Clinical trials: Variability
Dietetics, Diet, Healthy
The Effects of External Cues Versus Internal Cues Messaging on Heart Rate Variability and Affect
This randomized controlled trial will assess the effects of External Cues focused messaging (i.e., government recommendations of MyPlate) compared to Internal Cues focused messaging (i.e., intuitive eating).
- Conditions
- Dietetics, Diet, Healthy, Nutrition Therapy, Affect
- Trial name
- NCT05309941
- Testing
- Internal Cues Nutrition Messaging, External Cues Nutrition Messaging
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Long COVID, Post-COVID Conditions
Transcranial Direct Current Stimulation for Long COVID Brain Fog and Fatigue
Long COVID can cause persistent symptoms such as fatigue, cognitive difficulties commonly described as brain fog, reduced exercise tolerance, and impaired quality of life.
- Conditions
- Long COVID, Post-COVID Conditions, Fatigue, Cognitive Dysfunction
- Trial name
- NEUROSTIM-LC (NCT07709234)
- Testing
- Transcranial Direct Current Stimulation
- Volunteers
- 20 people
- Sponsor
- University of Las Palmas de Gran Canaria
Type 2 Diabetes Mellitus
Effect of a Protein-Creatine-Omega3-Vitamin D Supplement on Glycemic Variability in Mexican Patients With Type 2 Diabetes
This study aims to evaluate the effect of a daily nutritional supplement containing whey protein, creatine, omega-3 fatty acids, and vitamin D on blood sugar fluctuations in adults with recently diagnosed type 2 diabetes.
- Trial name
- PROVID-DM (NCT06920667)
- Testing
- Protein-Creatine-Omega-3-Vitamin D Supplement
- Volunteers
- 40 people
- Sponsor
- Héctor Iván Saldívar Cerón
Cancer, Stress, Psychological
Brief Mindfulness Chatbot Intervention for Cancer Patients
This study tests a new digital tool for hospitalized cancer patients. The tool is a chatbot on LINE, a popular messaging app. The chatbot is called Mindbot. Mindbot leads a 10-minute mindfulness practice each day.
- Trial name
- MINDBOT-CA (NCT07811739)
- Testing
- Mindbot: Brief Mindfulness-Based LINE Chatbot with Virtual Reality
- Volunteers
- 66 people
- Sponsor
- Taipei Medical University
Hypertension, Old Age
Study on Blood Pressure Variability and Frailty in the Older People
Observational prospective single-center, non-profit study. Primary objective of the study: To determine if the hypotensive phenotype, defined as one episode of daytime systolic blood pressure (SBP) <90 mmHg (or two episodes of…
- Trial name
- HypoPHrail (NCT06868069)
- Testing
- Diagnostic tests and questionnaires
- Where
- Italy
- Volunteers
- 220 people
- Sponsor
- Istituto Auxologico Italiano
Sympathetic; Imbalance
Comparison of Heart Rate Variability Measurement on the Arm and Chest in Vagus Nerve Stimulation
Healthy participants will be included in this study by invitation and randomised into three groups. Participants in each group will receive bilateral transcutaneous vagus nerve stimulation with the same frequency, current transit…
- Trial name
- NCT07000175
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Autonomic Nervous System, Cardiovascular Outcomes
Impact of Caffeine Intake on Autonomic Parameters in the Exercise of Strength
The objective of this study was to evaluate the variability of the heart rate of exercise physicists with and without caffeine intake.
- Trial name
- NCT03899675
- Testing
- Caffeine
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pernambuco
Myocardial Infarction With Nonobstructive Coronary Arteries
The Prognostic Role of Indices of Sympathetic Nervous System Overdrive in MINOCA
Myocardial infarction with non-obstructive coronary arteries (MINOCA) occurs in 1-13% of all patients with acute myocardial infarction (AMI).
- Trial name
- PRISMA (NCT04681612)
- Testing
- MSNA, Heart Rate Variability, Blood Pressure Variability
- Where
- Greece
- Volunteers
- 150 people
- Sponsor
- Hippocration General Hospital
Motor Activity
Variability of Healthy People and People After Stroke Results in the Box and Block Test
Main aim of the study is to find out how many attempts of each subtest in the Box and Block Test should be done in clinical practice during testing people after stroke who are 20-64 years old.
- Trial name
- NCT05925231
- Testing
- Box and Block Test
- Where
- 2 sites in Czechia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Burnout, Professional
Impact of Heart Rate Variability Modulation on Stress Management Among Physicians
The purpose of this research is to examine a wearable device called Apollo that emits gentle vibrations found to benefit mood, energy, and focus. We want to understand how it affects burnout in physicians.
- Trial name
- NCT05731856
- Testing
- Apollo Wearable
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Michelle Thompson
Heart Rate Variability, Emergency Department
Heart Rate Variability At the Emergency Department
In this study investigators want to examine if heart rate variability at hospital entry predicts prognosis in participants with severe disease.
