Clinical trials: Variability
Type 2 Diabetes Mellitus
Effect of Administration of Resveratrol on Glycemic Variability in Individuals With Type 2 Diabetes Mellitus
Type 2 diabetes mellitus [ T2DM ] has quickly become the epidemic of the XXI century and challenging global health . Estimates of the World Health Organization [ WHO ] indicate that globally , from 1995 to date has nearly tripled…
- Trial name
- NCT02549924
- Testing
- Resveratrol
- Where
- Mexico
- Volunteers
- 22 people
- Sponsor
- University of Guadalajara
Lipohypertrophy, Type 1 Diabetes Mellitus
Ultrasound Classification and Grading of Lipohypertrophy and Its Impact on Glucose Variability in Type 1 Diabetes
This study will use ultrasound to characterise lipohypertrophy(LH) and assess the impact of LH on glucose variability in adults with type 1 diabetes.
- Trial name
- TITANIC (NCT03669770)
- Where
- United Kingdom
- Volunteers
- 75 people
- Sponsor
- King's College London
Muscle Soreness, Delayed-onset Muscle Soreness
Effects of ReWin(d) Supplementation on the Recovery of DOMS Induced by Acute Exercice
The study will assess the recovery and performance of young athletes suffering from muscle damage induced by physical exercise. Model by comparing the safety and efficacy of ReWin(d) supplemention during 4 weeks to placebo over…
- Trial name
- NCT03961022
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Natural Origins
Infection, Bacterial
Plasma Concentrations of Amoxicillin Administered in High-doses During the First Week of Treatment (MAX-AMOX)
Amoxicillin is the most prescribed antibiotic in France. High dose intravenous amoxicillin, (dosage greater than or equal to 150 mg / kg / day or 12 g per day for patients over 80 kg) is used in the treatment, in particular, of…
- Trial name
- MAX-AMOX (NCT04070469)
- Testing
- Amoxicillin
- Where
- France
- Volunteers
- 142 people
- Sponsor
- University Hospital, Clermont-Ferrand
COPD
Monitoring Chronic Obstructive Pulmonary Disease Patients at Home by a Forced Oscillation Technique Device
Chronic obstructive pulmonary disease (COPD) is a pathological condition whose progression is characterized by stable periods broken up by intermittent acute exacerbations of the symptoms, during which a severe inflammatory…
- Trial name
- NCT01552031
- Where
- 5 sites in Australia, Italy
- Volunteers
- 80 people
- Sponsor
- Raffaele Dellaca
Premature Ejaculation
Vagus Nerve Stimulation in Premature Ejaculation
Introduction: Premature ejaculation (PE), one of the most common sexual dysfunctions in men, negatively affects sexual function and quality of life.
- Trial name
- NCT07300774
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Mental Health, Social Interaction
PeerScreen Trial - Reducing Screen Media Use in Peer-groups of Young People
The purpose of the PeerScreen trial is to investigate whether reducing screen media use affects mental health, social interaction, sleep, physical activity, heart rate variability, and behavioral patterns in young people aged 13…
- Conditions
- Mental Health, Social Interaction, Sleep, Physical Activity
- Trial name
- NCT07531290
- Testing
- Screen media reduction
- Where
- Denmark
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Occupational Stress, Sleep Quality
Curcumin Nano Patch and Autonomic Function in Shift-Working Healthcare Professionals
This randomized, open-label, placebo-controlled crossover study compares a curcumin-containing patch with a cooling placebo patch without curcumin in healthcare professionals who work rotating shifts.
- Trial name
- NCT07910279
- Testing
- Curcumin Nano Patch
- Where
- Taiwan
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Healthy
Human Genomic Population Structure and Phenotype-genotype Variation in ADME Genes in Four Populations
Physicians know that their patients can react differently to the same medical treatment: for some of them, the drug will prove inefficient, whereas for others it might provoke side-effects, sometimes rather serious.
- Trial name
- NCT02789527
- Testing
- Phenotyping, Genotyping
- Where
- 4 sites in Czechia, Ethiopia and 2 more
- Volunteers
- 367 people, healthy volunteers welcome
- Sponsor
- Estella S. Poloni
Diabetes Mellitus Type 2
Medium-term Effects of a Polyphenol-rich Beverage Based on Red Grape Pomace Extract on Non-alcoholic Fatty Liver Disease, Cardiometabolic Risk Profile and Gut Microbiota in Subjects with Type 2 Diabetes
Nonalcoholic fatty liver disease (NAFLD) is a liver disease characterized by an abnormal accumulation of fat not due to alcohol or drug consumption that can evolve into steatohepatitis (NASH), fibrosis and cirrhosis.
