomic Changes After Endoscopic Thoracic Sympathectomy For Essential Palmar Hyperhidrosis
Essential palmar hyperhidrosis (EPH) is a pathological condition of excessive sweating of the hands due to an unexplained over-activity of the T2 and T3 sympathetic fibers.
- Trial name
- NCT02733497
- Testing
- Sympathectomy, Sympathicotomy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Anesthesia Induced Hypotension, Hypotension Drug-Induced
Comparison of Pleth Variability Index vs. Diastolic Shock Index for Predicting Hypotension During Anesthesia Induction
This study aims to explore the frequent occurrence of hypotension during anesthesia induction due to anesthetic drugs or fasting. Predicting this condition is important for patient safety and anesthesia management.
- Trial name
- NCT06589674
- Testing
- Pulse variability index measurement, Diastolic shock index
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people
- Sponsor
- Kocaeli City Hospital
ESRD (End Stage Renal Disease), Dialysis
Laser Acupuncture for Fatigue in Hemodialysis Patients
The goal of this clinical trial is to learn if laser acupuncture (low-level laser therapy) works to treat fatigue and improve quality of life in adults with end-stage renal disease (ESRD) undergoing hemodialysis.
- Conditions
- ESRD (End Stage Renal Disease), Dialysis, Fatigue
- Trial name
- LA-HD-Fatigue (NCT07538310)
- Testing
- Low-Level Laser Acupuncture (LA)
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Taipei City Hospital
Premature, Behavior, Child
Effects of Oriental Music on Preterm Infants
The goal of this study is to explore the effect of oriental music on premature infants' physiological and behavioral parameters during their hospital stay in the NICU.
- Trial name
- NCT04565210
- Testing
- Music exposure, Silence
- Where
- Lebanon
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Coronary Artery Disease
The Effect of Training on Endothelial Function, Progression of Disease,Inflammation, Heart Rate Variability and Mental Health After Percutaneous Coronary Intervention
The Efector study is an open, randomized and controlled trial assessing the effect of regular exercise training on endothelial function, inflammatory markers, progression of disease, heart rate variability and mental health in…
- Trial name
- EFECTOR (NCT00469950)
- Testing
- exercise training
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Helse Stavanger HF
Healthy Volunteers
An Analysis of Healthy Caucasian Knees
In current literature, databases of healthy knee anatomy and function are confined to small sample sizes or singular imaging modalities.
- Trial name
- PC-CT KNEE (NCT07470671)
- Testing
- CT scan images of the knee, EOS scan of full leg, Ultrasound-based gap analysis
- Where
- Belgium
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Menopause, Exercise
Ambulatory and Blood Pressure Variability Responses to Exercise in Normotensive and Hypertensive Women
This study evaluated the differences between normotensive and hypertensive menopausal women in ambulatory and blood pressure variability responses to combined aerobic and resistance exercise.
- Conditions
- Menopause, Exercise, Blood Pressure, High
- Trial name
- NCT03531034
- Testing
- Combined Exercise Training
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Federal University of Uberlandia
Cholesterol Variability, Trained Immunity
LDL-c Level Variability and Trained Immunity
Statin treatment significantly reduces the incidence of cardiovascular events. However, cholesterol variability is associated with the risk of adverse events such as mortality, myocardial infarction, and stroke.
- Trial name
- NCT05790499
- Testing
- Atorvastatin
- Where
- China
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
COVID-19
Effects of Unsupervised Inspiratory Muscle Training on Ventilation Variability in Post-covid-19 Patients.
Dysfunctional breathing and persistent hypocapnia can be associated with many of the symptoms experienced by patients such as dyspnea, fatigue, chest pain and palpitations.
- Trial name
- NCT06362499
- Testing
- Experimental Group
- Where
- 2 sites in Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio Grande do Norte
Perioperative Care, Fluid Therapy
Paired Comparison of SVV and PVI Accuracy
This study will compare two operating-room monitors-stroke volume variation (SVV, from the arterial line) and the Pleth Variability Index (PVI, from the pulse oximeter)-to see which one more accurately predicts whether giving a…
- Conditions
- Perioperative Care, Fluid Therapy, Monitoring, Physiologic, Hemodynamics
- Trial name
- NCT07260890
- Testing
- Stroke Volume Variation (SVV) monitoring, Pleth Variability Index (PVI) monitoring
- Where
- South Korea
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital
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