- Trial name
- NCT05093439
- Testing
- Heart Rate Variability
- Where
- Belgium
- Volunteers
- 532 people
- Sponsor
- University Hospital, Ghent
Biological Rhythm, Drug Metabolism and Pharmacokinetics
A Temporal Variability Study of Remimazolam for General Anesthesia Induction and Maintenance
The purpose of this study was to observe and compare the differences in plasma concentration, dosage and carboxylesterase 1 activity of remimazolam when remimazolam is used for general anesthesia induction and maintenance at…
- Trial name
- NCT07079800
- Where
- China
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Jie Chen
Children Receiving Prednisone or Prednisolone or Methylprednisolone or Hydrocortisone
Pharmacokinetics of Glucocorticoids in Children (GLUCOPED)
The purpose of this study is to determine individual susceptibility factors (drug interactions, genetic factors such as enzyme polymorphism…) to explain wide interindividual variability towards corticosteroids (prednisone…
- Trial name
- GLUCOPED (NCT02252237)
- Testing
- Pharmacokinetic
- Where
- France
- Volunteers
- 146 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Type 2 Diabetes Mellitus, Continuous Glucose Monitoring
Primary Care - Continuous Glucose Monitoring
Introduction and objective: The key to optimal diabetes management is tight glucose control. Hemoglobin A1c is the gold standard to assess glycemic control but in cases of unrecognized hypoglycemia, confusing nighttime events or…
- Trial name
- PC-COSMO (NCT03253237)
- Testing
- continuous glucose monitoring (CGM)
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- University of Zagreb
Low Back Pain
Effects of Yoga Versus Passive Modality on Pain, Disability, Salivary Cortisol Concentrations, Brain- Derived Neurotropic Factor, Heart Rate Variability and Immune Functions Among Patients With Chronic Low Back Pain: A Randomized Controlled Trial
This study may clarify a potential promising mechanism and clearest evidence to support the value of yoga as a therapeutic option for reducing chronic low back pain.
- Trial name
- NCT02244645
- Testing
- passive modality, Yoga treatment
- Where
- Taiwan
- Volunteers
- 86 people
- Sponsor
- Chang Bing Show Chwan Memorial Hospital
Cardiogenic Shock,, With ECMO or IABP Support,
The Analysis of Heart Rate Variability With 24hrs Holter ECG and Serum Cardiac Fibrosis Markers in Critical Illness Patients Who Are With Cardiogenic Shock, With ECMO or IABP Support, or With APACH II Score >25)
The study is to show the prognostic factor of HRV parameter and cardiac fibrosis markers in critical illness patients
- Conditions
- Cardiogenic Shock,, With ECMO or IABP Support,, With APACH II Score >25)
- Trial name
- NCT01993745
- Where
- Taiwan
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Ovulation
Heart Rate Variability During the Menstrual Cycle
In this study, women will be required to wear a chest heart rate monitor and wrist heart rate monitor daily and collect daily early morning urine samples for the duration of one complete menstrual cycle.
- Trial name
- NCT04382001
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- SPD Development Company Limited
Type 2 Diabetes Mellitus
Effects of Gemigliptin Versus Sitagliptin or Glimepiride With Metformin on Glucose Variability(MAGE, Glucose SD) Patients With Type 2 DM(STABLE Study)
To compare efficacy and safety of initial combination therapy of Gemigliptin versus Sitagliptin or Glimepiride with Metformin on Glucose Variability(MAGE, Glucose SD) in Patients With Type 2 Diabetes Mellitus.
- Trial name
- STABLE (NCT01890629)
- Testing
- Gemigliptin + Metformin / Sitagliptin + Metformin / Glimepiride + Metformin
- Where
- South Korea
- Volunteers
- 69 people
- Sponsor
- LG Life Sciences
Type 2 Diabetes Mellitus
Bioavailability of Technosphere® Insulin Versus Subcutaneous Regular Human Insulin in Type 2 Diabetes
The purpose of this study is to compare the kinetics and biodynamics of inhaled Technosphere Insulin with those of subcutaneous (SC) regular human insulin.
- Trial name
- NCT00511719
- Testing
- Technosphere Insulin, Actrapid
- Volunteers
- 13 people
- Sponsor
- Mannkind Corporation
Cesarean Section
Heart Rate Variability to Predict Hypotension Following Spinal Anesthesia in Cesarean Delivery
Based on the patient's heart rate variability, the analgesia nociception index (ANI) measures the activity of the autonomic nervous system and the sympathetic/parasympathetic nervous system and expresses it as a numerical value…
- Trial name
- NCT04979039
- Testing
- analgesia nociception index (ANI) monitoring
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Bundang Hospital
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