- Trial name
- PoLiFat (NCT06895018)
- Testing
- Supplementation with Polyphenol Rich Drink
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Federico II University
Type 1 Diabetes Mellitus
PK and PD Within-Subject Variability of a Single Dose of Afrezza Inhaled Technosphere Insulin in Patients With Diabetes Mellitus Type 1 (T1DM)
Primary Objective: To characterize the within-subject variability in systemic exposure pharmacokinetic (PK) to insulin of a replicate single dose of Afrezza inhaled Technosphere Insulin (TI) in T1DM patients in a euglycemic clamp…
- Trial name
- NCT02485327
- Testing
- Technosphere Insulin SAR439065 Afrezza®
- Where
- Germany
- Volunteers
- 22 people
- Sponsor
- Mannkind Corporation
Healthy Volunteer
The Accuracy and Efficacy of AI-driven tVNS Algorithm
Pain, including somatic and visceral pain, is a common symptom. Persistent pain can lead to repetitive visits to hospitals and can limit patients' daily activities, which can result in tremendous medical cost and lower quality of…
- Trial name
- NCT05215756
- Testing
- transcutaneous vagal nerve stimulation
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Exertion; Excess
Backpack Weight Impacts
Backpacking is an increasingly popular outdoor recreational activity. The base pack weight (BPW) includes gear that is not consumed or worn on the body: shelter, sleep system, weather-proofing layers and personal gear to ensure a…
- Trial name
- NCT04249986
- Testing
- The Borg Rating of Perceived Exertion
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Diabetes Mellitus, Type 2, Metabolic Disease
The Effect on Metabolism, Food Intake and Preferences of a Knockout Gene Variant Involved in Carbohydrate Metabolism
Around 10% has type 2 diabetes in Greenland, despite being a practically unknown disease only six decades ago. The drastic increase is of great concern, especially considering the transition that have occurred during the same…
- Conditions
- Diabetes Mellitus, Type 2, Metabolic Disease, Sucrose Intolerance Congenital, Sucrase Isomaltase Deficiency
- Trial name
- NCT05375656
- Testing
- Cross-over study
- Where
- 2 sites in Greenland
- Volunteers
- 38 people
- Sponsor
- Steno Diabetes Center Copenhagen
Stroke
Motor Control Physical Therapist Support Stroke
The purpose of this study is to systematically determine the effect of unnecessary physical therapist assistance in individuals after stroke during the practice of an upper limb task on an individual's task performance and their…
- Trial name
- NCT04856527
- Testing
- Physical therapist support
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Cincinnati
No Condition
Matcha Green Tea Effects at Rest and During Moderate-intensity Exercise in Females
Intake of the green tea catechin epigallocatechin (EGCG) increased fat oxidation during walking. It is also known to reduce blood pressure and improve body composition.
- Trial name
- NCT05882942
- Testing
- Matcha green tea
- Where
- 2 sites in United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Chichester
Schizophrenia
Therapeutic Drug Monitoring for Individualized Clozapine Therapy
The purpose of this study is to evaluate the factors affecting the occurrence of adverse drug reactions (glucose and lipid metabolism abnormality, changes in liver function index and sleeping tendency) and clinical effects in…
- Trial name
- NCT03523741
- Testing
- Clozapine
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital
Hypertension, Postmenopausal Symptoms
Yoga Poses and Breath Control Cardiovascular Changes in Hypertensive Post-Menopause Women
Autonomic and endothelial imbalance in post menopause women raise the need to manage cardiovascular risk. Yoga poses and breathing control present controversial results on prevention and treatment of hypertension..
- Trial name
- YOGINI (NCT03137849)
- Testing
- Yoga Poses, Breath Control, Stretching exercises
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Diabetes
Effects of Remimazolam and Propofol on Anesthesia Induction
The patients with diabetes who underwent laparoscopic cholecystectomy in the general surgery department of the Second Hospital of Shanxi Medical University were selected.
- Trial name
- NCT06009055
- Testing
- Remimazolam, Propofol
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Zheng Guo
Hyperlipidemia
Effect of Genes on Rosuvastatin Therapy for Hyperlipidemia
Previous studies indicate that the variant status of detoxification proteins is different among Taiwanese and other ethnic groups.
- Trial name
- NCT00934258
- Testing
- rosuvastatin,fenofibrate, CYP2C9, UGT1A1, UGT1A3, OATP2, BCRP
- Sponsor
- National Taiwan University Hospital
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